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T. Uchihara · SciRah

Researcher profile · Semantic Scholar

T. Uchihara

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T. Uchihara — researcher profile on SciRah

h-index: 47
Works: 274
Citations: 9,464

Most-cited papers

Reader response: Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB consortium
T. Uchihara, S. Toru
2018Neurology458 citations
Semantic Scholar
PART is part of Alzheimer disease
C. Duyckaerts, H. Braak, J. Brion, L. Buée +7 more
2015Acta Neuropathologica306 citations Open access
Semantic Scholar
Propagation of alpha-synuclein pathology: hypotheses, discoveries, and yet unresolved questions from experimental and human brain studies
T. Uchihara, B. Giasson
2015Acta Neuropathologica218 citations Open access
Semantic Scholar
Cholesterol-functionalized DNA/RNA heteroduplexes cross the blood–brain barrier and knock down genes in the rodent CNS
T. Nagata, Chrissa A. Dwyer, K. Yoshida-Tanaka, Kensuke Ihara +20 more
2021Nature Biotechnology123 citations
Semantic Scholar
Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice
Shigeto Sato, T. Uchihara, T. Fukuda, Sachiko Noda +6 more
2018Scientific Reports116 citations Open access
Semantic Scholar
Brainstem tau pathology in Alzheimer’s disease is characterized by increase of three repeat tau and independent of amyloid β
Miho Uematsu, Ayako Nakamura, Momoko Ebashi, K. Hirokawa +2 more
2018Acta Neuropathologica Communications84 citations Open access
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Quantitative correlation between cardiac MIBG uptake and remaining axons in the cardiac sympathetic nerve in Lewy body disease
Makoto Takahashi, M. Ikemura, T. Oka, T. Uchihara +7 more
2015Journal of Neurology Neurosurgery & Psychiatry66 citations
Semantic Scholar
Isoform transition from four-repeat to three-repeat tau underlies dendrosomatic and regional progression of neurofibrillary pathology
M. Hara, K. Hirokawa, S. Kamei, T. Uchihara
2013Acta Neuropathologica55 citations
Semantic Scholar
Pretangles and neurofibrillary changes: Similarities and differences between AD and CBD based on molecular and morphological evolution
T. Uchihara
2014Neuropathology (Kyoto. 1993)50 citations
Semantic Scholar
TDP-43 Pathology Progression Along the Olfactory Pathway as a Possible Substrate for Olfactory Impairment in Amyotrophic Lateral Sclerosis
T. Takeda, M. Iijima, T. Uchihara, T. Ohashi +3 more
2015Journal of Neuropathology and Experimental Neurology45 citations Open access
Semantic Scholar
Propagation of Aβ, tau and α-synuclein pathology between experimental models and human reality: prions, propagons and propaganda
T. Uchihara, B. Giasson, W. Paulus
2015Acta Neuropathologica43 citations Open access
Semantic Scholar
An order in Lewy body disorders: Retrograde degeneration in hyperbranching axons as a fundamental structural template accounting for focal/multifocal Lewy body disease
T. Uchihara
2017Neuropathology (Kyoto. 1993)42 citations
Semantic Scholar
Parkinson's disease: Is it a consequence of human brain evolution?
N. Diederich, D. J. Surmeier, T. Uchihara, S. Grillner +1 more
2019Movement Disorders40 citations Open access
Semantic Scholar
Clinical course of pathologically confirmed corticobasal degeneration and corticobasal syndrome
I. Aiba, Yuichi Hayashi, Takayoshi Shimohata, Mari Yoshida +49 more
2023Brain Communications36 citations Open access
Semantic Scholar
Tau pathology in aged cynomolgus monkeys is progressive supranuclear palsy/corticobasal degeneration- but not Alzheimer disease-like -Ultrastructural mapping of tau by EDX-
T. Uchihara, Kentaro Endo, Hiromi Kondo, S. Okabayashi +4 more
2016Acta Neuropathologica Communications30 citations Open access
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Ultrastructural differences in pretangles between Alzheimer disease and corticobasal degeneration revealed by comparative light and electron microscopy
Shinsui Tatsumi, T. Uchihara, I. Aiba, Y. Iwasaki +3 more
2014Acta Neuropathologica Communications27 citations Open access
Semantic Scholar
The Evolution-Driven Signature of Parkinson's Disease.
N. Diederich, T. Uchihara, S. Grillner, C. Goetz
2020Trends in Neurosciences26 citations Open access
Semantic Scholar
Development of demyelinating lesions in progressive multifocal leukoencephalopathy (PML): Comparison of magnetic resonance images and neuropathology of post‐mortem brain
D. Ono, Y. Shishido‐Hara, Saneyuki Mizutani, Y. Mori +6 more
2019Neuropathology (Kyoto. 1993)26 citations Open access
Semantic Scholar
Neurofibrillary changes undergoing morphological and biochemical changes – How does tau with the profile shift of from four repeat to three repeat spread in Alzheimer brain?
T. Uchihara
2020Neuropathology (Kyoto. 1993)21 citations
Semantic Scholar
Amygdala TDP-43 Pathology in Frontotemporal Lobar Degeneration and Motor Neuron Disease
T. Takeda, D. Seilhean, I. Le Ber, S. Millecamps +4 more
2017Journal of Neuropathology and Experimental Neurology21 citations
Semantic Scholar
Local extension of HMGB1 in atherosclerotic lesions of human main cerebral and carotid arteries.
T. Umahara, T. Uchihara, Shun‐ichi Koyama, T. Hashimoto +3 more
2014Histology and Histopathology20 citations
Semantic Scholar
How to demix Alzheimer-type and PSP-type tau lesions out of their mixture -hybrid approach to dissect comorbidity-
Momoko Ebashi, Yoshinori Ito, Miho Uematsu, Ayako Nakamura +3 more
2019Acta Neuropathologica Communications19 citations Open access
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JC Virus Inclusions in Progressive Multifocal Leukoencephalopathy: Scaffolding Promyelocytic Leukemia Nuclear Bodies Grow With Cell Cycle Transition Through an S-to-G2–Like State in Enlarging Oligodendrocyte Nuclei
Y. Shishido‐Hara, T. Yazawa, M. Nagane, K. Higuchi +5 more
2014Journal of Neuropathology and Experimental Neurology19 citations Open access
Semantic Scholar
Dendritic retraction, but not atrophy, is consistent in amyotrophic lateral sclerosis-comparison between Onuf’s neurons and other sacral motor neurons-
T. Takeda, T. Uchihara, Y. Nakayama, Ayako Nakamura +5 more
2014Acta Neuropathologica Communications17 citations Open access
Semantic Scholar
Neuropathological Staging of Spinocerebellar Ataxia Type 2 by Semiquantitative 1C2‐Positive Neuron Typing. Nuclear Translocation of Cytoplasmic 1C2 Underlies Disease Progression of Spinocerebellar Ataxia Type 2
S. Koyano, S. Yagishita, Y. Kuroiwa, F. Tanaka +1 more
2014Brain Pathology16 citations Open access
Semantic Scholar
14-3-3 protein sigma isoform co-localizes with phosphorylated α-synuclein in Lewy bodies and Lewy neurites in patients with Lewy body disease.
K. Wakabayashi, T. Umahara, K. Hirokawa, H. Hanyu +1 more
2018Neuroscience Letters15 citations
Semantic Scholar
Three-dimensional surface models of autopsied human brains constructed from multiple photographs by photogrammetry
H. Shintaku, Mari Yamaguchi, S. Toru, M. Kitagawa +3 more
2019PLoS ONE14 citations Open access
Semantic Scholar
Time-dependent and lesion-dependent HMGB1-selective localization in brains of patients with cerebrovascular diseases.
T. Umahara, T. Uchihara, K. Hirokawa, K. Hirao +4 more
2018Histology and Histopathology14 citations
Semantic Scholar
Secondary cardiac involvement in anti-SRP-antibody-positive myopathy: an 87-year-old woman with heart failure symptoms as the first clinical presentation
Arika Hara, Ryota Amano, Hiroaki Yokote, Masahide Ijima +7 more
2020BMC Neurology13 citations Open access
Semantic Scholar
Olfactory dysfunction related to TDP-43 pathology in amyotrophic lateral sclerosis.
T. Takeda, T. Uchihara, S. Kawamura, T. Ohashi
2014Clinical Neuropathology13 citations
Semantic Scholar
Effects of local reduction of endogenous α-synuclein using antisense oligonucleotides on the fibril-induced propagation of pathology through the neural network in wild-type mice
T. Sano, Tetsuya Nagata, Satoe Ebihara, K. Yoshida-Tanaka +7 more
2024Acta Neuropathologica Communications12 citations Open access
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Perirhinal accumulation of neuronal alpha‐synuclein in a multiple system atrophy patient with dementia
M. Saito, M. Hara, Momoko Ebashi, Akihiko Morita +6 more
2017Neuropathology (Kyoto. 1993)12 citations
Semantic Scholar
14-3-3 eta isoform colocalizes TDP-43 on the coarse granules in the anterior horn cells of patients with sporadic amyotrophic lateral sclerosis.
T. Umahara, T. Uchihara, N. Shibata, Ayako Nakamura +1 more
2016Brain Research11 citations
Semantic Scholar
Conventional magnetic resonance imaging key features for distinguishing pathologically confirmed corticobasal degeneration from its mimics: a retrospective analysis of the J-VAC study
Keita Sakurai, A. Tokumaru, Mari Yoshida, Yuko Saito +45 more
2024Neuroradiology10 citations Open access
Semantic Scholar
Neuropathology of SCA34 showing widespread oligodendroglial pathology with vacuolar white matter degeneration: a case study
Kokoro Ozaki, T. Irioka, T. Uchihara, A. Yamada +9 more
2021Acta Neuropathologica Communications10 citations Open access
Semantic Scholar
Detection of AD-specific four repeat tau with deamidated asparagine residue 279-specific fraction purified from 4R tau polyclonal antibody
Momoko Ebashi, S. Toru, Ayako Nakamura, S. Kamei +3 more
2019Acta Neuropathologica10 citations Open access
Semantic Scholar
Does This Adult Patient With Jolt Accentuation of Headache Have Acute Meningitis?
H. Tamune, Takaie Kuki, T. Kashiyama, T. Uchihara
2018Headache10 citations
Semantic Scholar
Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease
N. Nihonmatsu-Kikuchi, Xiu-jun Yu, Yoshiki Matsuda, N. Ozawa +12 more
2021Communications Biology9 citations Open access
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Decreased plasma ghrelin in male ALS patients is associated with poor prognosis.
U. Nagaoka, Toshio Shimizu, T. Uchihara, T. Komori +2 more
2021Neurosciences research8 citations
Semantic Scholar
Essential autophagic protein Beclin 1 localizes to atherosclerotic lesions of human carotid and major intracranial arteries.
T. Umahara, T. Uchihara, K. Hirao, S. Shimizu +3 more
2020Journal of Neurological Sciences8 citations
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An autopsy case of corticobasal syndrome with pure diffuse Lewy Body Disease
Keiko Ichinose, Mutsufusa Watanabe, Saneyuki Mizutani, T. Tanizawa +2 more
2021Neurocase7 citations
Semantic Scholar
Essential roles of plexin-B3+ oligodendrocyte precursor cells in the pathogenesis of Alzheimer’s disease
N. Nihonmatsu-Kikuchi, Xiu-jun Yu, Yoshiki Matsuda, N. Ozawa +9 more
2020bioRxiv7 citations Open access
Semantic Scholar
Novel neuronal cytoplasmic inclusions in a patient carrying SCA8 expansion mutation
T. Yokoyama, M. Ishiyama, K. Hasegawa, T. Uchihara +1 more
2014Neuropathology (Kyoto. 1993)7 citations
Semantic Scholar
Different outcomes from different cohorts: how to validate jolt accentuation?
T. Uchihara
2014American Journal of Emergency Medicine6 citations
Semantic Scholar
Immunohistochemical study of pseudohypertrophy of the inferior olivary nucleus.
K. Ogawa, S. Kamei, K. Ichihara, K. Uehara +4 more
2014Clinical Neuropathology5 citations
Semantic Scholar
Parallel Appearance of Polyglutamine and Transactivation-Responsive DNA-Binding Protein 43 and Their Complementary Subcellular Localization in Brains of Patients With Spinocerebellar Ataxia Type 2.
S. Koyano, S. Yagishita, Mikiko Tada, H. Doi +2 more
2022Journal of Neuropathology and Experimental Neurology4 citations
Semantic Scholar
Comorbid argyrophilic grain disease in an 87-year-old male with spinocerebellar ataxia type 31 with dementia: a case report
S. Toru, Shoko Ishida, T. Uchihara, K. Hirokawa +2 more
2020BMC Neurology4 citations Open access
Semantic Scholar
Leptin upregulation in advanced multiple system atrophy with hypocholesterolemia and unexpected fat accumulation
U. Nagaoka, Toshio Shimizu, T. Uchihara
2015Neurological Sciences4 citations
Semantic Scholar
Lateralized Cortical Involvement and Contralateral Parkinsonism without Basal Ganglia Involvement in Two Autopsy Cases of Corticobasal Syndrome-Alzheimer's Disease
Taku Homma, H. Takubo, Kazushi Takahashi, S. Matsubara +6 more
2014Journal of Alzheimer's Disease4 citations
Semantic Scholar
Parallel gold enhancement of quantum dots 565/655 for double-labelling correlative light and electron microscopy on human autopsied samples
Miho Uematsu, K. Mikami, Ayako Nakamura, Ryosuke Takahashi +3 more
2022Scientific Reports3 citations Open access
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