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M. D. Edwards · SciRah

Researcher profile · Semantic Scholar

M. D. Edwards

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M. D. Edwards — researcher profile on SciRah

h-index: 20
Works: 34
Citations: 1,440

Most-cited papers

The structure of an open form of an E. coli mechanosensitive channel at 3.45 Å resolution
Wenjian Wang, Susan S. Black, M. D. Edwards, S. Miller +5 more
2008Science207 citations Open access
Semantic Scholar
Mechanosensitive channels in bacteria: signs of closure?
I. Booth, M. D. Edwards, Susan S. Black, Ulrike Schumann +1 more
2007Nature Reviews Microbiology152 citations
Semantic Scholar
Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel
M. D. Edwards, Yue-Zhou Li, Sanguk Kim, S. Miller +7 more
2005Nature Structural &Molecular Biology133 citations
Semantic Scholar
Characterization of three novel mechanosensitive channel activities in Escherichia coli
M. D. Edwards, Susan S. Black, Tim Rasmussen, A. Rasmussen +4 more
2012Channels126 citations Open access
Semantic Scholar
Domain organization of the MscS mechanosensitive channel of Escherichia coli
S. Miller, W. Bartlett, S. Chandrasekaran, S. Simpson +2 more
2003EMBO Journal117 citations Open access
Semantic Scholar
YbdG in Escherichia coli is a threshold-setting mechanosensitive channel with MscM activity
Ulrike Schumann, M. D. Edwards, Tim Rasmussen, W. Bartlett +2 more
2010Proceedings of the National Academy of Sciences of the United States of America109 citations Open access
Semantic Scholar
The Closed Structure of the MscS Mechanosensitive Channel
S. Miller, M. D. Edwards, Cafer Ozdemir, I. Booth
2003Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Gating the bacterial mechanosensitive channels: MscS a new paradigm?
M. D. Edwards, I. Booth, S. Miller
2004Current Opinion in Microbiology57 citations
Semantic Scholar
The conserved carboxy‐terminus of the MscS mechanosensitive channel is not essential but increases stability and activity
Ulrike Schumann, M. D. Edwards, Chan Li, I. Booth
2004FEBS Letters53 citations Open access
Semantic Scholar
Pore Mutations of the Escherichia coli MscS Channel Affect Desensitization but Not Ionic Preference
M. D. Edwards, W. Bartlett, I. Booth
2007Biophysical Journal50 citations Open access
Semantic Scholar
Modulation of GABAA receptors and inhibitory synaptic currents by the endogenous CNS sleep regulator cis‐9,10‐octadecenoamide (cOA)
G. Lees, M. D. Edwards, Abdul A. Hassoni, C. Ganellin +1 more
1998British Journal of Pharmacology46 citations Open access
Semantic Scholar
modulation of Recombination Human γ-aminobutyric Acid-a Receptors by Isoflurane : influence of the Delta Subunit
G. Lees, M. D. Edwards
199834 citations Open access
Semantic Scholar
Sensing bilayer tension: bacterial mechanosensitive channels and their gating mechanisms.
I. Booth, Tim Rasmussen, M. D. Edwards, Susan S. Black +3 more
2011Biochemical Society Transactions31 citations
Semantic Scholar
The role of tryptophan residues in the function and stability of the mechanosensitive channel MscS from Escherichia coli.
A. Rasmussen, Tim Rasmussen, M. D. Edwards, D. Schauer +3 more
2007Biochemistry31 citations
Semantic Scholar
Identification of mutations that alter the gating of the Escherichia coli mechanosensitive channel protein, MscK
Chan Li, M. D. Edwards, Hochterl Jeong, J. Roth +1 more
2007Molecular Microbiology29 citations Open access
Semantic Scholar
Physiological analysis of bacterial mechanosensitive channels.
I. Booth, M. D. Edwards, Susan S. Black, Ulrike Schumann +4 more
2007Methods in Enzymology28 citations
Semantic Scholar
Characterisation of rat superficial superior colliculus neurones: firing properties and sensitivity to GABA.
M. D. Edwards, Anne‐Marie White, B. Platt
2002Neuroscience27 citations
Semantic Scholar
Tryptophan in the Pore of the Mechanosensitive Channel MscS
Tim Rasmussen, M. D. Edwards, Susan S. Black, A. Rasmussen +2 more
2009Journal of Biological Chemistry22 citations Open access
Semantic Scholar
The Role of Bacterial Channels in Cell Physiology
I. Booth, M. D. Edwards, Ewan Murray, S. Miller
200522 citations
Semantic Scholar
Modulation of a recombinant invertebrate γ‐aminobutyric acid receptor‐chloride channel complex by isoflurane: effects of a point mutation in the M2 domain
M. D. Edwards, G. Lees
1997British Journal of Pharmacology20 citations Open access
Semantic Scholar
Properties of the Mechanosensitive Channel MscS Pore Revealed by Tryptophan Scanning Mutagenesis
Tim Rasmussen, A. Rasmussen, Shivani Singh, Heloisa F. Galbiati +3 more
2015Biochemistry19 citations Open access
Semantic Scholar
Structure–Function Relations of MscS
I. Booth, M. D. Edwards, S. Miller, Chan Li +3 more
20079 citations
Semantic Scholar
Bacterial ion channels.
I. Booth, M. D. Edwards, S. Miller
2003Biochemistry9 citations
Semantic Scholar
Modulation of Recombination Human gamma‐Aminobutyric Acid sub A Receptors by Isoflurane: Influence of the Delta Subunit
G. Lees, M. D. Edwards
1998Anesthesiology9 citations
Semantic Scholar
The hemocyanin of the Californian black sea hare, Aplysia vaccaria Winkler.
T. T. Herskovits, M. D. Edwards, M. G. Hamilton
1995Comparative Biochemistry and Physiology Part B Comparative Biochemistry8 citations
Semantic Scholar
Mechanosensitive Channels: Their Mechanisms and Roles in Preserving Bacterial Ultrastructure During Adaptation to Environmental Changes
I. Booth, S. Miller, A. Rasmussen, Tim Rasmussen +1 more
20085 citations
Semantic Scholar
MOLECULAR MODE OF ACTION OF THE NEUROPROTECTIVE AGENT BW619C89
M. D. Edwards, M. Leach, G. Lees
19944 citations
Semantic Scholar
Analysis of Novel Mechanosensitive Channel Activities in Escherichia Coli
M. D. Edwards, I. Booth
20112 citations Open access
Semantic Scholar
Identification of mutations that alter the gating of the Escherichia coli mechanosensitive channel protein, MscK
Chan Li, M. D. Edwards, Hotcherl Jeong, J. Roth +1 more
2007Molecular Microbiology2 citations Open access
Semantic Scholar
The Di-decameric Hemocyanin of the Atlantic Murex Snail, Muricanthus fulvescens (Sowerby)
T. T. Herskovits, C. Kieran, M. D. Edwards, M. G. Hamilton
19912 citations
Semantic Scholar
IR Spectroscopy of Protein and Peptide-Membrane Interactions: In Situ Strategies for Tracking Fusion, Remodelling, and Refolding
Jessica J Li, Michael Wong, Lauren Lin, V. Bianchi +2 more
20111 citations Open access
Semantic Scholar
The Ktn Domain and Its Role as a Channel and Transporter Regulator
I. Booth, M. D. Edwards, Banuri Gunasekera, Chan Li +1 more
20051 citations
Semantic Scholar
Sometimes you see them, sometimes you don't: IPSCs in the rat superficial superior colliculus
M. D. Edwards, B. Platt
2003Experimental Brain Research1 citations
Semantic Scholar
In vitro potency and mode of action of ANQ9040: a novel fast acting muscle relaxant
G. Lees, I. Munday, M. D. Edwards, R. M. Jones
1994British Journal of Pharmacology0 citations Open access
Semantic Scholar

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Susan S. Black×8
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G. Lees — researcher profile on SciRah

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Chan Li — researcher profile on SciRah

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T. T. Herskovits — researcher profile on SciRah