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Alexey J. Merz · SciRah

Researcher profile · Semantic Scholar

Alexey J. Merz

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Alexey J. Merz — researcher profile on SciRah

h-index: 31
Works: 61
Citations: 4,748

Most-cited papers

A Type VI Secretion System of Pseudomonas aeruginosa Targets a Toxin to Bacteria
Rachel D. Hood, Pragya Singh, F. Hsu, Tüzün Güvener +12 more
2010Cell Host and Microbe919 citations Open access
Semantic Scholar
Pilus retraction powers bacterial twitching motility
Alexey J. Merz, M. So, M. Sheetz
2000Nature868 citations
Semantic Scholar
Vps-C Complexes: Gatekeepers of Endolysosomal Traffic
D. Nickerson, C. L. Brett, Alexey J. Merz
2009Current Opinion in Cell Biology256 citations Open access
Semantic Scholar
Vacuole fusion at a ring of vertex docking sites leaves membrane fragments within the organelle.
Li Wang, E. Seeley, W. Wickner, Alexey J. Merz
2002Cell236 citations Open access
Semantic Scholar
Interdependent assembly of specific regulatory lipids and membrane fusion proteins into the vertex ring domain of docked vacuoles
Rutilio A. Fratti, Y. Jun, Alexey J. Merz, N. Margolis +1 more
2004Journal of Cell Biology219 citations Open access
Semantic Scholar
Efficient termination of vacuolar Rab GTPase signaling requires coordinated action by a GAP and a protein kinase
C. L. Brett, Rachael L. Plemel, Braden T. Lobingier, M. Vignali +2 more
2008Journal of Cell Biology151 citations Open access
Semantic Scholar
Subunit organization and Rab interactions of Vps-C protein complexes that control endolysosomal membrane traffic
Rachael L. Plemel, Braden T. Lobingier, C. L. Brett, C. Angers +4 more
2011Molecular Biology of the Cell148 citations Open access
Semantic Scholar
Hierarchy of protein assembly at the vertex ring domain for yeast vacuole docking and fusion
Li Wang, Alexey J. Merz, Kevin M. Collins, W. Wickner
2003Journal of Cell Biology141 citations Open access
Semantic Scholar
A cycle of Vam7p release from and PtdIns 3-P–dependent rebinding to the yeast vacuole is required for homotypic vacuole fusion
C. Boeddinghaus, Alexey J. Merz, R. Laage, C. Ungermann
2002Journal of Cell Biology115 citations Open access
Semantic Scholar
Sec1/Munc18 protein Vps33 binds to SNARE domains and the quaternary SNARE complex
Braden T. Lobingier, Alexey J. Merz
2012Molecular Biology of the Cell113 citations Open access
Semantic Scholar
Traversal of a Polarized Epithelium by Pathogenic Neisseriae: Facilitation by Type IV Pili and Maintenance of Epithelial Barrier Function
Alexey J. Merz, D. Rifenbery, C. Arvidson, Magdalene So
1996Molecular Medicine113 citations Open access
Semantic Scholar
A soluble SNARE drives rapid docking, bypassing ATP and Sec17/18p for vacuole fusion
Naomi Thorngren, Kevin M. Collins, Rutilio A. Fratti, W. Wickner +1 more
2004EMBO Journal108 citations Open access
Semantic Scholar
Capture and release of partially zipped trans-SNARE complexes on intact organelles
Matthew L. Schwartz, Alexey J. Merz
2009Journal of Cell Biology106 citations Open access
Semantic Scholar
Trans-SNARE interactions elicit Ca2+ efflux from the yeast vacuole lumen
Alexey J. Merz, W. Wickner
2004Journal of Cell Biology95 citations Open access
Semantic Scholar
Hallmarks of Reversible Separation of Living, Unperturbed Cell Membranes into Two Liquid Phases.
Scott P. Rayermann, Glennis E. Rayermann, C. Cornell, Alexey J. Merz +1 more
2017Biophysical Journal92 citations Open access
Semantic Scholar
Tissue-specific autophagy responses to aging and stress in C. elegans
Hannah C. Chapin, Megan Okada, Alexey J. Merz, Dana L. Miller
2015Aging88 citations Open access
Semantic Scholar
HOPS interacts with Apl5 at the vacuole membrane and is required for consumption of AP-3 transport vesicles.
C. Angers, Alexey J. Merz
2009Molecular Biology of the Cell83 citations Open access
Semantic Scholar
Bacterial surface motility: slime trails, grappling hooks and nozzles.
Alexey J. Merz, K. Forest
2002Current Biology81 citations Open access
Semantic Scholar
New links between vesicle coats and Rab-mediated vesicle targeting
C. Angers, Alexey J. Merz
2010Seminars in Cell and Developmental Biology74 citations Open access
Semantic Scholar
SM proteins Sly1 and Vps33 co-assemble with Sec17 and SNARE complexes to oppose SNARE disassembly by Sec18
Braden T. Lobingier, D. Nickerson, Sheng-Ying Lo, Alexey J. Merz
2014eLife70 citations Open access
Semantic Scholar
A phosphatidylinositol 3-kinase effector alters phagosomal maturation to promote intracellular growth of Francisella
Hannah E. Ledvina, Katherine A. Kelly, A. Eshraghi, Rachael L. Plemel +9 more
2018Cell Host and Microbe63 citations Open access
Semantic Scholar
Sec17 can trigger fusion of trans-SNARE paired membranes without Sec18
Michael Zick, Amy S. Orr, Matthew L. Schwartz, Alexey J. Merz +1 more
2015Proceedings of the National Academy of Sciences of the United States of America59 citations Open access
Semantic Scholar
Intrinsic tethering activity of endosomal Rab proteins
Sheng-Ying Lo, C. L. Brett, Rachael L. Plemel, M. Vignali +3 more
2011Nature Structural &Molecular Biology58 citations Open access
Semantic Scholar
Osmotic regulation of Rab-mediated organelle docking
C. L. Brett, Alexey J. Merz
2008Current Biology51 citations Open access
Semantic Scholar
Sec17/Sec18 act twice, enhancing membrane fusion and then disassembling cis-SNARE complexes
Hongki Song, Amy S. Orr, M. Duan, Alexey J. Merz +1 more
2017eLife49 citations Open access
Semantic Scholar
Resolution of organelle docking and fusion kinetics in a cell-free assay.
Alexey J. Merz, W. Wickner
2004Proceedings of the National Academy of Sciences of the United States of America45 citations Open access
Semantic Scholar
Sec17 (α-SNAP) and an SM-tethering complex regulate the outcome of SNARE zippering in vitro and in vivo
Matthew L. Schwartz, D. Nickerson, Braden T. Lobingier, Rachael L. Plemel +4 more
2017eLife44 citations Open access
Semantic Scholar
Vps9 Family Protein Muk1 Is the Second Rab5 Guanosine Nucleotide Exchange Factor in Budding Yeast*
Andrew Paulsel, Alexey J. Merz, D. Nickerson
2013Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Rho Signaling Participates in Membrane Fluidity Homeostasis
D. Lockshon, C. Olsen, C. L. Brett, Andrei O. Chertov +4 more
2012PLoS ONE39 citations Open access
Semantic Scholar
Yeast cells actively tune their membranes to phase separate at temperatures that scale with growth temperatures
Chantelle L. Leveille, C. Cornell, Alexey J. Merz, S. Keller
2021Proceedings of the National Academy of Sciences of the United States of America38 citations Open access
Semantic Scholar
The Prototypical H+/Galactose Symporter GalP Assembles into Functional Trimers
Hong-Jin Zheng, Justin W. Taraska, Alexey J. Merz, T. Gonen
2009Journal of Molecular Biology33 citations Open access
Semantic Scholar
Aneuploidy shortens replicative lifespan in Saccharomyces cerevisiae
Anna B Sunshine, Giang T. Ong, D. Nickerson, Daniel T. Carr +6 more
2016Aging Cell30 citations Open access
Semantic Scholar
Ubiquitin binding by the CUE domain promotes endosomal localization of the Rab5 GEF Vps9
Tess Shideler, D. Nickerson, Alexey J. Merz, Greg Odorizzi
2015Molecular Biology of the Cell26 citations Open access
Semantic Scholar
Clathrin functions in the absence of the terminal domain binding site for adaptor-associated clathrin-box motifs.
John R. Collette, R. Chi, Douglas R. Boettner, I. Fernández-Golbano +5 more
2009Molecular Biology of the Cell25 citations Open access
Semantic Scholar
Remodeling of yeast vacuole membrane lipidomes from the log (1-phase) to stationary stage (2-phases)
J. Reinhard, Chantelle L. Leveille, C. Cornell, Alexey J. Merz +3 more
2022bioRxiv20 citations Open access
Semantic Scholar
The Dense-Core Vesicle Maturation Protein CCCP-1 Binds RAB-2 and Membranes through its C-terminal Domain
Jérôme Cattin-Ortolá, Irini Topalidou, Annie M. Dosey, Alexey J. Merz +1 more
2017bioRxiv16 citations Open access
Semantic Scholar
What are the roles of V-ATPases in membrane fusion?
Alexey J. Merz
2014Proceedings of the National Academy of Sciences of the United States of America16 citations Open access
Semantic Scholar
Listeria motility: biophysics pushes things forward.
Alexey J. Merz, Henry N. Higgs
2003Current Biology15 citations Open access
Semantic Scholar
Organelle and proteome quality control mechanisms: how cells are able to keep calm and carry on
J. Brodsky, Alexey J. Merz, T. Serio
2014Molecular Biology of the Cell5 citations Open access
Semantic Scholar
Genetically encoded multimode reporter of adaptor protein 3 (AP-3) traffic in budding yeast
Rachael L. Plemel, Greg Odorizzi, Alexey J. Merz
2020Traffic : the International Journal of Intracellular Transport2 citations Open access
Semantic Scholar
Hallmarks of Reversible Phase Separation in Living, Unperturbed Cell Membranes
Scott P. Rayermann, Glennis E. Rayermann, Alexey J. Merz, S. Keller
20172 citations Open access
Semantic Scholar
Reversible, large-scale, liquid-liquid phase separation in living yeast membranes.
S. Keller, Chantelle L. Leveille, J. Reinhard, C. Cornell +5 more
2023Biophysical Journal1 citations Open access
Semantic Scholar
Decision letter: Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt
Alexey J. Merz, C. Ungermann
20191 citations Open access
Semantic Scholar
Sec17 (α-SNAP) and an SM-tethering complex control the outcome of SNARE zippering in vitro and in vivo
Matthew L. Schwartz, D. Nickerson, Braden T. Lobingier, C. Angers +2 more
2017bioRxiv1 citations Open access
Semantic Scholar
BPS2026 – Temperature at which yeast vacuole membranes undergo liquid-liquid phase separation as a function of time in the stationary stage (Tmix vs time)
Sena Noaman, Alexey J. Merz, Sarah L. Keller
2026Biophysical Journal0 citations
Semantic Scholar
Abstract 1504: Septin filaments interact with AP-3 and are required for trafficking via the AP-3 pathway in budding yeast
Mitchell Leih, Madeline Cohen, E. Conibear, Alexey J. Merz +1 more
2023Journal of Biological Chemistry0 citations Open access
Semantic Scholar
Yeast cells actively tune their membranes to phase separate at temperatures that scale linearly with growth temperatures
Chantelle L. Leveille, C. Cornell, Alexey J. Merz, S. Keller
2022Biophysical Journal0 citations Open access
Semantic Scholar
Decision letter: Fusion of tethered membranes can be driven by Sec18/NSF and Sec17/αSNAP without HOPS
Alexey J. Merz
20210 citations Open access
Semantic Scholar
Author response for "Genetically encoded multimode reporter of AP ‐3 traffic in budding yeast"
Rachael L. Plemel, Greg Odorizzi, Alexey J. Merz
20200 citations
Semantic Scholar
Genetically encoded multimode reporter of adaptor protein 3 (AP-3) traffic in budding yeast
Rachael L. Plemel, Greg Odorizzi, Alexey J. Merz
20200 citations
Semantic Scholar

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Rachael L. Plemel×10
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Rachael L. Plemel — researcher profile on SciRah
D. Nickerson×8
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W. Wickner×8
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C. L. Brett×6
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C. L. Brett — researcher profile on SciRah

Braden T. Lobingier

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Matthew L. Schwartz×4

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Chantelle L. Leveille×4

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Chantelle L. Leveille — researcher profile on SciRah

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Scott P. Rayermann — researcher profile on SciRah