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Clayton P. Santiago · SciRah

Researcher profile · Semantic Scholar

Clayton P. Santiago

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Clayton P. Santiago — researcher profile on SciRah

h-index: 11
Works: 34
Citations: 1,153

Most-cited papers

Single cell RNA-Seq analysis of retinal development identifies NFI factors as regulating mitotic exit and late-born cell specification.
Brian S. Clark, G. Stein-O'Brien, Fion Shiau, Gabrielle H. Cannon +10 more
2019Neuron409 citations Open access
Semantic Scholar
Gene regulatory networks controlling vertebrate retinal regeneration
Thanh V. Hoang, Jie Wang, Patrick Boyd, F. Wang +22 more
2020Science342 citations Open access
Semantic Scholar
Gene regulatory networks controlling temporal patterning, neurogenesis, and cell-fate specification in mammalian retina
Pin Lyu, Thanh V. Hoang, Clayton P. Santiago, E. Thomas +14 more
2021bioRxiv104 citations Open access
Semantic Scholar
ASCOT identifies key regulators of neuronal subtype-specific splicing
Jonathan P. Ling, C. Wilks, Rone Charles, Patrick J. Leavey +9 more
2018Nature Communications79 citations Open access
Semantic Scholar
Transcriptomic Profiling of Control and Thyroid-Associated Orbitopathy (TAO) Orbital Fat and TAO Orbital Fibroblasts Undergoing Adipogenesis
D. W. Kim, Kamil Taneja, Thanh V. Hoang, Clayton P. Santiago +5 more
2021Investigative Ophthalmology and Visual Science37 citations Open access
Semantic Scholar
C5a Activates a Pro-Inflammatory Gene Expression Profile in Human Gaucher iPSC-Derived Macrophages
Jacquelyn C Serfecz, Afsoon Saadin, Clayton P. Santiago, Yu-Ji Zhang +3 more
2021International Journal of Molecular Sciences35 citations Open access
Semantic Scholar
A drug-tunable gene therapy for broad-spectrum protection against retinal degeneration
Clayton P. Santiago, C. Keuthan, Sanford L. Boye, Shannon E. Boye +2 more
2018bioRxiv31 citations Open access
Semantic Scholar
Single-cell transcriptome analysis of xenotransplanted human retinal organoids defines two migratory cell populations of nonretinal origin
Ying V. Liu, Clayton P. Santiago, Akin Sogunro, Gregory Konar +19 more
2023Stem Cell Reports25 citations Open access
Semantic Scholar
Comparative transcriptomic and epigenomic analysis identifies key regulators of injury response and neurogenic competence in retinal glia
Thanh V. Hoang, Jie Wang, Patrick Boyd, Fang Wang +21 more
2019bioRxiv21 citations Open access
Semantic Scholar
Comparative Analysis of Single-cell and Single-nucleus RNA-sequencing in a Rabbit Model of Retinal Detachment-related Proliferative Vitreoretinopathy
Clayton P. Santiago, Megan Y. Gimmen, Yuchen Lu, Minda M. McNally +5 more
2022bioRxiv19 citations Open access
Semantic Scholar
Cell-specific regulation of gene expression using splicing-dependent frameshifting
Jonathan P. Ling, Alexei M. Bygrave, Clayton P. Santiago, Rogger P. Carmen-Orozco +32 more
2022bioRxiv18 citations Open access
Semantic Scholar
Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis
Xiao-Dong Li, Patrick J Gordon, John A. Gaynes, Alexandra W. Fuller +6 more
2021bioRxiv10 citations Open access
Semantic Scholar
Retinal homeostasis and metformin-induced protection are not affected by retina-specific Pparδ knockout
Lei Xu, Emily E. Brown, Clayton P. Santiago, C. Keuthan +2 more
2020Redox Biology7 citations Open access
Semantic Scholar
Multiplexed Analysis of Retinal Gene Expression and Chromatin Accessibility using scRNA-Seq and scATAC-Seq
Kurt Weir, P. Leavey, Clayton P. Santiago, S. Blackshaw
2021Journal of Visualized Experiments5 citations Open access
Semantic Scholar
Self-transmissible IncP R995 plasmids with alternative markers and utility for Flp/FRT cloning strategies.
Clayton P. Santiago, L. Quick, James W. Wilson
2011Journal of Microbiology and Biotechnology5 citations
Semantic Scholar
Transfer of the cloned Salmonella SPI-1 type III secretion system and characterization of its expression mechanisms in Gram negative bacteria in comparison with cloned SPI-2.
C. Cangelosi, Susan E. Hannagan, Clayton P. Santiago, James W. Wilson
2015Microbiology Research4 citations Open access
Semantic Scholar
Recombineering and Conjugation as Tools for Targeted Genomic Cloning
James W. Wilson, Clayton P. Santiago, Jacquelyn C Serfecz, L. Quick
20133 citations Open access
Semantic Scholar
Evidence that Stat3 protects photoreceptors by increasing expression of protein editing genes and decreasing outer segment genes
C. Keuthan, Clayton P. Santiago, Marcus J. Hooper, L. Qian +1 more
20181 citations
Semantic Scholar
Engineering large functional plasmids for biosafety.
C. Cangelosi, Caroline Shank, Clayton P. Santiago, James W. Wilson
2013Plasmid1 citations
Semantic Scholar
Transretinal migration of astrocytes and brain/spinal cord-like cells arising from transplanted human retinal organoids
Ying V. Liu, Clayton P. Santiago, Akin Sogunro, Gregory Konar +15 more
2022bioRxiv0 citations Open access
Semantic Scholar
Cellular and Fibrillar Collagen Analyses in an Animal Model of Retinal Detachment-Related Proliferative Vitreoretinopathy Reveals a Defined Transition to Chronic Fibrosis
Cornelia Peterson, Clayton P. Santiago, Yuchen Lu, Antoinette C. Price +5 more
2022bioRxiv0 citations Open access
Semantic Scholar
Transcriptomic profiling of human orbital fat and differentiating orbital fibroblasts
D. W. Kim, Kamil Taneja, Thanh V. Hoang, Clayton P. Santiago +5 more
2021bioRxiv0 citations Open access
Semantic Scholar
Nuclear Factor I Regulates Proliferation and Specification of Müller glial and Bipolar Cells
Clayton P. Santiago, Thanh V. Hoang, D. Espinoza, Jie Wang +4 more
20190 citations
Semantic Scholar
Müller cell transcriptional unit to regulate stress induced LIF expression
Clayton P. Santiago, Marcus J. Hooper, Thanh V. Hoang, Jie Wang +3 more
20180 citations
Semantic Scholar
Development of a drug-regulated, broad-spectrum neuroprotective gene therapy for retinal degeneration
J. Ash, C. Keuthan, A. A. Imam, Sanford L. Boye +2 more
20180 citations
Semantic Scholar
STAT3 directly regulates stress-induced expression of Edn2, to promote protection of photoreceptors through the activation of EdnrA
Marcus J. Hooper, Clayton P. Santiago, J. Ash
20180 citations
Semantic Scholar
Transcriptomics analysis of Muller glia in response to different damage paradigms in the adult zebrafish retina
D. Hyde, Patrick Boyd, M. Lahne, Thanh V. Hoang +6 more
20180 citations
Semantic Scholar
Comparative transcriptomic and epigenomic analysis identifes regulators of neurogenic competence in retinal Müller glia.
S. Blackshaw, Thanh V. Hoang, Jie Wang, M. Lahne +8 more
20180 citations
Semantic Scholar
Toll-like receptor 2 promotes photoreceptor survival in acute retinal injury
Marcus J. Hooper, Clayton P. Santiago, R. Ramchander, J. Ash
20170 citations
Semantic Scholar
Using RiboTag and Sun1-sfGFP technologies to map Müller cell-specific epigenetic regulation of stress-induced LIF expression in vivo.
Clayton P. Santiago, C. Keuthan, A. A. Imam, J. Ash
20170 citations
Semantic Scholar
Epigenetic regulation of stress-induced LIF expression.
Clayton P. Santiago, J. Ash
20160 citations
Semantic Scholar
Expression of the neuroprotective cytokine, Leukemia Inhibitory Factor, is potentially regulated by elements in its 3’untranslated region
Clayton P. Santiago, J. Ash
20150 citations
Semantic Scholar
United States Patent Nagrath
Deepak Nagrath, Marco Avila-Elchiver, Clayton P. Santiago, M. Yarmush
20130 citations
Semantic Scholar
Characterization of the activity of the cloned SPI-2 type III secretion system in Salmonella Typhimurium
Clayton P. Santiago
20120 citations
Semantic Scholar

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