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M. Federico · SciRah

Researcher profile · Semantic Scholar

M. Federico

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M. Federico — researcher profile on SciRah

h-index: 33
Works: 146
Citations: 3,847

Most-cited papers

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
George B. Kyei, Christina Dinkins, Alexander S. Davis, Esteban A. Roberts +10 more
2009Journal of Cell Biology510 citations Open access
Semantic Scholar
Exosomes from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Cells License Quiescent CD4+ T Lymphocytes To Replicate HIV-1 through a Nef- and ADAM17-Dependent Mechanism
Claudia Arenaccio, C. Chiozzini, Sandra Columba-cabezas, F. Manfredi +3 more
2014Journal of Virology169 citations Open access
Semantic Scholar
Massive secretion by T cells is caused by HIV Nef in infected cells and by Nef transfer to bystander cells.
C. Muratori, L. Cavallin, K. Krätzel, A. Tinari +9 more
2009Cell Host and Microbe162 citations Open access
Semantic Scholar
HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases.
Jung-Hyun Lee, Sebastian Wittki, Tanja Bräu, Florian S. Dreyer +13 more
2013Molecules and Cells110 citations Open access
Semantic Scholar
An Exosome-Based Vaccine Platform Imparts Cytotoxic T Lymphocyte Immunity Against Viral Antigens.
S. Anticoli, F. Manfredi, C. Chiozzini, Claudia Arenaccio +6 more
2018Biotechnology Journal91 citations
Semantic Scholar
Latent HIV-1 is activated by exosomes from cells infected with either replication-competent or defective HIV-1
Claudia Arenaccio, S. Anticoli, F. Manfredi, C. Chiozzini +2 more
2015Retrovirology87 citations Open access
Semantic Scholar
Human papillomavirus E6 and E7 oncoproteins affect the expression of cancer-related microRNAs: additional evidence in HPV-induced tumorigenesis
M. V. Chiantore, Giorgio Mangino, Marco Iuliano, Marianna Zangrillo +8 more
2016Journal of Cancer Research and Clinical Oncology80 citations Open access
Semantic Scholar
A strategy of antigen incorporation into exosomes: comparing cross-presentation levels of antigens delivered by engineered exosomes and by lentiviral virus-like particles.
L. Lattanzi, M. Federico
2012Vaccine74 citations
Semantic Scholar
HIV-1 Nef protects human-monocyte-derived macrophages from HIV-1-induced apoptosis.
E. Olivetta, M. Federico
2006Experimental Cell Research65 citations
Semantic Scholar
Sequences within RNA coding for HIV‐1 Gag p17 are efficiently targeted to exosomes
Sandra Columba Cabezas, M. Federico
2013Cellular Microbiology63 citations Open access
Semantic Scholar
In Vitro Treatment of Human Monocytes/Macrophages with Myristoylated Recombinant Nef of Human Immunodeficiency Virus Type 1 Leads to the Activation of Mitogen-Activated Protein Kinases, IκB Kinases, and Interferon Regulatory Factor 3 and to the Release of Beta Interferon
Giorgio Mangino, Z. Percario, G. Fiorucci, G. Vaccari +5 more
2006Journal of Virology61 citations Open access
Semantic Scholar
HIV-1 Nef regulates the release of superoxide anions from human macrophages.
E. Olivetta, D. Pietraforte, Ilaria Schiavoni, M. Minetti +2 more
2005Biochemical Journal61 citations Open access
Semantic Scholar
Cell activation and HIV-1 replication in unstimulated CD4+ T lymphocytes ingesting exosomes from cells expressing defective HIV-1
Claudia Arenaccio, C. Chiozzini, Sandra Columba-cabezas, F. Manfredi +1 more
2014Retrovirology59 citations Open access
Semantic Scholar
Antitumor HPV E7-specific CTL activity elicited by in vivo engineered exosomes produced through DNA inoculation
P. Di Bonito, C. Chiozzini, Claudia Arenaccio, S. Anticoli +6 more
2017International Journal of Nanomedicine58 citations Open access
Semantic Scholar
HIV-1 Tat Promotes Integrin-Mediated HIV Transmission to Dendritic Cells by Binding Env Spikes and Competes Neutralization by Anti-HIV Antibodies
P. Monini, A. Cafaro, I. Srivastava, S. Moretti +40 more
2012PLoS ONE56 citations Open access
Semantic Scholar
HPV-E7 Delivered by Engineered Exosomes Elicits a Protective CD8+ T Cell-Mediated Immune Response
P. Di Bonito, B. Ridolfi, Sandra Columba-cabezas, A. Giovannelli +5 more
2015Viruses55 citations Open access
Semantic Scholar
The Multifaceted Functions of Exosomes in Health and Disease: An Overview.
Claudia Arenaccio, M. Federico
2017Advances in Experimental Medicine and Biology52 citations
Semantic Scholar
Perturbed replication induced genome wide or at common fragile sites is differently managed in the absence of WRN.
Ivana Murfuni, A. De Santis, M. Federico, M. Bignami +2 more
2012Carcinogenesis47 citations Open access
Semantic Scholar
Exosomes in Therapy: Engineering, Pharmacokinetics and Future Applications.
Claudia Arenaccio, C. Chiozzini, F. Ferrantelli, P. Leone +2 more
2018Current Drug Targets43 citations
Semantic Scholar
Anti-tumor CD8+ T cell immunity elicited by HIV-1-based virus-like particles incorporating HPV-16 E7 protein.
P. Di Bonito, F. Grasso, S. Mochi, L. Petrone +14 more
2009Virology43 citations Open access
Semantic Scholar
Cell death induced by the herpes simplex virus-1 thymidine kinase delivered by human immunodeficiency virus-1-based virus-like particles.
S. Peretti, Ilaria Schiavoni, K. Pugliese, M. Federico
2005Molecular Therapy40 citations Open access
Semantic Scholar
Virological Consequences of Early Events following Cell-Cell Contact between Human Immunodeficiency Virus Type 1-Infected and Uninfected CD4+ Cells
E. Ruggiero, R. Bona, C. Muratori, M. Federico
2008Journal of Virology39 citations Open access
Semantic Scholar
DNA Vectors Generating Engineered Exosomes Potential CTL Vaccine Candidates Against AIDS, Hepatitis B, and Tumors
F. Ferrantelli, F. Manfredi, C. Chiozzini, S. Anticoli +3 more
2018Molecular Biotechnology36 citations
Semantic Scholar
Astrocytes contacting HIV‐1‐infected macrophages increase the release of CCL2 in response to the HIV‐1‐dependent enhancement of membrane‐associated TNFα in macrophages
C. Muratori, Giorgio Mangino, E. Affabris, M. Federico
2010Glia35 citations
Semantic Scholar
Anti-Cancer Vaccine for HPV-Associated Neoplasms: Focus on a Therapeutic HPV Vaccine Based on a Novel Tumor Antigen Delivery Method Using Endogenously Engineered Exosomes
P. Di Bonito, L. Accardi, Luisa Galati, F. Ferrantelli +1 more
2019Cancers34 citations Open access
Semantic Scholar
Engineered exosomes emerging from muscle cells break immune tolerance to HER2 in transgenic mice and induce antigen-specific CTLs upon challenge by human dendritic cells
S. Anticoli, E. Aricò, Claudia Arenaccio, F. Manfredi +7 more
2018Journal of molecular medicine31 citations
Semantic Scholar
Erratum to: Endogenous CCL2 neutralization restricts HIV-1 replication in primary human macrophages by inhibiting viral DNA accumulation
Michela Sabbatucci, D. Covino, C. Purificato, A. Mallano +11 more
2015Retrovirology31 citations Open access
Semantic Scholar
miR-146a controls CXCR4 expression in a pathway that involves PLZF and can be used to inhibit HIV-1 infection of CD4(+) T lymphocytes.
M. T. Quaranta, E. Olivetta, Massimo Sanchez, I. Spinello +4 more
2015Virology31 citations Open access
Semantic Scholar
Lentivirus-based virus-like particles as a new protein delivery tool.
C. Muratori, R. Bona, M. Federico
2010Methods in molecular biology30 citations
Semantic Scholar
HIV‐1 Nef induces p47phox phosphorylation leading to a rapid superoxide anion release from the U937 human monoblastic cell line
E. Olivetta, C. Mallozzi, V. Ruggieri, D. Pietraforte +2 more
2009Journal of Cellular Biochemistry27 citations
Semantic Scholar
Exploiting Manipulated Small Extracellular Vesicles to Subvert Immunosuppression at the Tumor Microenvironment through Mannose Receptor/CD206 Targeting
M. Fiani, Valeria Barreca, M. Sargiacomo, F. Ferrantelli +2 more
2020International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
The Intracellular Delivery Of Anti-HPV16 E7 scFvs Through Engineered Extracellular Vesicles Inhibits The Proliferation Of HPV-Infected Cells
F. Ferrantelli, Claudia Arenaccio, F. Manfredi, E. Olivetta +8 more
2019International Journal of Nanomedicine23 citations Open access
Semantic Scholar
Selective elimination of HIV-1-infected cells by Env-directed, HIV-1-based virus-like particles.
S. Peretti, Ilaria Schiavoni, K. Pugliese, M. Federico
2006Virology22 citations Open access
Semantic Scholar
Strong SARS-CoV-2 N-Specific CD8+ T Immunity Induced by Engineered Extracellular Vesicles Associates with Protection from Lethal Infection in Mice
F. Ferrantelli, C. Chiozzini, F. Manfredi, P. Leone +7 more
2022bioRxiv21 citations Open access
Semantic Scholar
Macrophages Transmit Human Immunodeficiency Virus Type 1 Products to CD4-Negative Cells: Involvement of Matrix Metalloproteinase 9
C. Muratori, A. Sistigu, E. Ruggiero, M. Falchi +4 more
2007Journal of Virology21 citations Open access
Semantic Scholar
T Lymphocytes transduced with a lentiviral vector expressing F12-Vif are protected from HIV-1 infection in an APOBEC3G-independent manner.
G. Vallanti, R. Lupo, M. Federico, F. Mavilio +1 more
2005Molecular Therapy21 citations Open access
Semantic Scholar
Simultaneous CD8+ T-Cell Immune Response against SARS-Cov-2 S, M, and N Induced by Endogenously Engineered Extracellular Vesicles in Both Spleen and Lungs
F. Ferrantelli, C. Chiozzini, F. Manfredi, A. Giovannelli +2 more
2021Vaccines20 citations Open access
Semantic Scholar
Incorporation of Heterologous Proteins in Engineered Exosomes.
F. Manfredi, P. Di Bonito, Claudia Arenaccio, S. Anticoli +1 more
2016Methods in molecular biology20 citations
Semantic Scholar
Development of a novel human phage display-derived anti-LAG3 scFv antibody targeting CD8+ T lymphocyte exhaustion
A. Ascione, Claudia Arenaccio, A. Mallano, M. Flego +6 more
2019BMC Biotechnology18 citations Open access
Semantic Scholar
The CD8+ T Cell-Mediated Immunity Induced by HPV-E6 Uploaded in Engineered Exosomes Is Improved by ISCOMATRIXTM Adjuvant
F. Manfredi, P. Di Bonito, B. Ridolfi, S. Anticoli +4 more
2016Vaccines18 citations Open access
Semantic Scholar
Lentiviral Vectors and Exosomes as Gene and Protein Delivery Tools
M. Federico
2016Methods in Molecular Biology17 citations
Semantic Scholar
The Contribution of Extracellular Nef to HIV-Induced Pathogenesis.
E. Olivetta, Claudia Arenaccio, F. Manfredi, S. Anticoli +1 more
2015Current Drug Targets17 citations
Semantic Scholar
Generation and characterization of a stable cell population releasing fluorescent HIV-1-based Virus Like Particles in an inducible way
C. Muratori, P. D'Aloja, F. Superti, A. Tinari +5 more
2006BMC Biotechnology17 citations Open access
Semantic Scholar
Engineered Extracellular Vesicles/Exosomes as a New Tool against Neurodegenerative Diseases
F. Ferrantelli, C. Chiozzini, P. Leone, F. Manfredi +1 more
2020Pharmaceutics15 citations Open access
Semantic Scholar
The ADAR1 editing enzyme is encapsidated into HIV-1 virions.
Elisa Orecchini, M. Federico, M. Doria, Claudia Arenaccio +3 more
2015Virology15 citations Open access
Semantic Scholar
Endogenous CCL2 neutralization restricts HIV-1 replication in primary human macrophages by inhibiting viral DNA accumulation
Michela Sabbatucci, D. Covino, C. Purificato, A. Mallano +11 more
2015Retrovirology15 citations Open access
Semantic Scholar
N-Terminal Fatty Acids of NEFMUT Are Required for the CD8+ T-Cell Immunogenicity of In Vivo Engineered Extracellular Vesicles
C. Chiozzini, F. Manfredi, Claudia Arenaccio, F. Ferrantelli +2 more
2020Vaccines14 citations Open access
Semantic Scholar
Engineered exosomes boost the HCV NS3-specific CD8+ T lymphocyte immunity in humans
S. Anticoli, E. Falcone, A. Ruggieri, M. Federico
201614 citations Open access
Semantic Scholar
Surface-bound Tat inhibits antigen-specific CD8+ T-cell activation in an integrin-dependent manner
C. Chiozzini, B. Collacchi, F. Nappi, T. Bauer +7 more
2014AIDS (London)14 citations Open access
Semantic Scholar
Trans-dissemination of exosomes from HIV-1-infected cells fosters both HIV-1 trans-infection in resting CD4+ T lymphocytes and reactivation of the HIV-1 reservoir
C. Chiozzini, Claudia Arenaccio, E. Olivetta, S. Anticoli +6 more
2017Archives of Virology13 citations
Semantic Scholar

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