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O. Luo · SciRah

Researcher profile · Semantic Scholar

O. Luo

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O. Luo — researcher profile on SciRah

h-index: 18
Works: 70
Citations: 8,344

Most-cited papers

Landscape of transcription in human cells
S. Djebali, Carrie A. Davis, A. Merkel, A. Dobin +81 more
2012Nature5,000 citations Open access
Semantic Scholar
CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription
Zhonghui Tang, O. Luo, Xing-Wang Li, Meizhen Zheng +20 more
2015Cell929 citations Open access
Semantic Scholar
The draft genome of sweet orange (Citrus sinensis)
Qiang Xu, Ling-Ling Chen, Xiaoan Ruan, Di-Jun Chen +35 more
2012Nature Genetics924 citations Open access
Semantic Scholar
Biomarkers of aging
Hai-Mei Bao, Jia-Ni Cao, Meng-Ting Chen, Min Chen +120 more
2023Science China Life Sciences298 citations Open access
Semantic Scholar
Transcriptional profiles of bovine in vivo pre-implantation development
Z. Jiang, Jiang-Wen Sun, Hong Dong, O. Luo +8 more
2014BMC Genomics179 citations Open access
Semantic Scholar
Multidimensional single-cell analysis of human peripheral blood reveals characteristic features of the immune system landscape in aging and frailty
O. Luo, Wen Lei, Guo-Dong Zhu, Zhi-Yao Ren +22 more
2022Nature Aging141 citations
Semantic Scholar
Long-read ChIA-PET for base-pair resolution mapping of haplotype-specific chromatin interactions
Xing-Wang Li, O. Luo, Ping Wang, Meizhen Zheng +7 more
2017Nature Protocols115 citations Open access
Semantic Scholar
Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs
I. Ricaño-Ponce, D. Zhernakova, Patrick Deelen, O. Luo +62 more
2016Journal of Autoimmunity74 citations Open access
Semantic Scholar
Multiomic Profiling Identifies cis-Regulatory Networks Underlying Human Pancreatic β Cell Identity and Function
Nathan Lawlor, E. Márquez, P. Orchard, N. Narisu +23 more
2019Cell Reports70 citations Open access
Semantic Scholar
An integrated 3-Dimensional Genome Modeling Engine for data-driven simulation of spatial genome organization
Przemyslaw Szalaj, Zhonghui Tang, Paul J. Michalski, Michal J. Pietal +6 more
2016Genome Research49 citations Open access
Semantic Scholar
Insufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults
Chan-Chan Xiao, Zhi-Yao Ren, Bei Zhang, Li-Peng Mao +24 more
2023Nature Aging43 citations Open access
Semantic Scholar
Immune-Ageing Evaluation of Peripheral T and NK Lymphocyte Subsets in Chinese Healthy Adults
Zheng-Hu Jia, Zhi-Yao Ren, D. Ye, Jia-Wei Li +22 more
2023Phenomics34 citations Open access
Semantic Scholar
Lipid-associated macrophages for osimertinib resistance and leptomeningeal metastases in NSCLC.
Yang-Si Li, W. Lai, Kai Yin, M. Zheng +26 more
2024Cell Reports32 citations Open access
Semantic Scholar
Immunological risk factors for sepsis-associated delirium and mortality in ICU patients
Wen Lei, Zhi-Yao Ren, Jun Su, Xing-Long Zheng +12 more
2022Frontiers in Immunology28 citations Open access
Semantic Scholar
Identification and validation of predictive factors for progression to severe COVID-19 pneumonia by proteomics
B. Di, Hong-Ling Jia, O. Luo, Fangqin Lin +6 more
2020Signal Transduction and Targeted Therapy24 citations Open access
Semantic Scholar
Intra- and inter-individual genetic differences in gene expression
M. Cowley, C. Cotsapas, Rohan Williams, E. Chan +5 more
2008Mammalian Genome24 citations Open access
Semantic Scholar
Global analysis of HLA-A2 restricted MAGE-A3 tumor antigen epitopes and corresponding TCRs in non-small cell lung cancer
Bei Zhang, Zhi-Yao Ren, Jian-Fu Zhao, Yue Zhu +11 more
2023Theranostics21 citations Open access
Semantic Scholar
CD8+ T-Cell Epitope Variations Suggest a Potential Antigen HLA-A2 Binding Deficiency for Spike Protein of SARS-CoV-2
Congling Qiu, Chan-Chan Xiao, Zhi-Gang Wang, Guo-Dong Zhu +15 more
2022Frontiers in Immunology21 citations Open access
Semantic Scholar
RNA-Targeting CRISPR/CasRx system relieves disease symptoms in Huntington’s disease models
Ying-Qi Lin, Cai-Juan Li, Yi-Zhi Chen, Jia-Le Gao +14 more
2025Molecular Neurodegeneration19 citations Open access
Semantic Scholar
NAD+ reverses Alzheimer’s neurological deficits via regulating differential alternative RNA splicing of EVA1C
Ruixue Ai, Li-Peng Mao, Xurui Jin, Carlos Campos-Marques +29 more
2025Science Advances18 citations Open access
Semantic Scholar
An in-depth understanding of the role and mechanisms of T cells in immune organ aging and age-related diseases
Yudai Xu, Zi-Jian Wang, Shumin Li, Jun Su +6 more
2024Science China Life Sciences18 citations
Semantic Scholar
Macrophage mediated recognition and clearance of Borrelia burgdorferi elicits MyD88-dependent and -independent phagosomal signals that contribute to phagocytosis and inflammation
Sarah J. Benjamin, K. Hawley, P. Vera-Licona, Carson J. La Vake +7 more
2019bioRxiv18 citations Open access
Semantic Scholar
Identification of HLA-A2 restricted CD8+ T cell epitopes in SARS-CoV-2 structural proteins
Jie-Ping Deng, Jun-Ping Pan, Minghui Qiu, Li-Peng Mao +8 more
2021Journal of Leukocyte Biology17 citations Open access
Semantic Scholar
Reduced ULK1 links impaired autophagy and mitophagy to Alzheimer’s disease pathology
Jun-Ping Pan, Ping-Jie Wang, Jian-Ying Zhang, Anne-Brita Knapskog +36 more
2026Nature Aging16 citations Open access
Semantic Scholar
Pericytes promote metastasis by regulating tumor local vascular tone and hemodynamics
Xiaobo Li, Sishan Yan, Xiaoyu Wu, Qun Miao +22 more
2025Nature Communications14 citations Open access
Semantic Scholar
Gene Expression Analysis Reveals Age and Ethnicity Signatures Between Young and Old Adults in Human PBMC
Yang Hu, Yudai Xu, Li-Peng Mao, Wen Lei +10 more
2021Frontiers in Aging14 citations Open access
Semantic Scholar
SARS-CoV-2 variant B.1.1.7 caused HLA-A2+ CD8+ T cell epitope mutations for impaired cellular immune response
Chan-Chan Xiao, Li-Peng Mao, Zhi-Gang Wang, Li-Juan Gao +14 more
2021bioRxiv14 citations Open access
Semantic Scholar
The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis
Shu-Qin Cao, J. I. Jiménez-Loygorri, Yun-Guang Qiu, You-Jung Kang +33 more
2026Advancement of science13 citations Open access
Semantic Scholar
Lycium barbarum glycopeptide ameliorates aging phenotypes and enhances cardiac metabolism by activating the PINK1/Parkin-mediated mitophagy pathway in D-galactose-induced mice.
Tianchan Peng, Jian Xiang, Yun Tian, Xiaogen Tang +5 more
2025Experimental Gerontology12 citations Open access
Semantic Scholar
BRD4 inhibitor reduces exhaustion and blocks terminal differentiation in CAR-T cells by modulating BATF and EGR1
Song-Nan Sui, Mengjun Zhong, Shuxin Zhong, Xueting Peng +5 more
2024Biomarker Research12 citations Open access
Semantic Scholar
Single-cell profiling of T cells uncovers a tissue-resident memory-like T-cell subset associated with bidirectional prognosis for B-cell acute lymphoblastic leukemia
Wen-FuThomas Lai, Xiao-Fang Wang, Lian Liu, Ling Xu +9 more
2022Frontiers in Immunology12 citations Open access
Semantic Scholar
VariantSpark: Cloud-based machine learning for association study of complex phenotype and large-scale genomic data
Arash Bayat, Piotr Szul, Aidan R. O'Brien, Rob Dunne +6 more
2020GigaScience12 citations Open access
Semantic Scholar
Deciphering Immunosenescence From Child to Frailty: Transcriptional Changes, Inflammation Dynamics, and Adaptive Immune Alterations
Wen-Pu Lai, Qiuyue Feng, Wen Lei, Chanchan Xiao +10 more
2025Aging Cell11 citations
Semantic Scholar
CRISPR activation screening in a mouse model for drivers of hepatocellular carcinoma growth and metastasis
Bei Zhang, Zhi-Yao Ren, Hongmei Zheng, Meilan Lin +3 more
2023iScience11 citations Open access
Semantic Scholar
Optimization of antigen-specific CD8+ T cell activation conditions for infectious diseases including COVID-19
Chan-Chan Xiao, Congling Qiu, Jie-Ping Deng, Jie-Zhou Ye +5 more
2021STAR Protocols10 citations Open access
Semantic Scholar
QuIN: A Web Server for Querying and Visualizing Chromatin Interaction Networks
Asa Thibodeau, E. Márquez, O. Luo, Y. Ruan +5 more
2016PLoS Comput. Biol.9 citations Open access
Semantic Scholar
Secreted Clusterin Inhibits Tumorigenesis by Modulating Tumor Cell and Macrophage in Human Meningioma.
Chao Ke, Bo-Ya Huang, Jian Xiang, Jinlian Liang +11 more
2024Neuro-Oncology8 citations
Semantic Scholar
MIST: An interpretable and flexible deep learning framework for single–T cell transcriptome and receptor analysis
Wen-Pu Lai, Yang-Qiu Li, O. Luo
2024bioRxiv8 citations
Semantic Scholar
Single-cell dissection reveals promotive role of ENO1 in leukemia stem cell self-renewal and chemoresistance in acute myeloid leukemia
Yun Tian, Jiafan Guo, Li-Peng Mao, Zhixi Chen +5 more
2024Stem cell research & therapeutics8 citations Open access
Semantic Scholar
Reconstitution of T cell‐mediated immunity by umbilical cord‐derived mesenchymal stem cells in ulcerative colitis
Xiao-Ying Luo, Jieping Deng, Xiaoke Jiang, J. Mi +21 more
2025Clinical and Translational Medicine7 citations Open access
Semantic Scholar
Single‐cell RNA sequencing gene signatures for classifying and scoring exhausted CD8+ T cells in B‐cell acute lymphoblastic leukaemia
Song-Nan Sui, Yun Tian, Xiao-Fang Wang, Cheng-Wu Zeng +2 more
2023Cell Proliferation7 citations Open access
Semantic Scholar
Loss of REST associated with Alzheimer's disease pathology is ameliorated by NAD+
M. J. Lagartos-Donate, Beatriz Escobar-Doncel, Shi-Qi Zhang, Jun-Ping Pan +18 more
2026Brain : a journal of neurology6 citations Open access
Semantic Scholar
Single-cell transcriptomic analysis reveals metastatic and immunosuppressive characteristics in meningioma brain-tumor interface
Bo-Ya Huang, Jinlian Liang, Xiaogen Tang, Yue Zhu +7 more
2025Journal of Translational Medicine6 citations Open access
Semantic Scholar
High percentage of bone marrow CD8+ tissue-resident-like memory T cells predicts inferior survival in patients with acute myeloid leukemia
Letong Cai, Wen-Pu Lai, Dan-Lin Yao, Yinfeng Gu +14 more
2024Blood Science5 citations Open access
Semantic Scholar
UFMylation maintains tumor suppressor pVHL stability by activating the deubiquitinase BAP1
Xiao Yang, Ya-Lei Wen, Shengying Qin, Yang Zhou +13 more
2025Science Advances4 citations Open access
Semantic Scholar
Deep learning-enabled multiphoton microscopy predicts colorectal cancer recurrence from routine FFPE specimens
Ya-Bing Yang, Chan-Chan Xiao, De-Hua Zou, Lu Wang +13 more
2025npj Digital Medicine4 citations Open access
Semantic Scholar
Single‐Cell Multiomics Reveals TCR Clonotype‐Specific Phenotype and Stemness Heterogeneity of T‐ALL Cells
Song-Nan Sui, Xiao-Lei Wei, Yue Zhu, Qiuyue Feng +11 more
2024Cell Proliferation4 citations Open access
Semantic Scholar
Human T cell development and aging: Remodeling throughout the lifespan
Li-Peng Mao, Qiuyue Feng, O. Luo, Guo-Bing Chen +1 more
2023Aging Research4 citations Open access
Semantic Scholar
CD8+ T cell epitope variations suggest a potential antigen presentation deficiency for spike protein of SARS-CoV-2
Cong-Ling Qiu, Chan-Chan Xiao, Zhi-Gang Wang, Xiong-Fei Chen +13 more
2020bioRxiv4 citations Open access
Semantic Scholar
Multiomic Proﬁling Identiﬁes cis -Regulatory Networks Underlying Human Pancreatic b Cell Identity and Function
Nathan Lawlor, Duygu Eladio J. Ma'rquez Peter Orchard, Ucar Stephen C.J, Michael L. Parker +28 more
4 citations
Semantic Scholar

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