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D. Hirsch · SciRah

Researcher profile · Semantic Scholar

D. Hirsch

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D. Hirsch — researcher profile on SciRah

h-index: 17
Works: 63
Citations: 1,394

Most-cited papers

Topography of cancer-associated immune cells in human solid tumors
Jakob Nikolas Kather, M. Suarez-Carmona, P. Charoentong, Cleo-Aron Weis +16 more
2018eLife243 citations Open access
Semantic Scholar
Genomic and evolutionary classification of lung cancer in never smokers
Tong-Wu Zhang, P. Joubert, N. Ansari-Pour, Wei Zhao +57 more
2021Nature Genetics212 citations Open access
Semantic Scholar
LGR5 positivity defines stem-like cells in colorectal cancer.
D. Hirsch, N. Barker, Nicole E. McNeil, Yue Hu +5 more
2014Carcinogenesis162 citations Open access
Semantic Scholar
Chromothripsis and focal copy number alterations determine poor outcome in malignant melanoma
D. Hirsch, R. Kemmerling, Sean Davis, J. Camps +3 more
2012Cancer Research104 citations Open access
Semantic Scholar
Cell therapy for lung disease
S. Geiger, D. Hirsch, F. Hermann
2017European Respiratory Review83 citations Open access
Semantic Scholar
Treatment of advanced gastrointestinal cancer with genetically modified autologous mesenchymal stem cells: Results from the phase 1/2 TREAT‐ME‐1 trial
Jobst Christian Einem, C. Guenther, H. Volk, G. Grütz +11 more
2019International Journal of Cancer62 citations Open access
Semantic Scholar
Preclinical analysis of human mesenchymal stem cells: tumor tropism and therapeutic efficiency of local HSV-TK suicide gene therapy in glioblastoma
L. Dührsen, Sophie Hartfuß, D. Hirsch, S. Geiger +7 more
2019OncoTarget35 citations Open access
Semantic Scholar
TP53 loss initiates chromosomal instability in fallopian tube epithelial cells
Daniel Bronder, A. Tighe, Darawalee Wangsa, D. Zong +13 more
2021Disease Models & Mechanisms31 citations Open access
Semantic Scholar
Molecular patterns in the evolution of serrated lesion of the colorectum
T. Gaiser, Sandra Meinhardt, D. Hirsch, J. Killian +9 more
2012International Journal of Cancer31 citations Open access
Semantic Scholar
A New Whole Genome Amplification Method for Studying Clonal Evolution Patterns in Malignant Colorectal Polyps
D. Hirsch, J. Camps, Sudhir Varma, R. Kemmerling +3 more
2012Genes, Chromosomes and Cancer28 citations Open access
Semantic Scholar
The evolution of single cell-derived colorectal cancer cell lines is dominated by the continued selection of tumor-specific genomic imbalances, despite random chromosomal instability
Darawalee Wangsa, Rüdiger Braun, M. Schiefer, E. Gertz +15 more
2018Carcinogenesis27 citations Open access
Semantic Scholar
Molecular characterization of ulcerative colitis-associated colorectal carcinomas
D. Hirsch, J. Hardt, C. Sauer, Kerstin Heselmeyer-Hadded +4 more
2020Modern Pathology25 citations Open access
Semantic Scholar
Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies
Sushant Patkar, K. Heselmeyer-Haddad, Noam Auslander, D. Hirsch +21 more
2021Genome Medicine24 citations Open access
Semantic Scholar
Dynamics of Genome Alterations in Crohn’s Disease-Associated Colorectal Carcinogenesis
D. Hirsch, Darawalee Wangsa, Y. Zhu, Yue Hu +9 more
2018Clinical Cancer Research24 citations Open access
Semantic Scholar
Visualisation of HER2 homodimers in single cells from HER2 overexpressing primary formalin fixed paraffin embedded tumour tissue
D. Peckys, D. Hirsch, T. Gaiser, N. de Jonge
2019Molecular Medicine23 citations Open access
Semantic Scholar
Tetraploidy-Associated Genetic Heterogeneity Confers Chemo-Radiotherapy Resistance to Colorectal Cancer Cells
Claudia Galofré, Öykü Gönül Geyik, E. Asensio, Darawalee Wangsa +8 more
2020Cancers22 citations Open access
Semantic Scholar
Single-cell genetic analysis of clonal dynamics in colorectal adenomas indicates CDX2 gain as a predictor of recurrence
D. Fiedler, K. Heselmeyer-Haddad, D. Hirsch, Leanora S. Hernandez +8 more
2018International Journal of Cancer19 citations Open access
Semantic Scholar
High levels of chromosomal copy number alterations and TP53 mutations correlate with poor outcome in younger breast cancer patients.
Ayla Koçak, K. Heselmeyer-Haddad, A. Lischka, D. Hirsch +12 more
2020American Journal of Pathology16 citations Open access
Semantic Scholar
Targeting colorectal cancer (stem-like) cells using LGR5 directed antibody drug conjugates.
D. Hirsch, T. Ried
2016Annals of Translational Medicine16 citations Open access
Semantic Scholar
Genome-wide DNA methylation analysis of colorectal adenomas with and without recurrence reveals an association between cytosine-phosphate-guanine methylation and histological subtypes
D. Fiedler, D. Hirsch, N. El Hajj, H. Yang +9 more
2019Genes, Chromosomes and Cancer15 citations Open access
Semantic Scholar
Single-Cell–Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response
Rüdiger Braun, Lena Anthuber, D. Hirsch, Darawalee Wangsa +18 more
2020Clinical Cancer Research13 citations Open access
Semantic Scholar
Human Stem Cells Promote Liver Regeneration After Partial Hepatectomy in BALB/C Nude Mice.
S. Wabitsch, C. Benzing, F. Krenzien, Katrin Splith +10 more
2019Journal of Surgical Research13 citations Open access
Semantic Scholar
Alpha-1 Antitrypsin-Expressing Mesenchymal Stromal Cells Confer a Long-Term Survival Benefit in a Mouse Model of Lethal GvHD.
S. Geiger, E. I. Ozay, Ulf Geumann, M. Hereth +9 more
2019Molecular Therapy12 citations Open access
Semantic Scholar
Three Novel Mutations in POU1F1 in Israeli Patients with Combined Pituitary Hormone Deficiency
G. Gat-Yablonski, A. Klar, D. Hirsch, Α. Eliakim +3 more
2005Journal of Pediatric Endocrinology & Metabolism (JPEM)12 citations
Semantic Scholar
Involvement of platelet-derived VWF in metastatic growth of melanoma in the brain
J. R. Robador, M. Feinauer, S. W. Schneider, F. T. Mayer +17 more
2021Neuro-Oncology Advances11 citations Open access
Semantic Scholar
Transcriptome profiling of LGR5 positive colorectal cancer cells
D. Hirsch, Yue Hu, T. Ried, R. Moll +1 more
2014Genomics Data11 citations Open access
Semantic Scholar
Single Cell Genetic Profiling of Tumors of Breast Cancer Patients Aged 50 Years and Older Reveals Enormous Intratumor Heterogeneity Independent of Individual Prognosis
A.-S. Liegmann, K. Heselmeyer-Haddad, A. Lischka, D. Hirsch +10 more
2021Cancers10 citations Open access
Semantic Scholar
Clinical responses to PD-1 inhibition and their molecular characterization in six patients with mismatch repair-deficient metastatic cancer of the digestive system
D. Hirsch, T. Gaiser, K. Merx, Simone Weingaertner +6 more
2020Journal of Cancer Research and Clinical Oncology10 citations Open access
Semantic Scholar
Pringle maneuver increases the risk of anastomotic leakage after colonic resection in rats.
B. Jansen-Winkeln, E. Tagkalos, A. Heimann, T. Gaiser +5 more
2018HPB10 citations Open access
Semantic Scholar
Clinical and Histopathologic Features of Colorectal Adenocarcinoma in Crohn’s Disease
C. Galata, D. Hirsch, W. Reindl, S. Post +4 more
2017Journal of Clinical Gastroenterology10 citations Open access
Semantic Scholar
MYC gene amplification is a rare event in atypical fibroxanthoma and pleomorphic dermal sarcoma
T. Gaiser, D. Hirsch, A. Orouji, Marisa Bach +6 more
2018OncoTarget9 citations Open access
Semantic Scholar
Nijmegen breakage syndrome: the clearance pathway for mutant nibrin protein is allele specific.
Bastian Salewsky, Petra Wessendorf, D. Hirsch, Harald Krenzlin +1 more
2013Gene9 citations
Semantic Scholar
Comprehensive biomarker analysis of long-term response to trastuzumab in patients with HER2-positive advanced gastric or gastroesophageal adenocarcinoma.
Isabel Porth, D. Hirsch, Yonca Ceribas, Philip Weidner +9 more
2023European Journal of Cancer8 citations Open access
Semantic Scholar
Newly established gastrointestinal cancer cell lines retain the genomic and immunophenotypic landscape of their parental cancers
D. Hirsch, S. Seyfried, Tobias Staib, D. Fiedler +5 more
2020Scientific Reports8 citations Open access
Semantic Scholar
Morbus-Crohn-assoziierte kolorektale Karzinogenese
D. Hirsch, T. Gaiser
2018Der Pathologe8 citations
Semantic Scholar
Cancer-type specific aneuploidies hard-wire chromosome-wide gene expression patterns of their tissue of origin
Noam Auslander, K. Heselmeyer-Haddad, Sushant Patkar, D. Hirsch +21 more
2019bioRxiv7 citations Open access
Semantic Scholar
DNA-Methylation Analysis as a Tool for Thymoma Classification
T. Gaiser, D. Hirsch, Isabel Porth, F. Sahm +3 more
2022Cancers5 citations Open access
Semantic Scholar
First report on establishment and characterization of a carcinosarcoma tumour cell line model of the bladder
J. Eberhard, D. Hirsch, O. Schilling, W. Dirks +6 more
2021Scientific Reports5 citations Open access
Semantic Scholar
Cecal Resection with Bipolar Sealing Devices in a Rat Model
E. Tagkalos, A. Heimann, T. Gaiser, D. Hirsch +3 more
2020Journal of investigative surgery5 citations
Semantic Scholar
Endoscopic papillectomy or pancreaticoduodenectomy for ampullary lesions: a single center retrospective cohort study
S. Seyfried, G. Kähler, S. Belle, D. Hirsch +3 more
2022Scandinavian Journal of Gastroenterology4 citations
Semantic Scholar
Loss of epithelial cell adhesion molecule (EpCAM) in infiltrative basal cell carcinoma.
M. Gaiser, D. Hirsch, T. Gaiser
2018International Journal of Clinical and Experimental Pathology4 citations
Semantic Scholar
TP53 loss initiates chromosomal instability in high-grade serous ovarian cancer
Daniel Bronder, Darawalee Wangsa, D. Zong, T. Meyer +13 more
2021bioRxiv3 citations Open access
Semantic Scholar
Molecular and Pathological Profiling of Corresponding Treatment-Naïve and Neoadjuvant Pazopanib-Treated High-Risk Soft Tissue Sarcoma Samples of the GISG-04/NOPASS Study
T. Gaiser, C. Sauer, A. Marx, J. Jakob +4 more
2021Biology2 citations Open access
Semantic Scholar
Kolorektale Tumorevolution bei chronisch-entzündlichen Darmerkrankungen
D. Hirsch
2019Der Pathologe2 citations
Semantic Scholar
Abstract 1438: The dynamics of genetic aberrations in Crohn's disease associated colorectal carcinogenesis
D. Hirsch, Darawalee Wangsa, Yue Hu, Jack Zhu +7 more
20172 citations
Semantic Scholar
Author response: Topography of cancer-associated immune cells in human solid tumors
Jakob Nikolas Kather, M. Suarez-Carmona, P. Charoentong, Cleo-Aron Weis +16 more
20181 citations Open access
Semantic Scholar
Gute Remission unter HER2-Blockade bei einem fortgeschrittenen Karzinom des ösophagogastralen Überganges bei nur fokaler HER2-Überexpression
T. Gaiser, D. Hirsch, R. Hofheinz
2017Zeitschrift für Gastroenterologie - German Journal of Gastroenterology1 citations
Semantic Scholar
Abstract 314: Intratumor genetic heterogeneity dictates metastatic subclones in stage II colon cancer
Sanam Yaghoubi, K. Heselmeyer-Haddad, I. Archilla, C. Parra +10 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 4018: Long-term response to Trastuzumab in patients with advanced gastric or gastroesophageal adenocarcinoma - A retrospective study
Isabel Porth, Philip Weidner, S. Lorenzen, W. Weichert +9 more
2022Cancer Research0 citations
Semantic Scholar
Abstract PO-106: Genomic heterogeneity and clonal dynamics of resistance evolution and metastatic progression in rectal cancer
D. Hirsch, Judith Lieberich, K. Heselmeyer-Haddad, Yonca Ceribas +5 more
20200 citations
Semantic Scholar

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