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R. McLaughlin · SciRah

Researcher profile · Semantic Scholar

R. McLaughlin

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R. McLaughlin — researcher profile on SciRah

h-index: 29
Works: 50
Citations: 4,887

Most-cited papers

Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen
D. Ajdic, W. McShan, R. McLaughlin, G. Savic +15 more
2002Proceedings of the National Academy of Sciences of the United States of America1,094 citations Open access
Semantic Scholar
Complete genome sequence of an M1 strain of Streptococcus pyogenes
J. Ferretti, W. McShan, D. Ajdic, D. J. Savić +19 more
2001Proceedings of the National Academy of Sciences of the United States of America998 citations Open access
Semantic Scholar
ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii
T. Durand-Réville, S. Guler, Janelle Comita-Prevoir, Brendan Chen +22 more
2017Nature Microbiology264 citations
Semantic Scholar
The Resistome of Pseudomonas aeruginosa in Relationship to Phenotypic Susceptibility
V. Kos, Maxime Déraspe, R. McLaughlin, James D. Whiteaker +4 more
2014Antimicrobial Agents and Chemotherapy258 citations Open access
Semantic Scholar
Molecular Mechanisms of Sulbactam Antibacterial Activity and Resistance Determinants in Acinetobacter baumannii
William F. Penwell, A. Shapiro, R. Giacobbe, R. Gu +7 more
2015Antimicrobial Agents and Chemotherapy220 citations Open access
Semantic Scholar
Multiyear, Multinational Survey of the Incidence and Global Distribution of Metallo-β-Lactamase-Producing Enterobacteriaceae and Pseudomonas aeruginosa
K. Kazmierczak, S. Rabine, M. Hackel, R. McLaughlin +4 more
2015Antimicrobial Agents and Chemotherapy189 citations Open access
Semantic Scholar
Lipooligosaccharides (LOS) of some Haemophilus species mimic human glycosphingolipids, and some LOS are sialylated
R. Mandrell, R. McLaughlin, Y. A. Kwaik, A. Lesse +4 more
1992Infection and Immunity186 citations Open access
Semantic Scholar
Azaindoles: noncovalent DprE1 inhibitors from scaffold morphing efforts, kill Mycobacterium tuberculosis and are efficacious in vivo.
Pravin S. Shirude, R. Shandil, C. Sadler, M. Naik +35 more
2013Journal of Medicinal Chemistry154 citations
Semantic Scholar
Selection and molecular characterization of ceftazidime/avibactam-resistant mutants in Pseudomonas aeruginosa strains containing derepressed AmpC.
S. Lahiri, G. Walkup, James D. Whiteaker, T. Palmer +9 more
2015Journal of Antimicrobial Chemotherapy120 citations Open access
Semantic Scholar
Analysis of Staphylococcus aureus clinical isolates with reduced susceptibility to ceftaroline: an epidemiological and structural perspective.
R. Alm, R. McLaughlin, V. Kos, H. Sader +2 more
2014Journal of Antimicrobial Chemotherapy106 citations
Semantic Scholar
Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis.
S. Tantry, Shankar D. Markad, V. Shinde, J. Bhat +50 more
2017Journal of Medicinal Chemistry105 citations
Semantic Scholar
Pharmacokinetics/pharmacodynamics of a β-lactam and β-lactamase inhibitor combination: a novel approach for aztreonam/avibactam.
Renu Singh, Aryun Kim, M. Angela Tanudra, Jennifer J. Harris +5 more
2015Journal of Antimicrobial Chemotherapy92 citations Open access
Semantic Scholar
Characterization of the Novel DNA Gyrase Inhibitor AZD0914: Low Resistance Potential and Lack of Cross-Resistance in Neisseria gonorrhoeae
R. Alm, S. Lahiri, A. Kutschke, Linda G. Otterson +7 more
2014Antimicrobial Agents and Chemotherapy84 citations Open access
Semantic Scholar
Lead optimization of 1,4-azaindoles as antimycobacterial agents.
Pravin S. Shirude, R. Shandil, M. Manjunatha, C. Sadler +22 more
2014Journal of Medicinal Chemistry80 citations Open access
Semantic Scholar
Small-Molecule Inhibitors of Gram-Negative Lipoprotein Trafficking Discovered by Phenotypic Screening
Sarah M. McLeod, P. Fleming, K. MacCormack, R. McLaughlin +5 more
2015Journal of Bacteriology69 citations Open access
Semantic Scholar
Streptococcal Histone-Like Protein: Primary Structure ofhlpA and Protein Binding to Lipoteichoic Acid and Epithelial Cells
M. Stinson, R. McLaughlin, Suk-Ho Choi, Zaira E. Juarez +1 more
1998Infection and Immunity67 citations Open access
Semantic Scholar
Markerless Escherichia coli rrn Deletion Strains for Genetic Determination of Ribosomal Binding Sites
Selwyn Quan, O. Skovgaard, R. McLaughlin, E. Buurman +1 more
2015G3: Genes, Genomes, Genetics63 citations Open access
Semantic Scholar
Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated Efficacy
Aryun Kim, A. Kutschke, D. Ehmann, Sara A Patey +13 more
2015Antimicrobial Agents and Chemotherapy62 citations Open access
Semantic Scholar
Triaminopyrimidine is a fast-killing and long-acting antimalarial clinical candidate
S. Hameed P., S. Solapure, Vikas R Patil, Philipp P. Henrich +45 more
2015Nature Communications62 citations Open access
Semantic Scholar
Frequency and Mechanism of Spontaneous Resistance to Sulbactam Combined with the Novel β-Lactamase Inhibitor ETX2514 in Clinical Isolates of Acinetobacter baumannii
Sarah M. McLeod, A. Shapiro, Samir H. Moussa, M. Johnstone +3 more
2017Antimicrobial Agents and Chemotherapy56 citations Open access
Semantic Scholar
Characterization of a Respiratory Syncytial Virus L Protein Inhibitor
Choi-Lai Tiong-Yip, Lisa Aschenbrenner, Kenneth D. Johnson, R. McLaughlin +4 more
2014Antimicrobial Agents and Chemotherapy52 citations Open access
Semantic Scholar
Molecular determinants of AcrB-mediated bacterial efflux implications for drug discovery.
J. Manchester, E. Buurman, G. Bisacchi, R. McLaughlin
2012Journal of Medicinal Chemistry51 citations
Semantic Scholar
Diarylthiazole: an antimycobacterial scaffold potentially targeting PrrB-PrrA two-component system.
Eknath Bellale, M. Naik, Varun Vb, Anisha Ambady +16 more
2014Journal of Medicinal Chemistry46 citations Open access
Semantic Scholar
Molecular characterization of MRSA isolates bracketing the current EUCAST ceftaroline-susceptible breakpoint for Staphylococcus aureus: the role of PBP2a in the activity of ceftaroline.
S. Lahiri, R. McLaughlin, James D. Whiteaker, J. Ambler +1 more
2015Journal of Antimicrobial Chemotherapy44 citations
Semantic Scholar
Characterization of two transposon mutants from Haemophilus influenzae type b with altered lipooligosaccharide biosynthesis.
N. J. Phillips, R. McLaughlin, Theresa J. Miller, Michael A. Apicella +1 more
1996Biochemistry38 citations
Semantic Scholar
Elucidation of Mechanisms of Ceftazidime Resistance among Clinical Isolates of Pseudomonas aeruginosa by Using Genomic Data
V. Kos, R. McLaughlin, H. Gardner
2016Antimicrobial Agents and Chemotherapy34 citations Open access
Semantic Scholar
Use of protozoans for microbial control of insects
R. McLaughlin
197132 citations
Semantic Scholar
Homologous Recombination within Large Chromosomal Regions Facilitates Acquisition of β-Lactam and Vancomycin Resistance in Enterococcus faecium
Mónica A. García-Solache, F. Lebreton, R. McLaughlin, James D. Whiteaker +2 more
2016Antimicrobial Agents and Chemotherapy31 citations Open access
Semantic Scholar
Characterization of Chimeric Lipopolysaccharides from Escherichia coli Strain JM109 Transformed with Lipooligosaccharide Synthesis Genes (lsg) from Haemophilus influenzae *
N. Phillips, Theresa J. Miller, Jeffrey J. Engstrom, W. Melaugh +3 more
2000Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Effect of inactivation of gtf genes on adherence of Streptococcus downei.
S. M. Colby, R. McLaughlin, Joseph J. Ferretti, R. R. B. Russell
1999Oral Microbiology and Immunology29 citations Open access
Semantic Scholar
Development of a Novel Loop-Mediated Isothermal Amplification Method to Detect Guiana Extended-Spectrum (GES) β-Lactamase Genes in Pseudomonas aeruginosa
Chika Takano, Mitsuko Seki, D. W. Kim, H. Gardner +4 more
2019Frontiers in Microbiology26 citations Open access
Semantic Scholar
Identification of a major protein upon phosphate starvation of Pseudomonas aeruginosa PAO1
K. T. Madhusudhan, R. McLaughlin, N. Komori, H. Matsumoto
2003Journal of Basic Microbiology24 citations
Semantic Scholar
Characterization of novel respiratory syncytial virus inhibitors identified by high throughput screen.
V. Laganas, Ewan F. Dunn, R. McLaughlin, Lai-Tiong-Yip Choi +4 more
2015Antiviral Research23 citations
Semantic Scholar
Identification of unique in-frame deletions in OprD among clinical isolates of Pseudomonas aeruginosa.
V. Kos, R. McLaughlin, H. Gardner
2016Pathogens and Disease17 citations
Semantic Scholar
A Novel High-Throughput Cell-Based Assay Aimed at Identifying Inhibitors of DNA Metabolism in Bacteria
Jun Fan, B. D. de Jonge, K. MacCormack, Shubha Sriram +7 more
2014Antimicrobial Agents and Chemotherapy17 citations Open access
Semantic Scholar
Generation of lipooligosaccharide mutants of Haemophilus influenzae type b
R. McLaughlin, S. Spinola, M. Apicella
1992Journal of Bacteriology16 citations Open access
Semantic Scholar
Development of a novel loop-mediated isothermal amplification assay for ß-lactamase gene identification using clinical isolates of Gram-negative bacteria
E. J. Kim, Jiwon Lee, Youngbae Yoon, Donghyun Lee +14 more
2023Frontiers in Cellular and Infection Microbiology11 citations Open access
Semantic Scholar
Illicit Transport via Dipeptide Transporter Dpp is Irrelevant to the Efficacy of Negamycin in Mouse Thigh Models of Escherichia coli Infection.
D. McKinney, Natascha Bezdenejnih-Snyder, K. Farrington, Jian Guo +6 more
2015ACS Infectious Diseases10 citations
Semantic Scholar
Neisseria gonorrhoeae infection in women increases with rising numbers of gonococci in partners: Chlamydia coinfection in women increases gonococcal burden.
Xiao-Hong Su, Wen-Jing Le, Xiao-Feng Zhu, Sai Li +13 more
2022Journal of Infectious Diseases8 citations Open access
Semantic Scholar
Cloning and analysis of lipooligosaccharide synthesis genes of Haemophilus influenzae type b that assemble or expose a 2-keto-3-deoxyoctulosonic acid epitope in Escherichia coli.
Y. A. Kwaik, R. McLaughlin, M. Apicella, S. Spinola
1992Journal of Infectious Diseases6 citations
Semantic Scholar
Transposon mutagenesis and complementation of the fructokinase gene in Rhizobium leguminosarum biovar trifolii.
R. McLaughlin, T. A. Hughes
1989Journal of General Microbiology6 citations Open access
Semantic Scholar
Plant Microfossils from the Bruhn Lignite
R. McLaughlin
19574 citations
Semantic Scholar
Sulbactam combined with the Novel β-lactamase Inhibitor ETX2514 for the Treatment of Multidrug-resistant Acinetobacter baumannii Infections
Sarah M. McLeod, A. Shapiro, Samir H. Moussa, Nicole M. Carter +6 more
20163 citations Open access
Semantic Scholar
β-lactamase Characterization of Baseline Pseudomonas aeruginosa (PSA) from Five Ceftazidime-avibactam (CAZ-AVI) Phase 3 Clinical Trials
R. Mendes, M. Castanheira, Leah N. Woosley, G. Stone +3 more
20172 citations Open access
Semantic Scholar
Credible leads to Incredible TM Application Note Useful for Pharmaceutical , Specialty Chemical , and Other Green Chemistry Applications
G. Monga, J. Sohn, Quan Zhang, R. McLaughlin +1 more
20190 citations
Semantic Scholar
Pseudomonas aeruginosa PcrV and Psl Antigens are Conserved in Diverse Hospital Isolates Collected from an International Surveillance Study
D. Tabor, Yu Li, A. Nyborg, R. McLaughlin +7 more
20160 citations Open access
Semantic Scholar
Triaminopyrimidines antimalarial agent NatComm 2015
P. Hameed, S. Solapure, Vikas R Patil, Philipp P. Henrich +45 more
20150 citations
Semantic Scholar
Lipoteichoic Acid and Epithelial Cells and Protein Binding to hlpA Structure of Streptococcal Histone-Like Protein: Primary
John P. Barnard, M. Stinson, R. McLaughlin, Suk-Ho Choi +1 more
20140 citations
Semantic Scholar
Resistance the Binding Pocket , and Implications for Mechanism of Inhibition , Conservation of-Lactamases : β Avibactam and Class C
N. Olivier, R. Alm, S. Lahiri, M. Johnstone +2 more
20140 citations
Semantic Scholar
S19.3 Structural and immunochemical characterization ofHaemophilus influenzae lipooligosaccharides
N. J. Phillips, William Melaugh, R. McLaughlin, M. Apicella +1 more
1993Glycoconjugate Journal0 citations
Semantic Scholar

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