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P. Dalezis · SciRah

Researcher profile · Semantic Scholar

P. Dalezis

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P. Dalezis — researcher profile on SciRah

h-index: 10
Works: 27
Citations: 331

Most-cited papers

In vitro and in vivo antitumor activity of platinum(II) complexes with thiosemicarbazones derived from 2-formyl and 2-acetyl pyridine and containing ring incorporated at N(4)-position: synthesis, spectroscopic study and crystal structure of platinum(II) complexes with thiosemicarbazones, potential a
D. Kovala‐Demertzi, A. Papageorgiou, Leuteris Papathanasis, Alexandros Alexandratos +3 more
2009European journal of medicinal chemistry67 citations
Semantic Scholar
Synthesis, characterization, crystal structures, in vitro and in vivo antitumor activity of palladium(II) and zinc(II) complexes with 2-formyl and 2-acetyl pyridine N(4)-1-(2-pyridyl)-piperazinyl thiosemicarbazone
D. Kovala‐Demertzi, Alexandros Alexandratos, A. Papageorgiou, P. Yadav +2 more
200862 citations
Semantic Scholar
Synthesis and biological evaluation of a Platinum(II)-c(RGDyK) conjugate for integrin-targeted photodynamic therapy.
Theodora Chatzisideri, S. Thysiadis, S. Katsamakas, P. Dalezis +7 more
2017European journal of medicinal chemistry43 citations
Semantic Scholar
Synthesis and evaluation of new steroidal lactam conjugates with aniline mustards as potential antileukemic therapeutics.
D. Trafalis, E. Geromichalou, P. Dalezis, Nikolaos Nikoleousakos +1 more
2016Steroids22 citations
Semantic Scholar
In silico study of potential antiviral activity of copper(II) complexes with non–steroidal anti–inflammatory drugs on various SARS–CoV–2 target proteins
E. Geromichalou, D. Trafalis, P. Dalezis, G. Malis +2 more
2022Journal of Inorganic Biochemistry15 citations Open access
Semantic Scholar
N-heterocyclic-carbene vs diphosphine auxiliary ligands in thioamidato Cu(I) and Ag(I) complexes towards the development of potent and dual-activity antibacterial and apoptosis-inducing anticancer agents.
D. Varna, G. Geromichalos, Dimitra K Gioftsidou, D. Tzimopoulos +5 more
2023Journal of Inorganic Biochemistry13 citations
Semantic Scholar
Silver complexes with heterocyclic thioamide and tertiary arylphosphane ligands: Synthesis, crystal structures, in vitro and in silico antibacterial and cytotoxic activity, and interaction with DNA.
Despoina Anastasiadou, E. Geromichalou, Eleni Tsavea, George Psomas +6 more
2020Journal of Inorganic Biochemistry13 citations
Semantic Scholar
Novel c(RGDyK)-based conjugates of POPAM and 5-fluorouracil for integrin-targeted cancer therapy.
S. Thysiadis, S. Katsamakas, P. Dalezis, Theodora Chatzisideri +2 more
2017Future Medicinal Chemistry13 citations
Semantic Scholar
Silver(I) complexes bearing heterocyclic thioamide ligands with NH2 and CF3 substituents: effect of ligand group substitution on antibacterial and anticancer properties.
D. Varna, E. Geromichalou, A. Hatzidimitriou, R. Papi +6 more
2022Dalton Transactions12 citations Open access
Semantic Scholar
Synthesis and biological activity of bisindole derivatives as novel MARK4 inhibitors
Maria Voura, Saleha Anwar, S. Thysiadis, Parvez Khan +4 more
2022European Journal of Medicinal Chemistry Reports11 citations Open access
Semantic Scholar
Discovery of steroidal lactam conjugates of POPAM-NH2 with potent anticancer activity.
D. Trafalis, P. Dalezis, E. Geromichalou, Sofia Sagredou +5 more
2019Future Medicinal Chemistry9 citations
Semantic Scholar
Amine-substituted heterocyclic thioamide Cu(I) and Ag(I) complexes as effective anticancer and antibacterial agents targeting the periplasm of E. coli bacteria.
D. Varna, G. Geromichalos, P. Dalezis, A. Hatzidimitriou +7 more
2024European journal of medicinal chemistry7 citations
Semantic Scholar
In silico/in vitro study of hybrid D-modified steroidal alkylator anticancer activity using uridine phosphorylase as target protein.
G. Geromichalos, E. Geromichalou, C. Camoutsis, M. Kontos +5 more
2011Anticancer Research7 citations
Semantic Scholar
Inhibition of Cancer Cell Proliferation and Bacterial Growth by Silver(I) Complexes Bearing a CH3-Substituted Thiadiazole-Based Thioamide
D. Varna, E. Geromichalou, Georgia Karlioti, R. Papi +6 more
2023Molecules6 citations Open access
Semantic Scholar
Synthesis and Biological Evaluation of a c(RGDyK) Peptide Conjugate of SRPIN803
G. Leonidis, P. Dalezis, D. Trafalis, D. Beis +5 more
2021ACS Omega6 citations Open access
Semantic Scholar
Azasteroid Alkylators as Dual Inhibitors of AKT and ERK Signaling for the Treatment of Ovarian Carcinoma
P. Dalezis, E. Geromichalou, A. Polonifi, Sofia Sagredou +5 more
2020Cancers6 citations Open access
Semantic Scholar
Cytocidal Antitumor Effects against Human Ovarian Cancer Cells Induced by B-Lactam Steroid Alkylators with Targeted Activity against Poly (ADP-Ribose) Polymerase (PARP) Enzymes in a Cell-Free Assay
Nikolaos Nikoleousakos, P. Dalezis, A. Polonifi, E. Geromichalou +5 more
2021Biomedicines5 citations Open access
Semantic Scholar
3,6-Disubstituted 1,2,4-Triazolo[3,4-b]Thiadiazoles with Anticancer Activity Targeting Topoisomerase II Alpha
Sofia Sagredou, P. Dalezis, Nikolaos Nikoleousakos, M. Nikolaou +5 more
2020OncoTargets and Therapy5 citations Open access
Semantic Scholar
Synthesis and biological studies of c(RGDyK) conjugates of cucurbitacins.
Theodora Chatzisideri, P. Dalezis, G. Leonidis, Spyridon Bousis +3 more
2021Future Medicinal Chemistry4 citations
Semantic Scholar
Effects of a Novel Thiadiazole Derivative with High Anticancer Activity on Cancer Cell Immunogenic Markers: Mismatch Repair System, PD-L1 Expression, and Tumor Mutation Burden
Sofia Sagredou, P. Dalezis, E. Papadopoulou, Maria Voura +6 more
2021Pharmaceutics3 citations Open access
Semantic Scholar
Predictive value of 8-hydroxy-2′-deoxyguanosine and 8-nitroguanine production in radiation-induced skin damage after postoperative breast cancer radiotherapy
Emmanouil K. Verigos, Sofia Sagredou, Kosmas E. Verigos, K. Orfanakos +6 more
2025Exploration of Targeted Anti-tumor Therapy1 citations Open access
Semantic Scholar
Antitumour and cytogenetic effects of modified steroidal derivatives of propenoic acid: in vivo/in vitro studies.
A. Papageorgiou, C. Mourelatos, G. Geromichalos, E. Geromichalou +2 more
2010Anticancer Research1 citations
Semantic Scholar
Novel Active Homo-Aza (Lactam) Steroidal Antimetabolites for the Treatment of Human Pancreatic and Colorectal Cancer
K. Alifieris, P. Dalezis, Sofia Sagredou, I. Anastasiou +9 more
2026Pharmaceuticals0 citations Open access
Semantic Scholar
Synthesis and Cytotoxic Effects of 3,6‐Bis‐indolyl 2,5‐Dihydroxybenzoquinone Acetates
Maria Tsanakopoulou, P. Dalezis, C. Karakousi, Dionysia Schina +3 more
2022ChemistrySelect0 citations
Semantic Scholar
3,6-Disubstituted 1,2,4-Triazolo[3,4- b ] Thiadiazoles with Anticancer Activity Targeting Topoisomerase II Alpha
P. Dalezis, Nikolaos Nikoleousakos, M. Nikolaou, Maria Voura +4 more
20200 citations
Semantic Scholar
461 Further studies on the antitumour activity of a hybrid synthetic antitumour ester in combination with adriamycin on murine melanoma B-16
A. Papageorgiou, E. Stergiou, E. Geromichalou, G. Geromichalos +3 more
20100 citations
Semantic Scholar
1218 In vivo antitumor activity of platinum(II) complexes with thiosemicarbazones derived from 2-formyl and 2-acetyl pyridine and containing ring incorporated at N(4)-position
A. Papageorgiou, E. Stergiou, P. Dalezis, E. Chrysogelou +3 more
20090 citations
Semantic Scholar

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