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Pawan Noel · SciRah

Researcher profile · Semantic Scholar

Pawan Noel

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Pawan Noel — researcher profile on SciRah

h-index: 18
Works: 53
Citations: 1,695

Most-cited papers

Triptolide and Its Derivatives as Cancer Therapies.
Pawan Noel, D. V. Von Hoff, A. Saluja, Mohana R. Velagapudi +2 more
2019TIPS - Trends in Pharmacological Sciences285 citations
Semantic Scholar
Single-cell transcriptome analysis of tumor and stromal compartments of pancreatic ductal adenocarcinoma primary tumors and metastatic lesions
Wei Lin, Pawan Noel, E. Borazanci, Jeeyun Lee +12 more
2020Genome Medicine270 citations Open access
Semantic Scholar
Peripancreatic fat necrosis worsens acute pancreatitis independent of pancreatic necrosis via unsaturated fatty acids increased in human pancreatic necrosis collections
Pawan Noel, Krutika Patel, Chandra Durgampudi, R. N. Trivedi +18 more
2014Gut158 citations Open access
Semantic Scholar
A multiscale map of the stem cell state in pancreatic adenocarcinoma
Nikki K. Lytle, L. P. Ferguson, Nirakar Rajbhandari, K. Gilroy +29 more
2019Cell138 citations Open access
Semantic Scholar
Pancreatic triglyceride lipase mediates lipotoxic systemic inflammation.
Cristiane de Oliveira, B. Khatua, Pawan Noel, Sergiy Kostenko +17 more
2020Journal of Clinical Investigation131 citations Open access
Semantic Scholar
Lipolysis of visceral adipocyte triglyceride by pancreatic lipases converts mild acute pancreatitis to severe pancreatitis independent of necrosis and inflammation.
Krutika Patel, R. N. Trivedi, Chandra Durgampudi, Pawan Noel +4 more
2015American Journal of Pathology128 citations Open access
Semantic Scholar
Fibrosis Reduces Severity of Acute-on-Chronic Pancreatitis in Humans
C. Acharya, Rachel A. Cline, Deepthi Jaligama, Pawan Noel +12 more
2013Gastroenterology105 citations Open access
Semantic Scholar
SuperCT: a supervised-learning framework for enhanced characterization of single-cell transcriptomic profiles
Peng Xie, Ming-Xuan Gao, Chunming Wang, Jian-Fei Zhang +6 more
2019Nucleic Acids Research74 citations Open access
Semantic Scholar
Adipose saturation reduces lipotoxic systemic inflammation and explains the obesity paradox
B. Khatua, Bara El-Kurdi, Krutika Patel, Christopher Rood +8 more
2021Science Advances59 citations Open access
Semantic Scholar
Triptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts
Pawan Noel, Shaimaa Hussein, Serina Ng, Corina E. Antal +9 more
2020Oncogenesis57 citations Open access
Semantic Scholar
The Association of yKu With Subtelomeric Core X Sequences Prevents Recombination Involving Telomeric Sequences
Marcus E. Marvin, M. Becker, Pawan Noel, S. Hardy +2 more
2009Genetics37 citations Open access
Semantic Scholar
GASTROINTESTINAL , HEPATOBILIARY , AND PANCREATIC PATHOLOGY Acute Lipotoxicity Regulates Severity of Biliary Acute Pancreatitis without Affecting Its Initiation
Chandra Durgampudi, Pawan Noel, Krutika Patel, Rachel A. Cline +10 more
36 citations
Semantic Scholar
Preparation and Metabolic Assay of 3-dimensional Spheroid Co-cultures of Pancreatic Cancer Cells and Fibroblasts
Pawan Noel, R. Muñoz, George W. T. Rogers, Andy Neilson +2 more
2017Journal of Visualized Experiments27 citations Open access
Semantic Scholar
Acute lipotoxicity regulates severity of biliary acute pancreatitis without affecting its initiation.
Chandra Durgampudi, Pawan Noel, Krutika Patel, Rachel A. Cline +10 more
2014American Journal of Pathology25 citations Open access
Semantic Scholar
Single-Cell Sequencing in Precision Medicine.
J. Wiedmeier, Pawan Noel, Wei Lin, D. V. Von Hoff +1 more
2019Cancer treatment and research22 citations
Semantic Scholar
The Effects of Synthetically Modified Natural Compounds on ABC Transporters
Daniel D. E. Dantzic, Pawan Noel, F. Merien, Dong-Xu Liu +4 more
2018Pharmaceutics21 citations Open access
Semantic Scholar
Different Aneuploidies Arise From the Same Bridge-Induced Chromosomal Translocation Event in Saccharomyces cerevisiae
Beatrice Rossi, Pawan Noel, C. Bruschi
2010Genetics20 citations Open access
Semantic Scholar
Fatty Acid Ethyl Esters Are Less Toxic Than Their Parent Fatty Acids Generated during Acute Pancreatitis.
Krutika Patel, Chandra Durgampudi, Pawan Noel, R. N. Trivedi +2 more
2016American Journal of Pathology19 citations Open access
Semantic Scholar
Amphipathic Liponecrosis Impairs Bacterial Clearance and Causes Infection During Sterile Inflammation
Sergiy Kostenko, B. Khatua, Shubham Trivedi, Anoop Narayana Pillai +15 more
2023Gastroenterology16 citations Open access
Semantic Scholar
Carboxyl Ester Lipase May Not Mediate Lipotoxic Injury during Severe Acute Pancreatitis.
B. Khatua, R. N. Trivedi, Pawan Noel, Krutika Patel +6 more
2019American Journal of Pathology16 citations Open access
Semantic Scholar
ADP-ribosylation Factor 1 Protein Regulates Trypsinogen Activation via Organellar Trafficking of Procathepsin B Protein and Autophagic Maturation in Acute Pancreatitis*
L. Orlichenko, D. Stolz, Pawan Noel, J. Behari +2 more
2012Journal of Biological Chemistry13 citations Open access
Semantic Scholar
Characterization and Predictive Value of Near Infrared 2-Deoxyglucose Optical Imaging in Severe Acute Pancreatitis
Cristiane de Oliveira, Krutika Patel, V. Mishra, R. N. Trivedi +4 more
2016PLoS ONE10 citations Open access
Semantic Scholar
Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium
V. Mishra, Rachel A. Cline, Pawan Noel, J. Karlsson +10 more
2013PLoS ONE9 citations Open access
Semantic Scholar
Potential Influence of Intravenous Lipids on the Outcomes of Acute Pancreatitis
Krutika Patel, Pawan Noel, Vijay P. Singh
2014Nutrition in clinical practice8 citations Open access
Semantic Scholar
Hypothermia slows sequential and parallel steps initiated during caerulein pancreatitis.
V. Mishra, Krutika Patel, R. N. Trivedi, Pawan Noel +5 more
2014Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]5 citations
Semantic Scholar
CGE23-072: The Frequency of Androgen Receptor Splice Variant 7 (AR-V7) in Solid Tumors
Z. Gatalica, J. Hoag, D. Hall, F. Alyaqoub +7 more
2023The Journal of the National Comprehensive Cancer Network2 citations
Semantic Scholar
The Wnt signaling pathway in gastrointestinal cancers.
Z. Gatalica, Turgut Dogruluk, Pawan Noel, Susan M. Dombrowski +7 more
2023Journal of Clinical Oncology2 citations Open access
Semantic Scholar
SuperCT: A supervised-learning-framework to enhance the characterization of single-cell transcriptomic profiles
Peng Xie, Ming-Xuan Gao, Chunming Wang, Pawan Noel +5 more
2018bioRxiv1 citations Open access
Semantic Scholar
Abstract LB-B27: Novel antitumor agent GZ17-6.02 exerts discrete effects on transcriptional regulation in pancreatic cancer cells and cancer associated fibroblasts
Emily Rodela, Pawan Noel, Shaimaa Hussein, Yin C. Lin +2 more
20181 citations
Semantic Scholar
Abstract 2978: Discrete super-enhancer networks in pancreatic cancer cells and cancer associated fibroblasts are targeted and modulated by triptolide
Pawan Noel, Serina Ng, R. Muñoz, D. V. Von Hoff +1 more
20171 citations
Semantic Scholar
Abstract P5-14-12: ESR1-alterations in HR+HER2- breast cancer patients
G. Basu, S. Udhane, Susan M. Dombrowski, L. Hong +15 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 1263: Comprehensive genomic profiling to identify biomarkers predictive of response to immunotherapy
Pawan Noel, D. Hall, S. Udhane, Min Wang +6 more
2022Cancer Research0 citations
Semantic Scholar
Comprehensive genomic profiling to identify gene alterations in DNA repair pathway across solid tumors.
K. McDonnell, G. Basu, J. Hoag, D. Hall +14 more
2022Journal of Clinical Oncology0 citations
Semantic Scholar
Comprehensive whole-exome and transcriptome profiling to identify actionable alterations associated with response to PARP inhibitors in breast cancer.
Susan M. Dombrowski, S. Udhane, G. Basu, D. Hall +10 more
2022Journal of Clinical Oncology0 citations
Semantic Scholar
Abstract 3121: Characterization of nab-paclitaxel resistant and gemcitabine resistant BxPC3 and MIA PaCa-2 pancreatic cancer cells
Danielle M. Arias, Jan P. Collins, Pawan Noel, D. V. Von Hoff +1 more
2021Tumor Biology0 citations
Semantic Scholar
Genomic profiling of gastrointestinal cancers by comprehensive tumor-normal sequencing.
F. Alyaqoub, Pawan Noel, S. Szelinger, Thanemozhi Natarajan +6 more
20210 citations
Semantic Scholar
Tu1455 – Carboxyl Ester Lipase Does Not Mediate Lipotoxic Injury Under Conditions Relevant to Severe Acute Pancreatitis
B. Khatua, R. N. Trivedi, Pawan Noel, C. Oliveira +3 more
2019Gastroenterology0 citations Open access
Semantic Scholar
Abstract A37: Mapping super-enhancer signatures in pancreatic ductal adenocarcinoma, cancer-associated fibroblasts and their targeting by epigenetic inhibitors
Pawan Noel, Shaimaa Hussein, Kenian Chen, D. V. Von Hoff +2 more
20190 citations
Semantic Scholar
Abstract 282: Minnelide improves the efficacy of the nab-paclitaxel plus gemcitabine plus cisplatin chemotherapy in mouse models of PDAC
Liang Ng, Pawan Noel, Stephanie Mou, D. V. Von Hoff +1 more
2019Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Abstract 5353: Single cell RNA sequencing of pancreatic ductal adenocarcinoma reveals tumor heterogeneity
Pawan Noel, Wei Lin, E. Borazanci, A. Amini +5 more
2018Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Abstract LB-A28: Super-enhancer signatures of pancreatic ductal adenocarcinoma and associated fibroblasts
Shaimaa Hussein, Pawan Noel, Kenian Chen, Lauren Metang +3 more
20180 citations
Semantic Scholar
Lipotoxicity May Result in Inflammatory Cell Death and Associated Immune Paralysis During Severe Acute Pancreatitis (SAP)
B. El Kurdi, Jordan R. Yaron, S. Masood, Pawan Noel +4 more
20170 citations
Semantic Scholar
Fatty Acid Ethyl Esters Are Less Toxic Than Their Parent Fatty Acids Generated during 77 78 79 80 81 Acute Pancreatitis
Krutika Patel, Chandra Durgampudi, Pawan Noel, R. N. Trivedi +2 more
20160 citations
Semantic Scholar
Sa1814 Leukotriene B4 Is Enriched in Human Pancreatic Post Inflammatory Collections and Its Generation May Mediate Unsaturated Fatty Acid Toxicity in Acute Pancreatitis
Pawan Noel, Krutika Patel, R. N. Trivedi, Cristiane de Oliveira +10 more
20150 citations
Semantic Scholar
255 High Unsaturated Fat Diets and Unsaturated Visceral Fat Worsen Acute Pancreatitis (AP) Outcomes At Lower Body Mass Index (BMI)
Krutika Patel, Pawan Noel, R. N. Trivedi, Cristiane de Oliveira +1 more
20150 citations
Semantic Scholar
Sa1791 Biliopancreatic Duct Ligation in Rats Is More Representative of Human Biliary Acute Pancreatitis (AP) Than Bile Acid Infusion
Vijay P. Singh, Krutika Patel, Chandra Durgampudi, Pawan Noel +11 more
20140 citations
Semantic Scholar
Fibrosis reduces lipolytic flux, ameliorating acute on chronic pancreatitis (CP)
C. Acharya, Rachel A. Cline, Deepthi Jaligama, Pawan Noel +6 more
20130 citations
Semantic Scholar
Unsaturated-triglyceride toxicity to pancreatic acinar cells is mediated by lipolysis
Pawan Noel, Rachel A. Cline, Chandra Durgampudi, C. Acharya +2 more
20130 citations
Semantic Scholar
Sa1852 Reduction of Lipotoxicity by Two Distinct Lipase Inhibitors Improves Local, Systemic, Inflammatory Outcomes and Mortality in a Model of Biliary Severe Acute Pancreatitis (SAP) Without Interfering With the Primary Insult
Chandra Durgampudi, Pawan Noel, Krutika Patel, Rachel A. Cline +7 more
20130 citations
Semantic Scholar
Lipolysis of unsaturated triglycerides worsens acute pancreatitis (AP) outcomes in a model mimicking human disease
Chandra Durgampudi, Pawan Noel, Rachel A. Cline, C. Acharya +3 more
20130 citations
Semantic Scholar

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Krutika Patel×21
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Vijay P. Singh×20
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Hai-Yong Han×16
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D. V. Von Hoff×15
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Rachel A. Cline×10

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Cristiane de Oliveira×9

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