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J. Madrenas · SciRah

Researcher profile · Semantic Scholar

J. Madrenas

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J. Madrenas — researcher profile on SciRah

h-index: 42
Works: 172
Citations: 5,894

Most-cited papers

A molecular perspective of CTLA-4 function.
W. Teft, M. Kirchhof, J. Madrenas
2006Annual Review of Immunology556 citations
Semantic Scholar
The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i‐AAA protease YME1L
T. Wai, S. Saita, H. Nolte, Sebastian Müller +8 more
2016EMBO Reports183 citations Open access
Semantic Scholar
Age-Specific Mortality During the 1918 Influenza Pandemic: Unravelling the Mystery of High Young Adult Mortality
A. Gagnon, Matthew S. Miller, Stacey A. Hallman, R. Bourbeau +3 more
2013PLoS ONE162 citations Open access
Semantic Scholar
Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool
J. García-Castro, C. Trigueros, J. Madrenas, J. Pérez-Simón +2 more
2008Journal of Cellular and Molecular Medicine158 citations Open access
Semantic Scholar
Stomatin-Like Protein 2 Binds Cardiolipin and Regulates Mitochondrial Biogenesis and Function
Darah A. Christie, C. Lemke, Isaac M Elias, Chau A. Luan +6 more
2011Molecular and Cellular Biology146 citations Open access
Semantic Scholar
Toll-like receptor 2 ligands on the staphylococcal cell wall downregulate superantigen-induced T cell activation and prevent toxic shock syndrome
Thu A. Chau, M. McCully, W. Brintnell, G. An +8 more
2009Nature Medicine138 citations
Semantic Scholar
A modulatory interleukin-10 response to staphylococcal peptidoglycan prevents Th1/Th17 adaptive immunity to Staphylococcus aureus.
V. Frodermann, Thu A. Chau, Samar Sayedyahossein, J. Tóth +2 more
2011Journal of Infectious Diseases101 citations
Semantic Scholar
Bacterial Superantigens Bypass Lck-Dependent T Cell Receptor Signaling by Activating a Gα11-Dependent, PLC-β-Mediated Pathway
C. Bueno, C. Lemke, G. Criado, Miren L. Baroja +5 more
200694 citations Open access
Semantic Scholar
Stomatin-Like Protein 2 Is Required for In Vivo Mitochondrial Respiratory Chain Supercomplex Formation and Optimal Cell Function
Panagiotis Mitsopoulos, Yu-Han Chang, T. Wai, Tim König +3 more
2015Molecular and Cellular Biology89 citations Open access
Semantic Scholar
Tumor Suppression by Phospholipase C-β3 via SHP-1-Mediated Dephosphorylation of Stat5
W. Xiao, H. Hong, Y. Kawakami, Y. Kato +15 more
2009Cancer Cell85 citations Open access
Semantic Scholar
High molecular weight polysaccharides are key immunomodulators in North American ginseng extracts: characterization of the ginseng genetic signature in primary human immune cells.
H. R. Lemmon, J. Sham, Chau A. Luan, J. Madrenas
2012Journal of Ethnopharmacology81 citations
Semantic Scholar
Evolving Bacterial Envelopes and Plasticity of TLR2-Dependent Responses: Basic Research and Translational Opportunities
Jun-Bin Li, Dennis Lee, J. Madrenas
2013Frontiers in Immunology69 citations Open access
Semantic Scholar
The helicase senataxin suppresses the antiviral transcriptional response and controls viral biogenesis
Matthew S. Miller, Alexander Rialdi, J. Ho, Micah Tilove +18 more
2015Nature Immunology68 citations Open access
Semantic Scholar
Bacterial superantigens bypass Lck-dependent T cell receptor signaling by activating a Galpha11-dependent, PLC-beta-mediated pathway.
C. Bueno, C. Lemke, G. Criado, M. L. Baroja +5 more
2006Immunity64 citations
Semantic Scholar
TLR2 signalling: At the crossroads of commensalism, invasive infections and toxic shock syndrome by Staphylococcus aureus.
Tina S. Mele, J. Madrenas
2010International Journal of Biochemistry and Cell Biology56 citations
Semantic Scholar
Wilms’ Tumor 1–Associating Protein Regulates the Proliferation of Vascular Smooth Muscle Cells
Theodore W. Small, Zuzana Bolender, C. Bueno, C. O'Neil +7 more
2006Circulation Research56 citations Open access
Semantic Scholar
Stomatin-like Protein 2 Deficiency in T Cells Is Associated with Altered Mitochondrial Respiration and Defective CD4+ T Cell Responses
Darah A. Christie, Panagiotis Mitsopoulos, J. Blagih, S. D. Dunn +4 more
2012Journal of Immunology54 citations Open access
Semantic Scholar
Is Antigenic Sin Always “Original?” Re-examining the Evidence Regarding Circulation of a Human H1 Influenza Virus Immediately Prior to the 1918 Spanish Flu
A. Gagnon, J. Acosta, J. Madrenas, Matthew S. Miller
2015PLoS Pathogens50 citations Open access
Semantic Scholar
Crystal structure of the streptococcal superantigen SpeI and functional role of a novel loop domain in T cell activation by group V superantigens.
Jean-Nicholas P. Brouillard, S. Günther, A. K. Varma, I. Gryski +7 more
2007Journal of Molecular Biology50 citations
Semantic Scholar
MODULATION OF T CELL ACTIVATION BY STOMATIN-LIKE PROTEIN 2
M. Kirchhof, Chau A. Luan, C. Lemke, Santosha Vardhana +7 more
2008Journal of Immunology48 citations Open access
Semantic Scholar
Hierarchical Regulation of CTLA-4 Dimer-Based Lattice Formation and Its Biological Relevance for T Cell Inactivation1
P. Darlington, M. Kirchhof, G. Criado, J. Sondhi +1 more
2005Journal of Immunology48 citations Open access
Semantic Scholar
Intranasal Application of Lactococcus lactis W136 Is Safe in Chronic Rhinosinusitis Patients With Previous Sinus Surgery
L. Endam, S. Alromaih, E. Gonzalez, J. Madrenas +3 more
2020Frontiers in Cellular and Infection Microbiology47 citations Open access
Semantic Scholar
Mitochondrial and Plasma Membrane Pools of Stomatin-Like Protein 2 Coalesce at the Immunological Synapse during T Cell Activation
Darah A. Christie, M. Kirchhof, Santosha Vardhana, Michael Loran Dustin +1 more
2012PLoS ONE44 citations Open access
Semantic Scholar
Pandemic Paradox: Early Life H2N2 Pandemic Influenza Infection Enhanced Susceptibility to Death during the 2009 H1N1 Pandemic
A. Gagnon, Enrique Acosta, Stacey A. Hallman, R. Bourbeau +7 more
2018mBio43 citations Open access
Semantic Scholar
Topical Probiotics as a Therapeutic Alternative for Chronic Rhinosinusitis: A Preclinical Proof of Concept
Joseph S. Schwartz, Adam G. Peres, L. Endam, Benoit Cousineau +2 more
2016American Journal of Rhinology & Allergy41 citations
Semantic Scholar
T cell signalling induced by bacterial superantigens.
C. Bueno, G. Criado, J. McCormick, J. Madrenas
2007Chemical Immunology40 citations
Semantic Scholar
Insertion of Host-Derived Costimulatory Molecules CD80 (B7.1) and CD86 (B7.2) into Human Immunodeficiency Virus Type 1 Affects the Virus Life Cycle
J. Giguère, Salim Bounou, J. Paquette, J. Madrenas +1 more
2004Journal of Virology40 citations Open access
Semantic Scholar
Uncoupling of Pro- and Anti-Inflammatory Properties of Staphylococcus aureus
Adam G. Peres, Camille Stegen, Jun-Bin Li, An-Qi Xu +5 more
2015Infection and Immunity39 citations Open access
Semantic Scholar
The role of IL-10 in microbiome-associated immune modulation and disease tolerance.
B. Levast, Zhigang Li, J. Madrenas
2015Cytokine39 citations
Semantic Scholar
Immunomodulation and Disease Tolerance to Staphylococcus aureus
Zhigang Li, Adam G. Peres, Andreea C Damian, J. Madrenas
2015Pathogens38 citations Open access
Semantic Scholar
Impaired GFR is the most important determinant for FGF-23 increase in chronic kidney disease.
G. Filler, D. Liu, S. Huang, S. Casier +2 more
2011Clinical Biochemistry37 citations
Semantic Scholar
The broad landscape of immune interactions with Staphylococcus aureus: from commensalism to lethal infections.
Adam G. Peres, J. Madrenas
2013Burns36 citations
Semantic Scholar
Structure-Function analysis of the CTLA-4 interaction with PP2A
W. Teft, Thu A. Chau, J. Madrenas
2009BMC Immunology36 citations Open access
Semantic Scholar
Conversion of CTLA-4 from Inhibitor to Activator of T Cells with a Bispecific Tandem Single-Chain Fv Ligand1
J. Madrenas, Chau A. Luan, W. Teft, Paul W. Wu +4 more
2004Journal of Immunology35 citations Open access
Semantic Scholar
Polycationic lipids inhibit the pro-inflammatory response to LPS.
M. León-Ponte, M. Kirchhof, T. Sun, T. Stephens +3 more
2005Immunology Letters31 citations
Semantic Scholar
Fibroblast growth factor-23 and calcium phosphate product in young chronic kidney disease patients: a cross-sectional study
A. Yasin, D. Liu, Chau A. Luan, J. Madrenas +1 more
2013BMC Nephrology30 citations Open access
Semantic Scholar
Down-Regulation of CTLA-4 by HIV-1 Nef Protein
M. El-Far, Catherine Isabelle, N. Chomont, M. Bourbonnière +11 more
2013PLoS ONE30 citations Open access
Semantic Scholar
FcRγ Presence in TCR Complex of Double-Negative T Cells Is Critical for Their Regulatory Function1
C. Thomson, W. Teft, Wen-Hao Chen, B. P. Lee +2 more
2006Journal of Immunology27 citations Open access
Semantic Scholar
Complement regulatory protein Crry/p65‐mediated signaling in T lymphocytes: role of its cytoplasmic domain and partitioning into lipid rafts
A. Jiménez-Periañez, G. Ojeda, G. Criado, Alejandra Sánchez +4 more
2005Journal of Leukocyte Biology27 citations
Semantic Scholar
A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation
Harvey Perez, M. Abdallah, Jose I. Chavira, Angelina S. Norris +13 more
2020bioRxiv25 citations Open access
Semantic Scholar
Stomatin-like protein 2 deficiency results in impaired mitochondrial translation
Panagiotis Mitsopoulos, Orsolya Lapohos, Woranontee Weraarpachai, H. Antonicka +2 more
2017PLoS ONE23 citations Open access
Semantic Scholar
CTLA-4Ig blocks the development and progression of citrullinated fibrinogen-induced arthritis in DR4-transgenic mice.
D. Yue, W. Brintnell, Lisa A. Mannik, Darah A. Christie +5 more
2010Arthritis & Rheumatism22 citations
Semantic Scholar
TAOK3 Regulates Canonical TCR Signaling by Preventing Early SHP-1–Mediated Inactivation of LCK
João V. S. Ormonde, Zhigang Li, Camille Stegen, J. Madrenas
2018Journal of Immunology21 citations Open access
Semantic Scholar
Staphylococcus aureus Downregulates IP-10 Production and Prevents Th1 Cell Recruitment
Zhigang Li, B. Levast, J. Madrenas
2017Journal of Immunology21 citations
Semantic Scholar
RIP2 Is Required for NOD Signaling But Not for Th1 Cell Differentiation and Cellular Allograft Rejection
T. Fairhead, D. Lian, M. McCully, B. Garcia +2 more
2008American Journal of Transplantation21 citations Open access
Semantic Scholar
Characterization of human peritoneal dendritic cell precursors and their involvement in peritonitis
M. McCully, T. Chau, P. Luke, P. Blake +1 more
2005Clinical and Experimental Immunology21 citations Open access
Semantic Scholar
Determinants of Influenza Mortality Trends: Age-Period-Cohort Analysis of Influenza Mortality in the United States, 1959–2016
Enrique Acosta, Stacey A. Hallman, Lisa Y. Dillon, Nadine Ouellette +7 more
2019Demography20 citations Open access
Semantic Scholar
HIV-1 gp120 envelope glycoprotein determinants for cytokine burst in human monocytes
B. Levast, L. Barblu, Mathieu Coutu, Jérémie Prévost +6 more
2017PLoS ONE20 citations Open access
Semantic Scholar
The T Cell Receptor β-Chain Second Complementarity Determining Region Loop (CDR2β) Governs T Cell Activation and Vβ Specificity by Bacterial Superantigens*
A. K. M. Nur-ur Rahman, D. Bonsor, Christine A. Herfst, F. Pollard +6 more
2010Journal of Biological Chemistry20 citations Open access
Semantic Scholar
Molecular Requirements for MHC Class II α-Chain Engagement and Allelic Discrimination by the Bacterial Superantigen Streptococcal Pyrogenic Exotoxin C1
Katherine J. Kasper, Wang Xi, A. K. M. Nur-ur Rahman, M. Nooh +4 more
2008Journal of Immunology20 citations Open access
Semantic Scholar

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