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Xiao-Ping Qi · SciRah

Researcher profile · Semantic Scholar

Xiao-Ping Qi

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Xiao-Ping Qi — researcher profile on SciRah

h-index: 33
Works: 111
Citations: 4,046

Most-cited papers

Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD
S. Mitter, Chun-Juan Song, Xiao-Ping Qi, H. Mao +8 more
2014Autophagy441 citations Open access
Semantic Scholar
Rescue of a mitochondrial deficiency causing Leber hereditary optic neuropathy
J. Guy, Xiao-Ping Qi, Francesco Pallotti, E. Schon +5 more
2002Annals of Neurology275 citations
Semantic Scholar
Mitochondrial Protein Nitration Primes Neurodegeneration in Experimental Autoimmune Encephalomyelitis*
Xiao-Ping Qi, A. Lewin, Liang Sun, W. Hauswirth +1 more
2006Journal of Biological Chemistry149 citations
Semantic Scholar
β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment
Jun Cai, Xiao-Ping Qi, N. Kociok, S. Skosyrski +13 more
2012EMBO Molecular Medicine146 citations Open access
Semantic Scholar
Pathogenic role of diabetes-induced PPAR-α down-regulation in microvascular dysfunction
Yang Hu, Ying Chen, Lexi Ding, Xuemin He +8 more
2013Proceedings of the National Academy of Sciences of the United States of America136 citations Open access
Semantic Scholar
Autophagy in the Retina: A Potential Role in Age-Related Macular Degeneration
S. Mitter, H. Rao, Xiao-Ping Qi, Jun Cai +4 more
2012Advances in Experimental Medicine and Biology136 citations Open access
Semantic Scholar
Suppression of mitochondrial oxidative stress provides long-term neuroprotection in experimental optic neuritis.
Xiao-Ping Qi, A. Lewin, Liang Sun, W. Hauswirth +1 more
2007Investigative Ophthalmology and Visual Science133 citations
Semantic Scholar
The mutant human ND4 subunit of complex I induces optic neuropathy in the mouse.
Xiao-Ping Qi, Liang Sun, A. Lewin, W. Hauswirth +1 more
2007Investigative Ophthalmology and Visual Science122 citations
Semantic Scholar
Oxidative stress-mediated NFκB phosphorylation upregulates p62/SQSTM1 and promotes retinal pigmented epithelial cell survival through increased autophagy
Chun-Juan Song, S. Mitter, Xiao-Ping Qi, Eleni Beli +10 more
2017PLoS ONE106 citations Open access
Semantic Scholar
Optic neuropathy induced by reductions in mitochondrial superoxide dismutase.
Xiao-Ping Qi, A. Lewin, W. Hauswirth, J. Guy
2003Investigative Ophthalmology and Visual Science104 citations Open access
Semantic Scholar
Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology
P. Hu, Rolf Herrmann, A. Bednar, P. Saloupis +8 more
2013Proceedings of the National Academy of Sciences of the United States of America91 citations Open access
Semantic Scholar
Efficiency and Safety of AAV-Mediated Gene Delivery of the Human ND4 Complex I Subunit in the Mouse Visual System
J. Guy, Xiao-Ping Qi, Rajeshwari D. Koilkonda, T. Arguello +5 more
2009Investigative Ophthalmology and Visual Science90 citations Open access
Semantic Scholar
SOD2 gene transfer protects against optic neuropathy induced by deficiency of complex I
Xiao-Ping Qi, A. Lewin, Liang Sun, W. Hauswirth +1 more
2004Annals of Neurology77 citations
Semantic Scholar
Suppression of complex I gene expression induces optic neuropathy
Xiao-Ping Qi, A. Lewin, W. Hauswirth, J. Guy
2003Annals of Neurology75 citations
Semantic Scholar
Use of mitochondrial antioxidant defenses for rescue of cells with a Leber hereditary optic neuropathy-causing mutation.
Xiao-Ping Qi, Liang Sun, W. Hauswirth, A. Lewin +1 more
2007A M A Archives of Ophthalmology68 citations Open access
Semantic Scholar
Targeting the IRE1α/XBP1 and ATF6 arms of the unfolded protein response enhances VEGF blockade to prevent retinal and choroidal neovascularization.
Li Liu, Xiao-Ping Qi, Zhi-Juan Chen, L. Shaw +4 more
2013American Journal of Pathology66 citations Open access
Semantic Scholar
Per2 Mutation Recapitulates the Vascular Phenotype of Diabetes in the Retina and Bone Marrow
A. Bhatwadekar, Yuanqing Yan, Xiao-Ping Qi, J. Thinschmidt +8 more
2012Diabetes63 citations Open access
Semantic Scholar
A novel small molecule ameliorates ocular neovascularisation and synergises with anti-VEGF therapy
Rania S. Sulaiman, Stephanie L Merrigan, Judith L. Quigley, Xiao-Ping Qi +5 more
2016Scientific Reports62 citations Open access
Semantic Scholar
PEDF Regulates Vascular Permeability by a γ-Secretase-Mediated Pathway
Jun Cai, Lin Wu, Xiao-Ping Qi, Sergio Li Calzi +5 more
2011PLoS ONE60 citations Open access
Semantic Scholar
Long-term suppression of neurodegeneration in chronic experimental optic neuritis: antioxidant gene therapy.
Xiao-Ping Qi, Liang Sun, A. Lewin, W. Hauswirth +1 more
2007Investigative Ophthalmology and Visual Science56 citations Open access
Semantic Scholar
Dicer Expression Exhibits a Tissue-Specific Diurnal Pattern That Is Lost during Aging and in Diabetes
Yuanqing Yan, Tatiana E. Salazar, J. Dominguez, D. Nguyen +6 more
2013PLoS ONE53 citations Open access
Semantic Scholar
Ferrochelatase is a therapeutic target for ocular neovascularization
Halesha D. Basavarajappa, Rania S. Sulaiman, Xiao-Ping Qi, Trupti Shetty +13 more
2017EMBO Molecular Medicine51 citations Open access
Semantic Scholar
A Simple Optical Coherence Tomography Quantification Method for Choroidal Neovascularization
Rania S. Sulaiman, Judith L. Quigley, Xiao-Ping Qi, Michael N. O’Hare +3 more
2015Journal of Ocular Pharmacology and Therapeutics46 citations Open access
Semantic Scholar
The 5HT1a Receptor Agonist 8-Oh DPAT Induces Protection from Lipofuscin Accumulation and Oxidative Stress in the Retinal Pigment Epithelium
P. Thampi, H. Rao, S. Mitter, Jun Cai +7 more
2012PLoS ONE42 citations Open access
Semantic Scholar
Diurnal Rhythmicity of Autophagy Is Impaired in the Diabetic Retina
Xiao-Ping Qi, S. Mitter, Yuanqing Yan, J. Busik +2 more
2020Cells41 citations Open access
Semantic Scholar
γ-Secretase and Presenilin Mediate Cleavage and Phosphorylation of Vascular Endothelial Growth Factor Receptor-1
Jun Cai, Zhi-Juan Chen, Qing Ruan, Song Han +6 more
2011Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Placenta Growth Factor-1 Exerts Time-Dependent Stabilization of Adherens Junctions Following VEGF-Induced Vascular Permeability
Jun Cai, Lin Wu, Xiao-Ping Qi, L. Shaw +8 more
2011PLoS ONE38 citations Open access
Semantic Scholar
PPARβ/δ selectively regulates phenotypic features of age-related macular degeneration
Mayur Choudhary, Jin-Dong Ding, Xiao-Ping Qi, M. Boulton +3 more
2016Aging36 citations Open access
Semantic Scholar
Dual gene therapy with extracellular superoxide dismutase and catalase attenuates experimental optic neuritis
Xiao-Ping Qi, W. Hauswirth, J. Guy
2007Molecular Vision34 citations
Semantic Scholar
Progenitor cell combination normalizes retinal vascular development in the oxygen-induced retinopathy (OIR) model.
Sergio Li Calzi, L. Shaw, Leni Moldovan, W. Shelley +7 more
2019JCI Insight30 citations Open access
Semantic Scholar
Free insulin-like growth factor binding protein-3 (IGFBP-3) reduces retinal vascular permeability in association with a reduction of acid sphingomyelinase (ASMase).
Jennifer L. Kielczewski, S. L. Calzi, L. Shaw, Jun Cai +13 more
2011Investigative Ophthalmology and Visual Science28 citations Open access
Semantic Scholar
Chemical proteomics reveals soluble epoxide hydrolase as a therapeutic target for ocular neovascularization
Rania S. Sulaiman, Bomina Park, Sardar Pasha Sheik Pran Babu, Yu-Bing Si +10 more
2017ACS Chemical Biology27 citations Open access
Semantic Scholar
Systemic Injection of RPE65-Programmed Bone Marrow-Derived Cells Prevents Progression of Chronic Retinal Degeneration
Xiao-Ping Qi, S. Pay, Yuanqing Yan, James D. Thomas +4 more
2017Molecular Therapy21 citations Open access
Semantic Scholar
Per 2 Mutation Recapitulates the Vascular Phenotype of Diabetes in the Retina and Bone Marrow
A. Bhatwadekar, Yuanqing Yan, Xiao-Ping Qi, J. Thinschmidt +8 more
201220 citations
Semantic Scholar
Systemic Vascular Transduction by Capsid Mutant Adeno-Associated Virus After Intravenous Injection
D. Lipinski, Christopher A. Reid, Sanford L. Boye, James J. Peterson +4 more
2015Human Gene Therapy17 citations Open access
Semantic Scholar
Potential role for age as a modulator of oral nitrate reductase activity
K. A. Ahmed, Kiyoung Kim, K. Ricart, William J. van der Pol +8 more
2020Nitric oxide16 citations Open access
Semantic Scholar
Sulforaphane recovers cone function in an Nrf2-dependent manner in middle-aged mice undergoing RPE oxidative stress
Xiao-Ping Qi, Dorothy A. Walton, Kendra S. Plafker, M. Boulton +1 more
2022Molecular Vision14 citations
Semantic Scholar
BACE1 Inhibition Increases Susceptibility to Oxidative Stress by Promoting Mitochondrial Damage
Carolina Francelin, S. Mitter, Q. Qian, S. K. Barodia +7 more
2021Antioxidants14 citations Open access
Semantic Scholar
γ-Secretase inhibition of murine choroidal neovascularization is associated with reduction of superoxide and proinflammatory cytokines.
Xiao-Ping Qi, Jun Cai, Qing Ruan, Li Liu +8 more
2012Investigative Ophthalmology and Visual Science14 citations Open access
Semantic Scholar
PRMT5 is a therapeutic target in choroidal neovascularization
Anbukkarasi Muniyandi, Mat Martin, Meng-Yao Sun, Kamakshi L. Sishtla +7 more
2022bioRxiv13 citations Open access
Semantic Scholar
Spatial and temporal VEGF receptor intracellular trafficking in microvascular and macrovascular endothelial cells
J. A. F. Silva, Xiao-Ping Qi, M. Grant, M. Boulton
2021Scientific Reports10 citations Open access
Semantic Scholar
Role of Translational Attenuation in Inherited Retinal Degeneration
Christopher R. Starr, Cyril N A Nyankerh, Xiao-Ping Qi, Yang Hu +4 more
2019Investigative Ophthalmology and Visual Science9 citations Open access
Semantic Scholar
β-secretase 1 overexpression by AAV-mediated gene delivery prevents retina degeneration in a mouse model of age-related macular degeneration
Xiao-Ping Qi, Carolina Francelin, S. Mitter, Sanford L. Boye +4 more
2023Molecular Therapy7 citations Open access
Semantic Scholar
Decreased Expression of Soluble Epoxide Hydrolase Suppresses Murine Choroidal Neovascularization
Bomina Park, S. P. B. Sardar Pasha, Kamakshi L. Sishtla, Gabriella D. Hartman +3 more
2022International Journal of Molecular Sciences4 citations Open access
Semantic Scholar
Supplemental nitrite increases choroidal neovascularization in mice
Xiao-Ping Qi, K. Ricart, K. A. Ahmed, R. Patel +1 more
2021Nitric oxide3 citations Open access
Semantic Scholar
Characterizing temporal and spatial recruitment of systemically administered RPE65-programmed bone marrow-derived cells to the retina in a mouse model of age-related macular degeneration
Carolina Francelin, J. Godoy, Xiao-Ping Qi, J. A. F. Silva +2 more
2021Graefe's Archive for Clinical and Experimental Ophthalmology3 citations Open access
Semantic Scholar
A Non-Canonical Role for β-Secretase in the Retina.
Q. Qian, S. Mitter, S. Pay, Xiao-Ping Qi +3 more
2016Advances in Experimental Medicine and Biology3 citations
Semantic Scholar
AAV-Mediated Sod2 Gene Expression Driven by a Pro-Inflammatory Inducible Promoter: A Novel Method for Gene Therapy of Multiple Sclerosis
L. Sun, Xiao-Ping Qi, W. Hauswirth, J. Guy
20033 citations
Semantic Scholar
Inhibition of β-secretase Results in a Retinal Phenotype Involving Both the Vasculature and the RPE
Xiao-Ping Qi, Jun Cai, Quin Ruan, L. Serneels +6 more
20122 citations
Semantic Scholar
Nitric Oxide Affects the Circadian Rhythmicity of Autophagy in Retinal Microvascular Endothelial Cells
S. Mitter, H. Rao, Jun Cai, P. Thampi +4 more
20102 citations
Semantic Scholar

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