Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

C. L. Heffron · SciRah

Researcher profile · Semantic Scholar

C. L. Heffron

Share profile

C. L. Heffron — researcher profile on SciRah

h-index: 22
Works: 54
Citations: 1,083

Most-cited papers

Pig model mimicking chronic hepatitis E virus infection in immunocompromised patients to assess immune correlates during chronicity
Dianjun Cao, Qian M. Cao, Sakthivel Subramaniam, Danielle M. Yugo +14 more
2017Proceedings of the National Academy of Sciences of the United States of America76 citations Open access
Semantic Scholar
A Novel Pathogenic Mammalian Orthoreovirus from Diarrheic Pigs and Swine Blood Meal in the United States
Athmaram Thimmasandra Narayanappa, Harini Sooryanarain, Jagadeeswaran Deventhiran, Dianjun Cao +10 more
2015mBio73 citations Open access
Semantic Scholar
Risk factors and sources of foodborne hepatitis E virus infection in the United States
Caitlin M. Cossaboom, C. L. Heffron, Dianjun Cao, Danielle M. Yugo +6 more
2016Journal of Medical Virology52 citations
Semantic Scholar
Intra-Abdominal Fat Depots Represent Distinct Immunomodulatory Microenvironments: A Murine Model
C. Cohen, A. Shea, C. L. Heffron, Eva M. Schmelz +1 more
2013PLoS ONE50 citations Open access
Semantic Scholar
Hepatitis E virus infects brain microvascular endothelial cells, crosses the blood–brain barrier, and invades the central nervous system
De-Bin Tian, Wen Li, C. L. Heffron, Bo Wang +6 more
2022Proceedings of the National Academy of Sciences of the United States of America40 citations Open access
Semantic Scholar
Hepatitis E Virus in Pigs from Slaughterhouses, United States, 2017–2019
Harini Sooryanarain, C. L. Heffron, D. Hill, J. Fredericks +4 more
2020Emerging Infectious Diseases39 citations Open access
Semantic Scholar
Replacement of the Hepatitis E Virus ORF3 Protein PxxP Motif with Heterologous Late Domain Motifs Affects Virus Release Via Interaction with TSG101
Scott P. Kenney, Jacquelyn L Wentworth, C. L. Heffron, Xiang-Jin Meng
2015Virology39 citations Open access
Semantic Scholar
The Parity-Associated Microenvironmental Niche in the Omental Fat Band is Refractory to Ovarian Cancer Metastasis
C. Cohen, A. Shea, C. L. Heffron, Eva M. Schmelz +1 more
2013Cancer Prevention Research38 citations Open access
Semantic Scholar
Interleukin-12 Immunomodulation Delays the Onset of Lethal Peritoneal Disease of Ovarian Cancer
C. Cohen, A. Shea, C. L. Heffron, Eva-Maria Schmelz +1 more
2016Journal of Interferon and Cytokine Research36 citations Open access
Semantic Scholar
Evidence for an Unknown Agent Antigenically Related to the Hepatitis E Virus in Dairy Cows in the United States
Danielle M. Yugo, Caitlin M. Cossaboom, C. L. Heffron, Yao-Wei Huang +8 more
2018Journal of Medical Virology30 citations Open access
Semantic Scholar
Vaccination of sows with a dendritic cell-targeted porcine epidemic diarrhea virus S1 protein-based candidate vaccine reduced viral shedding but exacerbated gross pathological lesions in suckling neonatal piglets.
Sakthivel Subramaniam, Danielle M. Yugo, C. L. Heffron, Adam J. Rogers +5 more
2018Journal of General Virology30 citations Open access
Semantic Scholar
Killed whole-genome reduced-bacteria surface-expressed coronavirus fusion peptide vaccines protect against disease in a porcine model
Denicar Lina Nascimento Fabris Maeda, De-Bin Tian, Hanna Yu, N. Dar +10 more
2021Proceedings of the National Academy of Sciences of the United States of America28 citations Open access
Semantic Scholar
Enhancing heterologous protection in pigs vaccinated with chimeric porcine reproductive and respiratory syndrome virus containing the full-length sequences of shuffled structural genes of multiple heterologous strains.
De-Bin Tian, Dianjun Cao, C. L. Heffron, Danielle M. Yugo +7 more
2017Vaccine27 citations Open access
Semantic Scholar
Recombinant Porcine Reproductive and Respiratory Syndrome Virus Expressing Membrane-Bound Interleukin-15 as an Immunomodulatory Adjuvant Enhances NK and γδ T Cell Responses and Confers Heterologous Protection
Qian M. Cao, Yan-Yan Ni, Dianjun Cao, De-Bin Tian +9 more
2018Journal of Virology25 citations Open access
Semantic Scholar
Expression of antigenic epitopes of porcine reproductive and respiratory syndrome virus (PRRSV) in a modified live-attenuated porcine circovirus type 2 (PCV2) vaccine virus (PCV1-2a) as a potential bivalent vaccine against both PCV2 and PRRSV.
Pablo E. Piñeyro, Scott P. Kenney, L. Gimenez-Lirola, C. L. Heffron +3 more
2015Virus Research25 citations
Semantic Scholar
Efficient priming of CD4 T cells by Langerin-expressing dendritic cells targeted with porcine epidemic diarrhea virus spike protein domains in pigs
Sakthivel Subramaniam, Dianjun Cao, De-Bin Tian, Qian M. Cao +12 more
2016Virus Research24 citations Open access
Semantic Scholar
Ribavirin Treatment Failure-Associated Mutation, Y1320H, in the RNA-Dependent RNA Polymerase of Genotype 3 Hepatitis E Virus (HEV) Enhances Virus Replication in a Rabbit HEV Infection Model
Bo Wang, Hassan M. Mahsoub, Wen Li, C. L. Heffron +4 more
2023mBio23 citations Open access
Semantic Scholar
Two mutations in the ORF1 of genotype 1 hepatitis E virus enhance virus replication and may associate with fulminant hepatic failure
Bo Wang, De-Bin Tian, Harini Sooryanarain, Hassan M. Mahsoub +3 more
2022Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
In vivo targeting of porcine reproductive and respiratory syndrome virus antigen through porcine DC-SIGN to dendritic cells elicits antigen-specific CD4T cell immunity in pigs.
Sakthivel Subramaniam, Pablo E. Piñeyro, De-Bin Tian, C. Overend +11 more
2014Vaccine23 citations
Semantic Scholar
Cytotoxic T lymphocyte epitopes identified from a contemporary strain of porcine reproductive and respiratory syndrome virus enhance CD4+CD8+ T, CD8+ T, and γδ T cell responses.
Qian M. Cao, De-Bin Tian, C. L. Heffron, Sakthivel Subramaniam +4 more
2019Virology22 citations Open access
Semantic Scholar
Modulation of Proinflammatory Cytokines in Monocyte-Derived Dendritic Cells by Porcine Reproductive and Respiratory Syndrome Virus Through Interaction with the Porcine Intercellular-Adhesion-Molecule-3-Grabbing Nonintegrin
Pablo E. Piñeyro, Sakthivel Subramaniam, Scott P. Kenney, C. L. Heffron +2 more
2016Viral immunology21 citations
Semantic Scholar
Chimeric porcine reproductive and respiratory syndrome virus containing shuffled multiple envelope genes confers cross-protection in pigs.
De-Bin Tian, Yan-Yan Ni, Lei Zhou, T. Opriessnig +10 more
2015Virology21 citations Open access
Semantic Scholar
The U-Rich Untranslated Region of the Hepatitis E Virus Induces Differential Type I and Type III Interferon Responses in a Host Cell-Dependent Manner
Harini Sooryanarain, C. L. Heffron, Xiang-Jin Meng
2020mBio19 citations Open access
Semantic Scholar
Infection Dynamics of Hepatitis E Virus in Wild-Type and Immunoglobulin Heavy Chain Knockout JH−/− Gnotobiotic Piglets
Danielle M. Yugo, C. L. Heffron, J. Ryu, K. Uh +13 more
2018Journal of Virology19 citations Open access
Semantic Scholar
Virus-like particle vaccine with B-cell epitope from porcine epidemic diarrhea virus (PEDV) incorporated into hepatitis B virus core capsid provides clinical alleviation against PEDV in neonatal piglets through lactogenic immunity.
Yi Lu, S. Clark-Deener, Frank Gillam, C. L. Heffron +9 more
2020Vaccine17 citations
Semantic Scholar
Prevalence of the Novel Torque Teno Sus Virus Species k2b from Pigs in the United States and Lack of Association with Post‐Weaning Multisystemic Wasting Syndrome or Mulberry Heart Disease
Adam J. Rogers, Yao-Wei Huang, C. L. Heffron, T. Opriessnig +2 more
2017Transboundary and Emerging Diseases15 citations Open access
Semantic Scholar
Evaluation of the use of non-pathogenic porcine circovirus type 1 as a vaccine delivery virus vector to express antigenic epitopes of porcine reproductive and respiratory syndrome virus.
Pablo E. Piñeyro, Scott P. Kenney, L. Gimenez-Lirola, Tanja Opriessnig +3 more
2016Virus Research15 citations Open access
Semantic Scholar
Fetal Loss in Pregnant Rabbits Infected with Genotype 3 Hepatitis E Virus Is Associated with Altered Inflammatory Responses, Enhanced Virus Replication, and Extrahepatic Virus Dissemination with Positive Correlations with Increased Estradiol Level
Hassan M. Mahsoub, C. L. Heffron, A. Hassebroek, Harini Sooryanarain +5 more
2023mBio14 citations Open access
Semantic Scholar
Modulation of SOCS3 Levels via STAT3 and Estrogen-ERαp66 Signaling during Hepatitis E Virus Replication in Hepatocellular Carcinoma Cells
Harini Sooryanarain, C. L. Heffron, Hassan M. Mahsoub, A. Hassebroek +4 more
2022Journal of Virology14 citations Open access
Semantic Scholar
Regulation of Cytoskeleton Organization by Sphingosine in a Mouse Cell Model of Progressive Ovarian Cancer
Amy L. Creekmore, C. L. Heffron, B. Brayfield, P. C. Roberts +1 more
2013Biomolecules14 citations Open access
Semantic Scholar
Membrane-bound IL-12 and IL-23 serve as potent mucosal adjuvants when co-presented on whole inactivated influenza vaccines
Tila Khan, C. L. Heffron, K. High, P. Roberts
2014Virology Journal13 citations Open access
Semantic Scholar
Obesity modulates the cellular and molecular microenvironment in the peritoneal cavity: implication for ovarian cancer risk
A. Shea, C. L. Heffron, Joseph P. Grieco, P. C. Roberts +1 more
2024Frontiers in Immunology11 citations Open access
Semantic Scholar
A hepatitis B virus core antigen-based virus-like particle vaccine expressing SARS-CoV-2 B and T cell epitopes induces epitope-specific humoral and cell-mediated immune responses but confers limited protection against SARS-CoV-2 infection
Anna M. Hassebroek, Harini Sooryanarain, C. L. Heffron, Seth A. Hawks +13 more
2023Journal of Medical Virology11 citations Open access
Semantic Scholar
Dissecting the potential role of hepatitis E virus ORF1 nonstructural gene in cross‐species infection by using intergenotypic chimeric viruses
De-Bin Tian, Danielle M. Yugo, Scott P. Kenney, C. L. Heffron +5 more
2020Journal of Medical Virology11 citations Open access
Semantic Scholar
Antiviral resistance and barrier integrity at the maternal-fetal interface restrict hepatitis E virus from crossing the placental barrier
De-Bin Tian, Wen Li, C. L. Heffron, Hassan M. Mahsoub +3 more
2025Proceedings of the National Academy of Sciences of the United States of America8 citations Open access
Semantic Scholar
Tailored Vaccines Targeting the Elderly Using Whole Inactivated Influenza Vaccines Bearing Cytokine Immunomodulators
Tila Khan, C. L. Heffron, K. High, P. Roberts
2014Journal of Interferon and Cytokine Research8 citations Open access
Semantic Scholar
Construction and efficacy evaluation of novel swine leukocyte antigen (SLA) class I and class II allele-specific poly-T cell epitope vaccines against porcine reproductive and respiratory syndrome virus.
De-Bin Tian, Sakthivel Subramaniam, C. L. Heffron, Hassan M. Mahsoub +8 more
2020Journal of General Virology7 citations Open access
Semantic Scholar
Evaluation of the pathogenicity of mammalian orthoreovirus type 3 (MRV3) in germ-free gnotobiotic pigs and of the efficacy of an inactivated vaccine against MRV3 infection in neonatal conventional piglets.
Dianjun Cao, Harini Sooryanarain, Danielle M. Yugo, De-Bin Tian +10 more
2018Veterinary Microbiology7 citations
Semantic Scholar
Phosphorylation of Ser711 residue in the hypervariable region of zoonotic genotype 3 hepatitis E virus is important for virus replication
Bo Wang, Sakthivel Subramaniam, De-Bin Tian, Hassan M. Mahsoub +2 more
2024mBio6 citations Open access
Semantic Scholar
Membrane-bound IL-12 and IL-23 serve as potent mucosal adjuvants when co-presented on whole inactivated influenza vaccines
Tila Khan, C. L. Heffron, K. High, P. C. Roberts
2014Virology Journal5 citations Open access
Semantic Scholar
CD8+ lymphocytes but not B lymphocytes are required for protection against chronic hepatitis E virus infection in chickens
Eda Rogers, M. Todd, F. Pierson, Scott P. Kenney +13 more
2019Journal of Medical Virology3 citations Open access
Semantic Scholar
Erratum for Mahsoub et al., “Fetal Loss in Pregnant Rabbits Infected with Genotype 3 Hepatitis E Virus Is Associated with Altered Inflammatory Responses, Enhanced Virus Replication, and Extrahepatic Virus Dissemination with Positive Correlations with Increased Estradiol Level”
Hassan M. Mahsoub, C. L. Heffron, A. Hassebroek, Harini Sooryanarain +5 more
2023mBio1 citations Open access
Semantic Scholar
Isolation of Peripheral Blood CD8 T Cells Specific to Porcine Reproductive and Respiratory Syndrome Virus Utilizing Porcine CD137 Activation Marker
Sakthivel Subramaniam, C. Overend, Danielle M. Yugo, C. L. Heffron +6 more
2018Viral immunology1 citations
Semantic Scholar
RNA transcripts of full-length cDNA clones of rabbit hepatitis E virus are infectious in rabbits.
Caitlin M. Cossaboom, Yao-Wei Huang, Danielle M. Yugo, Scott P. Kenney +5 more
2014Journal of General Virology1 citations
Semantic Scholar
Retraction. RNA transcripts of full-length cDNA clones of rabbit hepatitis E virus are infectious in rabbits.
Caitlin M. Cossaboom, Yao-Wei Huang, Danielle M. Yugo, Scott P. Kenney +5 more
2015Journal of General Virology0 citations Open access
Semantic Scholar
Abstract 799: Obesity-associated modulation of the immune microenvironment of the omental fat band during peritoneal seeding of ovarian cancer
Courie Cohen, C. L. Heffron, Eva M. Schmelz, P. C. Roberts
20110 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

Xiang-Jin Meng×33
Invite
Xiang-Jin Meng — researcher profile on SciRah
De-Bin Tian×23
Invite
De-Bin Tian — researcher profile on SciRah
T. LeRoith×15
Invite
T. LeRoith — researcher profile on SciRah
Harini Sooryanarain×15
Invite
Harini Sooryanarain — researcher profile on SciRah

Scott P. Kenney

×14

Invite

Scott P. Kenney — researcher profile on SciRah

Sakthivel Subramaniam×12

Invite

Sakthivel Subramaniam — researcher profile on SciRah

Danielle M. Yugo×11

Invite

Danielle M. Yugo — researcher profile on SciRah

Shannon R. Matzinger×11

Invite

Shannon R. Matzinger — researcher profile on SciRah

Invite

Bo Wang — researcher profile on SciRah

Dianjun Cao×10

Invite

Dianjun Cao — researcher profile on SciRah

Adam J. Rogers×9

Invite

Adam J. Rogers — researcher profile on SciRah

Invite

C. Overend — researcher profile on SciRah