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N. Perkins · SciRah

Researcher profile · Semantic Scholar

N. Perkins

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N. Perkins — researcher profile on SciRah

h-index: 61
Works: 163
Citations: 18K

Most-cited papers

Integrating cell-signalling pathways with NF-κB and IKK function
N. Perkins
2007Nature reviews. Molecular cell biology1,791 citations Open access
Semantic Scholar
Integrating cell-signalling pathways with NF-kappaB and IKK function.
N. Perkins
2007Nature reviews. Molecular cell biology1,093 citations
Semantic Scholar
The diverse and complex roles of NF-κB subunits in cancer
N. Perkins
2012Nature Reviews. Cancer808 citations
Semantic Scholar
Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway
N. Perkins
2006Oncogene704 citations Open access
Semantic Scholar
Transcriptional profiling of the LPS induced NF-κB response in macrophages
O. Sharif, Viacheslav N Bolshakov, S. Raines, P. Newham +1 more
2007BMC Immunology510 citations Open access
Semantic Scholar
Good cop, bad cop: the different faces of NF-κB
N. Perkins, T. Gilmore
2006Cell Death and Differentiation487 citations Open access
Semantic Scholar
SIRT1 Deacetylation and Repression of p300 Involves Lysine Residues 1020/1024 within the Cell Cycle Regulatory Domain 1*
Toula Bouras, M. Fu, A. Sauve, Fang Wang +5 more
2005Journal of Biological Chemistry363 citations Open access
Semantic Scholar
The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor
Gaynor J. Bates, Samantha M. Nicol, Brian J. Wilson, Anne-Marie F. Jacobs +6 more
2005EMBO Journal251 citations Open access
Semantic Scholar
Good cop, bad cop: the different faces of NF-kappaB.
N. Perkins, T. Gilmore
2006Cell Death and Differentiation249 citations
Semantic Scholar
Regulation of NF‐κB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor
S. Rocha, M. Garrett, K. Campbell, Katie Schumm +1 more
2005EMBO Journal193 citations Open access
Semantic Scholar
Endothelial–cell FAK targeting sensitizes tumours to DNA–damaging therapy
Bernardo Tavora, L. Reynolds, Silvia A. A. Batista, F. Demircioglu +12 more
2014Nature161 citations Open access
Semantic Scholar
Regulation of p53 tumour suppressor target gene expression by the p52 NF‐κB subunit
Katie Schumm, S. Rocha, J. Caamaño, N. Perkins
2006EMBO Journal156 citations Open access
Semantic Scholar
Nuclear factor-κB, p53, and mitochondria: regulation of cellular metabolism and the Warburg effect.
Renée F. Johnson, N. Perkins
2012TIBS -Trends in Biochemical Sciences. Regular ed147 citations
Semantic Scholar
Regulation of NF-kappaB function.
K. Campbell, N. Perkins
2006Biochemical Society Symposium135 citations Open access
Semantic Scholar
p53-dependent repression of polo-like kinase-1 (PLK1)
L. McKenzie, S. King, Lynnette Marcar, Samantha M. Nicol +7 more
2010Cell Cycle127 citations Open access
Semantic Scholar
The STAT3 oncogene as a predictive marker of drug resistance.
Benjamin P. Barre, Arnaud M. Vigneron, N. Perkins, I. Roninson +2 more
2007Trends in Molecular Medicine127 citations
Semantic Scholar
Regulation of cyclin D1 gene expression.
Ini-Isabée Witzel, L. Koh, N. Perkins
2010Biochemical Society Transactions126 citations Open access
Semantic Scholar
p53-dependent regulation of mitochondrial energy production by the RelA subunit of NF-κB
Renée F. Johnson, Ini-Isabée Witzel, N. Perkins
2011Cancer Research124 citations Open access
Semantic Scholar
Age-associated mitochondrial DNA mutations cause metabolic remodelling that contributes to accelerated intestinal tumorigenesis
Anna L. M. Smith, Julia Whitehall, Carla Bradshaw, D. Gay +28 more
2020Nature Cancer119 citations Open access
Semantic Scholar
Regulation of p53 and Rb Links the Alternative NF-κB Pathway to EZH2 Expression and Cell Senescence
Alessio Iannetti, Adeline C. Ledoux, S. Tudhope, H. Sellier +9 more
2014PLoS Genetics108 citations Open access
Semantic Scholar
Regulation of Cyclin D1 RNA stability by SNIP1
C. Bracken, S. Wall, Benjamin P. Barre, K. Panov +2 more
2008Cancer Research108 citations Open access
Semantic Scholar
NF-κB and the cell cycle.
Adeline C. Ledoux, N. Perkins
2014Biochemical Society Transactions107 citations
Semantic Scholar
Cyclin D1 Represses p300 Transactivation through a Cyclin-dependent Kinase-independent Mechanism*
M. Fu, Chen-Guang Wang, Mahadev Rao, Xiaofang Wu +13 more
2005Journal of Biological Chemistry97 citations Open access
Semantic Scholar
Cisplatin mimics ARF tumor suppressor regulation of RelA (p65) nuclear factor-kappaB transactivation.
K. Campbell, James Witty, S. Rocha, N. Perkins
2006Cancer Research95 citations Open access
Semantic Scholar
p53 and NF-?B Crosstalk: IKKa Tips the Balance
V. Tergaonkar, N. Perkins
200787 citations Open access
Semantic Scholar
The Skp2 promoter integrates signaling through the NF-kappaB, p53, and Akt/GSK3beta pathways to regulate autophagy and apoptosis.
Benjamin P. Barre, N. Perkins
2010Molecules and Cells84 citations Open access
Semantic Scholar
Regulation of the RelA (p65) transactivation domain.
John M O'Shea, N. Perkins
2008Biochemical Society Transactions77 citations
Semantic Scholar
Retracted: A cell cycle regulatory network controlling NF‐κB subunit activity and function
Benjamin P. Barre, N. Perkins
2007EMBO Journal77 citations Open access
Semantic Scholar
Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis.
Andrea J. White, D. Carragher, S. Parnell, A. Msaki +5 more
2007Blood76 citations Open access
Semantic Scholar
A238L Inhibits NF-ATc2, NF-κB, and c-Jun Activation through a Novel Mechanism Involving Protein Kinase C-θ-Mediated Up-Regulation of the Amino-Terminal Transactivation Domain of p3001
A. G. Granja, N. Perkins, Y. Revilla
2008Journal of Immunology67 citations Open access
Semantic Scholar
SNIP1 is a candidate modifier of the transcriptional activity of c-Myc on E box-dependent target genes.
M. Fujii, L. Lyakh, C. Bracken, J. Fukuoka +11 more
2006Molecules and Cells64 citations Open access
Semantic Scholar
c-Rel and its many roles in cancer: an old story with new twists
Jill E. Hunter, J. Leslie, N. Perkins
2016British Journal of Cancer61 citations Open access
Semantic Scholar
The clinical development candidate CCT245737 is an orally active CHK1 inhibitor with preclinical activity in RAS mutant NSCLC and Eμ-MYC driven B-cell lymphoma
M. Walton, Paul D. Eve, A. Hayes, A. Henley +18 more
2015OncoTarget61 citations Open access
Semantic Scholar
Differential Regulation of c-Jun-dependent Transcription by SUMO-specific Proteases*
Jinke Cheng, N. Perkins, Edward T. H. Yeh
2005Journal of Biological Chemistry61 citations Open access
Semantic Scholar
Proenkephalin assists stress-activated apoptosis through transcriptional repression of NF-κB- and p53-regulated gene targets
Niall McTavish, L. Copeland, M. Saville, N. Perkins +1 more
2007Cell Death and Differentiation48 citations Open access
Semantic Scholar
Differential regulation of NF-κB activation and function by topoisomerase II inhibitors
K. Campbell, John M O'Shea, N. Perkins
2006BMC Cancer48 citations Open access
Semantic Scholar
Identification and Functional Characterization of FMN2, a Regulator of the Cyclin-Dependent Kinase Inhibitor p21
Kayo Yamada, M. Ono, N. Perkins, S. Rocha +1 more
2013Molecules and Cells46 citations Open access
Semantic Scholar
Inhibition of RelA-Ser536 Phosphorylation by a Competing Peptide Reduces Mouse Liver Fibrosis Without Blocking the Innate Immune Response
A. Moles, A. M. Sánchez, P. Banks, Lindsay B. Murphy +10 more
2013Hepatology44 citations Open access
Semantic Scholar
A238L inhibits NF-ATc2, NF-kappa B, and c-Jun activation through a novel mechanism involving protein kinase C-theta-mediated up-regulation of the amino-terminal transactivation domain of p300.
A. G. Granja, N. Perkins, Y. Revilla
2008Journal of Immunology44 citations
Semantic Scholar
p53 and NF-kappaB crosstalk: IKKalpha tips the balance.
V. Tergaonkar, N. Perkins
2007Molecules and Cells44 citations
Semantic Scholar
The role of RelA (p65) threonine 505 phosphorylation in the regulation of cell growth, survival, and migration
A. Msaki, A. M. Sánchez, L. Koh, Benjamin P. Barre +3 more
2011Molecular Biology of the Cell43 citations Open access
Semantic Scholar
Cysteine 38 holds the key to NF-κB activation.
N. Perkins
2012Molecules and Cells41 citations Open access
Semantic Scholar
IEX-1 directly interferes with RelA/p65 dependent transactivation and regulation of apoptosis.
A. Arlt, P. Rosenstiel, M. Kruse, Frauke Grohmann +5 more
2008Biochimica et Biophysica Acta40 citations Open access
Semantic Scholar
Identification of new mechanisms of cellular response to chemotherapy by tracking changes in post-translational modifications by ubiquitin and ubiquitin-like proteins.
T. Bonacci, S. Audebert, L. Camoin, Émilie Baudelet +7 more
2014Journal of Proteome Research37 citations Open access
Semantic Scholar
Regulation of the RelA ( p 65 ) transactivation domain
John M O'Shea, N. Perkins
200837 citations
Semantic Scholar
A RelA(p65) Thr505 phospho-site mutation reveals an important mechanism regulating NF-κB-dependent liver regeneration and cancer
A. Moles, Jacqueline A. Butterworth, A. M. Sánchez, Jill E. Hunter +7 more
2016Oncogene35 citations Open access
Semantic Scholar
BAG-1 interacts with the p50-p50 homodimeric NF-κB complex: implications for colorectal carcinogenesis
Samantha L. Southern, T. J. Collard, B. Urban, V. Skeen +7 more
2011Oncogene35 citations Open access
Semantic Scholar
High-throughput sequencing identifies STAT3 as the DNA-associated factor for p53-NF-κB-complex-dependent gene expression in human heart failure
M. Choy, Mehregan Movassagh, Lee Siggens, A. Vujic +7 more
2010Genome Medicine34 citations Open access
Semantic Scholar
NFκB regulates expression of Polo-like kinase 4
Adeline C. Ledoux, H. Sellier, Katie Gillies, Alessio Iannetti +2 more
2013Cell Cycle33 citations Open access
Semantic Scholar
ARF the Integrator: Linking NF-?B, p53 and Checkpoint Kinases
S. Rocha, N. Perkins
2005Cell Cycle33 citations Open access
Semantic Scholar

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Adeline C. Ledoux×4
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J. Leslie — researcher profile on SciRah

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