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D. Howells · SciRah

Researcher profile · Semantic Scholar

D. Howells

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D. Howells — researcher profile on SciRah

h-index: 54
Works: 177
Citations: 27K

Most-cited papers

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research*
Nathalie Percie du Sert, Viki Hurst, A. Ahluwalia, S. Alam +24 more
2020British Journal of Pharmacology8,973 citations Open access
Semantic Scholar
The ARRIVE guidelines 2.0: updated guidelines for reporting animal research
Nathalie Percie du Sert, Viki Hurst, A. Ahluwalia, S. Alam +24 more
2020Journal of Physiology1,319 citations Open access
Semantic Scholar
A call for transparent reporting to optimize the predictive value of preclinical research
Story C. Landis, S. Amara, K. Asadullah, Chris P. Austin +32 more
2012Nature1,177 citations Open access
Semantic Scholar
Reporting animal research: Explanation and Elaboration for the ARRIVE guidelines 2019
Nathalie Percie du Sert, A. Ahluwalia, S. Alam, Marc T. Avey +23 more
2019bioRxiv753 citations Open access
Semantic Scholar
Meta-analysis of data from animal studies: a practical guide.
H. Vesterinen, E. Sena, K. Egan, T. Hirst +5 more
2014Journal of Neuroscience Methods380 citations Open access
Semantic Scholar
Pericytes and Neurovascular Function in the Healthy and Diseased Brain
Lachlan S. Brown, Catherine G. Foster, J. Courtney, Natalie E. King +2 more
2019Frontiers in Cellular Neuroscience347 citations Open access
Semantic Scholar
Risk of Bias in Reports of In Vivo Research: A Focus for Improvement
M. Macleod, A. Lawson McLean, Aikaterini Kyriakopoulou, S. Serghiou +15 more
2015PLoS Biology305 citations Open access
Semantic Scholar
Evaluation of Excess Significance Bias in Animal Studies of Neurological Diseases
K. Tsilidis, O. Panagiotou, E. Sena, E. Aretouli +5 more
2013PLoS Biology275 citations Open access
Semantic Scholar
Systematic Reviews and Meta-Analysis of Preclinical Studies: Why Perform Them and How to Appraise Them Critically
E. Sena, G. Currie, S. McCann, M. Macleod +1 more
2014Journal of Cerebral Blood Flow and Metabolism241 citations Open access
Semantic Scholar
A Multicentre, Randomized, Double-Blinded, Placebo-Controlled Phase III Study to Investigate Extending the Time for Thrombolysis in Emergency Neurological Deficits (EXTEND)
Henry K. Ma, M. Parsons, S. Christensen, B. Campbell +25 more
2012International Journal of Stroke208 citations Open access
Semantic Scholar
The ARRIVE guidelines 2019: updated guidelines for reporting animal research
Nathalie Percie du Sert, Viki Hurst, A. Ahluwalia, S. Alam +22 more
2019bioRxiv193 citations Open access
Semantic Scholar
Standardized mean differences cause funnel plot distortion in publication bias assessments
P. Zwetsloot, M. van der Naald, E. Sena, D. Howells +5 more
2017eLife181 citations Open access
Semantic Scholar
Fish Oil Diet Associated with Acute Reperfusion Related Hemorrhage, and with Reduced Stroke-Related Sickness Behaviors and Motor Impairment
M. Pascoe, D. Howells, D. Crewther, N. Constantinou +5 more
2014Frontiers in Neurology172 citations Open access
Semantic Scholar
How to make better use of thrombolytic therapy in acute ischemic stroke
G. Donnan, S. Davis, M. Parsons, Henry Ma +2 more
2011Nature Reviews Neurology150 citations
Semantic Scholar
Stem Cell-Based Therapy for Experimental Stroke: A Systematic Review and Meta-Analysis
J. Lees, E. Sena, K. Egan, A. Antonić +3 more
2012International Journal of Stroke133 citations
Semantic Scholar
Stem Cell Transplantation in Traumatic Spinal Cord Injury: A Systematic Review and Meta-Analysis of Animal Studies
A. Antonić, E. Sena, J. Lees, T. E. Wills +4 more
2013PLoS Biology128 citations Open access
Semantic Scholar
Acute Stroke Biomarkers: Are We There Yet?
M. Dagonnier, G. Donnan, S. Davis, H. Dewey +1 more
2021Frontiers in Neurology124 citations Open access
Semantic Scholar
Bringing rigour to translational medicine
D. Howells, E. Sena, M. Macleod
2014Nature Reviews Neurology118 citations Open access
Semantic Scholar
A Concerted Appeal for International Cooperation in Preclinical Stroke Research
U. Dirnagl, Antoine M. Hakim, M. Macleod, M. Fisher +8 more
2013Stroke110 citations Open access
Semantic Scholar
Meta-Analysis of Pre-Clinical Studies of Early Decompression in Acute Spinal Cord Injury: A Battle of Time and Pressure
P. Batchelor, T. E. Wills, Peta Skeers, Camila R. Battistuzzo +3 more
2013PLoS ONE104 citations Open access
Semantic Scholar
Olfactory Ensheathing Cell Transplantation in Experimental Spinal Cord Injury: Effect size and Reporting Bias of 62 Experimental Treatments: A Systematic Review and Meta-Analysis
Ralf Watzlawick, Julian Rind, E. Sena, B. Brommer +6 more
2016PLoS Biology101 citations Open access
Semantic Scholar
Effect and reporting bias of RhoA/ROCK-blockade intervention on locomotor recovery after spinal cord injury: a systematic review and meta-analysis.
R. Watzlawick, E. Sena, U. Dirnagl, B. Brommer +4 more
2014JAMA Neurology92 citations
Semantic Scholar
Did a change in Nature journals’ editorial policy for life sciences research improve reporting?
M. Macleod, E. Sena, D. Howells, V. Kiermer +39 more
2019BMJ Open Science75 citations Open access
Semantic Scholar
Efficacy of Antidepressants in Animal Models of Ischemic Stroke: A Systematic Review and Meta-Analysis
S. McCann, C. Irvine, G. Mead, E. Sena +4 more
2014Stroke71 citations Open access
Semantic Scholar
Circadian Biology and Stroke.
Eng H. Lo, G. Albers, M. Dichgans, G. Donnan +21 more
2021Stroke69 citations Open access
Semantic Scholar
Exercise Reduces Infarct Volume and Facilitates Neurobehavioral Recovery
K. Egan, H. Janssen, E. Sena, L. Longley +6 more
2014Neurorehabilitation and Neural Repair59 citations
Semantic Scholar
Improving the Efficiency of the Development of Drugs for Stroke
D. Howells, E. Sena, Victoria E. O'Collins, M. Macleod
2012International Journal of Stroke54 citations Open access
Semantic Scholar
Evaluation of Combination Therapy in Animal Models of Cerebral Ischemia
Victoria E. O'Collins, M. Macleod, G. Donnan, D. Howells
2012Journal of Cerebral Blood Flow and Metabolism54 citations Open access
Semantic Scholar
Evolution of ischemic damage and behavioural deficit over 6 months after MCAo in the rat: Selecting the optimal outcomes and statistical power for multi-centre preclinical trials
Sarah S. J. Rewell, L. Churilov, T. K. Sidon, Elena Aleksoska +3 more
2017PLoS ONE53 citations Open access
Semantic Scholar
Revision of the ARRIVE guidelines: rationale and scope
N. P. du Sert, Viki Hurst, A. Ahluwalia, S. Alam +22 more
2018BMJ Open Science47 citations Open access
Semantic Scholar
The Influence of Stroke Risk Factors and Comorbidities on Assessment of Stroke Therapies in Humans and Animals
Sandeep Ankolekar, Sarah S. J. Rewell, D. Howells, P. Bath
2012International Journal of Stroke44 citations Open access
Semantic Scholar
Human Ischaemic Cascade Studies Using SH-SY5Y Cells: a Systematic Review and Meta-Analysis
Ye Liu, Emma D. Eaton, T. E. Wills, S. McCann +2 more
2018Translational Stroke Research38 citations Open access
Semantic Scholar
Hypertension and Experimental Stroke Therapies
Victoria E. O'Collins, G. Donnan, M. Macleod, D. Howells
2013Journal of Cerebral Blood Flow and Metabolism38 citations Open access
Semantic Scholar
A Pathway Proteomic Profile of Ischemic Stroke Survivors Reveals Innate Immune Dysfunction in Association with Mild Symptoms of Depression – A Pilot Study
Vinh A. Nguyen, Leeanne M. Carey, Loretta Giummarra, P. Faou +8 more
2016Frontiers in Neurology37 citations Open access
Semantic Scholar
The effect of rapamycin treatment on cerebral ischemia: A systematic review and meta-analysis of animal model studies
Daniel J. Beard, G. Hadley, N. Thurley, D. Howells +2 more
2018International Journal of Stroke34 citations Open access
Semantic Scholar
Risk of bias reporting in the recent animal focal cerebral ischaemia literature
Z. Bahor, Jing Liao, M. Macleod, A. Bannach-Brown +8 more
2017Clinical science34 citations Open access
Semantic Scholar
A combined pre-clinical meta-analysis and randomized confirmatory trial approach to improve data validity for therapeutic target validation
Pamela W. M. Kleikers, C. Hooijmans, E. Göb, F. Langhauser +6 more
2015Scientific Reports34 citations Open access
Semantic Scholar
Differences in Fatigue-like Behavior in the Lipopolysaccharide and Poly I:C Inflammatory Animal Models.
Catherine G. Foster, Lila M Landowski, Brad A. Sutherland, D. Howells
2021Physiology and Behavior33 citations Open access
Semantic Scholar
Outcome heterogeneity and bias in acute experimental spinal cord injury
Ralf Watzlawick, A. Antonić, E. Sena, M. Kopp +5 more
2019Neurology33 citations Open access
Semantic Scholar
Applications of Nanotechnology in the Diagnosis and Therapy of Stroke
Lila M Landowski, B. Niego, Brad A. Sutherland, C. Hagemeyer +1 more
2019Seminars in Thrombosis and Hemostasis31 citations Open access
Semantic Scholar
NXY-059, a Failed Stroke Neuroprotectant, Offers No Protection to Stem Cell-Derived Human Neurons.
A. Antonić, M. Dottori, M. Macleod, G. Donnan +1 more
2018Journal of Stroke & Cerebrovascular Diseases30 citations Open access
Semantic Scholar
Correction: Risk of Bias in Reports of In Vivo Research: A Focus for Improvement
M. Macleod, A. Lawson McLean, Aikaterini Kyriakopoulou, S. Serghiou +15 more
2015PLoS Biology29 citations Open access
Semantic Scholar
Intracanal Pressure in Compressive Spinal Cord Injury: Reduction with Hypothermia
P. Batchelor, Nicole F Kerr, Amy M Gatt, Susan F. Cox +4 more
2011Journal of Neurotrauma28 citations
Semantic Scholar
Hypothermia protects human neurons
A. Antonić, M. Dottori, Jessie Leung, K. Sidon +4 more
2014International Journal of Stroke27 citations Open access
Semantic Scholar
STroke imAging pRevention and Treatment (START): A Longitudinal Stroke Cohort Study: Clinical Trials Protocol
L. Carey, Sheila G. Crewther, O. Salvado, Thomas Lindén +40 more
2015International Journal of Stroke26 citations Open access
Semantic Scholar
A Novel Population of α-Smooth Muscle Actin-Positive Cells Activated in a Rat Model of Stroke: An Analysis of the Spatio-Temporal Distribution in Response to Ischemia
V. Sharma, T. Ling, Sarah S. J. Rewell, D. Hare +3 more
2012Journal of Cerebral Blood Flow and Metabolism26 citations Open access
Semantic Scholar
Evidence-based translational medicine.
D. Howells, M. Macleod
2013Stroke25 citations Open access
Semantic Scholar
‘Salvaged’ Stroke Ischaemic Penumbra Shows Significant Injury: Studies with the Hypoxia Tracer FMISO
N. Spratt, G. Donnan, D. McLeod, D. Howells
2011Journal of Cerebral Blood Flow and Metabolism21 citations Open access
Semantic Scholar
Conventional protein kinase Cβ‐mediated phosphorylation inhibits collapsin response‐mediated protein 2 proteolysis and alleviates ischemic injury in cultured cortical neurons and ischemic stroke‐induced mice
Xuan Yang, Xinxin Zhang, Yun Li, Song Han +3 more
2016Journal of Neurochemistry18 citations Open access
Semantic Scholar
Detection of activated platelets in a mouse model of carotid artery thrombosis with 18 F-labeled single-chain antibodies.
K. Ardipradja, S. Yeoh, K. Alt, G. O'Keefe +6 more
2014Nuclear Medicine and Biology18 citations
Semantic Scholar

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