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A. Hobolth · SciRah

Researcher profile · Semantic Scholar

A. Hobolth

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A. Hobolth — researcher profile on SciRah

h-index: 31
Works: 111
Citations: 6,086

Most-cited papers

Great ape genetic diversity and population history
J. Prado-Martinez, P. Sudmant, J. Kidd, Heng Li +71 more
2013Nature870 citations Open access
Semantic Scholar
Insights into hominid evolution from the gorilla genome sequence
A. Scally, J. Dutheil, L. Hillier, Gregory E. Jordan +67 more
2012Nature730 citations Open access
Semantic Scholar
Comparative and demographic analysis of orangutan genomes
Devin P. Locke, L. Hillier, W. Warren, K. Worley +98 more
2011Nature599 citations Open access
Semantic Scholar
The bonobo genome compared with the chimpanzee and human genomes
Kay Prüfer, K. Munch, I. Hellmann, K. Akagi +37 more
2012Nature529 citations Open access
Semantic Scholar
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
E. Rheinbay, M. Nielsen, F. Abascal, J. Wala +90 more
2020Nature525 citations Open access
Semantic Scholar
Genomic Relationships and Speciation Times of Human, Chimpanzee, and Gorilla Inferred from a Coalescent Hidden Markov Model
A. Hobolth, O. F. Christensen, T. Mailund, M. Schierup
2006PLoS Genetics335 citations Open access
Semantic Scholar
Incomplete lineage sorting patterns among human, chimpanzee, and orangutan suggest recent orangutan speciation and widespread selection.
A. Hobolth, J. Dutheil, J. Hawks, M. Schierup +1 more
2011Genome Research223 citations Open access
Semantic Scholar
Integrative pathway enrichment analysis of multivariate omics data
M. Paczkowska, J. Barenboim, N. Sintupisut, Natalie S. Fox +129 more
2020Nature Communications212 citations Open access
Semantic Scholar
Detecting archaic introgression using an unadmixed outgroup
Laurits Skov, Ruoyun Hui, Vladimir Shchur, A. Hobolth +3 more
2018PLoS Genetics124 citations Open access
Semantic Scholar
Ancestral Population Genomics: The Coalescent Hidden Markov Model Approach
J. Dutheil, G. Ganapathy, A. Hobolth, T. Mailund +2 more
2009Genetics116 citations Open access
Semantic Scholar
A New Isolation with Migration Model along Complete Genomes Infers Very Different Divergence Processes among Closely Related Great Ape Species
T. Mailund, Anders E. Halager, M. Westergaard, J. Dutheil +7 more
2012PLoS Genetics112 citations Open access
Semantic Scholar
SIMULATION FROM ENDPOINT-CONDITIONED, CONTINUOUS-TIME MARKOV CHAINS ON A FINITE STATE SPACE, WITH APPLICATIONS TO MOLECULAR EVOLUTION
A. Hobolth, Eric A. Stone
2009Annals of Applied Statistics109 citations Open access
Semantic Scholar
Estimating Divergence Time and Ancestral Effective Population Size of Bornean and Sumatran Orangutan Subspecies Using a Coalescent Hidden Markov Model
T. Mailund, J. Dutheil, A. Hobolth, G. Lunter +1 more
2011PLoS Genetics95 citations Open access
Semantic Scholar
Statistical Inference in the Wright–Fisher Model Using Allele Frequency Data
Paula Tataru, Maria Simonsen, T. Bataillon, A. Hobolth
2016Systematic Biology92 citations Open access
Semantic Scholar
Extensive X-linked adaptive evolution in central chimpanzees
C. Hvilsom, Y. Qian, T. Bataillon, Ying-Rui Li +13 more
2012Proceedings of the National Academy of Sciences of the United States of America90 citations Open access
Semantic Scholar
Comparative analysis of protein coding sequences from human, mouse and the domesticated pig
F. G. Jørgensen, A. Hobolth, H. Hornshøj, C. Bendixen +2 more
2005BMC Biology89 citations Open access
Semantic Scholar
Extreme selective sweeps independently targeted the X chromosomes of the great apes
Kiwoong Nam, K. Munch, A. Hobolth, J. Dutheil +5 more
2015Proceedings of the National Academy of Sciences of the United States of America75 citations Open access
Semantic Scholar
Pan-cancer screen for mutations in non-coding elements with conservation and cancer specificity reveals correlations with expression and survival
H. Hornshøj, M. Nielsen, Nicholas A. Sinnott-Armstrong, Michal P. Switnicki +7 more
2017npj Genomic Medicine61 citations Open access
Semantic Scholar
Quantifying the impact of protein tertiary structure on molecular evolution.
S. Choi, A. Hobolth, Douglas M Robinson, H. Kishino +1 more
2007Molecular biology and evolution57 citations Open access
Semantic Scholar
Statistical Applications in Genetics and Molecular Biology Statistical Inference in Evolutionary Models of DNA Sequences via the EM Algorithm
A. Hobolth, J. L. Jensen
201153 citations
Semantic Scholar
The SMC′ Is a Highly Accurate Approximation to the Ancestral Recombination Graph
Peter R. Wilton, S. Carmi, A. Hobolth
2015Genetics50 citations Open access
Semantic Scholar
Phase-type distributions in population genetics
A. Hobolth, A. Siri-Jégousse, M. Bladt
2018bioRxiv47 citations Open access
Semantic Scholar
Discovery and characterization of coding and non-coding driver mutations in more than 2,500 whole cancer genomes
E. Rheinbay, M. Nielsen, F. Abascal, Grace Tiao +69 more
2017bioRxiv46 citations Open access
Semantic Scholar
A Markov chain Monte Carlo Expectation Maximization Algorithm for Statistical Analysis of DNA Sequence Evolution with Neighbor-Dependent Substitution Rates
A. Hobolth
200844 citations
Semantic Scholar
Importance Sampling for the Infinite Sites Model
A. Hobolth, M. Uyenoyama, Carsten Wiuf
2008Statistical Applications in Genetics and Molecular Biology40 citations Open access
Semantic Scholar
Markovian approximation to the finite loci coalescent with recombination along multiple sequences.
A. Hobolth, J. L. Jensen
2014Theoretical Population Biology39 citations
Semantic Scholar
Non-coding cancer driver candidates identified with a sample- and position-specific model of the somatic mutation rate
Malene Juul, Johanna Bertl, Qian-Yun Guo, M. Nielsen +5 more
2017eLife38 citations Open access
Semantic Scholar
On Computing the Coalescence Time Density in an Isolation-With-Migration Model With Few Samples
A. Hobolth, L. N. Andersen, T. Mailund
2011Genetics38 citations Open access
Semantic Scholar
Inference Under a Wright-Fisher Model Using an Accurate Beta Approximation
Paula Tataru, T. Bataillon, A. Hobolth
2015Genetics36 citations Open access
Semantic Scholar
Inference of Purifying and Positive Selection in Three Subspecies of Chimpanzees (Pan troglodytes) from Exome Sequencing
T. Bataillon, Jinjie Duan, C. Hvilsom, Xin Jin +11 more
2015Genome Biology and Evolution35 citations Open access
Semantic Scholar
Comparison of methods for calculating conditional expectations of sufficient statistics for continuous time Markov chains
Paula Tataru, A. Hobolth
2011BMC Bioinformatics30 citations Open access
Semantic Scholar
Summary Statistics for Endpoint-Conditioned Continuous-Time Markov Chains
A. Hobolth, J. L. Jensen
2011Journal of Applied Probability29 citations Open access
Semantic Scholar
Pseudo-Likelihood Analysis of Codon Substitution Models with Neighbor-Dependent Rates
O. F. Christensen, A. Hobolth, J. L. Jensen
2005J. Comput. Biol.27 citations
Semantic Scholar
An alternative derivation of the stationary distribution of the multivariate neutral Wright-Fisher model for low mutation rates with a view to mutation rate estimation from site frequency data.
D. Schrempf, A. Hobolth
2017Theoretical Population Biology22 citations Open access
Semantic Scholar
Efficient computation in the IM model
L. N. Andersen, T. Mailund, A. Hobolth
2013Journal of Mathematical Biology21 citations
Semantic Scholar
Ancestral population genomics.
J. Dutheil, A. Hobolth
2012Methods in molecular biology20 citations Open access
Semantic Scholar
CpG + CpNpG analysis of protein-coding sequences from tomato.
A. Hobolth, R. Nielsen, Ying Wang, Feinan Wu +1 more
2006Molecular biology and evolution16 citations Open access
Semantic Scholar
A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer data
Johanna Bertl, Qian-Yun Guo, Malene Juul, Søren Besenbacher +4 more
2017BMC Bioinformatics14 citations Open access
Semantic Scholar
The genealogy, site frequency spectrum and ages of two nested mutant alleles.
A. Hobolth, C. Wiuf
2009Theoretical Population Biology14 citations
Semantic Scholar
Applications of Hidden Markov Models for Characterization of Homologous DNA Sequences with a Common Gene
A. Hobolth, J. L. Jensen
2005J. Comput. Biol.14 citations
Semantic Scholar
Studying models of balancing selection using phase-type theory
K. Zeng, B. Charlesworth, A. Hobolth
2020bioRxiv13 citations Open access
Semantic Scholar
The importance of distinguishing between the odds ratio and the incidence rate ratio in GWAS
B. L. Waltoft, C. Pedersen, M. Nyegaard, A. Hobolth
2015BMC Medical Genetics13 citations Open access
Semantic Scholar
Phase-type distributions in mathematical population genetics: An emerging framework.
A. Hobolth, Iker Rivas-González, M. Bladt, Andreas Futschik
2024Theoretical Population Biology12 citations Open access
Semantic Scholar
TRAILS: Tree reconstruction of ancestry using incomplete lineage sorting
Iker Rivas-González, M. Schierup, J. Wakeley, A. Hobolth
2023bioRxiv10 citations Open access
Semantic Scholar
Algorithms for Hidden Markov Models Restricted to Occurrences of Regular Expressions
P. Tataru, Andreas Sand, A. Hobolth, T. Mailund +1 more
2013Biology10 citations Open access
Semantic Scholar
Markov Bridges, Bisection and Variance Reduction
S. Asmussen, A. Hobolth
20129 citations Open access
Semantic Scholar
Bayesian regularization of diffusion tensor images.
J. Frandsen, A. Hobolth, L. Ostergaard, P. Vestergaard-Poulsen +1 more
2006Biostatistics9 citations
Semantic Scholar
Estimating Gene Conversion Tract Length and Rate From PacBio HiFi Data
A. P. Charmouh, Peter Sørud Porsborg, Lasse Thorup Hansen, S. Besenbacher +5 more
2024bioRxiv8 citations Open access
Semantic Scholar
Multivariate phase-type theory for the site frequency spectrum
A. Hobolth, M. Bladt, L. N. Andersen
2021Journal of Mathematical Biology8 citations Open access
Semantic Scholar
Regmex: a statistical tool for exploring motifs in ranked sequence lists from genomics experiments
M. Nielsen, Paula Tataru, Tobias Madsen, A. Hobolth +1 more
2018Algorithms for Molecular Biology8 citations Open access
Semantic Scholar

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