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T. Tan · SciRah

Researcher profile · Semantic Scholar

T. Tan

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T. Tan — researcher profile on SciRah

h-index: 20
Works: 74
Citations: 1,297

Most-cited papers

The Evolution of Triple-Negative Breast Cancer: From Biology to Novel Therapeutics.
C. Anders, V. Abramson, T. Tan, R. Dent
2016American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting99 citations
Semantic Scholar
LBA15 Primary outcome of the phase III SYD985.002/TULIP trial comparing [vic-]trastuzumab duocarmazine to physician’s choice treatment in patients with pre-treated HER2-positive locally advanced or metastatic breast cancer
C. S. Manich, J. O'Shaughnessy, P. Aftimos, E. van den Tweel +13 more
2021Annals of Oncology91 citations Open access
Semantic Scholar
Fatty acid oxidation is a druggable gateway regulating cellular plasticity for driving metastasis in breast cancer
S. Loo, L. Toh, W. Xie, Elina Pathak +29 more
2021Science Advances83 citations Open access
Semantic Scholar
Tissue-specific cell-free DNA degradation quantifies circulating tumor DNA burden
Guan-Hua Zhu, Y. Guo, Danliang Ho, P. Poon +16 more
2021Nature Communications83 citations Open access
Semantic Scholar
First-in-class Microbial Ecosystem Therapeutic 4 (MET4) in combination with immune checkpoint inhibitors in patients with advanced solid tumors (MET4-IO Trial).
A. Spreafico, A. Heirali, D. Araujo, T. Tan +14 more
2023Annals of Oncology78 citations Open access
Semantic Scholar
Multiplex immunohistochemistry/immunofluorescence (mIHC/IF) for PD-L1 testing in triple-negative breast cancer: a translational assay compared with conventional IHC
J. Yeong, T. Tan, Zi-Long Chow, Qing Cheng +15 more
2020Journal of Clinical Pathology64 citations Open access
Semantic Scholar
The impact of Irritable Bowel Syndrome on health-related quality of life: a Singapore perspective
Yu-Tien Wang, Hwee Yong Lim, D. Tai, T. Krishnamoorthy +3 more
2012BMC Gastroenterology58 citations Open access
Semantic Scholar
Novel therapeutic avenues in triple-negative breast cancer: PI3K/AKT inhibition, androgen receptor blockade, and beyond
Jack Junjie Chan, T. Tan, R. Dent
2019Therapeutic Advances in Medical Oncology55 citations Open access
Semantic Scholar
The Evolution of Triple-Negative Breast Cancer: From Biology to Novel Therapeutics.
C. Anders, V. Abramson, T. Tan, R. Dent
2016American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting52 citations
Semantic Scholar
First-in-human phase I/Ib open-label dose-escalation study of GWN323 (anti-GITR) as a single agent and in combination with spartalizumab (anti-PD-1) in patients with advanced solid tumors and lymphomas
S. Piha-Paul, R. Geva, T. Tan, Darren Wt Lim +12 more
2021Journal for ImmunoTherapy of Cancer42 citations Open access
Semantic Scholar
What is the role of immunotherapy in breast cancer?
T. Tan, Jack Junjie Chan, S. Kamis, R. Dent
2018Chinese Clinical Oncology40 citations Open access
Semantic Scholar
Lipoprotein separation in a novel iodixanol density gradient, for composition, density, and phenotype analysis This research was supported by a grant from GlaxoSmithKline. Published, JLR Papers in Press, March 12, 2008.
Michael S. Yee, D. Pavitt, T. Tan, S. Venkatesan +3 more
2008Journal of Lipid Research38 citations Open access
Semantic Scholar
Multi-center evaluation of artificial intelligent imaging and clinical models for predicting neoadjuvant chemotherapy response in breast cancer
Tan-Hong Qi, Ong Hiok Hian, A. Kumaran, T. Tan +20 more
2021Breast Cancer Research and Treatment33 citations Open access
Semantic Scholar
Impact of Cryotherapy on Sensory, Motor, and Autonomic Neuropathy in Breast Cancer Patients Receiving Paclitaxel: A Randomized, Controlled Trial
D. Ng, Chia-Jie Tan, B. Soh, M. Tan +17 more
2020Frontiers in Neurology32 citations Open access
Semantic Scholar
Molecular characterisation and clinical outcomes in RET rearranged non-small cell lung cancer (NSCLC).
A. Tan, A. Seet, G. Lai, T. Lim +17 more
2020Journal of Thoracic Oncology31 citations Open access
Semantic Scholar
Association of mitochondrial DNA content in peripheral blood with cancer-related fatigue and chemotherapy-related cognitive impairment in early-stage breast cancer patients: a prospective cohort study
J. Chae, Peh Siang Chua, T. Ng, A. Yeo +16 more
2018Breast Cancer Research and Treatment28 citations
Semantic Scholar
Complementary Sequential Circulating Tumor Cell (CTC) and Cell-Free Tumor DNA (ctDNA) Profiling Reveals Metastatic Heterogeneity and Genomic Changes in Lung Cancer and Breast Cancer
Say-Li Kong, Xing-Liang Liu, Swee Jin Tan, Joyce A. Tai +19 more
2021Frontiers in Oncology27 citations Open access
Semantic Scholar
Replication and Meta-analysis of the Association between BDNF Val66Met Polymorphism and Cognitive Impairment in Patients Receiving Chemotherapy
Chia-Jie Tan, Sheree Wan Ting Lim, Y. L. Toh, T. Ng +20 more
2018Molecular Neurobiology26 citations Open access
Semantic Scholar
Comprehensive Geriatric Assessment (CGA) based risk factors for increased caregiver burden among elderly Asian patients with cancer.
T. Rajasekaran, T. Tan, W. Ong, K. Koo +5 more
2016Journal of Geriatric Oncology24 citations
Semantic Scholar
A phase I study of an adenoviral vector delivering a MUC1/CD40-ligand fusion protein in patients with advanced adenocarcinoma
T. Tan, W. X. Gladys Ang, W. Wang, H. Chong +22 more
2022Nature Communications20 citations Open access
Semantic Scholar
Clinical best practices in optimal monitoring, early diagnosis, and effective management of antibody–drug conjugate-induced interstitial lung disease or pneumonitis: a multidisciplinary team approach in Singapore
W. Yong, Felicia S. W. Teo, Lynette L. S. Teo, M. Ng +7 more
2022Expert Opinion on Drug Metabolism & Toxicology20 citations Open access
Semantic Scholar
Abstract LB041: THOR-707 (SAR444245), a novel not-alpha IL-2 as monotherapy and in combination with pembrolizumab in advanced/metastatic solid tumors: Interim results from HAMMER, an open-label, multicenter phase 1/2 Study
F. Janku, R. Abdul-Karim, A. Azad, J. Bendell +11 more
2021Clinical research20 citations
Semantic Scholar
Effects of housing value and medical subsidy on treatment and outcomes of breast cancer patients in Singapore: A retrospective cohort study
F. Wong, R. Wong, Siqin Zhou, W. Ong +13 more
2020The Lancet Regional Health - Western Pacific20 citations Open access
Semantic Scholar
Surgery for early breast cancer in the extremely elderly leads to improved outcomes - An Asian population study.
Chee-Meng Lee, Huili Zheng, V. Tan, T. Tan +7 more
2017Breast17 citations
Semantic Scholar
386MO Trastuzumab duocarmazine versus physician's choice therapy in pre-treated HER2-positive metastatic breast cancer: Final results of the phase III TULIP trial
P. Aftimos, N. Turner, J. O'Shaughnessy, E. van den Tweel +15 more
2023Annals of Oncology16 citations
Semantic Scholar
A systematic review and meta-analysis of individual patient data on the impact of the BIM deletion polymorphism on treatment outcomes in epidermal growth factor receptor mutant lung cancer
S. Soh, F. Siddiqui, J. Allen, G. Kim +25 more
2017OncoTarget16 citations Open access
Semantic Scholar
481 Phase 1/2 study of THOR-707 (SAR444245), a pegylated recombinant non-alpha IL-2, as monotherapy and in combination with pembrolizumab or cetuximab in patients (pts) with advanced solid tumors
G. Falchook, H. Gan, S. Fu, M. McKean +14 more
2021Journal for ImmunoTherapy of Cancer15 citations Open access
Semantic Scholar
Identification of Comprehensive Geriatric Assessment Based Risk Factors for Malnutrition in Elderly Asian Cancer Patients
T. Tan, W. Ong, T. Rajasekaran, Khai Nee Koo +5 more
2016PLoS ONE15 citations Open access
Semantic Scholar
COVID-19: impact on and recommendations for breast cancer care: the Singapore experience.
Jack Junjie Chan, Y. Sim, S. Ow, J. Lim +6 more
2020Endocrine-Related Cancer13 citations Open access
Semantic Scholar
Dora: A randomized phase II multicenter maintenance study of olaparib alone or olaparib in combination with durvalumab in platinum responsive advanced triple-negative breast cancer (aTNBC).
Sarah Sammons, T. Tan, T. Traina, Sung-Bae Kim +4 more
2019Journal of Clinical Oncology13 citations
Semantic Scholar
Triple-Negative Breast Cancer: Clinical Features
T. Tan, R. Dent
201813 citations
Semantic Scholar
Survival in triple-negative breast cancer (TNBC): Evidence from the SEER database 2010-2011.
R. Dent, P. Mainwaring, T. Tan, S. Barbier +3 more
201513 citations
Semantic Scholar
Novel Targeted Agents and Immunotherapy in Breast Cancer.
I. Mayer, R. Dent, T. Tan, P. Savas +1 more
2017American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting12 citations
Semantic Scholar
Individualized Molecular Profiling for Allocation to Clinical Trials Singapore Study—An Asian Tertiary Cancer Center Experience
A. Seet, A. Tan, T. Tan, M. Ng +24 more
2021JCO Precision Oncology10 citations Open access
Semantic Scholar
First-in-class microbial ecosystem therapeutics 4 (MET4) in metastatic solid cancer patients treated with immunotherapy: MET4-IO.
D. Araujo, Marc Oliva Bernal, T. Tan, A. Heirali +15 more
20209 citations
Semantic Scholar
Are There Any Clinically Relevant Subgroups of Triple-Negative Breast Cancer in 2018?
Jack Junjie Chan, T. Tan, R. Dent
2018Journal of Oncology Practice9 citations
Semantic Scholar
A phase 1 study of the safety, pharmacokinetics and pharmacodynamics of escalating doses followed by dose expansion of the selective inhibitor of nuclear export (SINE) selinexor in Asian patients with advanced or metastatic malignancies
J. Ho, V. Heong, W. Yong, R. Soo +23 more
2022Therapeutic Advances in Medical Oncology8 citations Open access
Semantic Scholar
Integrating immunotherapy in the (neo)adjuvant setting of early breast cancer
Jack Junjie Chan, T. Tan, R. Dent
2020Current Opinion in Oncology7 citations
Semantic Scholar
Early Triple-Negative Breast Cancers in a Singapore Cohort Exhibit High PIK3CA Mutation Rates Associated With Low PD-L1 Expression.
J. Yeong, Denise Goh, T. Tan, Benedict Tan +13 more
2023Modern Pathology6 citations Open access
Semantic Scholar
Candida Endophthalmitis Treated Successfully With Isavuconazole: A Case Report
E. C. Y. Sng, A. Tan, P. Zhou, T. Tan +3 more
2021Open Forum Infectious Diseases6 citations Open access
Semantic Scholar
First-in-man study of Ad-sig-hMUC1/ecdCD40L vaccine for immunotherapy of MUC1 overexpressing epithelial cancers.
T. Tan, J. Chia, H. Chong, Xinhua Li +4 more
20185 citations
Semantic Scholar
Referrals to a Phase I Clinic and Trial Enrollment in the Molecular Screening Era.
T. Tan, M. Rheaume, Lisa Wang, Helen Chow +5 more
2019The Oncologist3 citations Open access
Semantic Scholar
Feasibility study of microbial ecosystem therapeutics (MET-4) to evaluate effects of fecal microbiome in patients on immunotherapy (MET4-IO).
T. Tan, M. Butler, A. Hansen, D. Hogg +10 more
2019Journal of Clinical Oncology3 citations
Semantic Scholar
Abstract PD11-12: PD11-12 DORA: A Phase II, Multicenter, International, Non-Comparator Study of Olaparib (O) +/- Durvalumab (D) as a chemotherapy-free maintenance strategy in Platinum tReated Advanced Triple-Negative Breast Cancer (aTNBC)
S. Sammons, T. Tan, Young Hyunk Im, T. Traina +4 more
2023Cancer Research2 citations
Semantic Scholar
Association between Breast Cancer Polygenic Risk Score and Chemotherapy-Induced Febrile Neutropenia: Null Results
S. S. Ong, P. Ho, A. Khng, E. Lim +24 more
2022Cancers2 citations Open access
Semantic Scholar
Exquisitely Platinum-Sensitive Triple-Negative Breast Cancer, Time for BRCA Methylation Testing?
T. Tan, J. Fink, T. Tay, Binny Jaradi +6 more
2022JCO Precision Oncology2 citations
Semantic Scholar
CONTESSA TRIO: A multinational, multicenter, phase (P) II study of tesetaxel (T) plus three different PD-(L)1 inhibitors in patients (Pts) with metastatic triple-negative breast cancer (TNBC) and tesetaxel monotherapy in elderly pts with HER2-metastatic breast cancer (MBC).
S. Tolaney, I. Bondarenko, A. Chan, N. Dacosta +16 more
20202 citations
Semantic Scholar
Hyperprogressive disease in advanced triple-negative breast cancer (aTNBC) treated with immunotherapy (IO).
T. Tan, D. Cescon, Lisa Wang, E. Amir +10 more
2019Journal of Clinical Oncology2 citations
Semantic Scholar
Oregovomab (orego) and nivolumab (nivo) as a combinatorial immunotherapy strategy for recurrent epithelial ovarian cancer (rEOC): ORION-01 phase Ib cohort.
Jack Junjie Chan, S. Tan, T. Lim, T. Tan +5 more
2018Annals of Oncology2 citations Open access
Semantic Scholar
Abstract OT3-04-02: The DORA trial: A non-comparator randomised phase II multi-center maintenance study of olaparib alone or olaparib in combination with durvalumab in platinum treated advanced triple negative breast cancer (TNBC)
R. Dent, T. Tan, S.-B. Kim, T. Traina +4 more
20182 citations
Semantic Scholar

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