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B. Klink · SciRah

Researcher profile · Semantic Scholar

B. Klink

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B. Klink — researcher profile on SciRah

h-index: 37
Works: 137
Citations: 5,279

Most-cited papers

Human gastric cancer modelling using organoids
T. Seidlitz, Sebastian R Merker, A. Rothe, F. Zakrzewski +16 more
2018Gut307 citations Open access
Semantic Scholar
Integrative genomic and transcriptomic analysis of leiomyosarcoma
Priya Chudasama, S. Mughal, M. Sanders, D. Hübschmann +37 more
2018Nature Communications268 citations Open access
Semantic Scholar
Comprehensive Genomic and Transcriptomic Analysis for Guiding Therapeutic Decisions in Patients with Rare Cancers.
P. Horák, C. Heining, S. Kreutzfeldt, B. Hutter +55 more
2021Cancer Discovery241 citations Open access
Semantic Scholar
NRG1 Fusions in KRAS Wild-Type Pancreatic Cancer.
C. Heining, P. Horák, S. Uhrig, Paula L Codo +35 more
2018Cancer Discovery203 citations
Semantic Scholar
The biology and mathematical modelling of glioma invasion: a review
J. L. Alfonso, Katrin Talkenberger, Michael Seifert, B. Klink +4 more
2017Journal of the Royal Society Interface202 citations Open access
Semantic Scholar
Characteristics of Pediatric vs Adult Pheochromocytomas and Paragangliomas
C. Pamporaki, B. Hamplová, M. Peitzsch, A. Prejbisz +13 more
2017Journal of Clinical Endocrinology and Metabolism160 citations Open access
Semantic Scholar
Precision oncology based on omics data: The NCT Heidelberg experience
P. Horák, B. Klink, C. Heining, S. Gröschel +27 more
2017International Journal of Cancer155 citations Open access
Semantic Scholar
Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology
A. Gołȩbiewska, A. Hau, A. Oudin, D. Stieber +37 more
2020Acta Neuropathologica137 citations Open access
Semantic Scholar
The landscape of chromothripsis across adult cancer types
N. Voronina, John K. L. Wong, D. Hübschmann, M. Hlevnjak +26 more
2020Nature Communications125 citations Open access
Semantic Scholar
Comprehensive molecular characterization of multifocal glioblastoma proves its monoclonal origin and reveals novel insights into clonal evolution and heterogeneity of glioblastomas
K. Abou-El-Ardat, Michael Seifert, K. Becker, Sophie Eisenreich +10 more
2017Neuro-Oncology107 citations Open access
Semantic Scholar
Isogenic FUS-eGFP iPSC Reporter Lines Enable Quantification of FUS Stress Granule Pathology that Is Rescued by Drugs Inducing Autophagy
Lara Marrone, I. Poser, Ian Casci, Julia Japtok +17 more
2018Stem Cell Reports96 citations Open access
Semantic Scholar
Mutations in EXOSC2 are associated with a novel syndrome characterised by retinitis pigmentosa, progressive hearing loss, premature ageing, short stature, mild intellectual disability and distinctive gestalt
N. Di Donato, T. Neuhann, Anne-Karin Kahlert, B. Klink +17 more
2016Journal of Medical Genetics91 citations Open access
Semantic Scholar
Defective homologous recombination DNA repair as therapeutic target in advanced chordoma
S. Gröschel, D. Hübschmann, Francesco Raimondi, P. Horák +35 more
2019Nature Communications79 citations Open access
Semantic Scholar
Metabolome-guided genomics to identify mutations in isocitrate dehydrogenase, fumarate hydratase and succinate dehydrogenase genes in pheochromocytoma and paraganglioma
S. Richter, L. Gieldon, Ying Pang, M. Peitzsch +19 more
2018Genetics in Medicine78 citations Open access
Semantic Scholar
Metabologenomics of Phaeochromocytoma and Paraganglioma: An Integrated Approach for Personalised Biochemical and Genetic Testing.
G. Eisenhofer, B. Klink, S. Richter, J. Lenders +1 more
2017Clinical biochemist reviews76 citations
Semantic Scholar
Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis
J. Guyon, I. Fernández-Moncada, C. Larrieu, C. Bouchez +28 more
2022EMBO Molecular Medicine73 citations Open access
Semantic Scholar
The CD98 Heavy Chain Is a Marker and Regulator of Head and Neck Squamous Cell Carcinoma Radiosensitivity
D. Digomann, I. Kurth, A. Tyutyunnykova, O. Chen +21 more
2019Clinical Cancer Research69 citations
Semantic Scholar
An Epigenetic Reprogramming Strategy to Resensitize Radioresistant Prostate Cancer Cells.
C. Peitzsch, Monica Cojoc, L. Hein, I. Kurth +16 more
2016Cancer Research66 citations Open access
Semantic Scholar
Comprehensive cancer predisposition testing within the prospective MASTER trial identifies hereditary cancer patients and supports treatment decisions for rare cancers.
A. Jahn, A. Rump, T. Widmann, C. Heining +73 more
2022Annals of Oncology64 citations Open access
Semantic Scholar
Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia
Sharissa L. Latham, Nadja Ehmke, P. Reinke, M. H. Taft +23 more
2018Nature Communications62 citations Open access
Semantic Scholar
Patient-Derived Organoids of Cholangiocarcinoma
C. Maier, Lei Zhu, Lahiri Kanth Nanduri, Daniel Kühn +10 more
2021International Journal of Molecular Sciences58 citations Open access
Semantic Scholar
Epigenetic Mutation of the Succinate Dehydrogenase C Promoter in a Patient With Two Paragangliomas.
S. Richter, B. Klink, Brit Nacke, A. D. de Cubas +8 more
2016Journal of Clinical Endocrinology and Metabolism55 citations
Semantic Scholar
Diagnostic value of partial exome sequencing in developmental disorders
L. Gieldon, Luisa Mackenroth, Anne-Karin Kahlert, J. Lemke +16 more
2018PLoS ONE51 citations Open access
Semantic Scholar
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification
Celina Tretter, N. de Andrade Krätzig, M. Pecoraro, S. Lange +35 more
2023Nature Communications42 citations Open access
Semantic Scholar
Cell adhesion heterogeneity reinforces tumour cell dissemination: novel insights from a mathematical model
D. Reher, B. Klink, A. Deutsch, Anja Voss-Böhme
2017Biology Direct42 citations Open access
Semantic Scholar
Chromosomal instability induced by increased BIRC5/Survivin levels affects tumorigenicity of glioma cells
Marina Conde, Susanne Michen, Ralf Wiedemuth, B. Klink +3 more
2017BMC Cancer41 citations Open access
Semantic Scholar
The contribution of homology arms to nuclease-assisted genome engineering
O. Baker, S. Tsurkan, Jun Fu, B. Klink +6 more
2017Nucleic Acids Research40 citations Open access
Semantic Scholar
Response to olaparib in a PALB2 germline mutated prostate cancer and genetic events associated with resistance
P. Horák, J. Weischenfeldt, G. von Amsberg, B. Beyer +20 more
2019Cold Spring Harbor molecular case studies37 citations Open access
Semantic Scholar
Network-based analysis of prostate cancer cell lines reveals novel marker gene candidates associated with radioresistance and patient relapse
Michael Seifert, C. Peitzsch, I. Gorodetska, Caroline Börner +2 more
2019PLoS Comput. Biol.36 citations Open access
Semantic Scholar
Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas
Paal W Wallace, Catleen Conrad, S. Brückmann, Ying Pang +22 more
2020Journal of Pathology35 citations Open access
Semantic Scholar
Author Correction: Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia
Sharissa L. Latham, Nadja Ehmke, P. Reinke, M. H. Taft +23 more
2018Nature Communications35 citations Open access
Semantic Scholar
Synergistic Highly Potent Targeted Drug Combinations in different Pheochromocytoma Models including Human Tumor Cultures.
M. Fankhauser, N. Bechmann, M. Lauseker, Judith Goncalves +22 more
2019Endocrinology34 citations Open access
Semantic Scholar
Network-based analysis of oligodendrogliomas predicts novel cancer gene candidates within the region of the 1p/19q co-deletion
Josef Gladitz, B. Klink, Michael Seifert
2018Acta Neuropathologica Communications34 citations Open access
Semantic Scholar
Optimizing Genetic Workup in Pheochromocytoma and Paraganglioma by Integrating Diagnostic and Research Approaches
L. Gieldon, D. William, K. Hackmann, Winnie Jahn +19 more
2019Cancers33 citations Open access
Semantic Scholar
Mutant IDH1 Differently Affects Redox State and Metabolism in Glial Cells of Normal and Tumor Origin
Julia Biedermann, Matthias Preussler, Marina Conde, M. Peitzsch +16 more
2019Cancers33 citations Open access
Semantic Scholar
AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion
A. Schuster, E. Klein, V. Neirinckx, A. Knudsen +15 more
2020Nature Communications32 citations Open access
Semantic Scholar
Targeted capture-based NGS is superior to multiplex PCR-based NGS for hereditary BRCA1 and BRCA2 gene analysis in FFPE tumor samples
F. Zakrzewski, L. Gieldon, A. Rump, Michael Seifert +13 more
2019BMC Cancer29 citations Open access
Semantic Scholar
A mathematical model of the metastatic bottleneck predicts patient outcome and response to cancer treatment
Ewa Szczurek, T. Krüger, B. Klink, N. Beerenwinkel
2020PLoS Comput. Biol.27 citations Open access
Semantic Scholar
Nivolumab maintenance after salvage autologous stem cell transplantation results in long‐term remission in multiple relapsed primary CNS lymphoma
D. Terziev, B. Hutter, B. Klink, A. Stenzinger +9 more
2018European Journal of Haematology26 citations
Semantic Scholar
Next-generation panel sequencing identifies NF1 germline mutations in three patients with pheochromocytoma but no clinical diagnosis of neurofibromatosis type 1.
L. Gieldon, J. Masjkur, S. Richter, R. Därr +12 more
2018European Journal of Endocrinology24 citations Open access
Semantic Scholar
Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease
Lara Marrone, C. Bus, David C. Schöndorf, J. Fitzgerald +12 more
2018PLoS ONE23 citations Open access
Semantic Scholar
Personalized drug testing in human pheochromocytoma/paraganglioma primary cultures.
Katharina Wang, Ina Schütze, S. Gulde, N. Bechmann +34 more
2022Endocrine-Related Cancer22 citations Open access
Semantic Scholar
Comparative analysis of histologically classified oligodendrogliomas reveals characteristic molecular differences between subgroups
C. Lauber, B. Klink, Michael Seifert
2018BMC Cancer21 citations Open access
Semantic Scholar
Whole exome sequencing identifies mTOR and KEAP1 as potential targets for radiosensitization of HNSCC cells refractory to EGFR and β1 integrin inhibition
E. Klapproth, Ellen Dickreuter, F. Zakrzewski, Michael Seifert +5 more
2018OncoTarget20 citations Open access
Semantic Scholar
Pericytes/vessel-associated mural cells (VAMCs) are the major source of key epithelial-mesenchymal transition (EMT) factors SLUG and TWIST in human glioma
Lisa Mäder, A. Blank, D. Capper, Janina Jansong +11 more
2018OncoTarget19 citations Open access
Semantic Scholar
Ready to clone: CNV detection and breakpoint fine-mapping in breast and ovarian cancer susceptibility genes by high-resolution array CGH
K. Hackmann, Franziska Kuhlee, Elitza Betcheva-Krajcir, Anne-Karin Kahlert +8 more
2016Breast Cancer Research and Treatment17 citations
Semantic Scholar
CASP9 germline mutation in a family with multiple brain tumors
M. Ronellenfitsch, Jieun Oh, K. Satomi, K. Sumi +12 more
2018Brain Pathology15 citations Open access
Semantic Scholar
Patterns of Tumor Progression Predict Small and Tissue-Specific Tumor-Originating Niches
T. Buder, A. Deutsch, B. Klink, Anja Voss-Böhme
2018bioRxiv15 citations Open access
Semantic Scholar
XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase
A. Sharma, H. Erasimus, Lia M. Pinto, Marie-christine Caron +13 more
2021Nucleic Acids Research14 citations Open access
Semantic Scholar
Different Effects of RNAi-Mediated Downregulation or Chemical Inhibition of NAMPT in an Isogenic IDH Mutant and Wild-Type Glioma Cell Model
Maximilian Clausing, D. William, Matthias Preussler, Julia Biedermann +6 more
2022International Journal of Molecular Sciences13 citations Open access
Semantic Scholar

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E. Schröck×16
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A. Rump×11
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L. Gieldon×11
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