Jin-Chang Lu

Most-cited papers

1. IRX1 hypomethylation promotes osteosarcoma metastasis via induction of CXCL14/NF-κB signaling.

   Jin-Chang Lu, G. Song, Qing-Lian Tang, Chang-Ye Zou +11 more

   2015Journal of Clinical Investigation117 citations Open access

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2. Downregulation of MCT1 inhibits tumor growth, metastasis and enhances chemotherapeutic efficacy in osteosarcoma through regulation of the NF-κB pathway.

   Zhi-Qiang Zhao, Man-si Wu, Chang-Ye Zou, Qing-Lian Tang +8 more

   2014Cancer Letters115 citations

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3. MiR-26a inhibits stem cell-like phenotype and tumor growth of osteosarcoma by targeting Jagged1

   Jin-Chang Lu, G. Song, Qing-Lian Tang, J. Yin +10 more

   2017Oncogene90 citations

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4. Cross-species genomics identifies DLG2 as a tumor suppressor in osteosarcoma

   Y. Shao, G. Wood, Jin-Chang Lu, Qing-Lian Tang +8 more

   2018Oncogene79 citations Open access

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5. Reprograming the tumor immunologic microenvironment using neoadjuvant chemotherapy in osteosarcoma

   C. Deng, Yanyang Xu, Jianchang Fu, Xiao-Jun Zhu +10 more

   2020Cancer Science76 citations Open access

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6. A nanodrug combining CD47 and sonodynamic therapy efficiently inhibits osteosarcoma deterioration.

   Ming Gong, Yufeng Huang, Huixiong Feng, Jia-Ming Lin +7 more

   2023Journal of Controlled Release67 citations

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7. Degalactotigonin, a Natural Compound from Solanum nigrum L., Inhibits Growth and Metastasis of Osteosarcoma through GSK3β Inactivation–Mediated Repression of the Hedgehog/Gli1 Pathway

   Zhi-Qiang Zhao, Q. Jia, Man-si Wu, Xian-Biao Xie +11 more

   2017Clinical Cancer Research62 citations Open access

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8. Energy stress-induced lncRNA HAND2-AS1 represses HIF1α-mediated energy metabolism and inhibits osteosarcoma progression.

   Yao Kang, Xiao-Jun Zhu, Yanyang Xu, Qing-Lian Tang +7 more

   2018American Journal of Cancer Research55 citations

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9. Dihydromyricetin Activates AMP-Activated Protein Kinase and P38MAPK Exerting Antitumor Potential in Osteosarcoma

   Zhi-Qiang Zhao, Junqiang Yin, Man-si Wu, G. Song +10 more

   2014Cancer Prevention Research53 citations

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10. Genetic and clonal dissection of osteosarcoma progression and lung metastasis

    Huai-Yuan Xu, Xiao-Jun Zhu, H. Bao, Tony Wh Shek +22 more

    2018International Journal of Cancer49 citations

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11. Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs.

    Chuang-Zhong Deng, Yanyang Xu, Hongmin Chen, Xiao-Jun Zhu +9 more

    2024Cell Reports41 citations Open access

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12. Immune Landscape of the Tumor Microenvironment Identifies Prognostic Gene Signature CD4/CD68/CSF1R in Osteosarcoma

    YiJiang Song, Yanyang Xu, Xiao-Jun Zhu, Jianchang Fu +7 more

    2020Frontiers in Oncology40 citations Open access

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13. Osteosarcoma cells secrete CXCL14 that activates integrin α11β1 on fibroblasts to form a lung metastatic niche.

    Yanyang Xu, Chuang-Zhong Deng, Hongmin Chen, YiJiang Song +19 more

    2024Cancer Research37 citations Open access

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14. A Comparative Study Between Minimally Invasive Spine Surgery and Traditional Open Surgery for Patients with Spinal Metastasis.

    Xiao-Jun Zhu, Jin-Chang Lu, Huai-Yuan Xu, Qing-Lian Tang +6 more

    2020Spine35 citations

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15. CDH4 is a novel determinant of osteosarcoma tumorigenesis and metastasis

    Qing-Lian Tang, Jin-Chang Lu, Chang-Ye Zou, Y. Shao +7 more

    2018Oncogene31 citations

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16. Gene Expression Classifier Reveals Prognostic Osteosarcoma Microenvironment Molecular Subtypes

    YiJiang Song, Yanyang Xu, C. Deng, Xiao-Jun Zhu +7 more

    2021Frontiers in Immunology26 citations Open access

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17. Nickel–titanium alloy porous scaffolds based on a dominant cellular structure manufactured by laser powder bed fusion have satisfactory osteogenic efficacy

    Jia-Ming Lin, A. Yan, Anfei Huang, Qing-Lian Tang +9 more

    2024Materials Today Bio18 citations

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18. Surgical outcomes and risk factors for surgical complications after en bloc resection following reconstruction with 3D-printed artificial vertebral body for thoracolumbar tumors

    Jin-Xin Hu, G. Song, Hongmin Chen, Huai-Yuan Xu +7 more

    2023World Journal of Surgical Oncology17 citations Open access

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19. Comprehensive analysis of immune infiltration and gene expression for predicting survival in patients with sarcomas

    Hong-Min Chen, YiJiang Song, C. Deng, Yanyang Xu +6 more

    2020Aging15 citations Open access

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20. Targeting OxLDL-mediated CD36 + CAF reprogramming potentiates PD-1 immunotherapy in osteosarcoma

    Anyu Zeng, Hongmin Chen, Tianqi Luo, Weiqing Chen +12 more

    2025Molecular Cancer14 citations Open access

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21. Innovative sarcoma therapy using multifaceted nano-PROTAC-induced EZH2 degradation and immunity enhancement.

    Zhihao Chen, Yi Tai, Chuang-Zhong Deng, Ya-Meng Sun +11 more

    2025Biomaterials14 citations

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22. 3D-printed modular prostheses for reconstruction of intercalary bone defects after joint-sparing limb salvage surgery for femoral diaphyseal tumours

    Xiao-Jun Zhu, Jin-Xin Hu, Jia-Ming Lin, G. Song +4 more

    2024Bone & Joint Open11 citations Open access

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23. Minimally invasive separation surgery for the treatment of spinal metastases with small incision and freehand pedicle screw fixation: the surgical learning curve

    Jia-Ming Lin, Xiao-Jun Zhu, Qing-Lian Tang, Jin-Chang Lu +9 more

    2022BMC Musculoskeletal Disorders11 citations Open access

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24. IRX1 hypomethylation in osteosarcoma metastasis

    Jin-Chang Lu, Jin Wang

    2015OncoTarget8 citations Open access

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25. Camrelizumab in combination with doxorubicin, cisplatin, ifosfamide, and methotrexate in neoadjuvant treatment of resectable osteosarcoma: A prospective, single‐arm, exploratory phase II trial

    Qing-Lian Tang, Xin-Ke Zhang, Xiao-Jun Zhu, Huai-Yuan Xu +7 more

    2024Cancer Medicine7 citations Open access

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26. [Role of SCUBE3 in promoting osteosarcoma cell growth and its association with prognosis].

    G. Song, Jin Wang, Jin-Chang Lu, Huai-Yuan Xu +6 more

    2014Nan fang yi ke da xue xue bao = Journal of Southern Medical University7 citations

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27. The efficacy and safety of short-course neoadjuvant denosumab for en bloc spondylectomy in spinal giant cell tumor of bone: a preliminary report

    Qing-Lian Tang, Jin-Chang Lu, Xiao-Jun Zhu, G. Song +4 more

    2023European spine journal6 citations Open access

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28. Lenvatinib Monotherapy Versus Lenvatinib in Combination with PD-1 Blockades as Re-Challenging Treatment for Patients with Metastatic Osteosarcoma: A Real-World Study

    G. Song, Qing-Lian Tang, Jin-Chang Lu, Huai-Yuan Xu +6 more

    2025Drug Design, Development and Therapy5 citations Open access

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29. [Expression of chemokine CXCL14 in primary osteosarcoma and its association with prognosis].

    Jin-Chang Lu, Jin Wang, Bi-Cheng Yong, G. Song +6 more

    2013Nan fang yi ke da xue xue bao = Journal of Southern Medical University3 citations

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30. Design and validation of a novel 3D-printed glenohumeral fusion prosthesis for the reconstruction of proximal humerus bone defects: a biomechanical study

    Jia-Ming Lin, G. Song, Anfei Huang, Jin-Xin Hu +6 more

    2024Frontiers in Bioengineering and Biotechnology2 citations Open access

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31. Sagittal en bloc resection of thoracolumbar tumours: a report of thirty one cases

    Xiao-Jun Zhu, Jin-Xin Hu, Wenquan Xu, G. Song +7 more

    2024International Orthopaedics2 citations

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32. Retrospective analysis of the clinical outcomes of paraspinal soft-tissue sarcoma.

    Qing-Lian Tang, Anqi Wang, G. Song, Huai-Yuan Xu +4 more

    2024The spine journal2 citations

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33. Retinoic Acid Metabolism-Related Enzyme Signature Identified Prognostic and Immune Characteristics in Sarcoma

    Huai-Yuan Xu, Jin-Xin Hu, YiJiang Song, Hong-Min Chen +9 more

    2022Frontiers in Cell and Developmental Biology2 citations Open access

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34. Limb salvage for malignant bone tumors of distal tibia with 3D-printed ankle joint arthrodesis prosthesis and preserving subtalar joint

    Xiao-Jun Zhu, Jin-Xin Hu, Anqi Wang, G. Song +4 more

    2026Holistic Integrative Oncology1 citations Open access

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35. The histone lysine methyltransferase NSD3 drives osteosarcomagenesis by inactivating ARID3A.

    Jin-Chang Lu, Y. Shao, Sanjay Saw, Hui Fang +8 more

    2025Cancer Letters1 citations

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36. Development and validation of a novel immune-related prognostic model and the potential metastatic mechanism in synovial sarcoma

    Yufeng Huang, Ming Gong, Jia-Ming Lin, Qing-Lian Tang +10 more

    2024Frontiers in Immunology1 citations Open access

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37. Mass spectrometry-based proteomics identifies Serpin B9 as a key protein in promoting bone metastases in lung cancer.

    Yufeng Huang, Ming Gong, Hongmin Chen, Chuang-Zhong Deng +12 more

    2024Molecular Cancer Research1 citations

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38. Corrigendum to "Downregulation of MCT1 inhibits tumor growth, metastasis and enhances chemotherapeutic efficacy in osteosarcoma through regulation of the NF-κB pathway" [Canc. Lett. 342 (2014) 150-158].

    Zhi-Qiang Zhao, Man-si Wu, Chang-Ye Zou, Qing-Lian Tang +8 more

    2021Cancer Letters1 citations

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39. The genomic and evolutionary landscape of osteosarcoma progression and lung metastasis.

    Jin Wang, H. Bao, Huai-Yuan Xu, T. Shek +16 more

    20171 citations

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40. Clinical Outcomes of a Customized 3D-printed Arthrodesis Prosthesis for Reconstruction of Segmental Defects following Tumor Resection in the Proximal Humerus.

    Xiao J. Zhu, Jia M. Lin, G. Song, Jin-Chang Lu +4 more

    2026Journal of shoulder and elbow surgery0 citations

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41. Lenvatinib in Combination with PD-1 Blockades as Re-Challenging Treatment for Patients with Metastatic Soft Tissue Sarcoma Following TKI Treatment Failure: A Retrospective Study

    Guo-Quan Song, Jin-Xin Hu, Wenqian He, Chuang-Zhong Deng +8 more

    2026Drug Design, Development and Therapy0 citations Open access

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42. Phase III Trial of Pegylated Liposomal Doxorubicin for Patients with Advanced and Refractory Desmoid Tumors

    Huai-Yuan Xu, Jin-Xin Hu, Yun Zhang, Ai-Hua Zhuang +14 more

    2026Clinical Cancer Research0 citations Open access

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43. Surgical technique and outcomes for tumors simultaneously involving the thoracic vertebrae and posterior chest wall

    Anqi Wang, Xiao-Jun Zhu, Jin-Xin Hu, Qing-Lian Tang +2 more

    2026BMC Cancer0 citations Open access

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44. Phase Ib/II study of fluzoparib in combination with dalpiciclib in patients with locally advanced or metastatic sarcoma.

    Anqi Wang, Jin-Chang Lu, Tianqi Luo, Jin Wang

    2025Journal of Clinical Oncology0 citations

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45. Comparative study of eGFR in cancer and non-cancer individuals: a multicenter analysis

    Bao-Kui Ye, Xin Luo, Yunhan Luo, Zhao-Hui Zhou +29 more

    2025Frontiers in Medicine0 citations

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46. Camrelizumab in combination with doxorubicin, cisplatin, ifosfamide, and methotrexate as neoadjuvant therapy for osteosarcoma: A single-arm, exploratory phase II trial.

    Qing-Lian Tang, Xiao-Jun Zhu, G. Song, Jin-Chang Lu +6 more

    2023Journal of Clinical Oncology0 citations

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47. Development and Validation of a Novel Immune-Related Prognostic Model and the Potential Mechanism in Metastatic Synovial Sarcoma

    Yufeng Huang, Ming Gong, Qing-Lian Tang, Hong-Min Chen +11 more

    2021Social Science Research Network0 citations Open access

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48. Retinoic acid metabolism-related enzyme signature identified prognostic and immunotherapeutic efficiency in sarcoma

    Huai-Yuan Xu, Jin-Xin Hu, YiJiang Song, Hongmin Chen +9 more

    20210 citations Open access

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49. [Effectiveness evaluation of prosthetic revision for aseptic loosening in oncology prosthesis].

    Jin Wang, Jing-Nan Shen, Junqiang Yin, Gang Huang +4 more

    2011Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery0 citations

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