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D. Gaglio · SciRah

Researcher profile · Semantic Scholar

D. Gaglio

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D. Gaglio — researcher profile on SciRah

h-index: 23
Works: 47
Citations: 2,039

Most-cited papers

Molecular Systems Biology Peer Review Process File Oncogenic K-ras Decouples Glucose and Glutamine Metabolism to Support Cancer Cell Growth Transaction Report
D. Gaglio, C. Metallo, P. Gameiro, Karsten Hiller +6 more
440 citations
Semantic Scholar
Glutamine Deprivation Induces Abortive S-Phase Rescued by Deoxyribonucleotides in K-Ras Transformed Fibroblasts
D. Gaglio, C. Soldati, M. Vanoni, L. Alberghina +1 more
2009PLoS ONE156 citations Open access
Semantic Scholar
A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth: The WarburQ effect
Chiara Damiani, R. Colombo, D. Gaglio, F. Mastroianni +5 more
2017PLoS Comput. Biol.108 citations Open access
Semantic Scholar
Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth
D. Gaglio, C. Metallo, Paulo A. Gameiro, Karsten Hiller +5 more
2011Molecular Systems Biology94 citations Open access
Semantic Scholar
Polystyrene micro and nano-particles induce metabolic rewiring in normal human colon cells: A risk factor for human health.
M. Bonanomi, Noemi Salmistraro, D. Porro, A. Pinsino +2 more
2022Chemosphere93 citations Open access
Semantic Scholar
Radiosensitizing effect of curcumin-loaded lipid nanoparticles in breast cancer cells
L. Minafra, N. Porcino, V. Bravatà, D. Gaglio +13 more
2019Scientific Reports89 citations Open access
Semantic Scholar
Metformin and temozolomide, a synergic option to overcome resistance in glioblastoma multiforme models
S. Valtorta, A. Lo Dico, I. Raccagni, D. Gaglio +9 more
2017OncoTarget81 citations Open access
Semantic Scholar
Expression of transforming K-Ras oncogene affects mitochondrial function and morphology in mouse fibroblasts.
F. Chiaradonna, D. Gaglio, M. Vanoni, L. Alberghina
2006Biochimica et Biophysica Acta81 citations Open access
Semantic Scholar
Differentiation by nerve growth factor (NGF) involves mechanisms of crosstalk between energy homeostasis and mitochondrial remodeling
F. Martorana, D. Gaglio, Maria Rosaria Bianco, Federica Aprea +5 more
2018Cell Death and Disease71 citations Open access
Semantic Scholar
INTEGRATE: Model-based multi-omics data integration to characterize multi-level metabolic regulation
M. Di Filippo, Dario Pescini, B. Galuzzi, M. Bonanomi +6 more
2021bioRxiv66 citations Open access
Semantic Scholar
From cancer metabolism to new biomarkers and drug targets.
F. Chiaradonna, R. Moresco, C. Airoldi, D. Gaglio +4 more
2012Biotechnology Advances64 citations
Semantic Scholar
Computational Strategies for a System-Level Understanding of Metabolism
P. Cazzaniga, Chiara Damiani, D. Besozzi, R. Colombo +7 more
2014Metabolites58 citations Open access
Semantic Scholar
Titanium dioxide nanoparticles temporarily influence the sea urchin immunological state suppressing inflammatory-relate gene transcription and boosting antioxidant metabolic activity.
Andi Alijagic, D. Gaglio, Elisabetta Napodano, R. Russo +4 more
2020Journal of Hazardous Materials53 citations Open access
Semantic Scholar
Systems metabolomics: from metabolomic snapshots to design principles.
Chiara Damiani, D. Gaglio, E. Sacco, L. Alberghina +1 more
2020Current Opinion in Biotechnology52 citations Open access
Semantic Scholar
Differential Modulation of NF-κB in Neurons and Astrocytes Underlies Neuroprotection and Antigliosis Activity of Natural Antioxidant Molecules
F. Martorana, Maria Foti, A. Virtuoso, D. Gaglio +7 more
2019Oxidative Medicine and Cellular Longevity41 citations Open access
Semantic Scholar
Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation
R. Alfieri, Matteo Barberis, F. Chiaradonna, D. Gaglio +4 more
2009BMC Bioinformatics41 citations Open access
Semantic Scholar
Cancer cell growth and survival as a system-level property sustained by enhanced glycolysis and mitochondrial metabolic remodeling
L. Alberghina, D. Gaglio, C. Gelfi, R. Moresco +6 more
2012Front. Physio.40 citations Open access
Semantic Scholar
RAS and PKA pathways in cancer: new insight from transcriptional analysis.
F. Chiaradonna, C. Balestrieri, D. Gaglio, M. Vanoni
2008Frontiers in Bioscience40 citations Open access
Semantic Scholar
CDK12 promotes tumorigenesis but induces vulnerability to therapies inhibiting folate one-carbon metabolism in breast cancer
M. G. Filippone, D. Gaglio, R. Bonfanti, F. Tucci +24 more
2022Nature Communications38 citations Open access
Semantic Scholar
Zooming-in on cancer metabolic rewiring with tissue specific constraint-based models
M. Di Filippo, R. Colombo, Chiara Damiani, Dario Pescini +4 more
2016Comput. Biol. Chem.35 citations Open access
Semantic Scholar
Two high-rate pentose-phosphate pathways in cancer cells
Vanessa Cossu, M. Bonanomi, M. Bauckneht, S. Ravera +9 more
2020Scientific Reports34 citations Open access
Semantic Scholar
Gold nanoparticles coated with polyvinylpyrrolidone and sea urchin extracellular molecules induce transient immune activation.
Andi Alijagic, F. Barbero, D. Gaglio, Elisabetta Napodano +5 more
2021Journal of Hazardous Materials30 citations Open access
Semantic Scholar
Plastic leachate-induced toxicity during sea urchin embryonic development: Insights into the molecular pathways affected by PVC.
Periklis Paganos, C. Ullmann, D. Gaglio, M. Bonanomi +3 more
2022Science of the Total Environment26 citations Open access
Semantic Scholar
Safety Evaluation of TiO2 Nanoparticle-Based Sunscreen UV Filters on the Development and the Immunological State of the Sea Urchin Paracentrotus lividus
R. Catalano, Jérôme Labille, D. Gaglio, Andi Alijagic +4 more
2020Nanomaterials22 citations Open access
Semantic Scholar
Methionine Supplementation Affects Metabolism and Reduces Tumor Aggressiveness in Liver Cancer Cells
F. Tripodi, B. Badone, Marta Vescovi, Riccardo Milanesi +6 more
2020Cells21 citations Open access
Semantic Scholar
An Intricate Connection between Alternative Splicing and Phenotypic Plasticity in Development and Cancer
G. Biamonti, Lucia Infantino, D. Gaglio, Angela Amato
2019Cells21 citations Open access
Semantic Scholar
Transcriptomics and Metabolomics Integration Reveals Redox-Dependent Metabolic Rewiring in Breast Cancer Cells
M. Bonanomi, Noemi Salmistraro, G. Fiscon, F. Conte +13 more
2021Cancers20 citations Open access
Semantic Scholar
A Novel Strategy for Glioblastoma Treatment by Natural Bioactive Molecules Showed a Highly Effective Anti-Cancer Potential
A. Giammona, M. Commisso, M. Bonanomi, S. Remedia +5 more
2024Nutrients16 citations Open access
Semantic Scholar
Disruption of redox homeostasis for combinatorial drug efficacy in K-Ras tumors as revealed by metabolic connectivity profiling
D. Gaglio, M. Bonanomi, S. Valtorta, R. Bharat +16 more
2020Cancer & Metabolism15 citations Open access
Semantic Scholar
Divergent in vitro/in vivo responses to drug treatments of highly aggressive NIH-Ras cancer cells: a PET imaging and metabolomics-mass-spectrometry study
D. Gaglio, S. Valtorta, Marilena Ripamonti, M. Bonanomi +14 more
2016OncoTarget15 citations Open access
Semantic Scholar
A systems biology road map for the discovery of drugs targeting cancer cell metabolism.
L. Alberghina, D. Gaglio, R. Moresco, M. Gilardi +2 more
2014Current pharmaceutical design15 citations
Semantic Scholar
Fusion–fission–mitophagy cycling and metabolic reprogramming coordinate nerve growth factor (NGF)‐dependent neuronal differentiation
Ilaria Goglia, Ewelina Węglarz-Tomczak, Claudio Gioia, Yanhua Liu +9 more
2024The FEBS Journal12 citations Open access
Semantic Scholar
Fundamental Role of Pentose Phosphate Pathway within the Endoplasmic Reticulum in Glutamine Addiction of Triple-Negative Breast Cancer Cells
C. Marini, Vanessa Cossu, S. Carta, Elisa Greotti +13 more
2022Antioxidants12 citations Open access
Semantic Scholar
3D Modeling: Insights into the Metabolic Reprogramming of Cholangiocarcinoma Cells
Giorgia Ciufolini, Serena Zampieri, S. Cesaroni, Valentina Pasquale +9 more
2024Cells8 citations
Semantic Scholar
Glycolytic activity and in vitro effect of the pyruvate kinase activator AG‐946 in red blood cells from low‐risk myelodysplastic syndromes patients: A proof‐of‐concept study
B. Fattizzo, C. Vercellati, A. Marcello, Parija Patel +11 more
2024American journal of hematology/oncology7 citations Open access
Semantic Scholar
Production of recombinant human xCT (SLC7A11) and reconstitution in proteoliposomes for functional studies
M. Galluccio, Mariafrancesca Scalise, Gilda Pappacoda, Martina Scarpelli +3 more
2022Frontiers in Physiology6 citations Open access
Semantic Scholar
Safety Evaluation of TiO 2 Nanoparticle-Based Sunscreen UV Filters on the Development and the Immunological State of the Sea Urchin Paracentrotus lividus
R. Catalano, me Labille, D. Gaglio, Andi Alijagic +4 more
20206 citations
Semantic Scholar
Serine-Driven Metabolic Plasticity Drives Adaptive Resilience in Pancreatic Cancer Cells
M. Bonanomi, Sara Mallia, Mariafrancesca Scalise, Tecla Aramini +9 more
2025Antioxidants3 citations Open access
Semantic Scholar
Emodin and Aloe-Emodin Reduce Cell Growth and Disrupt Metabolic Plasticity in Human Melanoma Cells
Federica Baldassari, M. Bonanomi, Sara Mallia, Matteo Bonas +4 more
2025Nutrients3 citations Open access
Semantic Scholar
Mandatory role of endoplasmic reticulum in preserving NADPH regeneration in starved MDA-MB-231 breast cancer cells
Sonia Carta, Vanessa Cossu, Francesca Vitale, M. Bauckneht +9 more
2024Heliyon3 citations Open access
Semantic Scholar
Biochemical and Metabolomic Analysis of Glycolytic Activity in Red Blood Cells from Low-Risk Myelodysplastic Syndromes (LR-MDS) Patients and in-Vitro Effect of the Pyruvate Kinase Activator AG-946
B. Fattizzo, C. Vercellati, A. Marcello, Parija Patel +9 more
2023Blood2 citations Open access
Semantic Scholar
Early Metabolic Rewiring and Mitochondrial Remodeling in Response to Mitochondrial Impairment in a Rotenone Model of Parkinson’s Disease
Alissa Costantini, M. Bonanomi, G. Sala, A. Virtuoso +11 more
2026Cellular and molecular neurobiology1 citations Open access
Semantic Scholar
Disruption of redox homeostasis for combinatorial drug efficacy in K-Ras tumors as revealed by metabolic connectivity profiling
D. Gaglio, M. Bonanomi, S. Valtorta, R. Bharat +16 more
2020Cancer & Metabolism1 citations Open access
Semantic Scholar
Role of nutrient availability on proliferation and cell cycle excution of immortalized and kras transformed mouse fibroblastic
Degli Studi, di Milano-Bicocca, D. Gaglio, F. Chiaradonna
20091 citations
Semantic Scholar
An ensemble approach to the study of the emergence of metabolic and proliferative disorders via Flux Balance Analysis
Chiara Damiani, R. Colombo, S. Molinari, Dario Pescini +4 more
2013Italian Workshop on Artificial Life and Evolutionary Computation0 citations Open access
Semantic Scholar
High throughput metabolomics analysis in normal and K-Ras transformed murine fibroblasts
D. Gaglio, C. Metallo, F. Chiaradonna, C. Balestrieri +4 more
20100 citations
Semantic Scholar
UvA-DARE (Digital Academic Repository) A metabolic core model elucidates how enhanced utilization of glucose and glutamine, with enhanced glutamine-dependent lactate production, promotes cancer cell growth
Chiara Damiani, R. Colombo, D. Gaglio, F. Mastroianni +5 more
0 citations
Semantic Scholar

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L. Alberghina×20
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M. Vanoni×15
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F. Chiaradonna×10
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Chiara Damiani×8

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Dario Pescini×6

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Elisabetta Napodano×6

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C. Metallo — researcher profile on SciRah

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R. Colombo — researcher profile on SciRah