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E. Purlyte · SciRah

Researcher profile · Semantic Scholar

E. Purlyte

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E. Purlyte — researcher profile on SciRah

h-index: 8
Works: 13
Citations: 659

Most-cited papers

Rab29 activation of the Parkinson's disease‐associated LRRK2 kinase
E. Purlyte, H. S. Dhekne, Adil R. Sarhan, Rachel C. Gomez +6 more
2017EMBO Journal297 citations Open access
Semantic Scholar
Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding
Alexia F Kalogeropulou, E. Purlyte, F. Tonelli, S. Lange +5 more
2022bioRxiv112 citations Open access
Semantic Scholar
Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2
Dieter Waschbüsch, E. Purlyte, Prosenjit Pal, E. McGrath +2 more
2020Structure67 citations Open access
Semantic Scholar
Genome-wide screen reveals Rab12 GTPase as a critical activator of Parkinson’s disease-linked LRRK2 kinase
H. S. Dhekne, F. Tonelli, Wondwossen M. Yeshaw, C. A. Chiang +5 more
2023eLife54 citations Open access
Semantic Scholar
A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation
Edmundo G. Vides, Ayan Adhikari, C. A. Chiang, P. Lis +7 more
2022eLife51 citations Open access
Semantic Scholar
Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms
Asad U. Malik, A. Karapetsas, R. Nirujogi, S. Mathea +13 more
2020bioRxiv44 citations Open access
Semantic Scholar
Dual arginine recognition of LRRK2 phosphorylated Rab GTPases
Dieter Waschbüsch, E. Purlyte, A. R. Khan
2021Biophysical Journal11 citations Open access
Semantic Scholar
Genome-wide screen reveals Rab12 GTPase as a critical activator of pathogenic LRRK2 kinase
H. S. Dhekne, F. Tonelli, Wondwossen M. Yeshaw, C. A. Chiang +5 more
2023bioRxiv10 citations Open access
Semantic Scholar
A Feed-forward Pathway Drives LRRK2 kinase Membrane Recruitment and Activation
Edmundo G. Vides, Ayan Adhikari, C. A. Chiang, P. Lis +7 more
2022bioRxiv5 citations Open access
Semantic Scholar
1 A Feed-forward Pathway Drives LRRK 2 kinase Membrane Recruitment and Apparent Activation
Edmundo G. Vides, Ayan Adhikari, P. Lis, E. Purlyte +5 more
20224 citations
Semantic Scholar
Structural Basis for Rab8a GTPase Recruitment of RILPL2 via LRRK2-Mediated Phosphorylation of Switch 2
D. Waschbusch, E. Purlyte, Prosenjit Pal, E. McGrath +2 more
2020Social Science Research Network1 citations Open access
Semantic Scholar
Crystal structure of phosphorylated Rab8a in complex with the Rab-binding domain of RILPL2
D. Waschbusch, E. Purlyte, D. Alessi, A. R. Khan
20201 citations
Semantic Scholar
Structural basis for Rab8a GTPase recruitment of RILPL2 via LRRK2 phosphorylation of switch 2
Dieter Waschbüsch, E. Purlyte, Prosenjit Pal, E. McGrath +2 more
2019bioRxiv1 citations Open access
Semantic Scholar

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D. Alessi×9
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