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L. Bijnens · SciRah

Researcher profile · Semantic Scholar

L. Bijnens

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L. Bijnens — researcher profile on SciRah

h-index: 26
Works: 114
Citations: 2,610

Most-cited papers

FABIA: factor analysis for bicluster acquisition
S. Hochreiter, Ulrich Bodenhofer, M. Heusel, Andreas Mayr +10 more
2010Bioinform.342 citations Open access
Semantic Scholar
A broken promise: microbiome differential abundance methods do not control the false discovery rate
Stijn Hawinkel, F. Mattiello, L. Bijnens, O. Thas
2019Briefings Bioinform.176 citations
Semantic Scholar
Intergenerational transfer of antibiotic-perturbed microbiota enhances colitis in susceptible mice
Anjelique F. Schulfer, T. Battaglia, Yelina Alvarez, L. Bijnens +9 more
2017Nature Microbiology152 citations Open access
Semantic Scholar
I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data
W. Talloen, Djork-Arné Clevert, S. Hochreiter, D. Amaratunga +3 more
2007Bioinform.130 citations Open access
Semantic Scholar
A single early-in-life macrolide course has lasting effects on murine microbial network topology and immunity
Victoria E. Ruiz, T. Battaglia, Z. Kurtz, L. Bijnens +10 more
2017Nature Communications129 citations Open access
Semantic Scholar
Diffusion kurtosis imaging allows the early detection and longitudinal follow-up of amyloid-β-induced pathology
Jelle Praet, N. Manyakov, L. Muchene, Z. Mai +15 more
2018Alzheimer's Research & Therapy98 citations Open access
Semantic Scholar
Graphical Exploration of Gene Expression Data: A Comparative Study of Three Multivariate Methods
L. Wouters, H. Göhlmann, L. Bijnens, S. Kass +2 more
2003Biometrics94 citations
Semantic Scholar
Design and Analysis of Drug Combination Experiments
R. Straetemans, T. O'Brien, L. Wouters, J. van Dun +4 more
2005Biometrical journal. Biometrische Zeitschrift89 citations Open access
Semantic Scholar
A web application for sample size and power calculation in case-control microbiome studies
F. Mattiello, Bie M. P. Verbist, K. Faust, J. Raes +3 more
2016Bioinform.74 citations Open access
Semantic Scholar
Selection models and pattern‐mixture models to analyse longitudinal quality of life data subject to drop‐out
Bart Michiels, G. Molenberghs, L. Bijnens, T. Vangeneugden +1 more
2002Statistics in Medicine60 citations
Semantic Scholar
Individual patient data meta-analysis in cancer.
Mike Clarke, L. Stewart, J. Pignon, L. Bijnens
1998British Journal of Cancer49 citations Open access
Semantic Scholar
Individual patient-versus literature-based meta-analysis of survival data: time to event and event rate at a particular time can make a difference, an example based on head and neck cancer.
L. Duchateau, J. Pignon, L. Bijnens, Sylvie Bertin +2 more
2001Controlled Clinical Trials48 citations
Semantic Scholar
Overview of randomized perioperative polychemotherapy trials in women with early-stage breast cancer.
P. C. Clahsen, C. V. D. van de Velde, A. Goldhirsch, J. Rossbach +3 more
1997Journal of Clinical Oncology40 citations
Semantic Scholar
Application of the International Prognostic Scoring System for myelodysplastic syndromes.
Brigitte Maes, P. Meeus, L. Michaux, L. Bijnens +4 more
1999Annals of Oncology38 citations Open access
Semantic Scholar
A high‐dimensional joint model for longitudinal outcomes of different nature
C. Faes, M. Aerts, G. Molenberghs, H. Geys +2 more
2008Statistics in Medicine37 citations
Semantic Scholar
Validation of a longitudinally measured surrogate marker for a time-to-event endpoint
D. Renard, H. Geys, G. Molenberghs, T. Burzykowski +3 more
200334 citations
Semantic Scholar
Sequence count data are poorly fit by the negative binomial distribution
Stijn Hawinkel, J. Rayner, L. Bijnens, Olivier Thas
2020PLoS ONE33 citations Open access
Semantic Scholar
A combined analysis of EORTC/MRC randomized clinical trials for the prophylactic treatment of TaT1 bladder cancer. Eortc Genito-Urinary Tract Cancer Cooperative Group and the Medical Research Council Working Party on Superficial Bladder Cancer.
A. Pawinski, R. Sylvester, C. Bouffioux, K. Kurth +2 more
1996Acta urologica Belgica32 citations
Semantic Scholar
Statistical Applications in Genetics and Molecular Biology Testing for Trends in Dose-Response Microarray Experiments : A Comparison of Several Testing Procedures , Multiplicity and Resampling-Based Inference
Lin Dan, A. de Bondt, L. Bijnens
201131 citations
Semantic Scholar
Prediction of Human Oral Plasma Concentration-Time Profiles Using Preclinical Data
A. van den Bergh, Vikash K. Sinha, Ron Gilissen, R. Straetemans +4 more
2011Clinical Pharmacokinetics29 citations
Semantic Scholar
Transcriptional Response to Corticotropin-Releasing Factor in AtT-20 Cells
Pieter J. Peeters, H. Göhlmann, I. van den Wyngaert, S. Swagemakers +3 more
2004Molecular Pharmacology28 citations
Semantic Scholar
Filtering data from high-throughput experiments based on measurement reliability
W. Talloen, S. Hochreiter, L. Bijnens, A. Kasim +3 more
2010Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
IsoGene: An R Package for Analyzing Dose-response Studies in Microarray Experiments
S. Pramana, Lin Dan, Philippe Haldermans, Z. Shkedy +5 more
2010The R Journal22 citations Open access
Semantic Scholar
Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R
D. Lin, Z. Shkedy, D. Yekutieli, D. Amaratunga +1 more
201218 citations
Semantic Scholar
An Investigation on Performance of Significance Analysis of Microarray (SAM) for the Comparisons of Several Treatments with one Control in the Presence of Small‐variance Genes
D. Lin, Z. Shkedy, T. Burzykowski, R. Ion +6 more
2008Biometrical journal. Biometrische Zeitschrift18 citations Open access
Semantic Scholar
Linear Mixed Models and Missing Data
G. Molenberghs, L. Bijnens, D. Shaw
199718 citations
Semantic Scholar
A unified framework for unconstrained and constrained ordination of microbiome read count data
Stijn Hawinkel, F. Kerckhof, L. Bijnens, O. Thas
2018bioRxiv17 citations Open access
Semantic Scholar
Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R: Order-Restricted Analysis of Microarray Data
D. Lin, Z. Shkedy, D. Yekutieli, D. Amaratunga +1 more
201217 citations
Semantic Scholar
Statistical Applications in Genetics and Molecular Biology Informative or Noninformative Calls for Gene Expression : A Latent Variable Approach
L. Bijnens, H. Göhlmann, D. Amaratunga, S. Hochreiter +2 more
201117 citations
Semantic Scholar
Application of Semiparametric Mixed Models and Simultaneous Confidence Bands in a Cardiovascular Safety Experiment with Longitudinal Data
J. Maringwa, H. Geys, Z. Shkedy, C. Faes +5 more
2008Journal of Biopharmaceutical Statistics16 citations
Semantic Scholar
Use of Principal Component Analysis and the GE‐Biplot for the Graphical Exploration of Gene Expression Data
L. Wouters, H. Göhlmann, L. Bijnens, S. Kass +2 more
2005Biometrics16 citations
Semantic Scholar
Persistent improved results after adding vincristine and bleomycin to a cyclophosphamide/hydroxorubicin/Vm-26/prednisone combination (CHVmP) in stage III-IV intermediate- and high-grade non-Hodgkin's lymphoma. The EORTC Lymphoma Cooperative Group.
J. H. Meerwaldt, Patrice Carde, R. Somers, José Thomas +7 more
1997Annals of Oncology16 citations Open access
Semantic Scholar
Combined Models for Data from In Vitro–In Vivo Correlation Experiments
T. Jacobs, S. Rossenu, A. Dunne, G. Molenberghs +2 more
2008Journal of Biopharmaceutical Statistics15 citations
Semantic Scholar
ViVaMBC: estimating viral sequence variation in complex populations from illumina deep-sequencing data using model-based clustering
Bie M. P. Verbist, Lieven Clement, J. Reumers, K. Thys +7 more
2015BMC Bioinformatics14 citations Open access
Semantic Scholar
Univariate Versus Multivariate Surrogates in the Single-Trial Setting
W. Van der Elst, A. Alonso, H. Geys, P. Meyvisch +3 more
2019Statistics in Biopharmaceutical Research12 citations Open access
Semantic Scholar
Validation of biomarkers as surrogates for clinical endpoints
M. Buyse, T. Vangeneugden, L. Bijnens, D. Renard +3 more
200312 citations
Semantic Scholar
On the Use of Historical Control Data in Pre-Clinical Safety Studies
J. Maringwa, C. Faes, M. Aerts, Helena Geys +3 more
2007Journal of Biopharmaceutical Statistics9 citations
Semantic Scholar
A HIERARCHICAL BINOMIAL-POISSON MODEL FOR THE ANALYSIS OF A CROSSOVER DESIGN FOR CORRELATED BINARY DATA WHEN THE NUMBER OF TRIALS IS DOSE-DEPENDENT
Z. Shkedy, G. Molenberghs, H. van Craenendonck, T. Steckler +1 more
2005Journal of Biopharmaceutical Statistics9 citations
Semantic Scholar
Dose–Response Modeling Under Simple Order Restrictions Using Bayesian Variable Selection Methods
Martin Otava, Z. Shkedy, D. Lin, H. Göhlmann +3 more
20148 citations Open access
Semantic Scholar
Analysis of cross‐over designs with serial correlation within periods using semi‐parametric mixed models
J. Maringwa, H. Geys, Z. Shkedy, C. Faes +5 more
2008Statistics in Medicine8 citations
Semantic Scholar
Real-time gene expression analysis in human xenografts for evaluation of histone deacetylase inhibitors
A. Belien, S. de Schepper, W. Floren, Boudewijn Janssens +8 more
2006Molecular Cancer Therapeutics8 citations Open access
Semantic Scholar
Teaching Statistical Thinking to Life Scientists a Case-Based Approach
P. Vandenbroeck, L. Wouters, G. Molenberghs, J. V. Van Gestel +1 more
2006Journal of Biopharmaceutical Statistics8 citations
Semantic Scholar
Model-based joint visualization of multiple compositional omics datasets
Stijn Hawinkel, L. Bijnens, Kim-Anh Lê Cao, O. Thas
2020NAR Genomics and Bioinformatics7 citations Open access
Semantic Scholar
Classification of Trends in Dose-Response Microarray Experiments Using Information Theory Selection Methods~!2009-02-24~!2009-07-09~!2009-12-23~!
D. Lin, Z. Shkedy, T. Burzykowski, M. Aerts +6 more
20097 citations Open access
Semantic Scholar
Statistical detection of synergy: New methods and a comparative study
O. Thas, Annelies Tourny, Bie M. P. Verbist, Stijn Hawinkel +3 more
2021Pharmaceutical statistics6 citations
Semantic Scholar
Application and review of the separate ray model to investigate interaction effects.
R. Straetemans, L. Bijnens
2010Frontiers in Bioscience6 citations
Semantic Scholar
Psychotropic drug classification based on sleep–wake behaviour of rats
Kristien Wouters, A. Ahnaou, J. Abrahantes, G. Molenberghs +3 more
20076 citations
Semantic Scholar
GLMM approach to study the spatial and temporal evolution of spikes in the small intestine
C. Faes, M. Aerts, H. Geys, L. Bijnens +2 more
20066 citations
Semantic Scholar
Spatial determination of successive spikes in the isolated cat duodenum
W. J. E. P. Lammers, C. Faes, B. Stephen, L. Bijnens +2 more
2004Neurogastroenterology and Motility6 citations
Semantic Scholar
Controlling type I error rate for fast track drug development programmes
Wei-Chung J. Shih, P. Ouyang, H. Quan, Yong Lin +2 more
2003Statistics in Medicine6 citations
Semantic Scholar

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