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J. Griffin · SciRah

Researcher profile · Semantic Scholar

J. Griffin

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J. Griffin — researcher profile on SciRah

h-index: 83
Works: 373
Citations: 30K

Most-cited papers

Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes
L. Lotta, M. Pietzner, I. Stewart, L. Wittemans +31 more
2021Nature Genetics172 citations Open access
Semantic Scholar
Brown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
A. Whitehead, Fynn N. Krause, Amy Moran, A. Maccannell +16 more
2021Nature Communications143 citations Open access
Semantic Scholar
Lipid Remodeling in Hepatocyte Proliferation and Hepatocellular Carcinoma
Zoe Hall, Davide Chiarugi, E. Charidemou, J. Leslie +11 more
2020Hepatology140 citations Open access
Semantic Scholar
The cholesterol biosynthesis pathway regulates IL-10 expression in human Th1 cells
E. Perucha, R. Melchiotti, Jack A. Bibby, Wing Wu +14 more
2019Nature Communications125 citations Open access
Semantic Scholar
Assessing the causal association of glycine with risk of cardio-metabolic diseases
Laura B. L. Wittemans, L. Lotta, C. Oliver-Williams, I. Stewart +19 more
2019Nature Communications124 citations Open access
Semantic Scholar
Cytosine-5 RNA methylation links protein synthesis to cell metabolism
Nikoletta A. Gkatza, Cecilia Castro, Robert F. Harvey, Matthias Heiss +11 more
2019PLoS Biology124 citations Open access
Semantic Scholar
Metabolomic Analysis in Inflammatory Bowel Disease: A Systematic Review.
K. Gallagher, Alexandra Catesson, J. Griffin, E. Holmes +1 more
2020Journal of Crohn's & Colitis122 citations Open access
Semantic Scholar
Hepatic steatosis risk is partly driven by increased de novo lipogenesis following carbohydrate consumption
Francis W B Sanders, Animesh Acharjee, C. Walker, Luke Marney +16 more
2018Genome Biology107 citations Open access
Semantic Scholar
Dissemination and Analysis of the Quality Assurance (QA) and Quality Control (QC) Practices of LC-MS Based Untargeted Metabolomics Practitioners
Anne M. Evans, C. O'Donovan, M. Playdon, C. Beecher +23 more
2020Metabolomics106 citations Open access
Semantic Scholar
XBP-1 Remodels Lipid Metabolism to Extend Longevity
Soudabeh Imanikia, Ming Sheng, Cecilia Castro, J. Griffin +1 more
2019Cell Reports106 citations Open access
Semantic Scholar
The potential of Ion Mobility Mass Spectrometry for high-throughput and high-resolution lipidomics.
C. Hinz, Sonia Liggi, J. Griffin
2018Current Opinion in Chemical Biology90 citations Open access
Semantic Scholar
Fatty Acids Prevent Hypoxia-Inducible Factor-1α Signaling Through Decreased Succinate in Diabetes
M. Dodd, Sousa Fialho Maria da Luz, Claudia N. Montes Aparicio, M. Kerr +6 more
2018JACC: Basic to Translational Science81 citations Open access
Semantic Scholar
Inter-individual variability in the production of flavan-3-ol colonic metabolites: preliminary elucidation of urinary metabotypes
P. Mena, I. Ludwig, V. Tomatis, A. Acharjee +7 more
2019European Journal of Nutrition80 citations
Semantic Scholar
Deletion of Stearoyl-CoA Desaturase-1 From the Intestinal Epithelium Promotes Inflammation and Tumorigenesis, Reversed by Dietary Oleate.
Simon Ducheix, Claudia Peres, J. Härdfeldt, C. Frau +11 more
2018Gastroenterology67 citations Open access
Semantic Scholar
A combination of plasma phospholipid fatty acids and its association with incidence of type 2 diabetes: The EPIC-InterAct case-cohort study
F. Imamura, S. Sharp, A. Koulman, M. Schulze +40 more
2017PLoS Medicine65 citations Open access
Semantic Scholar
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle
B. McNally, D. Ashley, Lea Hänschke, H. Daou +12 more
2022Nature Communications64 citations Open access
Semantic Scholar
A comprehensive analysis of the faecal microbiome and metabolome of Strongyloides stercoralis infected volunteers from a non-endemic area
T. Jenkins, F. Formenti, Cecilia Castro, Chiara Piubelli +7 more
2018Scientific Reports63 citations Open access
Semantic Scholar
An Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors
Eric L. Harshfield, A. Koulman, D. Ziemek, Luke Marney +26 more
2019Journal of Proteome Research61 citations Open access
Semantic Scholar
Alphavirus-induced hyperactivation of PI3K/AKT directs pro-viral metabolic changes
Michela Mazzon, Cecilia Castro, B. Thaa, Lifeng Liu +6 more
2018PLoS Pathogens61 citations Open access
Semantic Scholar
Metabolomic and lipidomic plasma profile changes in human participants ascending to Everest Base Camp
K. O'Brien, R. Atkinson, Larissa Richardson, A. Koulman +10 more
2019Scientific Reports53 citations Open access
Semantic Scholar
nmrML: A Community Supported Open Data Standard for the Description, Storage, and Exchange of NMR Data.
Daniel Schober, D. Jacob, Michael Wilson, Joseph A. Cruz +28 more
2018Analytical Chemistry53 citations Open access
Semantic Scholar
Bone Morphogenetic Protein 8B Promotes The Progression of Non-Alcoholic Steatohepatitis
M. Vacca, J. Leslie, S. Virtue, B. Lam +18 more
2020Nature Metabolism52 citations Open access
Semantic Scholar
Italian cohort of patients affected by inflammatory bowel disease is characterised by variation in glycerophospholipid, free fatty acids and amino acid levels
A. Murgia, C. Hinz, Sonia Liggi, Júlia Dénes +9 more
2018Metabolomics52 citations Open access
Semantic Scholar
Non-alcoholic fatty liver disease is characterised by a reduced polyunsaturated fatty acid transport via free fatty acids and high-density lipoproteins (HDL)
Gabriele Mocciaro, M. Allison, Benjamin J. Jenkins, Vian Azzu +10 more
2023Molecular Metabolism50 citations Open access
Semantic Scholar
Metabolic phenotyping and cardiovascular disease: an overview of evidence from epidemiological settings
Aikaterini Iliou, E. Mikros, I. Karaman, Freya Elliott +3 more
2021Heart50 citations Open access
Semantic Scholar
Therapeutically expanded human regulatory T-cells are super-suppressive due to HIF1A induced expression of CD73
L. Jarvis, Daniel B. Rainbow, V. Coppard, S. Howlett +17 more
2020Communications Biology50 citations Open access
Semantic Scholar
Early detection of doxorubicin-induced cardiotoxicity in rats by its cardiac metabolic signature assessed with hyperpolarized MRI
Kerstin N. Timm, C. Perera, V. Ball, J. Henry +12 more
2020Communications Biology48 citations Open access
Semantic Scholar
A randomized 3-way crossover study indicates that high-protein feeding induces de novo lipogenesis in healthy humans
E. Charidemou, T. Ashmore, Xuefei Li, B. McNally +5 more
2019JCI Insight48 citations Open access
Semantic Scholar
A Combination of Metabolites Predicts Adherence to the Mediterranean Diet Pattern and Its Associations with Insulin Sensitivity and Lipid Homeostasis in the General Population: The Fenland Study, United Kingdom
T. Tong, A. Koulman, J. Griffin, N. Wareham +2 more
2019Journal of NutriLife47 citations Open access
Semantic Scholar
Suppression of insulin-induced gene 1 (INSIG1) function promotes hepatic lipid remodelling and restrains NASH progression
Vian Azzu, M. Vacca, Ioannis Kamzolas, Zoe Hall +15 more
2021Molecular Metabolism45 citations Open access
Semantic Scholar
KniMet: a pipeline for the processing of chromatography–mass spectrometry metabolomics data
Sonia Liggi, C. Hinz, Zoe Hall, M. L. Santoru +4 more
2018Metabolomics44 citations Open access
Semantic Scholar
Mapping Rora expression in resting and activated CD4+ T cells
Liora Haim-Vilmovsky, J. Henriksson, Jennifer A. Walker, Zhi-Chao Miao +19 more
2021PLoS ONE43 citations Open access
Semantic Scholar
A comprehensive UHPLC ion mobility QTOF method for profiling and quantification of eicosanoids, other oxylipins and fatty acids.
C. Hinz, Sonia Liggi, Gabriele Mocciaro, Stephanie M. Jung +8 more
2019Analytical Chemistry43 citations Open access
Semantic Scholar
Dysbiosis associated with acute helminth infections in herbivorous youngstock – observations and implications
L. Peachey, Cecilia Castro, Rebecca A. Molena, T. Jenkins +2 more
2019Scientific Reports39 citations Open access
Semantic Scholar
Vitamin C Cytotoxicity and Its Effects in Redox Homeostasis and Energetic Metabolism in Papillary Thyroid Carcinoma Cell Lines
Laura Tronci, G. Serreli, C. Piras, D. Frau +10 more
2021Antioxidants37 citations Open access
Semantic Scholar
The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination
C. McMurran, Alerie Guzman de la Fuente, R. Peñalva, Ofra Ben Menachem-Zidon +12 more
2019Proceedings of the National Academy of Sciences of the United States of America35 citations Open access
Semantic Scholar
Metabolic Profiling of the Diabetic Heart: Toward a Richer Picture
Alice P. Sowton, J. Griffin, A. Murray
2019Frontiers in Physiology35 citations Open access
Semantic Scholar
Effects of Germline VHL Deficiency on Growth, Metabolism, and Mitochondria.
S. Perrotta, D. Roberti, Debora Bencivenga, P. Corsetto +18 more
2020New England Journal of Medicine34 citations Open access
Semantic Scholar
Ice-Age Climate Adaptations Trap the Alpine Marmot in a State of Low Genetic Diversity
T. Gossmann, A. Shanmugasundram, S. Börno, L. Duvaux +19 more
2019Current Biology33 citations Open access
Semantic Scholar
Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes
Eva Lana-Elola, Heather L. Cater, Sheona Watson-Scales, Simon Greenaway +22 more
2021bioRxiv27 citations Open access
Semantic Scholar
Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure
Albert Kwok, I. Zvetkova, S. Virtue, Ineke Luijten +14 more
2020Molecular Metabolism27 citations Open access
Semantic Scholar
Downregulation of Keap1 Confers Features of a Fasted Metabolic State
Elena V. Knatko, M. Tatham, Ying Zhang, Cecilia Castro +8 more
2020iScience27 citations Open access
Semantic Scholar
Myc linked to dysregulation of cholesterol transport and storage in nonsmall cell lung cancer
Zoe Hall, Catherine H. Wilson, Deborah L. Burkhart, T. Ashmore +2 more
2020Journal of Lipid Research26 citations Open access
Semantic Scholar
Divergent trajectories of cellular bioenergetics, intermediary metabolism and systemic redox status in survivors and non-survivors of critical illness
H. McKenna, K. O'Brien, B. Fernandez, M. Minnion +9 more
2021Redox Biology24 citations Open access
Semantic Scholar
The consequences of lipid remodelling of adipocyte membranes being functionally distinct from lipid storage in obesity.
Ke-di Liu, Animesh Acharjee, C. Hinz, Sonia Liggi +10 more
2020Journal of Proteome Research24 citations Open access
Semantic Scholar
Histone acetyltransferase NAA40 modulates acetyl-CoA levels and lipid synthesis
E. Charidemou, Maria A. Tsiarli, Andria Theophanous, V. Yılmaz +4 more
2022BMC Biology23 citations Open access
Semantic Scholar
Twenty years of metabonomics: so what has metabonomics done for toxicology?
J. Griffin
2019Xenobiotica; the fate of foreign compounds in biological systems23 citations
Semantic Scholar
Changes in plasma phospholipid fatty acid profiles over 13 years and correlates of change: European Prospective Investigation into Cancer and Nutrition-Norfolk Study
Ju-Sheng Zheng, F. Imamura, S. Sharp, A. Koulman +6 more
2019American Journal of Clinical Nutrition22 citations Open access
Semantic Scholar
Cysteine and iron accelerate the formation of ribose-5-phosphate, providing insights into the evolutionary origins of the metabolic network structure
G. Piedrafita, S. Varma, Cecilia Castro, C. Messner +3 more
2021PLoS Biology18 citations Open access
Semantic Scholar
Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes
L. Lotta, M. Pietzner, I. Stewart, L. Wittemans +30 more
2020bioRxiv17 citations Open access
Semantic Scholar

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