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S. Moghaddam · SciRah

Researcher profile · Semantic Scholar

S. Moghaddam

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S. Moghaddam — researcher profile on SciRah

h-index: 29
Works: 129
Citations: 4,509

Most-cited papers

Muc5b Is Required for Airway Defense
Michelle G. Roy, A. Livraghi-Butrico, Ashley A. Fletcher, Melissa M. McElwee +39 more
2013Nature716 citations Open access
Semantic Scholar
Interleukin-17–induced neutrophil extracellular traps mediate resistance to checkpoint blockade in pancreatic cancer
Yu Zhang, Vidhi Chandra, E. Riquelme Sanchez, Prasanta Dutta +18 more
2020Journal of Experimental Medicine401 citations Open access
Semantic Scholar
T helper 17 cells play a critical pathogenic role in lung cancer
S. Chang, Seyedeh Golsar Mirabolfathinejad, Harshadadevi Katta, Amber M. Cumpian +4 more
2014Proceedings of the National Academy of Sciences of the United States of America315 citations Open access
Semantic Scholar
Airway Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease: Role of Cigarette Smoke Exposure.
M. Aghapour, Pourya Raee, S. Moghaddam, P. Hiemstra +1 more
2017American Journal of Respiratory Cell and Molecular Biology310 citations Open access
Semantic Scholar
Molecular and Cellular Pathobiology Oncogenic KRAS Confers Chemoresistance by Upregulating NRF 2
Sha-Sha Tao, Shue Wang, S. Moghaddam, Aikseng Ooi +3 more
2014264 citations
Semantic Scholar
IL-6 blockade reprograms the lung tumor microenvironment to limit the development and progression of K-ras mutant lung cancer
Maurício S. Caetano, Hui-Yuan Zhang, Amber M. Cumpian, L. Gong +13 more
2016Cancer Research189 citations Open access
Semantic Scholar
Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase
L. Gong, Amber M. Cumpian, Maurício S. Caetano, Cesar E Ochoa +6 more
2013Molecular Cancer162 citations Open access
Semantic Scholar
An atlas of epithelial cell states and plasticity in lung adenocarcinoma
Guang-Chun Han, Ansam Sinjab, Zahraa Rahal, Anne M Lynch +34 more
2024bioRxiv152 citations Open access
Semantic Scholar
Tumour and microenvironment crosstalk in NSCLC progression and response to therapy
Zahraa Rahal, Roy El Darzi, S. Moghaddam, Tina Cascone +1 more
2025Nature Reviews Clinical Oncology97 citations
Semantic Scholar
Resolving the spatial and cellular architecture of lung adenocarcinoma by multi-region single-cell sequencing
Ansam Sinjab, Guang-Chun Han, W. Treekitkarnmongkol, K. Hara +38 more
2021Cancer Prevention Research83 citations Open access
Semantic Scholar
Targeting IL-1β as an immunopreventive and therapeutic modality for K-ras–mutant lung cancer
Bo Yuan, M. Clowers, Walter V Velasco, S. Peng +13 more
2022JCI Insight77 citations Open access
Semantic Scholar
Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer
Maurício S. Caetano, M. Hassane, H. T. Van, Emmanuel Bugarin +16 more
2018Nature Communications66 citations Open access
Semantic Scholar
IL22 Promotes Kras Mutant Lung Cancer by Induction of a Pro-Tumor Immune Response and Protection of Stemness Properties
N. Khosravi, Maurício S. Caetano, Amber M. Cumpian, Nese Unver +15 more
2018Cancer immunology research60 citations Open access
Semantic Scholar
STAT3 restrains RANK- and TLR4-mediated signaling by suppressing expression of the E2 ubiquitin ligase Ubc13
Hui-Yuan Zhang, Hongbo Hu, N. Greeley, Jin Jin +10 more
2014Nature Communications50 citations Open access
Semantic Scholar
IL-6 mediates suppression of T and NK cells function in EMT-associated TKI-resistant EGFR mutant NSCLC
Sonia A Patel, M. Nilsson, Yan Yang, X. Le +13 more
2023Clinical Cancer Research45 citations Open access
Semantic Scholar
Reduced IL-6 levels and tumor-associated phospho-STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo-inositol
Nese Unver, O. Delgado, Kirubel T. Zeleke, Amber M. Cumpian +10 more
2017International Journal of Cancer40 citations Open access
Semantic Scholar
Understanding the Complexity of the Tumor Microenvironment in K-ras Mutant Lung Cancer: Finding an Alternative Path to Prevention and Treatment
Shanshan Deng, M. Clowers, Walter V Velasco, M. Ramos-Castañeda +1 more
2020Frontiers in Oncology37 citations Open access
Semantic Scholar
Requirement for MUC5AC in KRAS-dependent lung carcinogenesis.
Alison K. Bauer, Misha Umer, Vanessa L. Richardson, Amber M. Cumpian +18 more
2018JCI Insight37 citations Open access
Semantic Scholar
Multimodal Spatial-Omics Reveal Co-Evolution of Alveolar Progenitors and Proinflammatory Niches in Progression of Lung Precursor Lesions
F. Peng, Ansam Sinjab, Yibo Dai, W. Treekitkarnmongkol +45 more
2025Cancer Cell36 citations Open access
Semantic Scholar
KRAS-Mutant Lung Cancer: Targeting Molecular and Immunologic Pathways, Therapeutic Advantages and Restrictions
Nastaran Karimi, S. Moghaddam
2023Cells29 citations Open access
Semantic Scholar
Resolving the spatial and cellular architecture of lung adenocarcinoma by multi-region single-cell sequencing
Ansam Sinjab, Guang-Chun Han, K. Hara, W. Treekitkarnmongkol +38 more
2020bioRxiv29 citations Open access
Semantic Scholar
COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation
M. M. De la Garza, Amber M. Cumpian, Soudabeh Daliri, Susana Castro-Pando +13 more
2018OncoTarget27 citations Open access
Semantic Scholar
Inflammation mediated by gut microbiome alterations promotes lung cancer development and an immunosuppressed tumor microenvironment
Zahraa Rahal, Yue-Jiang Liu, F. Peng, Sujuan Yang +31 more
2024Cancer immunology research26 citations
Semantic Scholar
Toll-like receptors 2, 4, and 9 modulate promoting effect of COPD-like airway inflammation on K-ras-driven lung cancer through activation of the MyD88/NF-ĸB pathway in the airway epithelium
Walter V Velasco, N. Khosravi, Susana Castro-Pando, Nelly Torres-Garza +11 more
2023Frontiers in Immunology25 citations Open access
Semantic Scholar
Tumor necrosis factor links chronic obstructive pulmonary disease and K-ras mutant lung cancer through induction of an immunosuppressive pro-tumor microenvironment
L. Gong, Mauricio da Silva Caetano, Amber M. Cumpian, Soudabeh Daliri +6 more
2016Oncoimmunology22 citations Open access
Semantic Scholar
Premalignant Progression in the Lung: Knowledge Gaps and Novel Opportunities for Interception of Non–Small Cell Lung Cancer. An Official American Thoracic Society Research Statement
S. Moghaddam, Society Document, R. Savai, R. Salehi-Rad +19 more
2024American Journal of Respiratory and Critical Care Medicine18 citations Open access
Semantic Scholar
Ndfip1 Regulates Itch Ligase Activity and Airway Inflammation via UbcH7
Mahesh Kathania, Ming-Hui Zeng, V. Yadav, S. Moghaddam +2 more
2015Journal of Immunology17 citations Open access
Semantic Scholar
Interplay between Estrogen and Stat3/NF-κB Driven Immunomodulation in Lung Cancer.
Shanshan Deng, M. Ramos-Castañeda, Walter V Velasco, M. Clowers +14 more
2020Carcinogenesis16 citations Open access
Semantic Scholar
Mig-6 Deficiency Cooperates with Oncogenic Kras to Promote Mouse Lung Tumorigenesis
Jian Liu, Sung-Nam Cho, San-Pin Wu, Nili Jin +4 more
2017Lung Cancer16 citations Open access
Semantic Scholar
Augmented Lipocalin-2 Is Associated with Chronic Obstructive Pulmonary Disease and Counteracts Lung Adenocarcinoma Development
W. Treekitkarnmongkol, M. Hassane, Ansam Sinjab, Kyle Chang +28 more
202015 citations
Semantic Scholar
Immunotherapy with nebulized pattern recognition receptor agonists restores severe immune paralysis and improves outcomes in mice with influenza-associated pulmonary aspergillosis
J. Pantaléon-García, S. Wurster, N. Albert, U. Bharadwaj +13 more
2024bioRxiv14 citations Open access
Semantic Scholar
OBIF: an omics-based interaction framework to reveal molecular drivers of synergy
J. Pantaléon-García, V. Kulkarni, T. Reese, S. Wali +10 more
2022NAR Genomics and Bioinformatics12 citations Open access
Semantic Scholar
Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes
Casey T. Finnicum, Zahraa Rahal, M. Hassane, W. Treekitkarnmongkol +13 more
2022International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Augmented Lipocalin-2 is Associated with COPD and Counteracts Lung Adenocarcinoma Development.
W. Treekitkarnmongkol, M. Hassane, Ansam Sinjab, Kyle Chang +28 more
2020American Journal of Respiratory and Critical Care Medicine11 citations Open access
Semantic Scholar
Cell Type-Specific Roles of STAT3 Signaling in the Pathogenesis and Progression of K-ras Mutant Lung Adenocarcinoma
M. Clowers, S. Moghaddam
2022Cancers9 citations Open access
Semantic Scholar
Single-Cell Expression Landscape of SARS-CoV-2 Receptor ACE2 and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients
Guang-Chun Han, Ansam Sinjab, K. Hara, W. Treekitkarnmongkol +27 more
2021Cancers9 citations Open access
Semantic Scholar
A pilot double-blind, randomized, placebo-controlled trial of curcumin/bioperine for lung cancer chemoprevention in patients with chronic obstructive pulmonary disease
A. Sharafkhaneh, J. Lee, Diane D. Liu, R. Katz +13 more
20138 citations Open access
Semantic Scholar
Cigarette smoke induces angiogenic activation in the cancer field through dysregulation of an endothelial microRNA
Asawari Korde, Anuradha Ramaswamy, S. Anderson, Lei-Yang Jin +12 more
2025Communications Biology6 citations Open access
Semantic Scholar
Correction: Oncogenic KRAS Confers Chemoresistance by Upregulating NRF2.
Sha-Sha Tao, Shue Wang, S. Moghaddam, Aikseng Ooi +3 more
2019Cancer Research6 citations Open access
Semantic Scholar
Promoting effect of neutrophils on lung tumorigenesis is mediated by CXCR2 and neutrophil elastase
Lei Gong, Amber M. Cumpian, Maurício S. Caetano, Cesar E Ochoa +6 more
2013Molecular Cancer6 citations Open access
Semantic Scholar
Pancreatic Epithelial IL17/IL17RA Signaling Drives B7-H4 Expression to Promote Tumorigenesis
Susana Castro-Pando, Rian M Howell, Le Li, M. Mascaró +11 more
2024Cancer immunology research5 citations Open access
Semantic Scholar
Single-cell analysis of human lung epithelia reveals concomitant expression of the SARS-CoV-2 receptor ACE2 with multiple virus receptors and scavengers in alveolar type II cells
Guang-Chun Han, Ansam Sinjab, W. Treekitkarnmongkol, Patrick J. Brennan +28 more
2020bioRxiv5 citations Open access
Semantic Scholar
Selective inhibition of canonical STAT3 signaling suppresses K-ras mutant lung tumorigenesis and reinvigorates anti-tumor immunity
M. Clowers, Zahraa Rahal, Sungnam Cho, A. Krishna +23 more
2025Frontiers in Immunology3 citations Open access
Semantic Scholar
Cigarette smoke exposure accelerates AML progression in FLT3-ITD models
Mary Figueroa, Hua-Xian Ma, M. Alfayez, D. Morales-Mantilla +11 more
2023Blood Advances3 citations Open access
Semantic Scholar
Comparative effects of combustible cigarette versus electronic cigarette exposures on KRAS mutant lung cancer promotion
Walter V Velasco, M. T. Grimaldo, Nastaran Karimi, M. Clowers +23 more
2025Neoplasia2 citations Open access
Semantic Scholar
Author Correction: An atlas of epithelial cell states and plasticity in lung adenocarcinoma
Guang-Chun Han, Ansam Sinjab, Zahraa Rahal, Anne M Lynch +34 more
2024Nature2 citations Open access
Semantic Scholar
Repurposing of the Macrolide Antibiotic Clarithromycin for the Prevention of Lung Cancer
Shanshan Deng, Tabish Hussain, T. Bartelli, M. Sebastian +12 more
2025Molecular Cancer Therapeutics1 citations
Semantic Scholar
The multipotential effect of microbiome in lung cancer development and progression.
Nastaran Karimi, Angélica Baca De Anda, Rachel Y. H. Yang, Emre Aksan +2 more
2025International Review of Cell and Molecular Biology1 citations
Semantic Scholar
Abstract 5104: Targeting IL-1B synergizes with PD-1 blockade for enhanced T and B cell immune responses and inhibition of early lung cancer development
W. Treekitkarnmongkol, Guang-Chun Han, Zahraa Rahal, Ji-Ping Feng +10 more
2023Cancer Research1 citations
Semantic Scholar
Abstract 113: An atlas of epithelial cell states and plasticity in lung adenocarcinoma
Guang-Chun Han, Ansam Sinjab, W. Treekitkarnmongkol, Zahraa Rahal +30 more
2023Cancer Research1 citations
Semantic Scholar

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