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Sangsu Bae · SciRah

Researcher profile · Semantic Scholar

Sangsu Bae

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Sangsu Bae — researcher profile on SciRah

h-index: 37
Works: 124
Citations: 9,573

Most-cited papers

DNA-free two-gene knockout in Chlamydomonas reinhardtii via CRISPR-Cas9 ribonucleoproteins
Kwangryul Baek, Duk-Hyoung Kim, Jooyeon Jeong, S. Sim +4 more
2016Scientific Reports306 citations Open access
Semantic Scholar
Direct observation of DNA target searching and cleavage by CRISPR-Cas12a
Yongmoon Jeon, You-Hee Choi, Y. Jang, Jihyeon Yu +9 more
2018Nature Communications204 citations Open access
Semantic Scholar
Web-based design and analysis tools for CRISPR base editing
Gue-Ho Hwang, Jeongbin Park, Kayeong Lim, Sunghyun Kim +6 more
2018BMC Bioinformatics184 citations Open access
Semantic Scholar
Current Status and Challenges of DNA Base Editing Tools.
You Kyeong Jeong, Beomjong Song, Sangsu Bae
2020Molecular Therapy132 citations Open access
Semantic Scholar
Selective disruption of an oncogenic mutant allele by CRISPR/Cas9 induces efficient tumor regression
T. Koo, A. Yoon, Hee-Yeon Cho, Sangsu Bae +2 more
2017Nucleic Acids Research122 citations Open access
Semantic Scholar
Adenine base editors catalyze cytosine conversions in human cells
H. Kim, You Kyeong Jeong, J. Hur, Jin-Soo Kim +1 more
2019Nature Biotechnology117 citations
Semantic Scholar
Photoautotrophic production of macular pigment in a Chlamydomonas reinhardtii strain generated by using DNA‐free CRISPR‐Cas9 RNP‐mediated mutagenesis
Kwangryul Baek, Jihyeon Yu, Jooyeon Jeong, S. Sim +2 more
2018Biotechnology and Bioengineering113 citations
Semantic Scholar
Adenine base editor engineering reduces editing of bystander cytosines
You Kyeong Jeong, Seokhoon Lee, Gue-Ho Hwang, Sung-Ah Hong +4 more
2021Nature Biotechnology104 citations Open access
Semantic Scholar
CUT-PCR: CRISPR-mediated, ultrasensitive detection of target DNA using PCR
Seung-Hwan Lee, Jiyoung Yu, Gue-Ho Hwang, Sunghyun Kim +8 more
2017Oncogene100 citations Open access
Semantic Scholar
PE-Designer and PE-Analyzer: web-based design and analysis tools for CRISPR prime editing
Gue-Ho Hwang, You Kyeong Jeong, Omer Habib, Sung-Ah Hong +3 more
2021Nucleic Acids Res.96 citations Open access
Semantic Scholar
Simultaneous targeting of duplicated genes in Petunia protoplasts for flower color modification via CRISPR-Cas9 ribonucleoproteins
Jihyeon Yu, Luhua Tu, Saminathan Subburaj, Sangsu Bae +1 more
2020Plant Cell Reports83 citations
Semantic Scholar
Comprehensive analysis of prime editing outcomes in human embryonic stem cells
Omer Habib, Gizem Habib, Gue-Ho Hwang, Sangsu Bae
2021bioRxiv72 citations Open access
Semantic Scholar
Adenine base editing and prime editing of chemically derived hepatic progenitors rescue genetic liver disease.
Yohan Kim, Sung-Ah Hong, Jihyeon Yu, Jeongyun Eom +9 more
2021Cell Stem Cell63 citations Open access
Semantic Scholar
Analysis of NHEJ-Based DNA Repair after CRISPR-Mediated DNA Cleavage
Beomjong Song, Soyeon Yang, Gue-Ho Hwang, Jihyeon Yu +1 more
2021International Journal of Molecular Sciences51 citations Open access
Semantic Scholar
Therapeutic base editing and prime editing of COL7A1 mutations in recessive dystrophic epidermolysis bullosa
Sung-Ah Hong, Song-Ee Kim, Ayeong Lee, Gue-Ho Hwang +5 more
2022Molecular Therapy48 citations Open access
Semantic Scholar
Mg2+-dependent conformational rearrangements of CRISPR-Cas12a R-loop complex are mandatory for complete double-stranded DNA cleavage
Heyjin Son, Jaeil Park, Injoo Hwang, Youngri Jung +2 more
2021Proceedings of the National Academy of Sciences of the United States of America46 citations Open access
Semantic Scholar
Cas-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cas9
Jeongbin Park, Jin-Soo Kim, Sangsu Bae
2016Bioinform.46 citations Open access
Semantic Scholar
Visual function restoration in a mouse model of Leber congenital amaurosis via therapeutic base editing
D. Jo, Hyeon-Ki Jang, Sik-Cho Chang, Jun-Hee Han +4 more
2022Molecular Therapy: Nucleic Acids43 citations Open access
Semantic Scholar
Current trends in gene recovery mediated by the CRISPR-Cas system
Hyeon-Ki Jang, Beomjong Song, Gue-Ho Hwang, Sangsu Bae
2020Experimental and Molecular Medicine43 citations Open access
Semantic Scholar
CRISPR-Pass: Gene Rescue of Nonsense Mutations Using Adenine Base Editors
Choongil Lee, Dong Hyun Jo, Gue-Ho Hwang, Jihyeon Yu +5 more
2019bioRxiv42 citations Open access
Semantic Scholar
CRISPR/Cas9-targeted mutagenesis of F3′H, DFR and LDOX, genes related to anthocyanin biosynthesis in black rice (Oryza sativa L.)
Y. Jung, H. Lee, Jong Hee Kim, Dong Hyen Kim +4 more
2019Plant Biotechnology Reports42 citations
Semantic Scholar
CRISPR/Cas9-mediated gene knockout screens and target identification via whole-genome sequencing uncover host genes required for picornavirus infection
H. Kim, Kyungjin Lee, Sangsu Bae, Jeongbin Park +7 more
2017Journal of Biological Chemistry40 citations Open access
Semantic Scholar
Digenome-seq web tool for profiling CRISPR specificity
Jeongbin Park, L. Childs, Daesik Kim, Gue-Ho Hwang +4 more
2017Nature Methods40 citations
Semantic Scholar
Knockout of SlMS10 Gene (Solyc02g079810) Encoding bHLH Transcription Factor Using CRISPR/Cas9 System Confers Male Sterility Phenotype in Tomato
Y. Jung, D. G. Kim, H. Lee, K. Nam +5 more
2020Plants39 citations Open access
Semantic Scholar
Arabidopsis ATXR2 represses de novo shoot organogenesis in the transition from callus to shoot formation.
Kyounghee Lee, Ok-Sun Park, J. Go, Jihyeon Yu +5 more
2021Cell Reports38 citations Open access
Semantic Scholar
Deletion of the chloroplast LTD protein impedes LHCI import and PSI–LHCI assembly in Chlamydomonas reinhardtii
Jooyeon Jeong, Kwangryul Baek, Jihyeon Yu, H. Kirst +5 more
2017Journal of Experimental Botany38 citations Open access
Semantic Scholar
Construction of non-canonical PAM-targeting adenosine base editors by restriction enzyme-free DNA cloning using CRISPR-Cas9
You Kyeong Jeong, Jihyeon Yu, Sangsu Bae
2019Scientific Reports29 citations Open access
Semantic Scholar
Acquisition of seed dormancy breaking in rice (Oryza sativa L.) via CRISPR/Cas9-targeted mutagenesis of OsVP1 gene
Y. Jung, H. Lee, Sangsu Bae, Jong Hee Kim +6 more
2019Plant Biotechnology Reports29 citations
Semantic Scholar
The freshwater water flea Daphnia magna NIES strain genome as a resource for CRISPR/Cas9 gene targeting: The glutathione S-transferase omega 2 gene.
Eunjin Byeon, Min-Sub Kim, Duck-Hyun Kim, Yoseop Lee +11 more
2021Aquatic Toxicology28 citations
Semantic Scholar
CReVIS-Seq: A highly accurate and multiplexable method for genome-wide mapping of lentiviral integration sites
H. Kim, Gue-Ho Hwang, Hyomin K. Lee, Taegeun Bae +6 more
2021Molecular Therapy: Methods & Clinical Development27 citations Open access
Semantic Scholar
CRISPR-Cas9 Screening of Kaposi’s Sarcoma-Associated Herpesvirus-Transformed Cells Identifies XPO1 as a Vulnerable Target of Cancer Cells
M. Gruffaz, Hongfeng Yuan, W. Meng, H. Liu +5 more
2019mBio27 citations Open access
Semantic Scholar
Transcriptome and Metabolite Profiling of Tomato SGR-Knockout Null Lines Using the CRISPR/Cas9 System
Jin Young Kim, Jong Hee Kim, Young-Hee Jang, Jihyeon Yu +5 more
2022International Journal of Molecular Sciences26 citations Open access
Semantic Scholar
Cpf1-Database: web-based genome-wide guide RNA library design for gene knockout screens using CRISPR-Cpf1
Jeongbin Park, Sangsu Bae
2018Bioinform.26 citations Open access
Semantic Scholar
ID3 regulates the MDC1-mediated DNA damage response in order to maintain genome stability
Jung-Hee Lee, S. Park, G. Hariharasudhan, Min-Ji Kim +8 more
2017Nature Communications26 citations Open access
Semantic Scholar
Generation and Transcriptome Profiling of Slr1-d7 and Slr1-d8 Mutant Lines with a New Semi-Dominant Dwarf Allele of SLR1 Using the CRISPR/Cas9 System in Rice
Y. Jung, Jong Hee Kim, H. Lee, D. G. Kim +4 more
2020International Journal of Molecular Sciences23 citations Open access
Semantic Scholar
Safe scarless cassette-free selection of genome-edited human pluripotent stem cells using temporary drug resistance.
Keun-Tae Kim, Ju-Chan Park, Hyeon-Ki Jang, Haeseung Lee +9 more
2020Biomaterials22 citations
Semantic Scholar
CRISPR-sub: Analysis of DNA substitution mutations caused by CRISPR-Cas9 in human cells
Gue-Ho Hwang, Jihyeon Yu, Soyeon Yang, W. Son +4 more
2020Computational and Structural Biotechnology Journal21 citations Open access
Semantic Scholar
Transcriptomic and physiological analysis of OsCAO1 knockout lines using the CRISPR/Cas9 system in rice
Y. Jung, H. Lee, Jihyeon Yu, Sangsu Bae +2 more
2020Plant Cell Reports20 citations
Semantic Scholar
Web-Based CRISPR Toolkits: Cas-OFFinder, Cas-Designer, and Cas-Analyzer.
Gue-Ho Hwang, Jin-Soo Kim, Sangsu Bae
2021Methods in molecular biology19 citations
Semantic Scholar
In vivo gene editing via homology-independent targeted integration for adrenoleukodystrophy treatment.
Sung-Ah Hong, J. Seo, Soohyun Wi, Eul Sik Jung +7 more
2021Molecular Therapy19 citations Open access
Semantic Scholar
Anti-Atherogenic Effect of Stem Cell Nanovesicles Targeting Disturbed Flow Sites.
Jeong-Kee Yoon, Dae-Hyun Kim, Mi-Lan Kang, Hyeon-Ki Jang +15 more
2020Small19 citations Open access
Semantic Scholar
Increased PKMζ activity impedes lateral movement of GluA2-containing AMPA receptors
Nam-Kyung Yu, Heesoo Uhm, Jaehoon Shim, Jun-Hyeok Choi +4 more
2017Molecular Brain19 citations Open access
Semantic Scholar
Extru-seq: a method for predicting genome-wide Cas9 off-target sites with advantages of both cell-based and in vitro approaches
Jeonghun Kwon, Minyoung Kim, Woochang Hwang, Anna Jo +12 more
2023Genome Biology18 citations Open access
Semantic Scholar
Questioning unexpected CRISPR off-target mutations in vivo
Sang-Tae Kim, Jeongbin Park, Daesik Kim, Kyoungmi Kim +3 more
2017bioRxiv18 citations Open access
Semantic Scholar
SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells
Mei-Lan He, Hongfeng Yuan, Brandon Tan, Rosemary Bai +5 more
2016OncoTarget18 citations Open access
Semantic Scholar
Targeted genome editing, an alternative tool for trait improvement in horticultural crops
Saminathan Subburaj, Luhua Tu, Yong-Tae Jin, Sangsu Bae +3 more
2016Horticulture Environment and Biotechnology18 citations Open access
Semantic Scholar
LPA2 protein is involved in photosystem II assembly in Chlamydomonas reinhardtii
M. Cecchin, Jooyeon Jeong, W. Son, Minjae Kim +8 more
2021The Plant Journal17 citations Open access
Semantic Scholar
Reduced Ethylene Production in Tomato Fruits upon CRSPR/Cas9-mediated LeMADS-RIN Mutagenesis
Yu-Jin Jung, Geung-Joo Lee, Sangsu Bae, K. Kang
201817 citations Open access
Semantic Scholar
Direct Observation of DNA Target Searching and Cleavage by CRISPR-Cas12a
Yongmoon Jeon, You-Hee Choi, Y. Jang, Jiyoung Gu +3 more
2019Biophysical Journal16 citations Open access
Semantic Scholar
MutSα and MutSβ as size-dependent cellular determinants for prime editing in human embryonic stem cells
Ju-Chan Park, Yun Kim, Jun-Hee Han, Dayeon Kim +5 more
2023Molecular Therapy: Nucleic Acids15 citations Open access
Semantic Scholar

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