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M. W. Grol · SciRah

Researcher profile · Semantic Scholar

M. W. Grol

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M. W. Grol — researcher profile on SciRah

h-index: 15
Works: 36
Citations: 781

Most-cited papers

Expression, signaling, and function of P2X7 receptors in bone
M. W. Grol, N. Panupinthu, J. Korcok, Stephen M. Sims +1 more
2009Purinergic Signalling Purinergic Signalling112 citations Open access
Semantic Scholar
Gene therapy for repair and regeneration of bone and cartilage
M. W. Grol, Brendan H. Lee
2018Current opinion in pharmacology (Print)77 citations
Semantic Scholar
Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice
Kim L. Beaucage, Andrew Xiao, S. Pollmann, M. W. Grol +5 more
2013Purinergic Signalling Purinergic Signalling74 citations Open access
Semantic Scholar
Disease‐Modifying Osteoarthritis Treatment With Interleukin‐1 Receptor Antagonist Gene Therapy in Small and Large Animal Models
A. Nixon, M. W. Grol, Hayley M. Lang, M. Z. Ruan +8 more
2018Arthritis & Rheumatology72 citations
Semantic Scholar
Reinforcement of flowable dental composites with titanium dioxide nanotubes.
Manal O. Dafar, M. W. Grol, Peter B. Canham, S. J. Dixon +1 more
2016Dental Materials59 citations Open access
Semantic Scholar
Combinatorial Prg4 and Il-1ra Gene Therapy Protects Against Hyperalgesia and Cartilage Degeneration in Post-Traumatic Osteoarthritis
A. Stone, M. W. Grol, M. Z. Ruan, B. Dawson +7 more
2019Human Gene Therapy52 citations Open access
Semantic Scholar
Finite-Element Modeling of Viscoelastic Cells During High-Frequency Cyclic Strain
J. Milner, M. W. Grol, Kim L. Beaucage, S. Dixon +1 more
2012Journal of Functional Biomaterials43 citations Open access
Semantic Scholar
Effects of Aspirin on Growth Factor Release From Freshly Isolated Leukocyte-Rich Platelet-Rich Plasma in Healthy Men: A Prospective Fixed-Sequence Controlled Laboratory Study
P. Jayaram, P. Yeh, Shiv J Patel, Racel Cela +3 more
2019American Journal of Sports Medicine41 citations
Semantic Scholar
Leukocyte-Dependent Effects of Platelet-Rich Plasma on Cartilage Loss and Thermal Hyperalgesia in a Mouse Model of Post-Traumatic Osteoarthritis
P. Jayaram, Christina Liu, B. Dawson, Shamika Ketkar +3 more
2020Osteoarthritis and Cartilage36 citations Open access
Semantic Scholar
P2X₇-mediated calcium influx triggers a sustained, PI3K-dependent increase in metabolic acid production by osteoblast-like cells.
M. W. Grol, Irene Zelner, S. Dixon
2012American Journal of Physiology. Endocrinology and Metabolism36 citations
Semantic Scholar
Modeling Interactions among Individual P2 Receptors to Explain Complex Response Patterns over a Wide Range of ATP Concentrations
Shu Xing, M. W. Grol, P. Grutter, S. Dixon +1 more
2016Frontiers in Physiology33 citations Open access
Semantic Scholar
P2 receptor networks regulate signaling duration over a wide dynamic range of ATP concentrations
M. W. Grol, A. Pereverzev, S. M. Sims, S. Dixon
2013Journal of Cell Science31 citations
Semantic Scholar
The Evolving Landscape of Gene Therapy Strategies for The Treatment of Osteoarthritis.
M. W. Grol
2024Osteoarthritis and Cartilage27 citations Open access
Semantic Scholar
P2X7 nucleotide receptor signaling potentiates the Wnt/β-catenin pathway in cells of the osteoblast lineage
M. W. Grol, P. J. Brooks, A. Pereverzev, S. Dixon
2016Purinergic Signalling Purinergic Signalling20 citations Open access
Semantic Scholar
Tendon and Motor Phenotypes in the Crtap-/- Mouse Model of Recessive Osteogenesis Imperfecta
M. W. Grol, Nele A. Haelterman, Joohyun Lim, Elda M. Munivez +8 more
2020bioRxiv15 citations Open access
Semantic Scholar
Diet-induced obesity leads to behavioral indicators of pain preceding structural joint damage in wild-type mice
G. Kerr, Bethia To, Ian White, M. Millecamps +4 more
2020Arthritis Research & Therapy13 citations Open access
Semantic Scholar
Localized chondro-ossification underlies joint dysfunction and motor deficits in the Fkbp10 mouse model of osteogenesis imperfecta
Joohyun Lim, C. Lietman, M. W. Grol, A. Castellon +10 more
2021Proceedings of the National Academy of Sciences of the United States of America10 citations Open access
Semantic Scholar
P 2 X 7-mediated calcium influx triggers a sustained , PI 3 K-dependent increase in metabolic acid production by osteoblast-like cells
M. W. Grol, Irene Zelner, S. Dixon
20127 citations
Semantic Scholar
Cyclic AMP regulates extracellular matrix gene expression and metabolism in cultured primary rat chondrocytes.
J. Rockel, M. W. Grol, S. Bernier, A. Leask
2009Matrix Biology7 citations
Semantic Scholar
Editorial: The immune system and inflammation in musculoskeletal health, aging, and disease
G. Baht, M. W. Grol
2023Frontiers in Immunology4 citations Open access
Semantic Scholar
Pannexin 3 deletion in mice results in knee osteoarthritis and intervertebral disc degeneration after forced treadmill running
Brent Wakefield, Justin Tang, J. L. Hutchinson, Rehanna Kanji +5 more
2023bioRxiv4 citations Open access
Semantic Scholar
PACS-1 Interacts with TRPC3 and ESyt1 to Mediate Protein Trafficking while Promoting SOCE and Cooperatively Regulating Hormone Secretion
Steven M. Trothen, Jack E. Teplitsky, Ryan E. Armstong, Rong-Xuan Zang +5 more
2024ACS Omega3 citations Open access
Semantic Scholar
Prospects of Gene Therapy for Skeletal Diseases
M. W. Grol, A. Stone, M. Z. Ruan, K. Guse +1 more
20182 citations
Semantic Scholar
P2X7 Nucleotide Receptor Signaling in Osteoblasts
M. W. Grol
20132 citations
Semantic Scholar
Severe osteoarthritis in aged PANX3 knockout mice: implications for a novel primary osteoarthritis model
Brent Wakefield, Justin Tang, Julián Balanta-Melo, J. L. Hutchinson +10 more
2025bioRxiv1 citations Open access
Semantic Scholar
Fibroblast and Myeloid Cells with High Mitochondrial RNA Content Represent Biologically Significant Populations within the OA Synovium.
Wesley Tran, Garth Blackler, Rebecca Luo, C. Appleton +1 more
2025Osteoarthritis and Cartilage1 citations Open access
Semantic Scholar
Interleukin-1 receptor antagonist gene therapy prevents and delays surgically-induced osteoarthritis in small and large animal models
M. W. Grol, A. Nixon, Hayley M. Lang, M. Z. Ruan +5 more
20181 citations Open access
Semantic Scholar
Receptor-independent effects of 2′(3′)-O-(4-benzoylbenzoyl)ATP triethylammonium salt on cytosolic pH
J. P. Reyes, M. W. Grol, S. M. Sims, S. Dixon
2013Purinergic Signalling Purinergic Signalling1 citations Open access
Semantic Scholar
Distinct P2 receptors initiate intracellular signaling involved in mechanotransduction in tenocytes.
Ryan E Armstrong, Mayeesha N. Khan, M. W. Grol
2026American Journal of Physiology - Cell Physiology0 citations Open access
Semantic Scholar
Acute TGFα drives OA-associated transcriptional and metabolic remodelling in primary chondrocytes
Emily L. White, E. Day, C. Appleton, M. W. Grol +1 more
2026Osteoarthritis and Cartilage Open0 citations Open access
Semantic Scholar
Anabolic steroid use increases intervertebral disc height and reduces vertebral subchondral bone volume in the lumbar spine in male mice
J. L. Hutchinson, E. Hadzic, Shelby Oke, Diana I. Quinonez +6 more
2026JBMR Plus0 citations Open access
Semantic Scholar
Role of soft tissue and bone interactions in the developmental integration and modularity of the skull in neural crest‐specific gap junction alpha‐1 knockout mice
Alyssa C. Moore, Madeline S G Tourigny, D. Quinonez, Kevin Barr +2 more
2025The Anatomical Record0 citations Open access
Semantic Scholar
Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta
M. W. Grol, Nele A. Haelterman, Joohyun Lim, Elda M. Munivez +10 more
2021eLife0 citations Open access
Semantic Scholar
Author response: Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta
M. W. Grol, Nele A. Haelterman, Joohyun Lim, Elda M. Munivez +10 more
20210 citations Open access
Semantic Scholar
collagen gels ATP reduces gel compaction in osteoblast-populated
J. Qi, L. Chi, J. Faber, B. Koller +4 more
20150 citations
Semantic Scholar
P2 Receptors Mediate Nucleotide-Induced Calcium Signalling and Gene Expression Changes in Tenocytes – Implications for Tendon Mechanotransduction
Ryan T. Armstrong, M.A. Khan, M. W. Grol
0 citations
Semantic Scholar

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