S. Strelkov

Most-cited papers

1. Characterization of human small heat shock protein HSPB1 α-crystallin domain localized mutants associated with hereditary motor neuron diseases

   S. Weeks, L. K. Muranova, M. Heirbaut, S. Beelen +2 more

   2018Scientific Reports35 citations Open access

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2. Molecular Interactions Driving Intermediate Filament Assembly

   Pieter-Jan Vermeire, G. Stalmans, A. V. Lilina, J. Fiala +3 more

   2021Cells34 citations Open access

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3. Lateral A11 type tetramerization in lamins.

   A. V. Lilina, A. Chernyatina, D. Guzenko, S. Strelkov

   2019Journal of Structural Biology30 citations Open access

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4. Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484

   M. Sillen, T. Miyata, D. Vaughan, S. Strelkov +1 more

   2021International Journal of Molecular Sciences29 citations Open access

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5. Specific sequences in the N-terminal domain of human small heat-shock protein HSPB6 dictate preferential hetero-oligomerization with the orthologue HSPB1

   M. Heirbaut, Frederik Lermyte, Esther M. Martin, S. Beelen +3 more

   2017Journal of Biological Chemistry28 citations Open access

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6. The Role of the Arginine in the Conserved N-Terminal Domain RLFDQxFG Motif of Human Small Heat Shock Proteins HspB1, HspB4, HspB5, HspB6, and HspB8

   Vladislav M. Shatov, S. Weeks, S. Strelkov, N. Gusev

   2018International Journal of Molecular Sciences23 citations Open access

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7. Mutations in HspB1 and hereditary neuropathies

   L. K. Muranova, M. V. Sudnitsyna, S. Strelkov, N. Gusev

   2020Cell stress & chaperones (Print)22 citations Open access

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8. The Heterooligomerization of Human Small Heat Shock Proteins Is Controlled by Conserved Motif Located in the N-Terminal Domain

   Vladislav M. Shatov, S. Strelkov, N. Gusev

   2020International Journal of Molecular Sciences19 citations Open access

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9. Molecular mechanism of two nanobodies that inhibit PAI-1 activity reveals a modulation at distinct stages of the PAI-1/plasminogen activator interaction

   M. Sillen, S. Weeks, Xiao-Hua Zhou, A. Komissarov +4 more

   2019Journal of Thrombosis and Haemostasis19 citations Open access

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10. Molecular structure of soluble vimentin tetramers

    Pieter-Jan Vermeire, A. V. Lilina, H. M. Hashim, Lada Dlabolová +6 more

    2023Scientific Reports18 citations Open access

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11. Concatenation of 14-3-3 with partner phosphoproteins as a tool to study their interaction

    K. Tugaeva, Daria I Kalacheva, R. Cooley, S. Strelkov +1 more

    2019Scientific Reports17 citations Open access

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12. Family-wide analysis of aminoacyl-sulfamoyl-3-deazaadenosine analogues as inhibitors of aminoacyl-tRNA synthetases.

    Bao-Le Zhang, S. De Graef, Manesh Nautiyal, L. Pang +6 more

    2018European journal of medicinal chemistry17 citations Open access

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13. 5-(Perylen-3-ylethynyl)uracil as an antiviral scaffold: Potent suppression of enveloped virus reproduction by 3-methyl derivatives in vitro.

    A. Chistov, S. Chumakov, Igor E. Mikhnovets, T. D. Nikitin +31 more

    2022Antiviral Research14 citations

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14. Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors.

    Dries De Ruysscher, L. Pang, Stijn Lenders, D. Cappoen +5 more

    2020European journal of medicinal chemistry14 citations Open access

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15. Organizational and pharmaceutical aspects of improving medicinal provision of children (on the example of St. Petersburg)

    I. Narkevich, O. Nemyatykh, D. M. Medvedeva, I. E. Smekhova +2 more

    2020JOURNAL of SIBERIAN MEDICAL SCIENCES13 citations Open access

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16. Discovery of a new Pro-Pro endopeptidase, PPEP-2, provides mechanistic insights into the differences in substrate specificity within the PPEP family

    O. Klychnikov, Tatiana M. Shamorkina, S. Weeks, H. V. van Leeuwen +6 more

    2018Journal of Biological Chemistry13 citations Open access

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17. Stability profile of vimentin rod domain

    A. V. Lilina, Simon Leekens, H. M. Hashim, Pieter-Jan Vermeire +2 more

    2022Protein Science12 citations Open access

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18. Structural Insights into the Mechanism of a Nanobody That Stabilizes PAI-1 and Modulates Its Activity

    M. Sillen, S. Weeks, S. Strelkov, P. Declerck

    2020International Journal of Molecular Sciences12 citations Open access

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19. Addressing the Molecular Mechanism of Longitudinal Lamin Assembly Using Chimeric Fusions

    G. Stalmans, A. V. Lilina, Pieter-Jan Vermeire, J. Fiala +2 more

    2020Cells12 citations Open access

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20. Structural insights into the binding of natural pyrimidine-based inhibitors of class II aminoacyl-tRNA synthetases.

    L. Pang, Manesh Nautiyal, S. De Graef, Bharat Gadakh +5 more

    2019ACS Chemical Biology11 citations Open access

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21. Effect of cataract-associated mutations in the N-terminal domain of αB-crystallin (HspB5).

    L. K. Muranova, S. Strelkov, N. Gusev

    2020Experimental Eye Research10 citations

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22. Acylated sulfonamide adenosines as potent inhibitors of the adenylate-forming enzyme superfamily.

    Dries De Ruysscher, L. Pang, S. De Graef, Manesh Nautiyal +5 more

    2019European journal of medicinal chemistry9 citations Open access

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23. Rational fragment-based design of compounds targeting the PWWP domain of the HRP family.

    Thibault Vantieghem, N. Aslam, E. M. Osipov, Muluembet Z. Akele +14 more

    2024European journal of medicinal chemistry8 citations Open access

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24. Phenyltriazole-functionalized sulfamate inhibitors targeting tyrosyl- or isoleucyl-tRNA synthetase.

    Dries De Ruysscher, L. Pang, Charles-Alexandre Mattelaer, Manesh Nautiyal +6 more

    2020Bioorganic & Medicinal Chemistry8 citations Open access

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25. Crystal structure of E. coli tyrRS in complex with 5'-O-(N-L-tyrosyl)sulfamoyl-cytidine

    S. De Graef, L. Pang, S. Strelkov, S. Weeks

    20198 citations

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26. Towards Novel 3-Aminopyrazinamide-Based Prolyl-tRNA Synthetase Inhibitors: In Silico Modelling, Thermal Shift Assay and Structural Studies

    L. Pang, S. Weeks, M. Juhás, S. Strelkov +2 more

    2021International Journal of Molecular Sciences7 citations Open access

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27. Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase.

    Bharat Gadakh, Gaston H. M. Vondenhoff, L. Pang, Manesh Nautiyal +4 more

    2020Bioorganic & Medicinal Chemistry7 citations Open access

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28. Partitioning of the initial catalytic steps of leucyl-tRNA synthetase is driven by an active site peptide-plane flip

    L. Pang, V. Zanki, S. Strelkov, A. van Aerschot +2 more

    2022Communications Biology6 citations Open access

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29. DDtrek: A PyMOL-Based Management System for 3D Structural Data Series

    E. M. Osipov, S. Strelkov

    2025ACS Omega5 citations Open access

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30. Crystal structure of Arabidopsis thaliana neutral invertase 2.

    Ł. Tarkowski, V. G. Tsirkone, E. M. Osipov, S. Beelen +4 more

    2020Acta Crystallographica Section F Structural Biology Communications5 citations Open access

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31. Discovery of Novel Druggable Sites on Zika Virus NS3 Helicase Using X-ray Crystallography-Based Fragment Screening

    Ali H. Munawar, S. Beelen, Ahmad Munawar, Eveline Lescrinier +1 more

    2018International Journal of Molecular Sciences5 citations Open access

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32. Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides

    L. Pang, Stijn Lenders, E. M. Osipov, S. Weeks +5 more

    2022International Journal of Molecular Sciences4 citations Open access

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33. Optimal data-driven parameterization of coiled coils

    D. Guzenko, S. Strelkov

    2018bioRxiv3 citations Open access

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34. Crystal engineering of the hepatoma-derived growth factor-related protein 2 PWWP domain towards crystallographic fragment screening.

    Thibault Vantieghem, E. M. Osipov, S. Beelen, S. Strelkov

    2025Acta Crystallographica Section F Structural Biology Communications2 citations Open access

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35. Trypanosoma brucei Seryl-tRNA Synthetase in Complex with 5'-O-(N-(L-seryl)-Sulfamoyl)uridine

    L. Pang, S. De Graef, S. Strelkov, S. Weeks

    20201 citations

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36. Synthesis and Biological Evaluation of 1,3-Dideazapurine-Like 7-Amino-5-Hydroxymethyl-Benzimidazole Ribonucleoside Analogues as Aminoacyl-tRNA Synthetase Inhibitors

    Bao-Le Zhang, L. Pang, Manesh Nautiyal, S. De Graef +6 more

    2020Molecules1 citations Open access

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37. Development and validation of a HPLC-method for the quantitative determination of coumarin in tonka beans

    V. Shurakova, E. S. Surbeeva, S. Strelkov, I. Terninko

    2025Drug development & registration0 citations Open access

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38. Author Correction: Molecular structure of soluble vimentin tetramers

    Pieter-Jan Vermeire, A. V. Lilina, H. M. Hashim, Lada Dlabolová +6 more

    2024Scientific Reports0 citations Open access

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39. Human Prolyl-tRNA Synthetase in Complex with L-proline and Compound 3c

    L. Pang, J. Zítko, S. Strelkov, S. Weeks

    20210 citations

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40. Human Prolyl-tRNA Synthetase in Complex with L-proline and Compound 3b

    L. Pang, J. Zítko, S. Strelkov, S. Weeks

    20210 citations

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41. Lamin A coil2 dimer stabilized by N-terminal capping

    A. V. Lilina, G. Stalmans, S. Strelkov

    20210 citations

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42. Human Prolyl-tRNA Synthetase in Complex with L-proline and Compound 4h

    L. Pang, J. Zítko, S. Strelkov, S. Weeks

    20210 citations

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43. Human Prolyl-tRNA Synthetase in Complex with L-proline and Compound 4j

    L. Pang, J. Zítko, S. Strelkov, S. Weeks

    20210 citations

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44. Oiled sludges of bottom sediments processing for rolling production of the metallurgical complex

    Yuliya Somova, T. Sviridova, S. Strelkov, V. S. Frolova +1 more

    2021PROCEEDINGS OF THE III INTERNATIONAL CONFERENCE ON ADVANCED TECHNOLOGIES IN MATERIALS SCIENCE, MECHANICAL AND AUTOMATION ENGINEERING: MIP: Engineering-III – 20210 citations

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45. Human Prolyl-tRNA Synthetase in Complex with L-proline

    L. Pang, J. Zítko, S. Strelkov, S. Weeks

    20210 citations

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46. Crystal Structure of Small Molecule Inhibitor TM5484 Bound to Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F)

    M. Sillen, S. Strelkov, P. Declerck

    20210 citations

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47. Crystal Structure of Small Molecule Inhibitor TM5484 Bound to Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab)

    M. Sillen, S. Strelkov, P. Declerck

    20210 citations

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48. Human Prolyl-tRNA Synthetase in Complex with L-proline and Compound 4d

    L. Pang, J. Zítko, S. Strelkov, S. Weeks

    20210 citations

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49. Neisseria gonorrhoeae Leucyl-tRNA Synthetase in Complex with Compound 11e

    L. Pang, S. Strelkov, S. Weeks

    20200 citations

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50. Crystal Structure of Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-stab) in Complex with Two Inhibitory Nanobodies (VHH-2g-42, VHH-2w-64)

    M. Sillen, S. Weeks, S. Strelkov, P. Declerck

    20200 citations

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