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Harish Shankaran · SciRah

Researcher profile · Semantic Scholar

Harish Shankaran

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Harish Shankaran — researcher profile on SciRah

h-index: 22
Works: 58
Citations: 1,636

Most-cited papers

Aspects of hydrodynamic shear regulating shear-induced platelet activation and self-association of von Willebrand factor in suspension.
Harish Shankaran, P. Alexandridis, S. Neelamegham
2003Blood255 citations Open access
Semantic Scholar
Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor
Harish Shankaran, D. Ippolito, W. Chrisler, H. Resat +3 more
2009Molecular Systems Biology252 citations Open access
Semantic Scholar
Cell Surface Receptors for Signal Transduction and Ligand Transport: A Design Principles Study
Harish Shankaran, H. Resat, H. Wiley
2007PLoS Comput. Biol.100 citations Open access
Semantic Scholar
Receptor downregulation and desensitization enhance the information processing ability of signalling receptors
Harish Shankaran, H. Wiley, H. Resat
2007BMC Systems Biology90 citations Open access
Semantic Scholar
Modeling the effects of HER/ErbB1-3 coexpression on receptor dimerization and biological response.
Harish Shankaran, H. Wiley, H. Resat
2006Biophysical Journal80 citations Open access
Semantic Scholar
Solution Structure of Human von Willebrand Factor Studied Using Small Angle Neutron Scattering*
Indrajeet Singh, Harish Shankaran, Mark E. Beauharnois, Zhihua Xiao +2 more
2006Journal of Biological Chemistry75 citations Open access
Semantic Scholar
Hydrodynamic forces applied on intercellular bonds, soluble molecules, and cell-surface receptors.
Harish Shankaran, S. Neelamegham
2004Biophysical Journal62 citations Open access
Semantic Scholar
Shear and Time-Dependent Changes in Mac-1, LFA-1, and ICAM-3 Binding Regulate Neutrophil Homotypic Adhesion1
S. Neelamegham, Andrew D. Taylor, Harish Shankaran, C. W. Smith +1 more
2000Journal of Immunology54 citations
Semantic Scholar
Investigating nephrotoxicity of polymyxin derivatives by mapping renal distribution using mass spectrometry imaging.
Anna Nilsson, R. Goodwin, J. Swales, R. Gallagher +8 more
2015Chemical Research in Toxicology51 citations
Semantic Scholar
Conserved host response to highly pathogenic avian influenza virus infection in human cell culture, mouse and macaque model systems
J. Mcdermott, Harish Shankaran, A. Eisfeld, Sarah E. Belisle +7 more
2011BMC Systems Biology49 citations Open access
Semantic Scholar
HER/ErbB receptor interactions and signaling patterns in human mammary epithelial cells
Yi Zhang, L. Opresko, Harish Shankaran, W. Chrisler +2 more
2009BMC Cell Biology45 citations Open access
Semantic Scholar
Oscillatory dynamics of the extracellular signal-regulated kinase pathway.
Harish Shankaran, H. Wiley
2010Current Opinion in Genetics and Development41 citations
Semantic Scholar
The Ability of Poloxamers to Inhibit Platelet Aggregation Depends on their Physicochemical Properties
Fariyal Ahmed, P. Alexandridis, Harish Shankaran, S. Neelamegham
2001Thrombosis and Haemostasis36 citations
Semantic Scholar
Physiologically-based pharmacokinetic model for Fentanyl in support of the development of Provisional Advisory Levels.
Harish Shankaran, F. Adeshina, Justin G. Teeguarden
2013Toxicology and Applied Pharmacology35 citations
Semantic Scholar
STRUCTURE OF THE EGF RECEPTOR TRANSACTIVATION CIRCUIT INTEGRATES MULTIPLE SIGNALS WITH CELL CONTEXT
Elizabeth J. Joslin, Harish Shankaran, L. Opresko, N. Bollinger +2 more
2010Molecular Biosystems32 citations Open access
Semantic Scholar
Nonlinear flow affects hydrodynamic forces and neutrophil adhesion rates in cone-plate viscometers.
Harish Shankaran, S. Neelamegham
2001Biophysical Journal28 citations Open access
Semantic Scholar
Biomechanics of P-selectin PSGL-1 bonds: shear threshold and integrin-independent cell adhesion.
Zhihua Xiao, H. Goldsmith, F. McIntosh, Harish Shankaran +1 more
2006Biophysical Journal27 citations Open access
Semantic Scholar
A Systems Toxicology Approach for the Prediction of Kidney Toxicity and Its Mechanisms In Vitro.
S. Ramm, Petar Todorov, V. Chandrasekaran, A. Dohlman +7 more
2019Toxicological Sciences26 citations Open access
Semantic Scholar
Effect of secondary flow on biological experiments in the cone‐plate viscometer: Methods for estimating collision frequency, wall shear stress and inter‐particle interactions in non‐linear flow
Harish Shankaran, S. Neelamegham
2001Biorheology26 citations
Semantic Scholar
Multiscale Mathematical Model of Drug-Induced Proximal Tubule Injury: Linking Urinary Biomarkers to Epithelial Cell Injury and Renal Dysfunction
Y. Gebremichael, James Lu, Harish Shankaran, G. Helmlinger +2 more
2018Toxicological Sciences24 citations
Semantic Scholar
Model-Based Analysis of HER Activation in Cells Co-Expressing EGFR, HER2 and HER3
Harish Shankaran, Yi Zhang, Yunbing Tan, H. Resat
2013PLoS Comput. Biol.24 citations Open access
Semantic Scholar
Basic fibroblast growth factor regulates persistent ERK oscillations in premalignant but not malignant JB6 cells.
T. J. Weber, Harish Shankaran, H. Wiley, L. Opresko +2 more
2010Journal of Investigative Dermatology24 citations Open access
Semantic Scholar
Quantifying the effects of co-expressing EGFR and HER2 on HER activation and trafficking.
Harish Shankaran, Yi Zhang, L. Opresko, H. Resat
2008Biochemical and Biophysical Research Communications - BBRC22 citations Open access
Semantic Scholar
Systems Pharmacology Model of Gastrointestinal Damage Predicts Species Differences and Optimizes Clinical Dosing Schedules
Harish Shankaran, Anna Cronin, J. Barnes, Pradeep Sharma +3 more
2017CPT: Pharmacometrics & Systems Pharmacology20 citations Open access
Semantic Scholar
Cell type‐dependent gene transcription profile in a three‐dimensional human skin tissue model exposed to low doses of ionizing radiation: Implications for medical exposures
Claere von Neubeck, Harish Shankaran, Norman J. Karin, Paula M. Kauer +6 more
2012Environmental and Molecular Mutagenesis20 citations
Semantic Scholar
Time-dependent behavioral data from zebrafish reveals novel signatures of chemical toxicity using point of departure analysis
Dennis G. Thomas, Harish Shankaran, L. Truong, Robert L. Tanguay +1 more
2018Computational Toxicology18 citations Open access
Semantic Scholar
Integrated experimental and model-based analysis reveals the spatial aspects of EGFR activation dynamics
Harish Shankaran, Yi Zhang, W. Chrisler, Jonathan A. Ewald +2 more
2012Molecular Biosystems17 citations Open access
Semantic Scholar
Integrated analysis reveals that STAT3 is central to the crosstalk between HER/ErbB receptor signaling pathways in human mammary epithelial cells
Chunhong Gong, Yi Zhang, Harish Shankaran, H. Resat
2014Molecular Biosystems16 citations Open access
Semantic Scholar
ERK Oscillation-Dependent Gene Expression Patterns and Deregulation by Stress Response
K. Waters, B. Cummings, Harish Shankaran, Natalie E. Scholpa +1 more
2014Chemical Research in Toxicology16 citations Open access
Semantic Scholar
Pharmacokinetic Properties of Humanized IgG1 and IgG4 Antibodies in Preclinical Species: Translational Evaluation
M. Tabrizi, Divas Neupane, Sophia E. Elie, Harish Shankaran +11 more
2019AAPS Journal12 citations
Semantic Scholar
Spatial Aspects in Biological System Simulations
H. Resat, Michelle N. Costa, Harish Shankaran
2011Methods in Enzymology12 citations Open access
Semantic Scholar
Smad Signaling Dynamics: Insights from a Parsimonious Model
Harish Shankaran, H. Wiley
2008Science Signaling10 citations
Semantic Scholar
Integrated experimental and computational approach to understand the effects of heavy ion radiation on skin homeostasis.
Claere von Neubeck, Harish Shankaran, Matthew Geniza, Paula M. Kauer +3 more
2013Integrative Biology8 citations
Semantic Scholar
System theoretical investigation of HER mediated signaling
Yi Zhang, Harish Shankaran, L. Opresko, H. Resat
2008IET Systems Biology7 citations Open access
Semantic Scholar
Inhibition of ERK oscillations by ionizing radiation and reactive oxygen species
Harish Shankaran, W. Chrisler, Ryan L. Sontag, T. J. Weber
2011Molecular Carcinogenesis6 citations
Semantic Scholar
Using measures of metabolic flux to align screening and clinical development: Avoiding pitfalls to enable translational studies.
S. Satapati, Daniel P. Downes, Daniel E. Metzger, Harish Shankaran +10 more
2021SLAS discovery : advancing life sciences R & D5 citations Open access
Semantic Scholar
Modeling Dynamic Regulatory Processes in Stroke
J. Mcdermott, K. Jarman, Ronald C. Taylor, Mary J. Lancaster +5 more
2012PLoS Comput. Biol.4 citations Open access
Semantic Scholar
Abstract 7133: Phenomics-enabled discovery and optimization of small-molecule RBM39 degraders as an alternative to CDK12 targeting in high-grade serous ovarian cancer (HGSOC)
Chase Neumann, Harish Shankaran, K. Nadella, Kelly Biette +18 more
2024Cancer Research2 citations
Semantic Scholar
Human Pharmacokinetics and Dose Projection of ETX2514/Sulbactam Combination for Use in the Treatment of Infections Caused by Acinetobacter baumannii
J. O'Donnell, Alita A. Miller, J. Mueller, A. TommasiRuben +2 more
20162 citations Open access
Semantic Scholar
Αlpha Beta (α/β) T cell Depleted Second HCT Is Effective for Impending Secondary Graft Failure after Reduced Intensity and Nonmyeloablative MSD HCT in Sickle Cell Disease
Mamatha Mandava, K. Snelling, Harish Shankaran, David A. Jacobsohn +2 more
2026Transplantation and Cellular Therapy1 citations
Semantic Scholar
A Surrogate Matrix-Based Approach Toward Multiplexed Quantitation of an sGC Stimulator and cGMP in Ocular Tissue and Plasma
Ken Lin, Pablo D. Cabral, Oscar Ekpenyong, Suzy El Bader +8 more
2020Toxicologic pathology (Print)1 citations
Semantic Scholar
Toxicokinetic Insights are Critical to Understanding Renal Toxicity of Novel Polymyxin Analog
Anshul Gupta, N. Keirstead, Harish Shankaran, R. Goodwin +8 more
20151 citations
Semantic Scholar
Abstract LB071: A phenomics platform combining imaging and artificial intelligence for rapid validation and advancement of novel oncology targets
J. Rudnick, K. Nadella, Chase Neumann, Shane D. Rowley +34 more
2023Cancer Research0 citations
Semantic Scholar
Concurrent quantitation of a small molecule sGC stimulator and cGMP in ocular tissue and plasma for target engagement studies after intravitreal administration. Applicability of a matrix-based approach.
Pablo D. Cabral, Ken Lin, Sherry X. Lu, Joana Galvao +12 more
20200 citations
Semantic Scholar
Application of Proof-of-Mechanism Biomarkers (POM) in Design and Development of Biologics Modalities
Glareh Azadi, G. Ayanoglu, Vaishnavi Ganti, Harish Shankaran +1 more
20180 citations
Semantic Scholar
Evaluation of Tumor Growth Inhibition in Preclinical Tumor Models: A Quantitative Approach
Shraddha Sadekar, I. Figueroa, Harish Shankaran
20180 citations
Semantic Scholar
Hemodynamic Consequences of Cisplatin‐Induced Acute Proximal Tubular Injury: A Mathematical Modeling Analysis
Y. Gebremichael, James Lu, Harish Shankaran, G. Helmlinger +2 more
2017The FASEB Journal0 citations Open access
Semantic Scholar
Multichannel microformulators for massively parallel machine learning and automated design of biological experiments
J. Wikswo, A. Kolli, Harish Shankaran, M. Wagoner +5 more
20170 citations
Semantic Scholar
Using Imaging Methods to Interrogate Radiation-Induced Cell Signaling
Harish Shankaran, T. J. Weber, Claere von Neubeck, M. Sowa
2012Radiation Research0 citations
Semantic Scholar
Structure of the EGF receptor transactivation circuit integrates with cell context
Elizabeth J. Joslin, Harish Shankaran, L. Opresko, N. Bollinger +2 more
20100 citations
Semantic Scholar

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Yi Zhang — researcher profile on SciRah

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