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M. Kane · SciRah

Researcher profile · Semantic Scholar

M. Kane

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M. Kane — researcher profile on SciRah

h-index: 34
Works: 47
Citations: 16K

Most-cited papers

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.
R. Fishel, M. Lescoe, M. Rao, N. Copeland +4 more
1993Cell2,757 citations
Semantic Scholar
Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer
C. Bronner, S. Baker, Paul T. Morrison, G. Warren +14 more
1994Nature2,187 citations
Semantic Scholar
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma.
J. G. Herman, A. Umar, K. Polyak, J. Graff +11 more
1998Proceedings of the National Academy of Sciences of the United States of America2,067 citations Open access
Semantic Scholar
Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines.
M. Kane, M. Loda, Gretchen M. Gaida, J. Lipman +4 more
1997Cancer Research1,582 citations
Semantic Scholar
Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.
G. Marsischky, N. Filosi, M. Kane, R. Kolodner
1996Genes & Development610 citations Open access
Semantic Scholar
Meiotic pachytene arrest in MLH1-deficient mice.
W. Edelmann, P. Cohen, M. Kane, Kirkland Lau +9 more
1996Cell606 citations Open access
Semantic Scholar
hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6.
S. Acharya, T. Wilson, S. Gradia, M. Kane +4 more
1996Proceedings of the National Academy of Sciences of the United States of America596 citations Open access
Semantic Scholar
Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma.
K. Ligon, E. Huillard, Shwetal Mehta, S. Kesari +9 more
2007Neuron520 citations Open access
Semantic Scholar
MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice.
B. Kneitz, P. Cohen, E. Avdievich, Li-Yin Zhu +6 more
2000Genes & Development475 citations Open access
Semantic Scholar
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2.
D. Tishkoff, A. Boerger, P. Bertrand, N. Filosi +3 more
1997Proceedings of the National Academy of Sciences of the United States of America412 citations Open access
Semantic Scholar
Mutation in the mismatch repair gene Msh6 causes cancer susceptibility.
W. Edelmann, Kan Yang, A. Umar, J. Heyer +13 more
1997Cell381 citations Open access
Semantic Scholar
Germ-line msh6 mutations in colorectal cancer families.
R. Kolodner, J. Tytell, J. Schmeits, M. Kane +10 more
1999Cancer Research357 citations
Semantic Scholar
Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility.
K. Wei, Alan B. Clark, Edmund Wong, M. Kane +11 more
2003Genes & Development351 citations Open access
Semantic Scholar
Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines.
J. Boyer, A. Umar, J. Risinger, J. Lipford +5 more
1995Cancer Research337 citations
Semantic Scholar
Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families
P. Tonin, B. Weber, K. Offit, F. Couch +24 more
1996Nature Medicine316 citations
Semantic Scholar
Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations.
Richard D. Kolodner, N. Hall, J. Lipford, M. Kane +9 more
1994Genomics287 citations
Semantic Scholar
Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression
M. Kucherlapati, Kan Yang, M. Kuraguchi, Jie Zhao +11 more
2002Proceedings of the National Academy of Sciences of the United States of America249 citations Open access
Semantic Scholar
Structure of the human MLH1 locus and analysis of a large hereditary nonpolyposis colorectal carcinoma kindred for mlh1 mutations.
Richard D. Kolodner, N. Hall, J. Lipford, M. Kane +6 more
1995Cancer Research227 citations
Semantic Scholar
Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas.
A. Børresen, R. Lothe, G. I. Meling, S. Lystad +5 more
1995Human Molecular Genetics175 citations
Semantic Scholar
Separated at birth? The functional and molecular divergence of OLIG1 and OLIG2
D. Meijer, M. Kane, Shwetal Mehta, Hong-Ye Liu +4 more
2012Nature Reviews Neuroscience165 citations Open access
Semantic Scholar
The central nervous system restricted transcription factor Olig2 opposes p53 responses to genotoxic damage in neural progenitors and malignant glioma
Shwetal Mehta, E. Huillard, S. Kesari, C. Maire +8 more
2011Cancer Cell164 citations Open access
Semantic Scholar
Identification of sequences in a yeast histone promoter involved in periodic transcription.
M. Osley, J. Gould, Sunyoung Kim, M. Kane +1 more
1986Cell162 citations
Semantic Scholar
Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice
Yu-Xun Wang, C. Putnam, M. Kane, Wei-Jia Zhang +7 more
2005Nature Genetics150 citations
Semantic Scholar
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
Yan-Hui Hu, A. Rolfs, Bhupinder Bhullar, T. V. Murthy +20 more
2007Genome Research130 citations Open access
Semantic Scholar
Phosphorylation state of Olig2 regulates proliferation of neural progenitors
Yu Sun, D. Meijer, J. Alberta, S. Mehta +10 more
2011Neuron113 citations Open access
Semantic Scholar
Mononucleotide microsatellite instability and germlineMSH6 mutation analysis in early onset colorectal cancer
L. Verma, M. Kane, C. Brassett, J. Schmeits +3 more
1999Journal of Medical Genetics110 citations Open access
Semantic Scholar
A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas
Yu Sun, J. Alberta, C. Pilarz, David Calligaris +18 more
2017Neuro-Oncology101 citations Open access
Semantic Scholar
Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA.
Eric Alani, Su-Man Lee, M. Kane, Jack D. Griffith +1 more
1997Journal of Molecular Biology99 citations Open access
Semantic Scholar
Cross-Repressive Interaction of the Olig2 and Nkx2.2 Transcription Factors in Developing Neural Tube Associated with Formation of a Specific Physical Complex
T. Sun, Hualing Dong, Li-Zi Wu, M. Kane +2 more
2003Journal of Neuroscience75 citations Open access
Semantic Scholar
A human compound heterozygote for two MLH1 missense mutations
P. Hackman, P. Tannergård, Salome Osei-Mensa, Jin-Dong Chen +5 more
1997Nature Genetics59 citations
Semantic Scholar
Identification and characterization of the Escherichia coli RecT protein, a protein encoded by the recE region that promotes renaturation of homologous single-stranded DNA
Sharynn D. Hall, M. Kane, R. Kolodner
199349 citations Open access
Semantic Scholar
Identification and Characterization of the Escherichia coli RecT Protein, a Protein Encoded by the recE Region That Promotes Renaturation of Homologous Single-Stranded DNA
Sharynn D. Hall, M. Kane, R. Kolodner
1993Journal of Bacteriology48 citations Open access
Semantic Scholar
Mutational analysis of the hMSH2 gene reveals a three base pair deletion in a family predisposed to colorectal cancer development.
J. Mary, T. Bishop, Richard D. Kolodner, J. Lipford +6 more
1994Human Molecular Genetics41 citations
Semantic Scholar
Identification and characterization of Saccharomyces cerevisiae EXO 1 , a gene encoding an exonuclease that interacts with MSH 2
D. Tishkoff, A. Boerger, P. Bertrand, N. Filosi +3 more
199734 citations
Semantic Scholar
Low frequency of hMSH2 mutations in Swedish HNPCC families
S. Wahlberg, M. Nystrom-Lahti, M. Kane, Richard D. Kolodner +2 more
1997International Journal of Cancer26 citations Open access
Semantic Scholar
An Amino Terminal Phosphorylation Motif Regulates Intranuclear Compartmentalization of Olig2 in Neural Progenitor Cells
D. Meijer, Yu Sun, T. Liu, M. Kane +8 more
2014Journal of Neuroscience25 citations Open access
Semantic Scholar
Human mismatch repair genes and their association with hereditary non-polyposis colon cancer.
Richard D. Kolodner, N. Hall, J. Lipford, M. Kane +28 more
1994Cold Spring Harbor Symposia on Quantitative Biology23 citations
Semantic Scholar
Structure of the Human MLH 1 Locus and Analysis of a Large Hereditary Nonpolyposis Colorectal Carcinoma Kindred for mihi Mutations '
R. Kolodner, N. Hall, J. Lipford, M. Kane +7 more
200617 citations
Semantic Scholar
Germ-line msh 6 Mutations in Colorectal Cancer Families 1
R. Kolodner, J. Tytell, J. Schmeits, M. Kane +10 more
19998 citations
Semantic Scholar
Advances in Brief Methylation of the hMLHJ Promoter Correlates with Lack of Expression of hMLH 1 in Sporadic Colon Tumors and Mismatch Repair-defective Human Tumor Cell Lines '
M. Kane, M. Loda, Gretchen M. Gaida, J. Lipman +5 more
20067 citations
Semantic Scholar
Repair-defective Human Tumor Cell Lines Expression of hMLH 1 in Sporadic Colon Tumors and Mismatch Promoter Correlates with Lack of hMLH 1 Methylation of the Updated
M. Kane, M. Loda, Gretchen M. Gaida, J. Lipman +3 more
20062 citations
Semantic Scholar
Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2 (canceryhereditary nonpolyposis colorectal carcinomaymutagenesisymutS)
D. Tishkoff, L. Boerger, P. Bertrand, N. Filosi +4 more
19972 citations
Semantic Scholar
LG-47TYPE II RAF INHIBITORS INHIBIT BRAF MUTATIONS AND TRUNCATED FUSIONS IN PEDIATRIC LOW-GRADE GLIOMAS
M. Kieran, Yu Sun, C. Pilarz, David Calligaris +22 more
20160 citations Open access
Semantic Scholar
AnAminoTerminalPhosphorylationMotifRegulates IntranuclearCompartmentalizationofOlig2inNeural ProgenitorCells
M. Kane, C. Stiles
20140 citations
Semantic Scholar
ID4 function Antagonizes Olig1 and Olig2 to suppress aggressive gliomagenesis
E. Huillard, J. Alberta, J. Phillips, Amélie Griveau +8 more
20130 citations
Semantic Scholar
Saccharomyces cerevisiaeprotein-encoding clones for Approaching a complete repository of sequence-verified data
J. L. Williamson, A. Simpson, M. Bulyk, E. Harlow +20 more
20070 citations
Semantic Scholar
mlh 1 Mutations Hereditary Nonpolyposis Colorectal Carcinoma Kindred for Locus and Analysis of a Large MLH 1 Structure of the Human Updated
R. Kolodner, N. Hall, J. Lipford, M. Kane +7 more
20060 citations
Semantic Scholar

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