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Yosuke Nagai · SciRah

Researcher profile · Semantic Scholar

Yosuke Nagai

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Yosuke Nagai — researcher profile on SciRah

h-index: 12
Works: 46
Citations: 742

Most-cited papers

Unraveling the Role of Inflammation in the Pathogenesis of Diabetic Kidney Disease
Keiichiro Matoba, Yusuke Takeda, Yosuke Nagai, D. Kawanami +2 more
2019International Journal of Molecular Sciences193 citations Open access
Semantic Scholar
SGLT2 Inhibitors as a Therapeutic Option for Diabetic Nephropathy
D. Kawanami, Keiichiro Matoba, Yusuke Takeda, Yosuke Nagai +4 more
2017International Journal of Molecular Sciences151 citations Open access
Semantic Scholar
Endothelial Dysfunction in Diabetes
Yusuke Takeda, Keiichiro Matoba, Kensuke Sekiguchi, Yosuke Nagai +3 more
2020Biomedicines62 citations Open access
Semantic Scholar
Targeting Redox Imbalance as an Approach for Diabetic Kidney Disease
Keiichiro Matoba, Yusuke Takeda, Yosuke Nagai, T. Yokota +2 more
2020Biomedicines55 citations Open access
Semantic Scholar
ROCK2 Regulates Monocyte Migration and Cell to Cell Adhesion in Vascular Endothelial Cells
Yusuke Takeda, Keiichiro Matoba, D. Kawanami, Yosuke Nagai +5 more
2019International Journal of Molecular Sciences52 citations Open access
Semantic Scholar
ROCK2 regulates TGF-β-induced expression of CTGF and profibrotic genes via NF-κB and cytoskeleton dynamics in the mesangial cells.
Yosuke Nagai, Keiichiro Matoba, D. Kawanami, Yusuke Takeda +6 more
2019AJP - Renal Physiology50 citations Open access
Semantic Scholar
Rho-Kinase Blockade Attenuates Podocyte Apoptosis by Inhibiting the Notch Signaling Pathway in Diabetic Nephropathy
Keiichiro Matoba, D. Kawanami, Yosuke Nagai, Yusuke Takeda +5 more
2017International Journal of Molecular Sciences37 citations Open access
Semantic Scholar
The Physiology, Pathology, and Therapeutic Interventions for ROCK Isoforms in Diabetic Kidney Disease
Keiichiro Matoba, Yusuke Takeda, Yosuke Nagai, Kensuke Sekiguchi +3 more
2020Frontiers in Pharmacology29 citations Open access
Semantic Scholar
Rho-associated, coiled-coil-containing protein kinase 1 regulates development of diabetic kidney disease via modulation of fatty acid metabolism.
Yosuke Nagai, Keiichiro Matoba, Yusuke Takeda, H. Yako +8 more
2022Kidney International22 citations Open access
Semantic Scholar
ROCK2-induced metabolic rewiring in diabetic podocytopathy
Keiichiro Matoba, Yusuke Takeda, Yosuke Nagai, Kensuke Sekiguchi +10 more
2022Communications Biology21 citations Open access
Semantic Scholar
Renal ROCK Activation and Its Pharmacological Inhibition in Patients With Diabetes
Keiichiro Matoba, Kensuke Sekiguchi, Yosuke Nagai, Yusuke Takeda +4 more
2021Frontiers in Pharmacology18 citations Open access
Semantic Scholar
Rho-kinase inhibitor restores glomerular fatty acid metabolism in diabetic kidney disease.
Yosuke Nagai, Keiichiro Matoba, H. Yako, Shinji Ohashi +6 more
2023Biochemical and Biophysical Research Communications - BBRC13 citations
Semantic Scholar
ROCK Inhibition May Stop Diabetic Kidney Disease
Keiichiro Matoba, Yusuke Takeda, Yosuke Nagai, Yasushi Kanazawa +4 more
2020JMA Journal11 citations Open access
Semantic Scholar
Deletion of podocyte Rho-associated, coiled-coil-containing protein kinase 2 protects mice from focal segmental glomerulosclerosis
Keiichiro Matoba, Yosuke Nagai, Kensuke Sekiguchi, Shinji Ohashi +7 more
2024Communications Biology6 citations Open access
Semantic Scholar
505-P: ROCK2 Regulates TGF-Beta-Induced Expression of CTGF and Profibrotic Genes via NF-kappa B and Cytoskeleton Dynamics in the Mesangial Cells
Yosuke Nagai, D. Kawanami, Keiichiro Matoba, Yusuke Takeda +1 more
2019Diabetes6 citations
Semantic Scholar
ROCK signaling at the crossroads of redox stress, mitochondrial dynamics, and metabolic disease
Yosuke Nagai, Keiichiro Matoba, R. Nishimura
2026Redox Biology5 citations Open access
Semantic Scholar
Development of ultrafast camera-based imaging of single fluorescent molecules and live-cell PALM
T. Fujiwara, Shinji Takeuchi, Ziya Kalay, Yosuke Nagai +6 more
2021bioRxiv3 citations Open access
Semantic Scholar
Rho-associated, coiled-coil-containing protein kinase 2 regulates expression of mineralocorticoid receptor to mediate sodium reabsorption in mice.
Kensuke Sekiguchi, Keiichiro Matoba, Yosuke Nagai, Satoru Nagao +8 more
2024Biochemical and Biophysical Research Communications - BBRC2 citations
Semantic Scholar
Focal adhesion membrane is dotted with protein islands and partitioned for molecular hop diffusion
T. Fujiwara, Shinji Takeuchi, Ziya Kalay, Yosuke Nagai +8 more
2021bioRxiv2 citations Open access
Semantic Scholar
426-P: ROCK2 Regulates Monocytic Migration and Cell-to-Cell Adhesion in Vascular Endothelial Cells
Yusuke Takeda, Keiichiro Matoba, D. Kawanami, Yosuke Nagai +1 more
2019Diabetes1 citations
Semantic Scholar
Rho-Kinase Induces CTGF Expression through Actin Dynamics in Mesangial Cells
Yosuke Nagai, D. Kawanami, Keiichiro Matoba, Yusuke Takeda +5 more
2018Diabetes1 citations
Semantic Scholar
J-036 Life Activity Recording Support Using an Interactive Character Agent for Elderly
Yosuke Nagai, Masayuki Hayashi, Masayuki Kanbara, N. Hagita
20141 citations
Semantic Scholar
HFpEF as a diabetic complication: the central role of microvascular dysfunction
Yosuke Nagai, Keiichiro Matoba, R. Nishimura
2026Discover Endocrinology and Metabolism0 citations Open access
Semantic Scholar
1384-P: Distinct Role of ROCK1 in the Regulation of Fatty Acid Energy Metabolism in Kidney Tubules
Satoru Nagao, Keiichiro Matoba, Shinji Ohashi, Yosuke Nagai +1 more
2026Diabetes0 citations
Semantic Scholar
384-P: The Role of ROCK Isoform in the Impairment of Tubular Fatty Acid Metabolism
Satoru Nagao, Keiichiro Matoba, Shinji Ohashi, Kensuke Sekiguchi +3 more
2025Diabetes0 citations
Semantic Scholar
237-OR: Adipocyte–Endothelial Cell Cross Talk in Adipose Tissue—The Impact of Rho-Associated, Coiled-Coil–Containing Protein Kinase 2 on Insulin Resistance
Shinji Ohashi, Keiichiro Matoba, Satoru Nagao, Kensuke Sekiguchi +3 more
2025Diabetes0 citations
Semantic Scholar
Atypical periprosthetic femoral fractures around cemented stems: Radiographic features and clinical implications from a multicenter study.
Ken Tashiro, Tomonori Baba, Hiroshi Fujita, Hiroaki Iwase +11 more
2025Bone0 citations Open access
Semantic Scholar
Abstract Wed099: Endothelial KLF4 regulates heart failure with preserved ejection fraction
Tapatee Das, Yosuke Nagai, Xudong Liao, Mukesh K. Jain
2025Circulation Research0 citations
Semantic Scholar
111-OR: Vascular Endothelium-Specific ROCK2 Deficiency Inhibits the Progression of Obesity via Adipocyte Browning
Shinji Ohashi, Keiichiro Matoba, Kensuke Sekiguchi, Etsuko Mitsuyoshi +2 more
2024Diabetes0 citations
Semantic Scholar
391-P: Targeted Deletion of Rho-Associated Coiled-Coil–Containing Protein Kinase 2 in Kidney Tubules Suppresses Expression and Function of Mineralocorticoid Receptor in Mice
Kensuke Sekiguchi, Keiichiro Matoba, Shinji Ohashi, Etsuko Mitsuyoshi +2 more
2024Diabetes0 citations
Semantic Scholar
405-P: ROCK2 Activation and Its Role in Folic Acid–Induced Murine Model of Nephropathy
Kensuke Sekiguchi, Keiichiro Matoba, Shinji Ohashi, Etsuko Mitsuyoshi +3 more
2023Diabetes0 citations
Semantic Scholar
Unexpected Acute Hyperglycemia Following Pre-Surgical Discontinuation of SGLT2 Inhibitors in a Type 1 Diabetic Patient
Y. Tsujimoto, Yosuke Nagai, R. Nishimura
2023The American journal of case reports0 citations Open access
Semantic Scholar
6-OR: Vascular Endothelial ROCK2 Deficiency Promotes Browning and Burning of White Adipose Tissue
Yusuke Takeda, Keiichiro Matoba, Rikako Ukichi, Kensuke Sekiguchi +4 more
2022Diabetes0 citations
Semantic Scholar
388-P: Renal ROCK2 Activity in Folic Acid-Induced Nephropathy
Kensuke Sekiguchi, Keiichiro Matoba, Rikako Ukichi, Yosuke Nagai +4 more
2022Diabetes0 citations
Semantic Scholar
386-P: ROCK1 Regulation of AMPK in the Development of Diabetic Nephropathy
Yosuke Nagai, Keiichiro Matoba, Kensuke Sekiguchi, Yusuke Takeda +4 more
2022Diabetes0 citations
Semantic Scholar
392-P: ROCK2-Mediated Podocyte Dysfunction in Diabetic Nephropathy
Keiichiro Matoba, Yusuke Takeda, Tomoyo Akamine, Yosuke Nagai +4 more
2021Diabetes0 citations
Semantic Scholar
117-OR: Inhibition of Endothelial ROCK2 Induces Fat Browning and Improves Metabolic Dysfunction
Yusuke Takeda, Keiichiro Matoba, Yosuke Nagai, Rikako Ukichi +5 more
2021Diabetes0 citations
Semantic Scholar
389-P: Pathological Significance of Renal Tubular ROCK2 in Chronic Kidney Disease
Kensuke Sekiguchi, Keiichiro Matoba, Rikako Ukichi, Yosuke Nagai +5 more
2021Diabetes0 citations
Semantic Scholar
394-P: ROCK1/AMPK Axis Regulates the Development of Diabetic Kidney Disease via Modulation of Fatty Acid Metabolism
Yosuke Nagai, Keiichiro Matoba, Kensuke Sekiguchi, Rikako Ukichi +5 more
2021Diabetes0 citations
Semantic Scholar
1692-P: Ablation of Endothelial ROCK2 Promotes Fat Browning and Improves Metabolic Dysfunction
Yusuke Takeda, Keiichiro Matoba, D. Kawanami, Yosuke Nagai +2 more
20200 citations
Semantic Scholar
469-P: ROCK1/AMPK Axis Regulates the Development of Diabetic Kidney Disease via Modulation of Fatty Acid Metabolism
Yosuke Nagai, Keiichiro Matoba, Yusuke Takeda, Tomoyo Akamine +3 more
20200 citations
Semantic Scholar
481-P: Renal Distribution and Expression Analysis of ROCK Isoforms in Diabetic Kidney Disease
Keiichiro Matoba, Yusuke Takeda, Yosuke Nagai, Tomoyo Akamine +4 more
20200 citations
Semantic Scholar
501-P: ROCK2 Activation Accelerates Podocyte Injury in Diabetic Kidney Disease
Keiichiro Matoba, D. Kawanami, Yusuke Takeda, Yosuke Nagai +1 more
2019Diabetes0 citations
Semantic Scholar
ROCK2 Regulates the Expression of Cell Adhesion Molecules and Cell-to-Cell Adhesion in Vascular Endothelial Cells
Yusuke Takeda, Keiichiro Matoba, D. Kawanami, Yosuke Nagai +5 more
2018Diabetes0 citations
Semantic Scholar
Life Activity Recording Method Using Interactive Character Agent for the Elderly
Yosuke Nagai, Masayuki Hayashi, Masayuki Kanbara, Hagita Norihiro
20140 citations
Semantic Scholar
Social Viewing System of Television Increasing Opportunity of Communication for Elderly
Masayuki Hayashi, Yosuke Nagai, Masayuki Kanbara, Hagita Norihiro
20140 citations
Semantic Scholar

Frequent co-authors

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Keiichiro Matoba×38
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Keiichiro Matoba — researcher profile on SciRah
R. Nishimura×29
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R. Nishimura — researcher profile on SciRah
Yusuke Takeda×28
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Yusuke Takeda — researcher profile on SciRah
K. Utsunomiya×28
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K. Utsunomiya — researcher profile on SciRah

×20

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D. Kawanami — researcher profile on SciRah

Kensuke Sekiguchi×19

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Kensuke Sekiguchi — researcher profile on SciRah

Yasushi Kanazawa×17

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Yasushi Kanazawa — researcher profile on SciRah

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T. Yokota — researcher profile on SciRah

Tomoyo Akamine×13

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Tomoyo Akamine — researcher profile on SciRah

Shinji Ohashi×9

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Shinji Ohashi — researcher profile on SciRah

Etsuko Mitsuyoshi×8

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Etsuko Mitsuyoshi — researcher profile on SciRah

Rikako Ukichi×7

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Rikako Ukichi — researcher profile on SciRah