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Shivashankar Khanapur · SciRah

Researcher profile · Semantic Scholar

Shivashankar Khanapur

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Shivashankar Khanapur — researcher profile on SciRah

h-index: 13
Works: 42
Citations: 415

Most-cited papers

Potential Therapeutic Applications of Adenosine A2A Receptor Ligands and Opportunities for A2A Receptor Imaging
A. van Waarde, R. Dierckx, Xiaoyun Zhou, Shivashankar Khanapur +5 more
2018Medicinal research reviews (Print)36 citations Open access
Semantic Scholar
Synthesis and preclinical evaluation of 2-(2-furanyl)-7-[2-[4-[4-(2-[11C]methoxyethoxy)phenyl]-1-piperazinyl]ethyl]7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidine-5-amine ([11C]Preladenant) as a PET tracer for the imaging of cerebral adenosine A2A receptors.
Xiaoyun Zhou, Shivashankar Khanapur, A. Huizing, R. Zijlma +5 more
2014Journal of Medicinal Chemistry31 citations
Semantic Scholar
Imaging adipose tissue browning using the TSPO-18kDa tracer [18F]FEPPA
S. Hartimath, Shivashankar Khanapur, R. Boominathan, Lingfan Jiang +5 more
2019Molecular Metabolism29 citations Open access
Semantic Scholar
Development of [18F]-labeled pyrazolo[4,3-e]-1,2,4- triazolo[1,5-c]pyrimidine (SCH442416) analogs for the imaging of cerebral adenosine A2A receptors with positron emission tomography.
Shivashankar Khanapur, S. Paul, Anup D. Shah, Suresh Vatakuti +7 more
2014Journal of Medicinal Chemistry28 citations
Semantic Scholar
Granzyme B PET Imaging of Combined Chemotherapy and Immune Checkpoint Inhibitor Therapy in Colon Cancer
J. Goggi, S. Hartimath, Tan-Yun Xuan, Shivashankar Khanapur +13 more
2021Molecular Imaging and Biology27 citations Open access
Semantic Scholar
Small-Animal PET Study of Adenosine A1 Receptors in Rat Brain: Blocking Receptors and Raising Extracellular Adenosine
S. Paul, Shivashankar Khanapur, A. Rybczynska, C. Kwizera +6 more
2011Journal of Nuclear Medicine27 citations Open access
Semantic Scholar
Fluorine-18 Labeling of Difluoromethyl and Trifluoromethyl Groups via Monoselective C-F Bond Activation.
Shivashankar Khanapur, Kenneth Lye, D. Mandal, Jie-Wee Xin +2 more
2022Angewandte Chemie24 citations
Semantic Scholar
Adenosine A(2A) receptor antagonists as Positron Emission Tomography (PET) tracers.
Shivashankar Khanapur, A. van Waarde, K. Ishiwata, K. Leenders +2 more
2013Current Medicinal Chemistry21 citations
Semantic Scholar
Examining Immunotherapy Response Using Multiple Radiotracers
J. Goggi, S. Hartimath, Y. Hwang, Yun-Xuan Tan +14 more
2020Molecular Imaging and Biology19 citations
Semantic Scholar
Use of 11C-MPDX and PET to Study Adenosine A1 Receptor Occupancy by Nonradioactive Agonists and Antagonists
S. Paul, Shivashankar Khanapur, J. Sijbesma, K. Ishiwata +4 more
2014Journal of Nuclear Medicine18 citations Open access
Semantic Scholar
Radiation Dosimetry of a Novel Adenosine A2A Receptor Radioligand [11C]Preladenant Based on PET/CT Imaging and Ex Vivo Biodistribution in Rats
Xiaoyun Zhou, P. Elsinga, Shivashankar Khanapur, R. Dierckx +2 more
2016Molecular Imaging and Biology17 citations Open access
Semantic Scholar
In vivo evaluation of [11C]preladenant positron emission tomography for quantification of adenosine A2A receptors in the rat brain
Xiaoyun Zhou, Shivashankar Khanapur, J. D. de Jong, A. Willemsen +3 more
2017Journal of Cerebral Blood Flow and Metabolism16 citations Open access
Semantic Scholar
Preclinical Evaluation and Quantification of 18F-Fluoroethyl and 18F-Fluoropropyl Analogs of SCH442416 as Radioligands for PET Imaging of the Adenosine A2A Receptor in Rat Brain
Shivashankar Khanapur, A. van Waarde, R. Dierckx, P. Elsinga +1 more
2017Journal of Nuclear Medicine16 citations Open access
Semantic Scholar
Imaging Kv1.3 Expressing Memory T Cells as a Marker of Immunotherapy Response
J. Goggi, Shivashankar Khanapur, Boominathan Ramasamy, S. Hartimath +10 more
2022Cancers13 citations Open access
Semantic Scholar
Reaching out for Sensitive Evaluation of the Mu Opioid Receptor in Vivo: Positron Emission Tomography Imaging of the Agonist [11C]AH7921.
W. Rafique, Shivashankar Khanapur, Mona M Spilhaug, P. Riss
2017ACS Chemical Neuroscience13 citations Open access
Semantic Scholar
Granzyme B PET Imaging in Response to In Situ Vaccine Therapy Combined with αPD1 in a Murine Colon Cancer Model
S. Hartimath, Boominathan Ramasamy, Yun-Xuan Tan, Jun-Rong Tang +5 more
2022Pharmaceutics12 citations Open access
Semantic Scholar
Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson’s disease
J. Goggi, Lifeng Qiu, Mei-Chih Liao, Shivashankar Khanapur +20 more
2020Stem cell research & therapeutics11 citations Open access
Semantic Scholar
Longitudinal [18F]FB-IL-2 PET Imaging to Assess the Immunopathogenicity of O'nyong-nyong Virus Infection
Y. Chan, Teck-Hui Teo, Anthony Torres‐Ruesta, S. Hartimath +12 more
2020Frontiers in Immunology11 citations Open access
Semantic Scholar
Cerebral adenosine A1 receptors are upregulated in rodent encephalitis
S. Paul, Shivashankar Khanapur, W. Boersma, J. Sijbesma +6 more
2014NeuroImage10 citations
Semantic Scholar
Arginine-Selective Bioconjugation Reagent for Effective 18F-labeling of Native Proteins
P. Sadasivam, Shivashankar Khanapur, S. Hartimath, Boominathan Ramasamy +7 more
2024Journal of Medicinal Chemistry6 citations Open access
Semantic Scholar
An Improved Synthesis of N-(4-[18F]Fluorobenzoyl)-Interleukin-2 for the Preclinical PET Imaging of Tumour-Infiltrating T-cells in CT26 and MC38 Colon Cancer Models
Shivashankar Khanapur, F. Yong, S. Hartimath, Lingfan Jiang +5 more
2021Molecules6 citations Open access
Semantic Scholar
Imaging Adipose Tissue Browning using Mitochondrial Complex-I Tracer [18F]BCPP-EF
J. Goggi, S. Hartimath, Shivashankar Khanapur, Boominathan Ramasamy +5 more
2022Contrast Media & Molecular Imaging5 citations Open access
Semantic Scholar
Imaging Memory T-Cells Stratifies Response to Adjuvant Metformin Combined with αPD-1 Therapy
J. Goggi, S. Hartimath, Shivashankar Khanapur, Boominathan Ramasamy +5 more
2022International Journal of Molecular Sciences4 citations Open access
Semantic Scholar
Synthesis and Characterization in Rodent Brain of the Subtype-Selective NR2B NMDA Receptor Ligand [11C]Ro04-5595 as a Potential Radiotracer for Positron Emission Tomography
J. Jakobsson, E. Gourni, Shivashankar Khanapur, Beatriz Brito +1 more
2019ACS Omega4 citations Open access
Semantic Scholar
Novel [18F]FPG-interleukin-2 conjugate for monitoring immune checkpoint therapy with positron emission tomography.
P. Sadasivam, S. Hartimath, Shivashankar Khanapur, Boominathan Ramasamy +6 more
2024Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie3 citations Open access
Semantic Scholar
Imaging Effector Memory T-Cells Predicts Response to PD1-Chemotherapy Combinations in Colon Cancer
J. Goggi, Shivashankar Khanapur, S. Hartimath, Boominathan Ramasamy +5 more
2022Biomedicines3 citations Open access
Semantic Scholar
PET Imaging of Adenosine A1 Receptor Occupancy
S. Paul, Shivashankar Khanapur, P. Elsinga, K. Ishiwata +3 more
2014Journal of Nuclear Medicine3 citations Open access
Semantic Scholar
Mitochondrial complex I as a diagnostic and therapeutic target in a mouse model of tauopathy
J. Wong, A. S. Vincent, Shivashankar Khanapur, Tang-Jun Rong +7 more
2023bioRxiv1 citations Open access
Semantic Scholar
Use of 11 C-MPDX and PET to Study Adenosine A 1 Receptor Occupancy by Nonradioactive Agonists and Antagonists
S. Paul, Shivashankar Khanapur, J. Sijbesma, K. Ishiwata +4 more
20141 citations
Semantic Scholar
Dynamic [18F]Fluoroleucine PET Detects Impaired Cardiac Leucine Uptake Before Hypertensive Left Ventricular Hypertrophy Develops
William Terrell, Jie Li, Damodara N. Kommi, Megan E. Burt +4 more
2026bioRxiv0 citations Open access
Semantic Scholar
Dynamic [18F]Fluoroleucine PET Detects Impaired Cardiac Leucine Uptake Before Hypertensive Left Ventricular Hypertrophy Develops
William Terrell, Jie Li, Damodara N. Kommi, Megan E. Burt +4 more
2026Research Square0 citations Open access
Semantic Scholar
Radiolabeling molecular biomarkers of invasive pituitary adenomas: a narrative review
C. Marche, J. Knop, Shivashankar Khanapur, Eric Suero Molina +3 more
2025Pituitary0 citations
Semantic Scholar
Facile Automated Radiosynthesis of an Arginine Selective Bioconjugation Reagent 4‑[18F]Fluorophenylglyoxal for Developing Protein-Based PET Molecular Probes
P. Sadasivam, Shivashankar Khanapur, S. Hartimath, Boominathan Ramasamy +6 more
2025ACS Omega0 citations Open access
Semantic Scholar
A Novel Prosthetic group, 4-[18F]Fluorophenylglyoxal for Protein Conjugation
P. Sadasivam, Shivashankar Khanapur, S. Hartimath, Boominathan Ramasamy +5 more
2023Nuclear Medicine and Biology0 citations
Semantic Scholar
Dopamine transporter neuroimaging accurately assesses the maturation of dopamine neurons in a preclinical model of Parkinson’s disease
J. Goggi, Lifeng Qiu, Mei-Chih Liao, Shivashankar Khanapur +20 more
2020Stem cell research & therapeutics0 citations Open access
Semantic Scholar
University of Groningen Radiation Dosimetry of a Novel Adenosine A(2A) Receptor Radioligand [C-11]Preladenant Based on PET/CT Imaging and Ex Vivo Biodistribution in Rats
P. Elsinga, Shivashankar Khanapur, R. Dierckx, E. D. de Vries +1 more
20170 citations
Semantic Scholar
In vivo evaluation of [11C] preladenant PET for quantification of adenosine A2A receptors in the rat brain
Shivashankar Khanapur, J. D. de Jong, A. Willemsen, R. Dierckx +2 more
20170 citations
Semantic Scholar
PET imaging to measure therapy-related occupancy and disease-induced changes of expression of adenosine A1 receptors
S. Paul, P. Elsinga, Shivashankar Khanapur, K. Ishiwata +3 more
20140 citations
Semantic Scholar
Development and Preclinical Evaluation of a Novel F-18 Labeled SCH442416 Analog for Imaging Adenosine A2A Receptors
Shivashankar Khanapur, S. Paul, A. Shah, G. Luurtsema +5 more
20130 citations
Semantic Scholar
MicroPET studies of antagonist/agonist competition with ligand binding to adenosine A1 receptors in rat brain
S. Paul, Shivashankar Khanapur, M. Khayum, J. Sijbesma +5 more
20130 citations
Semantic Scholar
Encephalitis changes binding of the adenosine A1 receptor antagonist C-11-MPDX in rat pons
S. Paul, Shivashankar Khanapur, M. Khayum, J. Sijbesma +6 more
20120 citations
Semantic Scholar
Visualization of adenosine A1 receptors in rat brain, using 11C-MPDX and microPET : effect of raised levels of extracellular adenosine
van Aren Waarde, de Anna Bruyn-Rybczynska, S. Paul, Shivashankar Khanapur +4 more
20100 citations
Semantic Scholar

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