W. Ruan

Most-cited papers

Actin, a reliable marker of internal control?
W. Ruan, M. Lai
2007Clinica chimica acta; international journal of clinical chemistry214 citations
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IGFBP7 plays a potential tumor suppressor role in colorectal carcinogenesis
W. Ruan, E. Xu, Fang-Ying Xu, Yu Ma +9 more
2007Cancer Biology & Therapy113 citations Open access
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Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies
Si-Hua Peng, Bin Lu, W. Ruan, Yi-Min Zhu +2 more
2011Breast Cancer Research and Treatment105 citations
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Insulin-like growth factor binding protein: a possible marker for the metabolic syndrome?
W. Ruan, M. Lai
2010Acta Diabetologica92 citations
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The SH2/SH3 adaptor protein dock interacts with the Ste20-like kinase misshapen in controlling growth cone motility.
W. Ruan, Peng Pang, Yong Rao
1999Neuron78 citations Open access
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Methylation patterns of IGFBP7 in colon cancer cell lines are associated with levels of gene expression
Jie Lin, M. Lai, Qiong Huang, Yu Ma +2 more
2007Journal of Pathology66 citations
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LRRK2 localizes to endosomes and interacts with clathrin‐light chains to limit Rac1 activation
A. Schreij, M. Chaineau, W. Ruan, Susan S. Lin +3 more
2014EMBO Reports65 citations Open access
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brakeless is required for photoreceptor growth-cone targeting in Drosophila.
Yong Rao, Peng Pang, W. Ruan, D. Gunning +1 more
2000Proceedings of the National Academy of Sciences of the United States of America49 citations Open access
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A novel juxtamembrane domain in tumor necrosis factor receptor superfamily molecules activates Rac1 and controls neurite growth.
W. Ruan, Christopher T. Lee, J. Desbarats
2008Molecular Biology of the Cell46 citations Open access
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The Ste20-like kinase misshapen functions together with Bicaudal-D and dynein in driving nuclear migration in the developing drosophila eye.
T. Houalla, Dac Hien Vuong, W. Ruan, Beat Suter +1 more
2005Mechanisms of Development45 citations Open access
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Validation of novel automatic ultra-wideband radar for sleep apnea detection
Yong Zhou, D. Shu, Hang-Di Xu, Yuan-Hua Qiu +8 more
2020Journal of Thoracic Disease42 citations Open access
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Reactivation of IGFBP7 by DNA demethylation inhibits human colon cancer cell growth in vitro
Jie Lin, M. Lai, Qiong Huang, W. Ruan +2 more
2008Cancer Biology & Therapy41 citations Open access
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Bifocal is a downstream target of the Ste20-like serine/threonine kinase misshapen in regulating photoreceptor growth cone targeting in Drosophila.
W. Ruan, H. Long, Dac Hien Vuong, Yong Rao
2002Neuron38 citations Open access
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HSP60, a protein downregulated by IGFBP7 in colorectal carcinoma
W. Ruan, Ying-Hong Wang, Yu Ma, Xiao-Ming Xing +3 more
2010Journal of experimental & clinical cancer research : CR37 citations Open access
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Tumor suppressor gene insulin-like growth factor binding protein-related protein 1 (IGFBP-rP1) induces senescence-like growth arrest in colorectal cancer cells.
Yu Ma, B. Lu, W. Ruan, Hongqiang Wang +5 more
2008Experimental and molecular pathology (Print)33 citations
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IGFBP, a novel target of lung cancer?
Q. Hu, Yong Zhou, K. Ying, W. Ruan
2017Clinica chimica acta; international journal of clinical chemistry30 citations
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IGFBP-rP1 suppresses epithelial–mesenchymal transition and metastasis in colorectal cancer
S. Zhu, J. Zhang, F. Xu, E. Xu +4 more
2015Cell Death and Disease30 citations Open access
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Serum levels of IGFBP7 are elevated during acute exacerbation in COPD patients
W. Ruan, Minliang Wu, Liu-Hong Shi, Fengying Li +4 more
2017International Journal of COPD28 citations Open access
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Insulin-like growth factor binding protein-related protein 1 and cancer.
Shuzhen Zhu, Fang-Ying Xu, Jing Zhang, W. Ruan +1 more
2014Clinica chimica acta; international journal of clinical chemistry25 citations
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miR-1908 Dysregulation in Human Cancers
Jinze Shen, Yu-Chen Wu, W. Ruan, F. Zhu +1 more
2022Frontiers in Oncology22 citations Open access
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Abnormal expression of IGF-binding proteins, an initiating event in idiopathic pulmonary fibrosis?
W. Ruan, K. Ying
2010Pathology, Research and Practice19 citations
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Eiger-induced cell death relies on Rac1-dependent endocytosis
W. Ruan, A. Srinivasan, S. Lin, k-I Kara +1 more
2016Cell Death and Disease18 citations Open access
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IGFBP-rP1, a potential molecule associated with colon cancer differentiation
W. Ruan, Shuzhen Zhu, Hai-bing Wang, Fang-Ying Xu +3 more
2010Molecular Cancer17 citations Open access
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LINC00520: A Potential Diagnostic and Prognostic Biomarker in Cancer
Qiu-Dan Zhang, Jinze Shen, Yu-Chen Wu, W. Ruan +2 more
2022Frontiers in Immunology16 citations Open access
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Wengen, the Sole Tumour Necrosis Factor Receptor in Drosophila, Collaborates with Moesin to Control Photoreceptor Axon Targeting during Development
W. Ruan, Nicolás Unsain, J. Desbarats, E. Fon +1 more
2013PLoS ONE16 citations Open access
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Pulmonary vascular involvement of IgG4-related disease
Yong Zhou, Lingyan Shao, W. Ruan, Joy Q. Jin +3 more
2019Medicine14 citations Open access
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Detecting Dynamics of Hot Topics with Alluvial Diagrams: A Timeline Visualization
W. Ruan, Haiyan Hou, Zhigang Hu
2017Journal of Data and Information Science12 citations Open access
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Interaction between IGFBP7 and insulin: a theoretical and experimental study
W. Ruan, Zhengzhong Kang, Youzhao Li, Tianyang Sun +4 more
2016Scientific Reports12 citations Open access
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Aberrant expression of microRNA-4443 (miR-4443) in human diseases
Yunan Mao, Jinze Shen, Yu-Chen Wu, W. Ruan +2 more
2022Bioengineered11 citations Open access
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Downregulated level of insulin in COPD patients during AE; role beyond glucose control?
W. Ruan, Chao Yan, Hui-Qi Zhu, Shuwen Wang +4 more
2019International Journal of COPD9 citations Open access
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Tropheryma whipplei infection in the lung of a patient with long COVID: a case report
W. Ruan, Jing Xu, Fan Yang, Xiao-Hong Wu +1 more
2024BMC Infectious Diseases8 citations Open access
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Latcripin-13 domain induces apoptosis and cell cycle arrest at the G1 phase in human lung carcinoma A549 cells.
Jia Wang, X. Wan, Yifan Gao, M. Zhong +7 more
2016Oncology Report7 citations Open access
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Novel aspects of IGF1/insulin network in chronic inflammatory airway disease.
W. Ruan, Jing Deng, K. Ying
2019Current Medicinal Chemistry6 citations
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ResearchHSP 60 , a protein downregulated by IGFBP 7 in colorectal carcinoma
W. Ruan, Ying-Hong Wang, Yu Ma, Xiao-Ming Xing +3 more
20154 citations
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Uncertain Subgraph Query Processing over Uncertain Graphs
W. Ruan, Chao-Kun Wang, Lu Han, Zhuo Peng +1 more
2013Asia-Pacific Web Conference1 citations
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Probable Exophiala oligosperma-associated pulmonary granulomatous inflammation: a case report
Xiao-Hong Wu, Fan Yang, Zhi-Yao Xu, W. Ruan
2026BMC Infectious Diseases0 citations Open access
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Researcha protein downregulated by IGFBP7 in colorectal carcinoma
W. Ruan, Ying-Hong Wang, Yu Ma, Xiao-Ming Xing +3 more
20100 citations
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Invited critical review Actin, a reliable marker of internal control?
W. Ruan, M. Lai
20070 citations
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