Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

T. Dunkern · SciRah

Researcher profile · Semantic Scholar

T. Dunkern

Share profile

T. Dunkern — researcher profile on SciRah

h-index: 18
Works: 30
Citations: 1,216

Most-cited papers

Phosphodiesterase 1 Upregulation in Pulmonary Arterial Hypertension: Target for Reverse-Remodeling Therapy
R. Schermuly, S. Pullamsetti, G. Kwapiszewska, R. Dumitrascu +14 more
2007Circulation156 citations Open access
Semantic Scholar
Inhibition of TGF-beta induced lung fibroblast to myofibroblast conversion by phosphodiesterase inhibiting drugs and activators of soluble guanylyl cyclase.
T. Dunkern, Daniel Feurstein, G. Rossi, F. Sabatini +1 more
2007European Journal of Pharmacology130 citations
Semantic Scholar
Ultraviolet light-induced DNA damage triggers apoptosis in nucleotide excision repair-deficient cells via Bcl-2 decline and caspase-3/-8 activation
T. Dunkern, G. Fritz, B. Kaina
2001Oncogene120 citations
Semantic Scholar
Cell proliferation and DNA breaks are involved in ultraviolet light-induced apoptosis in nucleotide excision repair-deficient Chinese hamster cells.
T. Dunkern, B. Kaina
2002Molecular Biology of the Cell95 citations Open access
Semantic Scholar
BER, MGMT, and MMR in defense against alkylation-induced genotoxicity and apoptosis.
Bernd Kaina, Kirsten Ochs, S. Grösch, G. Fritz +4 more
2001Progress in Nucleic Acid Research and Molecular Biology92 citations
Semantic Scholar
Ionizing radiation but not anticancer drugs causes cell cycle arrest and failure to activate the mitochondrial death pathway in MCF-7 breast carcinoma cells
R. Jänicke, I. Engels, T. Dunkern, B. Kaina +2 more
2001Oncogene87 citations Open access
Semantic Scholar
Resistance of p53 knockout cells to doxorubicin is related to reduced formation of DNA strand breaks rather than impaired apoptotic signaling.
T. Dunkern, I. Wedemeyer, Manuela Baumgärtner, G. Fritz +1 more
2003DNA Repair70 citations
Semantic Scholar
The effect of Sildenafil on human platelet secretory function is controlled by a complex interplay between phosphodiesterases 2, 3 and 5.
T. Dunkern, A. Hatzelmann
2005Cellular Signalling62 citations
Semantic Scholar
The differential impact of PDE4 subtypes in human lung fibroblasts on cytokine‐induced proliferation and myofibroblast conversion
J. Selige, A. Hatzelmann, T. Dunkern
2011Journal of Cellular Physiology59 citations
Semantic Scholar
Characterization of inhibitors of phosphodiesterase 1C on a human cellular system
T. Dunkern, A. Hatzelmann
2007The FEBS Journal40 citations Open access
Semantic Scholar
Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.
Alice Krebs, T. Waldmann, M. F. Wilks, B. V. van Vugt-Lussenburg +32 more
2019ALTEX38 citations Open access
Semantic Scholar
Cytokine‐dependent balance of mitogenic effects in primary human lung fibroblasts related to cyclic AMP signaling and phosphodiesterase 4 inhibition
J. Selige, H. Tenor, A. Hatzelmann, T. Dunkern
2010Journal of Cellular Physiology35 citations Open access
Semantic Scholar
Combined anti-inflammatory effects of β2-adrenergic agonists and PDE4 inhibitors on astrocytes by upregulation of intracellular cAMP.
S. H. Christiansen, J. Selige, T. Dunkern, A. Rassov +1 more
2011Neurochemistry International30 citations Open access
Semantic Scholar
Cisplatin-induced apoptosis in 43-3B and 27-1 cells defective in nucleotide excision repair.
T. Dunkern, G. Fritz, B. Kaina
2001Mutation research28 citations
Semantic Scholar
Phosphodiesterase-5 inhibitors have distinct effects on the hemodynamics of the liver
Leonie Halverscheid, P. Deibert, R. Schmidt, H. Blum +3 more
2009BMC Gastroenterology27 citations Open access
Semantic Scholar
The HMG-CoA reductase inhibitor lovastatin protects cells from the antineoplastic drugs doxorubicin and etoposide.
R. V. Bardeleben, T. Dunkern, B. Kaina, G. Fritz
2002International Journal of Molecular Medicine23 citations
Semantic Scholar
Apoptosis induced by MNNG in human TK6 lymphoblastoid cells is p53 and Fas/CD95/Apo-1 related.
T. Dunkern, W. Roos, B. Kaina
2003Mutation research22 citations
Semantic Scholar
Quantification of apoptosis induction by doxorubicin in three types of human mammary carcinoma spheroids.
T. Dunkern, W. Mueller-Klieser
1999Anticancer Research18 citations
Semantic Scholar
Virtual and experimental high-throughput screening (HTS) in search of novel inosine 5′-monophosphate dehydrogenase II (IMPDH II) inhibitors
T. Dunkern, Arati Prabhu, P. Kharkar, H. Goebel +4 more
2012Journal of Computer-Aided Molecular Design15 citations
Semantic Scholar
The GAF-tandem domain of phosphodiesterase 5 as a potential drug target.
J. Schultz, T. Dunkern, Elvira Gawlitta-Gorka, G. Sorg
2011Handbook of Experimental Pharmacology14 citations
Semantic Scholar
Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors.
J. Alen, M. Schade, M. Wagener, F. Christian +5 more
2019Journal of Medicinal Chemistry13 citations Open access
Semantic Scholar
Design, synthesis and biological evaluation of novel inosine 5′-monophosphate dehydrogenase (IMPDH) inhibitors
T. Dunkern, S. Chavan, D. Bankar, Anuja Patil +8 more
2014Journal of Enzyme Inhibition and Medicinal Chemistry12 citations Open access
Semantic Scholar
Central IRAK-4 kinase inhibition for the treatment of pain following nerve injury in rats.
Katrien Pletinckx, Duygu Krings, André Welbers, D. Rider +1 more
2020Brain, behavior, and immunity9 citations
Semantic Scholar
Erratum to Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data.
Alice Krebs, T. Waldmann, M. Wilks, B. V. van Vugt-Lussenburg +32 more
2020ALTEX8 citations Open access
Semantic Scholar
Differential changes in purine nucleotides after Doxorubicin treatment of human cancer cells in vitro.
S. Walenta, B. Feigk, I. Wachsmuth, T. Dunkern +2 more
2002International Journal of Oncology8 citations
Semantic Scholar
Inhibiting the immunoproteasome's β5i catalytic activity affects human peripheral blood‐derived immune cell viability
Katrien Pletinckx, Silke Vaßen, Ilka Schlusche, S. Nordhoff +2 more
2019Pharmacology Research & Perspectives5 citations Open access
Semantic Scholar
Virtual and experimental high-throughput screening ( HTS ) in search of novel inosine 5 ′-monophosphate dehydrogenase II ( IMPDH II ) inhibitors
T. Dunkern, Arati Prabhu, P. Kharkar, H. Goebel +4 more
20120 citations
Semantic Scholar
Composés de 3,4,4A,10B-tétrahydro-1H-thiopyrano-[4,3-c]isoquinoline
D. Flockerzi, Thomas Stengel, Alexander Mann, Harald Ohmer +12 more
20100 citations
Semantic Scholar
S1299 Low-Dose Phosphodiesterase-5-Inhibitors Have a Distinct Effect On Hepatic Hemodynamics
Leonie Halverscheid, P. Deibert, T. Dunkern, R. Schmidt +2 more
20080 citations
Semantic Scholar
New Use for PDE5 inhibitors.
T. Dunkern, A. Ghofrani, F. Grimminger, M. Kaps +2 more
20050 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

B. Kaina×7
Invite
B. Kaina — researcher profile on SciRah
A. Hatzelmann×6
Invite
A. Hatzelmann — researcher profile on SciRah
G. Fritz×4
Invite
G. Fritz — researcher profile on SciRah
J. Selige×3
Invite
J. Selige — researcher profile on SciRah

×3

Invite

Arati Prabhu — researcher profile on SciRah

Invite

P. Kharkar — researcher profile on SciRah

Invite

H. Goebel — researcher profile on SciRah

Edith Rolser×3

Invite

Edith Rolser — researcher profile on SciRah

Waltraud Burckhard-Boer×3

Invite

Waltraud Burckhard-Boer — researcher profile on SciRah

Premkumar Arumugam×3

Invite

Premkumar Arumugam — researcher profile on SciRah

Mahindra T. Makhija×3

Invite

Mahindra T. Makhija — researcher profile on SciRah

Invite

C. Schudt — researcher profile on SciRah