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E. McDade · SciRah

Researcher profile · Semantic Scholar

E. McDade

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E. McDade — researcher profile on SciRah

h-index: 48
Works: 365
Citations: 16K

Most-cited papers

Revised criteria for diagnosis and staging of Alzheimer's disease: Alzheimer's Association Workgroup
C. Jack, J. Andrews, Thomas G. Beach, Teresa Buracchio +16 more
2024Alzheimer's & Dementia2,644 citations Open access
Semantic Scholar
Revised criteria for the diagnosis and staging of Alzheimer’s disease
C. Jack, J. Andrews, Thomas G. Beach, Teresa Buracchio +16 more
2024Nature Medicine214 citations Open access
Semantic Scholar
Timing of biomarker changes in sporadic Alzheimer disease in estimated years from symptom onset
Yan Li, Daniel Yen, Rachel Hendrix, B. Gordon +18 more
2024Annals of Neurology81 citations Open access
Semantic Scholar
Predicting onset of symptomatic Alzheimerʼs disease with plasma p-tau217 clocks
K. K. Petersen, Marta Milà-Alomà, Yan Li, Lian-Lian Du +26 more
2026Nature Medicine40 citations Open access
Semantic Scholar
α‐Synuclein seed amplification assay detects Lewy body co‐pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden
J. Levin, Simone Baiardi, C. Quadalti, Marcello Rossi +42 more
2024Alzheimer's & Dementia37 citations Open access
Semantic Scholar
Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer’s disease: a cross-sectional study
Julie K. Wisch, Nicole S. Mckay, Anna H. Boerwinkle, James T. Kennedy +46 more
2024Lancet Neurology34 citations Open access
Semantic Scholar
Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer’s disease
Anna Hofmann, Lisa M. Häsler, Marius Lambert, Stephan A. Kaeser +31 more
2024Nature Communications31 citations Open access
Semantic Scholar
Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer’s disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial
Randall J. Bateman, Yan Li, E. McDade, J. Llibre-Guerra +64 more
2024medRxiv30 citations Open access
Semantic Scholar
Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease
O. Wagemann, Haiyan Liu, Guo-Qiao Wang, Xinyu Shi +46 more
2024JAMA Neurology29 citations Open access
Semantic Scholar
Gamma-secretase activity, clinical features, and biomarkers in autosomal dominant Alzheimer’s disease: cross-sectional and longitudinal analyses of an observational study
Stephanie A. Schultz, Lei Liu, A. Schultz, Colleen D. Fitzpatrick +24 more
2024Lancet Neurology27 citations Open access
Semantic Scholar
Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia
J. Llibre-Guerra, M. V. Fernández, N. Joseph-Mathurin, Shi-Jia Bian +24 more
2025Nature Medicine26 citations Open access
Semantic Scholar
Comparison of cerebrospinal fluid, plasma and neuroimaging biomarker utility in Alzheimer’s disease
Karin L. Meeker, Patrick H. Luckett, N. Barthélemy, Diana A. Hobbs +18 more
2024Brain Communications25 citations Open access
Semantic Scholar
A framework for translating tauopathy therapeutics: Drug discovery to clinical trials
H. Feldman, Jeffrey L. Cummings, A. Boxer, A. Staffaroni +29 more
2024Alzheimer's & Dementia23 citations Open access
Semantic Scholar
Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer’s disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial
Randall J. Bateman, Yan Li, E. McDade, J. Llibre-Guerra +64 more
2025Lancet Neurology22 citations Open access
Semantic Scholar
The landscape of autosomal-dominant Alzheimer’s disease: global distribution and age of onset
Haiyan Liu, Thomas W. Marsh, Xinyu Shi, Alan E. Renton +48 more
2025Brain : a journal of neurology21 citations Open access
Semantic Scholar
Statistical considerations when estimating time‐saving treatment effects in Alzheimer's disease clinical trials
Guo-Qiao Wang, G. Cutter, N. Oxtoby, Guogen Shan +10 more
2024Alzheimer's & Dementia18 citations Open access
Semantic Scholar
Adapting prescribing criteria for amyloid‐targeted antibodies for adults with Down syndrome
H. Hillerstrom, Richard A Fisher, M. Janicki, B. Chicoine +18 more
2024Alzheimer's & Dementia17 citations Open access
Semantic Scholar
Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer’s disease
Phoebe Valdes, Andrew B. Caldwell, Qing Liu, Michael Q. Fitzgerald +140 more
2025Alzheimer's Research & Therapy16 citations Open access
Semantic Scholar
Presenilin‐1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage
N. Joseph-Mathurin, R. Feldman, Rui-Jin Lu, Z. Shirzadi +54 more
2024Alzheimer's & Dementia15 citations Open access
Semantic Scholar
Systematic analysis of cellular crosstalk reveals a role for SEMA6D-TREM2 regulating microglial function in Alzheimer’s disease
Ricardo D’Oliveira Albanus, Gina M. Finan, L. Brase, Nicholas Sweeney +27 more
2025Science Translational Medicine13 citations Open access
Semantic Scholar
Examining amyloid reduction as a surrogate endpoint through latent class analysis using clinical trial data for dominantly inherited Alzheimer's disease
Guo-Qiao Wang, Yan Li, C. Xiong, T. Benzinger +21 more
2024Alzheimer's & Dementia13 citations Open access
Semantic Scholar
Early increase of the synaptic blood marker β‐synuclein in asymptomatic autosomal dominant Alzheimer's disease
P. Oeckl, B. Mayer, Randall J. Bateman, G. Day +16 more
2025Alzheimer's & Dementia10 citations Open access
Semantic Scholar
Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference
Bess Frost, J. Rowe, Rufus Akinyemi, J. Abisambra +39 more
2025Alzheimer's & Dementia10 citations Open access
Semantic Scholar
Molecular neuroimaging in dominantly inherited versus sporadic early-onset Alzheimer’s disease
L. Iaccarino, J. Llibre-Guerra, E. McDade, Lauren Edwards +33 more
2024Brain Communications10 citations Open access
Semantic Scholar
Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways
Yuanyuan Shen, M. Ali, J. Timsina, Ciyang Wang +32 more
2024medRxiv9 citations Open access
Semantic Scholar
Targeting tau in Alzheimer’s Disease: rationale, approach and challenges
A. Aslanyan, M. Foiani, T. A. Giovannucci, E. McDade +5 more
2026Molecular Neurodegeneration8 citations Open access
Semantic Scholar
15 Years of Longitudinal Genetic, Clinical, Cognitive, Imaging, and Biochemical Measures in DIAN
Alisha J. Daniels, E. McDade, J. Llibre-Guerra, Cheng-Jie Xiong +38 more
2024medRxiv8 citations Open access
Semantic Scholar
Novel Non-Linear Models for Clinical Trial Analysis with Longitudinal Data: A Tutorial Using SAS for Both Frequentist and Bayesian Methods
Guo-Qiao Wang, Whedy Wang, Brian Mangal, Yijie Liao +7 more
2024Statistics in Medicine8 citations Open access
Semantic Scholar
The CentiMarker project: Standardizing quantitative Alzheimer's disease fluid biomarkers for biologic interpretation
Guo-Qiao Wang, Yan Li, Cheng-Jie Xiong, Yuchen Cao +13 more
2025Alzheimer's & Dementia7 citations Open access
Semantic Scholar
Evaluating pathogenicity of variants of unknown significance in APP, PSEN1, and PSEN2
Jacob Marsh, Guangming Huang, Kevin M Bowling, Alan E. Renton +9 more
2025Neurotherapeutics7 citations Open access
Semantic Scholar
Unlocking Cognitive Analysis Potential in Alzheimer’s Disease Clinical Trials: Investigating Hierarchical Linear Models for Analyzing Novel Measurement Burst Design Data
Guo-Qiao Wang, Jason J. Hassenstab, Yan Li, A. Aschenbrenner +4 more
2024Statistics in Medicine7 citations
Semantic Scholar
Immunohistochemical evaluation of a trial of gantenerumab or solanezumab in dominantly inherited Alzheimer disease
Charles D. Chen, Erin E. Franklin, Yan Li, N. Joseph-Mathurin +44 more
2025Acta Neuropathologica6 citations Open access
Semantic Scholar
Genetically determined Alzheimer's disease research advances: The Down Syndrome & Autosomal Dominant Alzheimer's Disease 2024 Conference
Neus Falgàs, Lucía Maure-Blesa, B. Ances, Lisi Flores-Aguilar +54 more
2025Alzheimer's & Dementia6 citations Open access
Semantic Scholar
The relationship of soluble tau species with Alzheimer's disease amyloid plaque removal and tau pathology
E. McDade, N. Barthélemy, Guo-Qiao Wang, Yan Li +45 more
2025Alzheimer's & Dementia6 citations Open access
Semantic Scholar
Comparative gene regulatory networks modulating APOE expression in microglia and astrocytes
L. Brase, Yanbo Yu, E. McDade, O. Harari +1 more
2024medRxiv6 citations Open access
Semantic Scholar
Evolution of white matter hyperintensity segmentation methods and implementation over the past two decades; an incomplete shift towards deep learning
Maryam Rahmani, Donna L. Dierker, Lauren H Yaeger, A. Saykin +55 more
2024Brain Imaging and Behavior6 citations Open access
Semantic Scholar
Ubiquitin–proteasome system in the different stages of dominantly inherited Alzheimer's disease
Haiyan Liu, Quoc Bui, Jason J. Hassenstab, B. Gordon +32 more
2025Alzheimer's & Dementia5 citations Open access
Semantic Scholar
Regional effects of gantenerumab on neuroimaging biomarkers in the DIAN‐TU‐001 trial
Austin A. McCullough, Charles D. Chen, B. Gordon, N. Joseph-Mathurin +47 more
2025Alzheimer's & Dementia5 citations Open access
Semantic Scholar
Ubiquitin-Proteasome System in the Different Stages of Dominantly Inherited Alzheimer’s Disease
E. McDade, Haiyan Liu, Quoc Bui, Jason J. Hassenstab +34 more
2024Research Square5 citations
Semantic Scholar
GWAS meta-analysis of CSF Alzheimer's disease biomarkers 18,948 individuals reveal novel loci and genes regulating lipid metabolism, brain volume and autophagy
C. Cruchaga, J. Timsina, Chenyang Jiang, Daniel L. McCartney +149 more
2025Research Square4 citations Open access
Semantic Scholar
Longitudinal associations between exercise and biomarkers in autosomal dominant Alzheimer's disease
Kelsey R. Sewell, J. Doecke, Cheng-Jie Xiong, T. Benzinger +32 more
2024Alzheimer's & Dementia4 citations Open access
Semantic Scholar
Etalanetug (E2814) in dominantly inherited Alzheimer’s disease: an open-label phase 1b/2 study to assess safety and target engagement in participants with mild to moderate cognitive impairment
Erica Andreozzi, Takuya Yagi, Kristin R. Wildsmith, S. Rawal +17 more
2026Alzheimer's Research & Therapy3 citations Open access
Semantic Scholar
Impact of genetic counseling and testing in individuals at high risk of familial Alzheimer's disease from Latin America: a non‐randomized controlled trial
P. Bagnati, Marisol Londoño Castaño, M. L. Fernández, Beatriz Mora Henao +21 more
2025Alzheimer's & Dementia3 citations Open access
Semantic Scholar
Increasing hub disruption parallels dementia severity in autosomal dominant Alzheimer’s disease
J. C. Tu, Peter R. Millar, Jeremy F. Strain, Andy Eck +22 more
2024Network Neuroscience3 citations Open access
Semantic Scholar
Sample size estimates for biomarker-based outcome measures in clinical trials in autosomal dominant Alzheimer's disease
D. Cash, K. E. Morgan, A. O'Connor, T. Veale +23 more
2024medRxiv3 citations Open access
Semantic Scholar
Axonal damage and inflammation response are biological correlates of decline in small-world values: a cohort study in autosomal dominant Alzheimer’s disease
L. Vermunt, C. Sutphen, E. Dicks, D. D. de Leeuw +34 more
2024Brain Communications3 citations Open access
Semantic Scholar
The CentiMarker Project: Standardizing Quantitative Alzheimer’s disease Fluid Biomarkers for Biologic Interpretation
Guo-Qiao Wang, Yan Li, Cheng-Jie Xiong, Yuchen Cao +13 more
2024medRxiv3 citations Open access
Semantic Scholar
15 years of longitudinal genetic, clinical, cognitive, imaging, and biochemical measures in DIAN
Alisha J. Daniels, E. McDade, J. Llibre-Guerra, Cheng-Jie Xiong +103 more
2026npj Dementia2 citations Open access
Semantic Scholar
Target product profiles for treatments to delay or prevent symptomatic Alzheimer's disease.
Jeffery Cummings, M. Agadjanyan, Maureen A. Barry, L. Corey +14 more
2026Nature Medicine2 citations
Semantic Scholar
Drug Development.
Jin Zhou, Erica Andreozzi, J. Llibre-Guerra, D. Clifford +6 more
2025Alzheimer's & Dementia2 citations Open access
Semantic Scholar

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