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O. Itzhaki · SciRah

Researcher profile · Semantic Scholar

O. Itzhaki

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O. Itzhaki — researcher profile on SciRah

h-index: 26
Works: 89
Citations: 2,906

Most-cited papers

Clinical Responses in a Phase II Study Using Adoptive Transfer of Short-term Cultured Tumor Infiltration Lymphocytes in Metastatic Melanoma Patients
M. Besser, R. Shapira-Frommer, A. Treves, D. Zippel +16 more
2010Clinical Cancer Research476 citations Open access
Semantic Scholar
Adoptive Transfer of Tumor-Infiltrating Lymphocytes in Patients with Metastatic Melanoma: Intent-to-Treat Analysis and Efficacy after Failure to Prior Immunotherapies
M. Besser, R. Shapira-Frommer, O. Itzhaki, A. Treves +16 more
2013Clinical Cancer Research348 citations Open access
Semantic Scholar
Gamma-Delta CAR-T Cells Show CAR-Directed and Independent Activity Against Leukemia
Meir Rozenbaum, Amilia Meir, Yarden Aharony, O. Itzhaki +4 more
2020Frontiers in Immunology210 citations Open access
Semantic Scholar
Establishment and Large-scale Expansion of Minimally cultured “Young” Tumor Infiltrating Lymphocytes for Adoptive Transfer Therapy
O. Itzhaki, E. Hovav, Yaara Ziporen, Daphna Levy +10 more
2011Journal of immunotherapy158 citations
Semantic Scholar
MDR1 expression identifies human melanoma stem cells.
G. Keshet, I. Goldstein, O. Itzhaki, K. Cesarkas +6 more
2008Biochemical and Biophysical Research Communications - BBRC131 citations
Semantic Scholar
Minimally Cultured or Selected Autologous Tumor-infiltrating Lymphocytes After a Lympho-depleting Chemotherapy Regimen in Metastatic Melanoma Patients
M. Besser, R. Shapira-Frommer, A. Treves, D. Zippel +14 more
2009Journal of immunotherapy127 citations
Semantic Scholar
Locally produced CD19 CAR T cells leading to clinical remissions in medullary and extramedullary relapsed acute lymphoblastic leukemia
E. Jacoby, B. Bielorai, A. Avigdor, O. Itzhaki +12 more
2018American journal of hematology/oncology116 citations Open access
Semantic Scholar
Regulation of Cancer Aggressive Features in Melanoma Cells by MicroRNAs
E. Greenberg, Liat Hershkovitz, O. Itzhaki, S. Hajdu +10 more
2011PLoS ONE87 citations Open access
Semantic Scholar
Establishment of adoptive cell therapy with tumor infiltrating lymphocytes for non-small cell lung cancer patients
Ronny Ben-Avi, Ronit Farhi, A. Ben-nun, Marina Gorodner +5 more
2018Cancer Immunology and Immunotherapy75 citations Open access
Semantic Scholar
Selection of Shared and Neoantigen-Reactive T Cells for Adoptive Cell Therapy Based on CD137 Separation
Sivan Seliktar-Ofir, Efrat Merhavi-Shoham, O. Itzhaki, Sharon Yunger +3 more
2017Frontiers in Immunology65 citations Open access
Semantic Scholar
Comparison of non-myeloablative lymphodepleting preconditioning regimens in patients undergoing adoptive T cell therapy
Abraham Nissani, Shaked Lev-Ari, Tomer Meirson, E. Jacoby +7 more
2021Journal for ImmunoTherapy of Cancer63 citations Open access
Semantic Scholar
Nicotinamide Inhibits Vasculogenic Mimicry, an Alternative Vascularization Pathway Observed in Highly Aggressive Melanoma
O. Itzhaki, E. Greenberg, B. Shalmon, A. Kubi +8 more
2013PLoS ONE56 citations Open access
Semantic Scholar
Adoptive Cell Therapy for Metastatic Melanoma.
Efrat Merhavi-Shoham, O. Itzhaki, G. Markel, J. Schachter +1 more
2017Cancer Journal55 citations
Semantic Scholar
A novel immune resistance mechanism of melanoma cells controlled by the ADAR1 enzyme
Gilli Galore-Haskel, Yael Nemlich, E. Greenberg, S. Ashkenazi +10 more
2015OncoTarget53 citations Open access
Semantic Scholar
Head-to-head comparison of in-house produced CD19 CAR-T cell in ALL and NHL patients
O. Itzhaki, E. Jacoby, Abraham Nissani, M. Levi +12 more
2020Journal for ImmunoTherapy of Cancer52 citations Open access
Semantic Scholar
Epigenetic Profiling and Response to CD19 Chimeric Antigen Receptor T-Cell Therapy in B-Cell Malignancies
C. García-Prieto, Lorea Villanueva, Alberto Bueno-Costa, V. Davalos +22 more
2021Journal of the National Cancer Institute49 citations Open access
Semantic Scholar
T-ICAHT: grading and prognostic impact of thrombocytopenia after CAR T-cell therapy
K. Rejeski, Jaime Sanz, Teng Fei, Monica S. Nair +34 more
2025Blood43 citations Open access
Semantic Scholar
A comparative analysis of total serum miRNA profiles identifies novel signature that is highly indicative of metastatic melanoma: a pilot study
E. Greenberg, M. Besser, E. Ben-Ami, R. Shapira-Frommer +10 more
2013Biomarkers43 citations
Semantic Scholar
Tumor-infiltrating lymphocytes from human prostate tumors reveal anti-tumor reactivity and potential for adoptive cell therapy
Sharon Yunger, Assaf Barel, Li-at Zeltzer, E. Fridman +6 more
2019Oncoimmunology40 citations Open access
Semantic Scholar
CD-19 CAR-T cells for polyrefractory rheumatoid arthritis
M. Lidar, D. Rimar, Paula David, E. Jacoby +12 more
2024Annals of the Rheumatic Diseases39 citations
Semantic Scholar
Preclinical evaluation of adoptive cell therapy for patients with metastatic renal cell carcinoma.
G. Markel, T. Cohen-Sinai, M. Besser, K. Oved +8 more
2009Anticancer Research38 citations
Semantic Scholar
Impact of cryopreservation on CAR T production and clinical response
Karin Brezinger-Dayan, O. Itzhaki, Jenny Melnichenko, A. Kubi +5 more
2022Frontiers in Oncology35 citations Open access
Semantic Scholar
Comprehensive single institute experience with melanoma TIL: Long term clinical results, toxicity profile, and prognostic factors of response
M. Besser, O. Itzhaki, Guy Ben-Betzalel, D. Zippel +13 more
2020Molecular Carcinogenesis35 citations
Semantic Scholar
The tumor microenvironment: part 1.
J. Leibovici, O. Itzhaki, M. Huszar, J. Sinai
2011Immunotherapy31 citations
Semantic Scholar
Parameters of long‐term response with CD28‐based CD19 chimaeric antigen receptor‐modified T cells in children and young adults with B‐acute lymphoblastic leukaemia
E. Jacoby, B. Bielorai, D. Hutt, O. Itzhaki +4 more
2022British Journal of Haematology27 citations
Semantic Scholar
Ageing-apoptosis relation in murine spleen.
O. Itzhaki, E. Skutelsky, T. Kaptzan, J. Sinai +3 more
2003Mechanisms of Ageing and Development27 citations
Semantic Scholar
Feasibility of leukapheresis for CAR T-cell production in heavily pre-treated pediatric patients.
D. Hutt, B. Bielorai, B. Baturov, Inna Z'orbinski +6 more
2020Transfusion and Apheresis Science26 citations
Semantic Scholar
Molecular and Functional Signatures Associated with CAR T Cell Exhaustion and Impaired Clinical Response in Patients with B Cell Malignancies
Katia Beider, O. Itzhaki, J. Schachter, A. H. Grushchenko-Polaq +12 more
2022Cells24 citations Open access
Semantic Scholar
Membrane-attached Cytokines Expressed by mRNA Electroporation Act as Potent T-Cell Adjuvants
Hadas Weinstein-Marom, A. Pato, Noam Levin, Keren Susid +6 more
2016Journal of immunotherapy24 citations
Semantic Scholar
Adoptive T-cell transfer in melanoma.
O. Itzhaki, Daphna Levy, D. Zikich, A. Treves +3 more
2013Immunotherapy24 citations
Semantic Scholar
Adoptive cell therapy for metastatic melanoma patients: pre-clinical development at the Sheba Medical Center.
M. Besser, A. Treves, O. Itzhaki, I. Hardan +6 more
2006The Israel Medical Association journal : IMAJ20 citations
Semantic Scholar
Anti-CD19 chimeric antigen receptor T-cell therapy has less efficacy in Richter transformation than in de novo large B-cell lymphoma and transformed low-grade B-cell lymphoma
O. Benjamini, S. Fried, R. Shouval, Jessica R. Flynn +23 more
2024Haematologica18 citations Open access
Semantic Scholar
Point of care CD19 chimeric antigen receptor (CAR) T-cells for relapsed/refractory acute myeloid leukemia (AML) with aberrant CD19 antigen expression.
I. Danylesko, N. Shem-Tov, R. Yerushalmi, E. Jacoby +6 more
2024Current Research in Translational Medicine18 citations
Semantic Scholar
Improved CAR-T cell activity associated with increased mitochondrial function primed by galactose
Golda Gross, Suha Alkadieri, Amilia Meir, O. Itzhaki +7 more
2023bioRxiv18 citations Open access
Semantic Scholar
Tissue Harvesting for Adoptive Tumor Infiltrating Lymphocyte Therapy in Metastatic Melanoma
D. Zippel, Orli Friedman-Eldar, S. Rayman, D. Hazzan +6 more
2019Anticancer Research18 citations Open access
Semantic Scholar
Efficacy of anti-angiogenic treatment of tumors in old versus young mice.
T. Kaptzan, E. Skutelsky, O. Itzhaki, J. Sinai +7 more
2006Mechanisms of Ageing and Development18 citations
Semantic Scholar
Age-adjusted antitumoral therapy based on the demonstration of increased apoptosis as a mechanism underlying the reduced malignancy of tumors in the aged.
O. Itzhaki, T. Kaptzan, E. Skutelsky, J. Sinai +6 more
2004Biochimica et Biophysica Acta18 citations Open access
Semantic Scholar
Designing ageing conditions in tumour microenvironment-a new possible modality for cancer treatment.
J. Leibovici, O. Itzhaki, T. Kaptzan, E. Skutelsky +6 more
2009Mechanisms of Ageing and Development17 citations
Semantic Scholar
Age-dependent differences in the efficacy of cancer immunotherapy in C57BL and AKR mouse strains.
T. Kaptzan, E. Skutelsky, O. Itzhaki, J. Sinai +4 more
2004Experimental Gerontology16 citations
Semantic Scholar
Serum CEACAM1 Elevation Correlates with Melanoma Progression and Failure to Respond to Adoptive Cell Transfer Immunotherapy
R. Ortenberg, S. Sapoznik, D. Zippel, R. Shapira-Frommer +6 more
2015Journal of Immunological Research14 citations Open access
Semantic Scholar
Differential regulation of aggressive features in melanoma cells by members of the miR-17-92 complex
E. Greenberg, S. Hajdu, Yael Nemlich, R. Cohen +5 more
2014Open Biology14 citations Open access
Semantic Scholar
Metastatic Lung Lesions as a Preferred Resection Site for Immunotherapy With Tumor Infiltrating Lymphocytes
Ronny Ben-Avi, O. Itzhaki, D. Simansky, D. Zippel +4 more
2016Journal of immunotherapy13 citations
Semantic Scholar
Macrophage-recognized molecules of apoptotic cells are expressed at higher levels in AKR lymphoma of aged as compared to young mice.
O. Itzhaki, Ehud Skutelsky, T. Kaptzan, A. Siegal +5 more
2000Advances in Experimental Medicine and Biology13 citations
Semantic Scholar
HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion.
Yoav Chemla, O. Itzhaki, Stav Melamed, Chen Weller +65 more
2025Cell12 citations Open access
Semantic Scholar
Membrane anchored IL-18 linked to constitutively active TLR4 and CD40 improves human T cell antitumor capacities for adoptive cell therapy
Dayana Blokon-Kogan, Maya Levi-Mann, Lior Malka-Levy, O. Itzhaki +7 more
2022Journal for ImmunoTherapy of Cancer11 citations Open access
Semantic Scholar
Potent Activation of Human T Cells by mRNA Encoding Constitutively Active CD40
Noam Levin, Hadas Weinstein-Marom, A. Pato, O. Itzhaki +5 more
2018Journal of Immunology11 citations Open access
Semantic Scholar
Point-of-care CAR T-cell therapy as salvage strategy for out-of-specification tisagenlecleucel
S. Fried, R. Shouval, N. Varda‐Bloom, M. Besser +11 more
2022Leukemia and Lymphoma10 citations
Semantic Scholar
MYC induces immunotherapy and interferon-γ resistance through downregulation of JAK2.
E. Markovits, Ortal Harush, E. Baruch, E. Shulman +14 more
2023Cancer immunology research8 citations Open access
Semantic Scholar
Genetic Modification of Tumor-Infiltrating Lymphocytes via Retroviral Transduction
Hadas Weinstein-Marom, G. Gross, M. Levi, Hadar Brayer +3 more
2021Frontiers in Immunology8 citations Open access
Semantic Scholar
Targeting the tumor microenvironment by immunotherapy: part 2.
J. Leibovici, O. Itzhaki, M. Huszar, J. Sinai
2011Immunotherapy8 citations
Semantic Scholar

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