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D. Kwiatkowski · SciRah

Researcher profile · Semantic Scholar

D. Kwiatkowski

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D. Kwiatkowski — researcher profile on SciRah

h-index: 125
Works: 476
Citations: 62K

Most-cited papers

Neoadjuvant atezolizumab for resectable non-small cell lung cancer: an open-label, single-arm phase II trial
J. Chaft, F. Oezkan, M. Kris, P. Bunn +32 more
2022Nature Medicine233 citations Open access
Semantic Scholar
MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP-Deleted Cancer
Lars D. Engstrom, Ruth Aranda, Laurie Waters, K. Moya +28 more
2023Cancer Discovery166 citations Open access
Semantic Scholar
Distribution of KRAS G12C Somatic Mutations across Race, Sex, and Cancer Type.
A. Nassar, E. Adib, D. Kwiatkowski
2021New England Journal of Medicine162 citations Open access
Semantic Scholar
nab-Sirolimus for Patients With Malignant Perivascular Epithelioid Cell Tumors
A. Wagner, V. Ravi, R. Riedel, K. Ganjoo +13 more
2021Journal of Clinical Oncology148 citations Open access
Semantic Scholar
Association of Machine Learning-Based Assessment of Tumor-Infiltrating Lymphocytes on Standard Histologic Images With Outcomes of Immunotherapy in Patients With NSCLC.
M. Rakaee, E. Adib, B. Ricciuti, L. Sholl +18 more
2022JAMA Oncology135 citations
Semantic Scholar
mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion
Heng-Jia Liu, H. Du, D. Khabibullin, Mahsa Zarei +4 more
2023Nature Communications109 citations Open access
Semantic Scholar
Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes to immune checkpoint inhibitors
A. Nassar, E. Adib, Sarah Abou Alaiwi, T. El Zarif +28 more
2022Cancer Cell92 citations Open access
Semantic Scholar
CDKN2A Alterations and Response to Immunotherapy in Solid Tumors
E. Adib, A. Nassar, E. Akl, S. A. Alaiwi +12 more
2021Clinical Cancer Research92 citations Open access
Semantic Scholar
TSC2 pathogenic variants are predictive of severe clinical manifestations in TSC infants: results of the EPISTOP study
B. Ogorek, L. Hamieh, H. Hulshof, Kathryn D. Lasseter +26 more
2020Genetics in Medicine86 citations Open access
Semantic Scholar
Tertiary lymphoid structure score: a promising approach to refine the TNM staging in resected non-small cell lung cancer
M. Rakaee, T. Kilvaer, S. Jamaly, T. Berg +11 more
2021British Journal of Cancer83 citations Open access
Semantic Scholar
Single Cell Transcriptomic Analysis Identifies a Unique Pulmonary Lymphangioleiomyomatosis Cell.
M. Guo, Jane J. Yu, Anne-Karina T. Perl, K. Wikenheiser-Brokamp +14 more
2020American Journal of Respiratory and Critical Care Medicine78 citations Open access
Semantic Scholar
Variation in targetable genomic alterations in non-small cell lung cancer by genetic ancestry, sex, smoking history, and histology
E. Adib, A. Nassar, Sarah Abou Alaiwi, S. Groha +7 more
2022Genome Medicine73 citations Open access
Semantic Scholar
PS01.05 Surgical and Clinical Outcomes With Neoadjuvant Atezolizumab in Resectable Stage IB–IIIB NSCLC: LCMC3 Trial Primary Analysis
Ju-Whei Lee, J. Chaft, A. Nicholas, A. Patterson +26 more
202171 citations Open access
Semantic Scholar
A model combining clinical and genomic factors to predict response to PD-1/PD-L1 blockade in advanced urothelial carcinoma
A. Nassar, K. Mouw, Opeyemi A. Jegede, A. Shinagare +16 more
2019British Journal of Cancer70 citations Open access
Semantic Scholar
Plasma cell-free DNA variant analysis compared with methylated DNA analysis in renal cell carcinoma
Kathryn D. Lasseter, A. Nassar, L. Hamieh, J. Berchuck +12 more
2020Genetics in Medicine68 citations Open access
Semantic Scholar
Early Clinical Predictors of Autism Spectrum Disorder in Infants with Tuberous Sclerosis Complex: Results from the EPISTOP Study
R. Moavero, A. Benvenuto, Leonardo Emberti Gialloreti, M. Siracusano +20 more
2019Journal of Clinical Medicine66 citations Open access
Semantic Scholar
Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non–Muscle-Invasive Bladder Cancer
J. Bellmunt, Jaegil Kim, B. Reardon, J. Perera-Bel +17 more
2020Cancer Research65 citations Open access
Semantic Scholar
Mammalian SWI/SNF complex genomic alterations and immune checkpoint blockade in solid tumors
S. A. Alaiwi, A. Nassar, Wan-Ling Xie, Z. Bakouny +28 more
2020Cancer immunology research65 citations Open access
Semantic Scholar
Midkine expression by stem-like tumor cells drives persistence to mTOR inhibition and an immune-suppressive microenvironment
Yan Tang, D. Kwiatkowski, E. Henske
2022Nature Communications57 citations Open access
Semantic Scholar
Phase II clinical trial of everolimus in a pan-cancer cohort of patients with mTOR pathway alterations
E. Adib, K. Klonowska, K. Giannikou, K. Do +15 more
2021Clinical Cancer Research50 citations Open access
Semantic Scholar
Synergistic antitumor activity of pan-PI3K inhibition and immune checkpoint blockade in bladder cancer
Shaoming Zhu, Ai-Hong Ma, Zheng Zhu, E. Adib +11 more
2021Journal for ImmunoTherapy of Cancer47 citations Open access
Semantic Scholar
Early epileptiform EEG activity in infants with tuberous sclerosis complex predicts epilepsy and neurodevelopmental outcomes
J. De Ridder, B. Verhelle, J. Vervisch, K. Lemmens +21 more
2021Epilepsia40 citations Open access
Semantic Scholar
OA06.06 Clinical/Biomarker Data for Neoadjuvant Atezolizumab in Resectable Stage IB-IIIB NSCLC: Primary Analysis in the LCMC3 Study
D. Carbone, Ju-Whei Lee, M. Kris, I. Wistuba +27 more
202139 citations Open access
Semantic Scholar
Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin
P. Cheah, S. Prabhakar, D. Yellen, R. Beauchamp +13 more
2021Science Advances35 citations Open access
Semantic Scholar
Is autism driven by epilepsy in infants with Tuberous Sclerosis Complex?
R. Moavero, K. Kotulska, L. Lagae, A. Benvenuto +19 more
2020Annals of Clinical and Translational Neurology35 citations Open access
Semantic Scholar
Concurrent osimertinib plus gefitinib for first-line treatment of EGFR-mutated non-small cell lung cancer (NSCLC).
J. Rotow, D. Costa, C. Paweletz, M. Awad +14 more
202034 citations
Semantic Scholar
Abstract CT006: First-in-class, first-in-human phase 1 trial of VT3989, an inhibitor of yes-associated protein (YAP)/transcriptional enhancer activator domain (TEAD), in patients (pts) with advanced solid tumors enriched for malignant mesothelioma and other tumors with neurofibromatosis 2 (NF2) muta
T. Yap, D. Kwiatkowski, J. Desai, I. Dagogo-Jack +7 more
2023Cancer Research33 citations
Semantic Scholar
Prediction of Neurodevelopment in Infants With Tuberous Sclerosis Complex Using Early EEG Characteristics
J. De Ridder, M. Lavanga, B. Verhelle, J. Vervisch +23 more
2020Frontiers in Neurology31 citations Open access
Semantic Scholar
Comprehensive genetic and phenotype analysis of 95 individuals with mosaic tuberous sclerosis complex.
K. Klonowska, K. Giannikou, J. Grevelink, Barbara Boeszoermenyi +10 more
2023American Journal of Human Genetics30 citations Open access
Semantic Scholar
Surgical results of the Lung Cancer Mutation Consortium 3 trial: A phase II multicenter single-arm study to investigate the efficacy and safety of atezolizumab as neoadjuvant therapy in patients with stages IB-select IIIB resectable non–small cell lung cancer
V. Rusch, A. Nicholas, G. Patterson, Salama N. Waqar +25 more
2022Journal of Thoracic and Cardiovascular Surgery30 citations Open access
Semantic Scholar
RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics.
R. Bekele, A. Samant, A. Nassar, J. So +14 more
2021Journal of Clinical Investigation30 citations Open access
Semantic Scholar
Myelin Pathology Beyond White Matter in Tuberous Sclerosis Complex (TSC) Cortical Tubers
A. Mühlebner, J. van Scheppingen, Andrew de Neef, A. Bongaarts +20 more
2020Journal of Neuropathology and Experimental Neurology29 citations Open access
Semantic Scholar
Epigenomic charting and functional annotation of risk loci in renal cell carcinoma
A. Nassar, Sarah Abou Alaiwi, Sylvan C. Baca, E. Adib +32 more
2023Nature Communications28 citations Open access
Semantic Scholar
A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo
J. R. Hernandez, X. Wang, M. Vázquez-Segoviano, M. López-Marfil +12 more
2021Nature Communications28 citations Open access
Semantic Scholar
CDH1 germline variants are enriched in patients with colorectal cancer, gastric cancer, and breast cancer
E. Adib, T. El Zarif, A. Nassar, E. Akl +9 more
2021British Journal of Cancer26 citations Open access
Semantic Scholar
1O Dynamic circulating tumour DNA (ctDNA) response to neoadjuvant (NA) atezolizumab (atezo) and surgery (surg) and association with outcomes in patients (pts) with NSCLC
M. Kris, J. Grindheim, J. Chaft, J. Lee +14 more
2021Annals of Oncology26 citations Open access
Semantic Scholar
Trans-ethnic variation in germline variants of patients with renal cell carcinoma.
Sarah Abou Alaiwi, A. Nassar, E. Adib, S. Groha +15 more
2021Cell Reports26 citations Open access
Semantic Scholar
Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile
K. Giannikou, Zachary Zhu, Jaegil Kim, K. Winden +26 more
2020Modern Pathology24 citations Open access
Semantic Scholar
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway
Jian Carrot-Zhang, Xiao-Tong Yao, S. Devarakonda, Aditya Deshpande +78 more
2021Cell Reports23 citations Open access
Semantic Scholar
Mosaicism in Tumor Suppressor Gene Syndromes: Prevalence, Diagnostic Strategies, and Transmission Risk.
Jillian L. Chen, David T. Miller, Laura S. Schmidt, D. Malkin +4 more
2022Annual review of genomics and human genetics (Print)22 citations Open access
Semantic Scholar
Association of Early MRI Characteristics With Subsequent Epilepsy and Neurodevelopmental Outcomes in Children With Tuberous Sclerosis Complex
H. Hulshof, H. Kuijf, K. Kotulska, P. Curatolo +21 more
2022Neurology21 citations Open access
Semantic Scholar
FGFR2/3 genomic alterations and response to Enfortumab Vedotin in metastatic urothelial carcinoma
E. Adib, T. El Zarif, R. Jain, W. P. Skelton +9 more
2021BJUI Compass17 citations Open access
Semantic Scholar
Long-term follow-up for duration of response (DoR) after weekly nab-sirolimus in patients with advanced malignant perivascular epithelioid cell tumors (PEComa): Results from a registrational open-label phase II trial, AMPECT.
A. Wagner, V. Ravi, R. Riedel, K. Ganjoo +13 more
202016 citations
Semantic Scholar
Features of tumor-microenvironment images predict targeted therapy survival benefit in patients with EGFR-mutant lung cancer
Shidan Wang, Ruichen Rong, Dong-Han M. Yang, J. Fujimoto +16 more
2023Journal of Clinical Investigation15 citations Open access
Semantic Scholar
LCMC LEADER neoadjuvant screening trial: LCMC4 evaluation of actionable drivers in early-stage lung cancers.
B. Sepesi, David R. Jones, B. Meyers, J. Chaft +14 more
2022Journal of Clinical Oncology15 citations
Semantic Scholar
MITF is a driver oncogene and potential therapeutic target in kidney angiomyolipoma tumors through transcriptional regulation of CYR61
Mahsa Zarei, K. Giannikou, H. Du, Heng-Jia Liu +7 more
2020Oncogene15 citations Open access
Semantic Scholar
miRNAs and isomiRs: Serum-Based Biomarkers for the Development of Intellectual Disability and Autism Spectrum Disorder in Tuberous Sclerosis Complex
Mirte Scheper, Alessia Romagnolo, Z. M. Besharat, A. Iyer +25 more
2022Biomedicines14 citations Open access
Semantic Scholar
Lymphangioleiomyomatosis (LAM) Cell Atlas
Yina Du, M. Guo, Yixin Wu, A. Wagner +12 more
2022Thorax13 citations
Semantic Scholar
Whole-genome characterization of lung adenocarcinomas lacking alterations in the RTK/RAS/RAF pathway
Jian Carrot-Zhang, Xiao-Tong Yao, S. Devarakonda, Aditya Deshpande +53 more
2021Cell Reports13 citations Open access
Semantic Scholar
Celecoxib in lymphangioleiomyomatosis: results of a phase I clinical trial
S. El-Chemaly, A. Taveira-Dasilva, Shefali Bagwe, K. Klonowska +10 more
2020European Respiratory Journal13 citations Open access
Semantic Scholar

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