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D. Carson · SciRah

Researcher profile · Semantic Scholar

D. Carson

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D. Carson — researcher profile on SciRah

h-index: 79
Works: 349
Citations: 23K

Most-cited papers

The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity
Toshiro Moroishi, Tomoko Hayashi, Wei-Wei Pan, Y. Fujita +4 more
2016Cell405 citations Open access
Semantic Scholar
Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer.
Fumi Sato-Kaneko, Shiyin Yao, Alast Ahmadi, Shannon S. Zhang +13 more
2017JCI Insight264 citations Open access
Semantic Scholar
Transcriptome Sequencing Reveals Potential Mechanism of Cryptic 3’ Splice Site Selection in SF3B1-mutated Cancers
Christopher M. DeBoever, E. Ghia, Peter J. Shepard, L. Rassenti +6 more
2015PLoS Comput. Biol.217 citations Open access
Semantic Scholar
Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells
Zhong-yuan Wang, Bo Li, Liang Zhou, Shu-Bin Yu +10 more
2016Proceedings of the National Academy of Sciences of the United States of America192 citations Open access
Semantic Scholar
Ovarian cancer stem cells express ROR1, which can be targeted for anti–cancer-stem-cell therapy
Su-Ping Zhang, Bing Cui, Hsien Lai, Grace Liu +9 more
2014Proceedings of the National Academy of Sciences of the United States of America185 citations Open access
Semantic Scholar
Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody
Su-Ping Zhang, Han Zhang, E. Ghia, Jia-Jia Huang +14 more
2019Proceedings of the National Academy of Sciences of the United States of America129 citations Open access
Semantic Scholar
The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells
Antonio Fernandez, Ian J. Huggins, Luca Perna, David A. Brafman +5 more
2014Proceedings of the National Academy of Sciences of the United States of America110 citations Open access
Semantic Scholar
Synthetic Toll-Like Receptor 4 (TLR4) and TLR7 Ligands as Influenza Virus Vaccine Adjuvants Induce Rapid, Sustained, and Broadly Protective Responses
P. Goff, Tomoko Hayashi, Luis Martínez-Gil, M. Corr +13 more
2015Journal of Virology109 citations Open access
Semantic Scholar
Pre-clinical specificity and safety of UC-961, a first-in-class monoclonal antibody targeting ROR1
M. Choi, G. Widhopf, Christina N. Wu, Bing Cui +7 more
2015Clinical Lymphoma, Myeloma & Leukemia108 citations Open access
Semantic Scholar
TLR4-dependent activation of dendritic cells by an HMGB1-derived peptide adjuvant
Rebecca Saenz, Diahnn Futalan, Lien Leutenez, Fien Eekhout +10 more
2014Journal of Translational Medicine102 citations Open access
Semantic Scholar
Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Anti-Tumor Immunity in a Murine Pancreatic Cancer Model
J. S. Shankara Narayanan, P. Ray, Tomoko Hayashi, T. Whisenant +5 more
2019Cancer immunology research88 citations Open access
Semantic Scholar
Identification of Substituted Pyrimido[5,4-b]indoles as Selective Toll-Like Receptor 4 Ligands
Michael Chan, Tomoko Hayashi, Richard D. Mathewson, A. Nour +11 more
2013Journal of Medicinal Chemistry84 citations Open access
Semantic Scholar
Systematic transcriptome analysis reveals tumor-specific isoforms for ovarian cancer diagnosis and therapy
Christian L. Barrett, Christopher M. DeBoever, K. Jepsen, Cheryl C. Saenz +2 more
2015Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to Polysaccharides.
H. Shinchi, B. Crain, Shiyin Yao, Michael Chan +6 more
2015Bioconjugate chemistry49 citations
Semantic Scholar
Targeting the Wnt/beta-catenin pathway with the antifungal agent ciclopirox olamine in a murine myeloma model.
Y. Kim, Matthias Schmidt, T. Endo, De-Sheng Lu +2 more
2011In Vivo47 citations
Semantic Scholar
NOTCH1 Signaling Promotes Human T-Cell Acute Lymphoblastic Leukemia Initiating Cell Regeneration in Supportive Niches
Wenxue Ma, A. Gutierrez, D. Goff, I. Geron +16 more
2012PLoS ONE43 citations Open access
Semantic Scholar
Salinomycin exerts anti‐colorectal cancer activity by targeting the β‐catenin/T‐cell factor complex
Zhong-yuan Wang, Liang Zhou, Yan-Peng Xiong, Shu-Bin Yu +14 more
2019British Journal of Pharmacology42 citations Open access
Semantic Scholar
Oral administration of PEGylated TLR7 ligand ameliorates alcohol-associated liver disease via the induction of IL-22
Qing-Lan Wang, S. Y. Kim, H. Matsushita, Zhijun Wang +13 more
2020Proceedings of the National Academy of Sciences of the United States of America35 citations Open access
Semantic Scholar
Tumor promoter TPA activates Wnt/β-catenin signaling in a casein kinase 1-dependent manner
Zi-Jie Su, Jiaxing Song, Zhong-yuan Wang, Liang Zhou +9 more
2018Proceedings of the National Academy of Sciences of the United States of America35 citations Open access
Semantic Scholar
Biased estimates of clonal evolution and subclonal heterogeneity can arise from PCR duplicates in deep sequencing experiments
Erin N. Smith, K. Jepsen, Mahdieh Khosroheidari, L. Rassenti +6 more
2014Genome Biology35 citations Open access
Semantic Scholar
Delivery of Immunotherapeutic Nanoparticles to Tumors via Enzyme‐Directed Assembly
Claudia Battistella, Cassandra E. Callmann, M. Thompson, Shiyin Yao +4 more
2019Advanced Healthcare Materials32 citations
Semantic Scholar
A FZD7-specific antibody-drug conjugate induces ovarian tumor regression in preclinical models
Myan Do, Christina C. N. Wu, Pooja R. Sonavane, Edwin F. Juarez +8 more
2021Molecular Cancer Therapeutics30 citations Open access
Semantic Scholar
A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity
Fumi Sato-Kaneko, Shiyin Yao, Fitzgerald S. Lao, J. Shpigelman +12 more
2020Frontiers in Immunology29 citations Open access
Semantic Scholar
Synthetic Toll-Like Receptor 4 (TLR4) and TLR7 Ligands Work Additively via MyD88 To Induce Protective Antiviral Immunity in Mice
P. Goff, Tomoko Hayashi, Wenqian He, Shiyin Yao +9 more
2017Journal of Virology28 citations Open access
Semantic Scholar
Generation and Application of a Reporter Cell Line for the Quantitative Screen of Extracellular Vesicle Release
J. Shpigelman, Fitzgerald S. Lao, Shiyin Yao, Chen-Yang Li +10 more
2021Frontiers in Pharmacology27 citations Open access
Semantic Scholar
Gold nanoparticles co-immobilized with small molecule toll-like receptor 7 ligand and α-mannose as adjuvants.
H. Shinchi, Toru Yamaguchi, Toshiro Moroishi, Masaharu Yuki +5 more
2019Bioconjugate chemistry26 citations
Semantic Scholar
Structure-Activity Relationship Studies of Pyrimido[5,4-b]indoles as Selective Toll-Like Receptor 4 Ligands.
Michael Chan, Yuhei Kakitsubata, Tomoko Hayashi, Alast Ahmadi +10 more
2017Journal of Medicinal Chemistry26 citations Open access
Semantic Scholar
Discovery of substituted 4-aminoquinazolines as selective Toll-like receptor 4 ligands
A. Nour, Tomoko Hayashi, Michael Chan, Shiyin Yao +10 more
2014Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
Treatment of Autoimmune Inflammation by a TLR7 Ligand Regulating the Innate Immune System
Tomoko Hayashi, Shiyin Yao, B. Crain, Michael Chan +7 more
2012PLoS ONE25 citations Open access
Semantic Scholar
In vivo efficacy of the diuretic agent ethacrynic acid against multiple myeloma.
Y. Kim, Sanna-Marie Gast, T. Endo, De-Sheng Lu +2 more
2012Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis25 citations
Semantic Scholar
Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist
T. Hosoya, Fumi Sato-Kaneko, Alast Ahmadi, Shiyin Yao +5 more
2018Proceedings of the National Academy of Sciences of the United States of America24 citations Open access
Semantic Scholar
Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes
Tomoko Hayashi, Shiyin Yao, B. Crain, Victor J. Promessi +6 more
2015PLoS ONE24 citations Open access
Semantic Scholar
Cutting Edge: Nitrogen Bisphosphonate-Induced Inflammation Is Dependent upon Mast Cells and IL-1
J. Norton, Tomoko Hayashi, B. Crain, John S. Cho +3 more
2012Journal of Immunology24 citations Open access
Semantic Scholar
Additive melanoma suppression with intralesional phospholipid conjugated TLR7 agonists and systemic IL-2
Tomoko Hayashi, Michael Chan, J. Norton, Christina N. Wu +6 more
2011Melanoma research24 citations Open access
Semantic Scholar
Increased in vivo efficacy of lenalidomide and thalidomide by addition of ethacrynic acid.
Matthias Schmidt, Y. Kim, Sanna-Marie Gast, T. Endo +3 more
2011In Vivo24 citations
Semantic Scholar
Influencing the Wnt signaling pathway in multiple myeloma.
Y. Kim, G. Reifenberger, De-Sheng Lu, T. Endo +5 more
2011Anticancer Research23 citations
Semantic Scholar
Innate immune protection against infectious diseases by pulmonary administration of a phospholipid conjugated TLR7 ligand
Christina N. Wu, B. Crain, Shiyin Yao, M. Sabet +10 more
2013Journal of Innate Immunity22 citations Open access
Semantic Scholar
Synthesis and biological evaluation of 2′,4′- and 3′,4′-bridged nucleoside analogues
K. Nicolaou, S. Ellery, F. Rivas, Karen Saye +9 more
2011Bioorganic & Medicinal Chemistry22 citations Open access
Semantic Scholar
Cell-penetrating peptide CGKRK mediates efficient and widespread targeting of bladder mucosa following focal injury
James I. Griffin, S. Cheng, Tomoko Hayashi, D. Carson +3 more
2017Nanomedicine : nanotechnology, biology, and medicine20 citations Open access
Semantic Scholar
Novel Synthetic Toll-Like Receptor 4/MD2 Ligands Attenuate Sterile Inflammation
Tomoko Hayashi, B. Crain, Shiyin Yao, C. Caneda +4 more
2014Journal of Pharmacology and Experimental Therapeutics19 citations Open access
Semantic Scholar
Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells
D. Gumber, Myan Do, Neya Suresh Kumar, Pooja R. Sonavane +6 more
2020bioRxiv18 citations Open access
Semantic Scholar
Identification of Biologically Active Pyrimido[5,4-b]indoles That Prolong NF-κB Activation without Intrinsic Activity
Michael Chan, Alast Ahmadi, Shiyin Yao, Fumi Sato-Kaneko +8 more
2017ACS Combinatorial Science18 citations Open access
Semantic Scholar
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two
C. Ager, M. Reilley, C. Nicholas, Todd Bartkowiak +496 more
2016Journal for ImmunoTherapy of Cancer18 citations Open access
Semantic Scholar
Analysis of High Throughput Screening Assays using Cluster Enrichment
Min-Ya Pu, Tomoko Hayashi, H. Cottam, J. Mulvaney +4 more
2012Statistics in Medicine16 citations Open access
Semantic Scholar
Conjugation of a Small Molecule TLR7 Agonist to Silica Nanoshells Enhances Adjuvant Activity.
Ching‐Hsin Huang, Natalie Mendez, O. Echeagaray, Joi Weeks +7 more
2019ACS Applied Materials and Interfaces14 citations
Semantic Scholar
Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators.
Nikunj M. Shukla, Michael Chan, Tomoko Hayashi, D. Carson +1 more
2018ACS Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Whole Transcriptome Sequencing Enables Discovery and Analysis of Viruses in Archived Primary Central Nervous System Lymphomas
Christopher M. DeBoever, E. Reid, Erin N. Smith, Xiaoyun Wang +6 more
2013PLoS ONE13 citations Open access
Semantic Scholar
Immunostimulatory TLR7 agonist-nanoparticles together with checkpoint blockade for effective cancer immunotherapy
Ching‐Hsin Huang, Natalie Mendez, O. Echeagaray, Joi Weeks +8 more
2020Advances in Therapy12 citations Open access
Semantic Scholar
Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy
Fumi Sato-Kaneko, Xiaodong Wang, Shiyin Yao, T. Hosoya +9 more
2018BioMed Research International12 citations Open access
Semantic Scholar
Cirmtuzumab Vedotin (UC-961ADC3), An Anti-ROR1-Monomethyl Auristatin E Antibody-Drug Conjugate, Is a Potential Treatment For ROR1-Positive Leukemia and Solid Tumors
Bing Cui, G. Widhopf, C. Prussak, Christina C. N. Wu +6 more
201312 citations
Semantic Scholar

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