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I. Manfield · SciRah

Researcher profile · Semantic Scholar

I. Manfield

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I. Manfield — researcher profile on SciRah

h-index: 26
Works: 51
Citations: 2,667

Most-cited papers

Mutations involved in Aicardi-Goutières syndrome implicate SAMHD1 as regulator of the innate immune response
G. Rice, J. Bond, A. Asipu, Rebecca L. Brunette +47 more
2009Nature Genetics715 citations Open access
Semantic Scholar
Arabidopsis Co-expression Tool (ACT): web server tools for microarray-based gene expression analysis
I. Manfield, Chih-Hung Jen, J. Pinney, I. Michalopoulos +3 more
2006Nucleic Acids Res.176 citations Open access
Semantic Scholar
Affimer proteins are versatile and renewable affinity reagents
C. Tiede, R. Bedford, Sophie J. Heseltine, Gina A. Smith +42 more
2017eLife150 citations Open access
Semantic Scholar
Novel cell wall architecture of isoxaben-habituated Arabidopsis suspension-cultured cells: global transcript profiling and cellular analysis.
I. Manfield, C. Orfila, Lesley McCartney, J. Harholt +6 more
2004The Plant Journal149 citations Open access
Semantic Scholar
Arabidopsis thaliana GATA factors: organisation, expression and DNA-binding characteristics
G. Teakle, I. Manfield, J. F. Graham, P. Gilmartin
2002Plant Molecular Biology127 citations
Semantic Scholar
Conservation, Convergence, and Divergence of Light-Responsive, Circadian-Regulated, and Tissue-Specific Expression Patterns during Evolution of the Arabidopsis GATA Gene Family1[W][OA]
I. Manfield, P. Devlin, Chih-Hung Jen, D. Westhead +1 more
2006Plant Physiology115 citations Open access
Semantic Scholar
Direct Evidence for Packaging Signal-Mediated Assembly of Bacteriophage MS2
Ó. Rolfsson, Stefani Middleton, I. Manfield, Simon J. White +8 more
2016Journal of Molecular Biology100 citations Open access
Semantic Scholar
Cooperative tandem binding of met repressor of Escherichia coli
S. Phillips, I. Manfield, Isobel D. Parsons, B. E. Davidson +6 more
1989Nature91 citations
Semantic Scholar
Staphylococcal biofilm-forming protein has a contiguous rod-like structure
D. Gruszka, J. Wojdyla, R. Bingham, J. Turkenburg +7 more
2012Proceedings of the National Academy of Sciences of the United States of America86 citations Open access
Semantic Scholar
The Arabidopsis co-expression tool (ACT): a WWW-based tool and database for microarray-based gene expression analysis.
Chih-Hung Jen, I. Manfield, I. Michalopoulos, J. Pinney +3 more
2006The Plant Journal81 citations
Semantic Scholar
Tuning the rate of aggregation of hIAPP into amyloid using small-molecule modulators of assembly
Yong Xu, Roberto Maya-Martinez, N. Guthertz, George R. Heath +5 more
2022Nature Communications65 citations Open access
Semantic Scholar
Epitope detection chromatography: a method to dissect the structural heterogeneity and inter-connections of plant cell-wall matrix glycans.
Valérie Cornuault, I. Manfield, M. Ralet, J. Knox
2014The Plant Journal64 citations Open access
Semantic Scholar
Analysis of Seaweed Extract-induced Transcriptome Leads to Identification of a Negative Regulator of Salt Tolerance in Arabidopsis
M. Jithesh, O. Wally, I. Manfield, A. Critchley +2 more
201259 citations Open access
Semantic Scholar
From gene expression to gene regulatory networks in Arabidopsis thaliana
C. Needham, I. Manfield, A. Bulpitt, P. Gilmartin +1 more
2009BMC Systems Biology50 citations Open access
Semantic Scholar
AtSPX1 affects the AtPHR1–DNA-binding equilibrium by binding monomeric AtPHR1 in solution
Wan-Jun Qi, I. Manfield, S. Muench, A. Baker
2017Biochemical Journal49 citations Open access
Semantic Scholar
Bacteriophage MS2 genomic RNA encodes an assembly instruction manual for its capsid
P. Stockley, Simon J. White, E. Dykeman, I. Manfield +10 more
2016Bacteriophage48 citations Open access
Semantic Scholar
Mutations in spliceosomal genes PPIL1 and PRP17 cause neurodegenerative pontocerebellar hypoplasia with microcephaly
Guoliang Chai, A. Webb, Chen Li, D. Antaki +33 more
2020Neuron47 citations Open access
Semantic Scholar
Transcript analysis reveals an extended regulon and the importance of protein-protein co-operativity for the Escherichia coli methionine repressor.
F. Marincs, I. Manfield, J. Stead, Kenneth J. McDowall +1 more
2006Biochemical Journal45 citations Open access
Semantic Scholar
Multi-scale spatial heterogeneity of pectic rhamnogalacturonan I (RG–I) structural features in tobacco seed endosperm cell walls
Kieran J. D. Lee, Valérie Cornuault, I. Manfield, M. Ralet +1 more
2013The Plant Journal40 citations Open access
Semantic Scholar
Molecular characterization of DNA sequences from the Primula vulgaris S-locus.
I. Manfield, Vassily K. Pavlov, Jin-Hong Li, Holly E. Cook +2 more
2005Journal of Experimental Botany38 citations Open access
Semantic Scholar
The effects of irradiation on the biological and biomechanical properties of an acellular porcine superflexor tendon graft for cruciate ligament repair
J. Edwards, A. Herbert, G. Jones, I. Manfield +2 more
2016Journal of Biomedical Materials Research. Part B - Applied biomaterials36 citations Open access
Semantic Scholar
Tenascin C upregulates interleukin-6 expression in human cardiac myofibroblasts via toll-like receptor 4.
A. Maqbool, Emma J. Spary, I. Manfield, M. Ruhmann +6 more
2016World Journal of Cardiology34 citations Open access
Semantic Scholar
Application of isothermal titration calorimetry in evaluation of protein–nanoparticle interactions
E. Omanović-Mikličanin, I. Manfield, T. Wilkins
2016Journal of Thermal Analysis and Calorimetry32 citations
Semantic Scholar
Arabidopsis PEX19 is a dimeric protein that binds the peroxin PEX10
Dawn A Hadden, B. Phillipson, K. Johnston, Laura-Anne Brown +4 more
2006Molecular membrane biology31 citations Open access
Semantic Scholar
Probing met represser–operator recognition in solution
Yi-Yuan He, T. Mcnally, I. Manfield, O. Navratil +4 more
1992Nature30 citations
Semantic Scholar
Re-engineering of the PAM1 phage display monoclonal antibody to produce a soluble, versatile anti-homogalacturonan scFv
I. Manfield, Adriana J. Bernal, Isabel E. Moller, Lesley McCartney +3 more
200527 citations Open access
Semantic Scholar
A missense variant in specificity protein 6 (SP6) is associated with amelogenesis imperfecta
Claire E. L. Smith, L. Whitehouse, J. Poulter, Laura Wilkinson Hewitt +7 more
2020Human Molecular Genetics26 citations Open access
Semantic Scholar
Affimer proteins as a tool to modulate fibrinolysis, stabilize the blood clot, and reduce bleeding complications.
Katherine J. Kearney, N. Pechlivani, R. King, C. Tiede +12 more
2019Blood26 citations Open access
Semantic Scholar
Defining the remarkable structural malleability of a bacterial surface protein Rib domain implicated in infection
F. Whelan, Aleix Lafita, S. Griffiths, R. E. M. Cooper +7 more
2019Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
Structural and functional studies of an intermediate on the pathway to operator binding by Escherichia coli MetJ.
Yi-Yuan He, C. Garvie, S. Elworthy, I. Manfield +4 more
2002Journal of Molecular Biology18 citations
Semantic Scholar
The S locus-linked Primula homeotic mutant sepaloid shows characteristics of a B-function mutant but does not result from mutation in a B-function gene.
Jin-Hong Li, M. Webster, B. Dudás, Holly E. Cook +3 more
2008The Plant Journal17 citations Open access
Semantic Scholar
The DNA-binding domain of the gene regulatory protein AreA extends beyond the minimal zinc-finger region conserved between GATA proteins.
I. Manfield, L. Reynolds, John R. Gittins, G. Kneale
2000Biochimica et Biophysica Acta12 citations
Semantic Scholar
The Met Repressor‐Operator Complex: DNA Recognition by β‐Strands a
W. Somers, J. Rafferty, K. Phillips, S. Strathdee +8 more
199412 citations
Semantic Scholar
Mutations of the domain forming the dimeric interface of the ArdA protein affect dimerization and antimodification activity but not antirestriction activity
G. A. Roberts, Kai Chen, Edward K M Bower, J. Mądrzak +7 more
2013The FEBS Journal10 citations Open access
Semantic Scholar
A bovine antibody possessing an ultralong complementarity-determining region CDRH3 targets a highly conserved epitope in sarbecovirus spike proteins
Matthew J. Burke, James N. F. Scott, T. Minshull, Zeqian Gao +5 more
2022Journal of Biological Chemistry7 citations Open access
Semantic Scholar
A Comparative Assessment Study of Known Small-molecule GPVI Modulators.
Holly Foster, Clare L Wilson, J. Gauer, Rui-Gang Xu +7 more
2022ACS Medicinal Chemistry Letters5 citations Open access
Semantic Scholar
E. coli Met Repressor: DNA Recognition by β-Strands
S. Phillips, C. Boys, Y.-Y. He, I. Manfield +9 more
19935 citations
Semantic Scholar
A biaryl peptide crosslink in a MetJ peptide model confers cooperative, nonspecific binding to DNA that ablates both repressor binding and in vitro transcription.
Joshua C. Yoburn, S. Deb, I. Manfield, P. Stockley +1 more
2003Bioorganic & Medicinal Chemistry4 citations
Semantic Scholar
Structural and functional characterisation of the DNA binding domain of the Aspergillus nidulans gene regulatory protein AreA.
A. Chant, X. Provatopoulou, I. Manfield, G. Kneale
2003Biochimica et Biophysica Acta4 citations
Semantic Scholar
A fuzzy encounter complex precedes formation of the fully-engaged TIR1-Aux/IAA auxin co-receptor system
Sigurd Ramans-Harborough, A. Kalverda, G. Thompson, M. Kieffer +8 more
2019bioRxiv3 citations Open access
Semantic Scholar
Ethylation interference.
I. Manfield, P. Stockley
1994Methods in molecular biology3 citations
Semantic Scholar
The Met repressor-operator complex: DNA recognition by beta-strands.
W. Somers, J. Rafferty, K. Phillips, S. Strathdee +6 more
1994Annals of the New York Academy of Sciences3 citations
Semantic Scholar
Dysregulation of Hepatitis B Virus Nucleocapsid Assembly with RNA-directed Small Ligands
N. Patel, Fardokht A. Abulwerdi, F. Fatehi, I. Manfield +4 more
2021bioRxiv2 citations Open access
Semantic Scholar
Ethylation interference footprinting of DNA-protein complexes.
I. Manfield, P. Stockley
2009Methods in molecular biology2 citations
Semantic Scholar
Irradiation of acellular porcine superflexor tendons.
J. Edwards, A. Herbert, I. Manfield, J. Fisher +1 more
20151 citations
Semantic Scholar
A novel method for the purification of recombinant subunit I of theDolichos biflorus seed lectin
S. Deb, I. Manfield, B. Carpenter
1997Molecular Biotechnology1 citations
Semantic Scholar
Dataset of high-throughput ligand screening against the RNA Packaging Signals regulating Hepatitis B Virus nucleocapsid formation
Fardokht A. Abulwerdi, F. Fatehi, I. Manfield, S. Le Grice +4 more
2022Data in Brief0 citations Open access
Semantic Scholar
Direct evidence for a RNA packaging signal-mediated virus assembly mechanism
N. Patel, Simon J. White, Ó. Rolfsson, I. Manfield +5 more
20160 citations
Semantic Scholar
Interactive Properties of A-Band Titin
Sarika Khasnis, M. Walker, G. Spedalieri, G. N. Khan +3 more
20140 citations Open access
Semantic Scholar
Modeling Poly-Lysine Interactions with Mutant and Wild Type Cardiac Myosin Subfragment-2
A. Unger, N. Hamdani, Luitgard Nagel-Steger, M. Walker +4 more
20140 citations
Semantic Scholar

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