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F. V. van Kuppeveld · SciRah

Researcher profile · Semantic Scholar

F. V. van Kuppeveld

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F. V. van Kuppeveld — researcher profile on SciRah

h-index: 80
Works: 359
Citations: 20K

Most-cited papers

A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies
Chunyan Wang, Rien van Haperen, J. Gutiérrez-Álvarez, Wen-Tao Li +14 more
2021Nature Communications185 citations Open access
Semantic Scholar
A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays
Yan Ni, B. Rosier, Eva A. van Aalen, Eva T. L. Hanckmann +12 more
2021Nature Communications93 citations Open access
Semantic Scholar
SARS-CoV-2 mucosal antibody development and persistence and their relation to viral load and COVID-19 symptoms
Janeri Fröberg, J. Gillard, R. Philipsen, K. Lanke +15 more
2021Nature Communications82 citations Open access
Semantic Scholar
Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions
Meng-Ying Liu, Liane Z X Huang, Anthony A. Smits, C. Büll +5 more
2022Nature Communications81 citations Open access
Semantic Scholar
Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity
Yifei Lang, Wen-Tao Li, Zeshi Li, Danielle Koerhuis +8 more
2020Proceedings of the National Academy of Sciences of the United States of America79 citations Open access
Semantic Scholar
Sialoglycan binding triggers spike opening in a human coronavirus
M. Pronker, Robert Creutznacher, I. Drulyte, R. J. Hulswit +9 more
2023bioRxiv69 citations Open access
Semantic Scholar
Development of a SARS-CoV-2 Total Antibody Assay and the Dynamics of Antibody Response over Time in Hospitalized and Nonhospitalized Patients with COVID-19
E. Vogelzang, F. Loeff, N. Derksen, S. Kruithof +23 more
2020Journal of Immunology68 citations Open access
Semantic Scholar
Respiratory mucus as a virus-host range determinant
Louisa Elizabeth Wallace, Mengying Liu, F. V. van Kuppeveld, E. de Vries +1 more
2021Trends in Microbiology62 citations Open access
Semantic Scholar
Serologic Screening of Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Cats and Dogs during First Coronavirus Disease Wave, the Netherlands
Shan Zhao, N. Schuurman, Wen-Tao Li, Chunyan Wang +6 more
2021Emerging Infectious Diseases59 citations Open access
Semantic Scholar
A small-molecule SARS-CoV-2 inhibitor targeting the membrane protein
E. Van Damme, Pravien Abeywickrema, Yan-Ting Yin, Jie-Xiong Xie +45 more
2025Nature58 citations Open access
Semantic Scholar
Second sialic acid‐binding site of influenza A virus neuraminidase: binding receptors for efficient release
Wenjuan Du, E. de Vries, F. V. van Kuppeveld, M. Matrosovich +1 more
2020The FEBS Journal53 citations Open access
Semantic Scholar
Structural insights into the cross-neutralization of SARS-CoV and SARS-CoV-2 by the human monoclonal antibody 47D11
J. Fedry, Daniel L. Hurdiss, Chunyan Wang, Wen-Tao Li +7 more
2021Science Advances50 citations Open access
Semantic Scholar
The trispecific DARPin ensovibep inhibits diverse SARS-CoV-2 variants
S. Rothenberger, Daniel L. Hurdiss, M. Walser, F. Malvezzi +64 more
2022Nature Biotechnology48 citations Open access
Semantic Scholar
Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes
Chunyan Wang, E. Hesketh, Tatiana M. Shamorkina, Wen-Tao Li +11 more
2022Nature Communications48 citations Open access
Semantic Scholar
An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern
Wenjuan Du, Daniel L. Hurdiss, D. Drabek, A. Mykytyn +23 more
2022bioRxiv47 citations Open access
Semantic Scholar
The activation of the adaptor protein STING depends on its interactions with the phospholipid PI4P
R. Luteijn, Sypke R. van Terwisga, Jill E. Ver Eecke, Liberty Onia +5 more
2024Science Signaling39 citations Open access
Semantic Scholar
A coronavirus assembly inhibitor that targets the viral membrane protein
M. Laporte, Dirk Jochmans, D. Bardiot, L. Desmarets +49 more
2025Nature38 citations Open access
Semantic Scholar
Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex
Daniel L. Hurdiss, Priscila El Kazzi, Lisa Bauer, N. Papageorgiou +12 more
2022Science Advances35 citations Open access
Semantic Scholar
The encephalomyocarditis virus Leader promotes the release of virions inside extracellular vesicles via the induction of secretory autophagy
S. G. van der Grein, Kyra A. Y. Defourny, H. Rabouw, S. Goerdayal +5 more
2021Nature Communications35 citations Open access
Semantic Scholar
MFSD6 is an entry receptor for enterovirus D68
Lauren Varanese, Lily Xu, Christine E. Peters, G. Pintilie +15 more
2025Nature33 citations Open access
Semantic Scholar
H3N2 influenza A virus gradually adapts to human-type receptor binding and entry specificity after the start of the 1968 pandemic
Meng-Ying Liu, A. S. Bakker, Y. Narimatsu, F. V. van Kuppeveld +3 more
2023Proceedings of the National Academy of Sciences of the United States of America29 citations Open access
Semantic Scholar
Enterovirus D68 Infection in Human Primary Airway and Brain Organoids: No Additional Role for Heparan Sulfate Binding for Neurotropism
Adithya Sridhar, Josse A. Depla, Lance A. Mulder, Eveliina Karelehto +8 more
2022Microbiology spectrum29 citations Open access
Semantic Scholar
Antiviral responses are shaped by heterogeneity in viral replication dynamics
L. J. Bruurs, M. Müller, J. Schipper, H. Rabouw +3 more
2023Nature Microbiology28 citations Open access
Semantic Scholar
Analysis of the Evolution of Pandemic Influenza A(H1N1) Virus Neuraminidase Reveals Entanglement of Different Phenotypic Characteristics
M. Dai, Wenjuan Du, Carles Martínez-Romero, Tim Leenders +7 more
2021mBio24 citations Open access
Semantic Scholar
Serological Screening of Influenza A Virus Antibodies in Cats and Dogs Indicates Frequent Infection with Different Subtypes
Shan Zhao, N. Schuurman, Malte Tieke, Berit Quist +4 more
2020Journal of Clinical Microbiology24 citations Open access
Semantic Scholar
Bithiazole Inhibitors of Phosphatidylinositol 4‐Kinase (PI4KIIIβ) as Broad‐Spectrum Antivirals Blocking the Replication of SARS‐CoV‐2, Zika Virus, and Human Rhinoviruses
Maria Grazia Martina, I. Vicenti, Lisa Bauer, Emmanuele Crespan +12 more
2021ChemMedChem23 citations Open access
Semantic Scholar
An alphavirus replicon-based vaccine expressing a stabilized Spike antigen induces protective immunity and prevents transmission of SARS-CoV-2 between cats
M. Langereis, I. Albulescu, Judith Stammen-Vogelzangs, Morindy Lambregts +15 more
2021npj Vaccines22 citations Open access
Semantic Scholar
Nanoparticle display of neuraminidase elicits enhanced antibody responses and protection against influenza A virus challenge
M. N. Pascha, M. Ballegeer, M. Roelofs, L. Meuris +7 more
2024npj Vaccines20 citations Open access
Semantic Scholar
Safety concern of recombination between self-amplifying mRNA vaccines and viruses is mitigated in vivo
Tessy A. H. Hick, C. Geertsema, Wilson Nguyen, Linda van Oosten +11 more
2024Molecular Therapy20 citations Open access
Semantic Scholar
Neutralizing antibodies reveal cryptic vulnerabilities and interdomain crosstalk in the porcine deltacoronavirus spike protein
Wenjuan Du, Oliver J. Debski-Antoniak, D. Drabek, Rien van Haperen +7 more
2024Nature Communications19 citations Open access
Semantic Scholar
A broad-spectrum macrocyclic peptide inhibitor of the SARS-CoV-2 spike protein
V. Thijssen, Daniel L. Hurdiss, Oliver J. Debski-Antoniak, M. Spence +19 more
2023bioRxiv19 citations Open access
Semantic Scholar
Neuraminidase-dependent entry of influenza A virus is determined by hemagglutinin receptor-binding specificity
Louisa Elizabeth Wallace, E. de Vries, F. V. van Kuppeveld, C. D. de Haan
2023Journal of Virology18 citations Open access
Semantic Scholar
Highly potent anti-SARS-CoV-2 multi-DARPin therapeutic candidates
M. Walser, S. Rothenberger, Daniel L. Hurdiss, Anja Schlegel +50 more
2020bioRxiv18 citations Open access
Semantic Scholar
SARS-CoV-2 nucleocapsid protein inhibits the PKR-mediated integrated stress response through RNA-binding domain N2b
Chiara Aloise, J. Schipper, A. V. van Vliet, Judith Oymans +4 more
2023PLoS Pathogens17 citations Open access
Semantic Scholar
Gradual adaptation of animal influenza A viruses to human-type sialic acid receptors.
Meng-Ying Liu, F. V. van Kuppeveld, C. D. de Haan, E. de Vries
2023Current Opinion in Virology16 citations Open access
Semantic Scholar
Ensovibep, a novel trispecific DARPin candidate that protects against SARS-CoV-2 variants
S. Rothenberger, Daniel L. Hurdiss, M. Walser, F. Malvezzi +62 more
2021bioRxiv16 citations Open access
Semantic Scholar
Enterocytes, fibroblasts and myeloid cells synergize in anti-bacterial and anti-viral pathways with IL22 as the central cytokine
J. T. ten Klooster, M. Bol-Schoenmakers, K. van Summeren, A. V. van Vliet +4 more
2021Communications Biology15 citations Open access
Semantic Scholar
Spike gene variability in porcine epidemic diarrhea virus as a determinant for virulence
Wen-Tao Li, B. Hangalapura, Paul van den Elzen, Erwin van den Born +3 more
2025Journal of Virology14 citations Open access
Semantic Scholar
Serological Survey of Retrovirus and Coronavirus Infections, including SARS-CoV-2, in Rural Stray Cats in The Netherlands, 2020–2022
Mirjam B. H. M. Duijvestijn, N. Schuurman, J. Vernooij, Michelle A. J. M. van Leeuwen +6 more
2023Viruses13 citations Open access
Semantic Scholar
Modulation of nucleotide metabolism by picornaviruses
Lonneke V. Nouwen, M. Breeuwsma, E. Zaal, C. V. D. van de Lest +6 more
2024PLoS Pathogens12 citations Open access
Semantic Scholar
Highly pathogenic avian influenza (HPAI) H5 virus exposure in domestic cats and rural stray cats, the Netherlands, October 2020 to June 2023
Mirjam B. H. M. Duijvestijn, N. Schuurman, J. Vernooij, Michelle A. J. M. van Leeuwen +6 more
2024Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin11 citations Open access
Semantic Scholar
Kinetic analysis of paramyxovirus-sialoglycan receptor interactions reveals virion motility
Xue-Sheng Wu, Maite Goebbels, Le-Meng Chao, T. Wennekes +3 more
2023PLoS Pathogens11 citations Open access
Semantic Scholar
Enterovirus D-68 Infection of Primary Rat Cortical Neurons: Entry, Replication, and Functional Consequences
K. C. Poelaert, R. V. van Kleef, Meng-Ying Liu, A. V. van Vliet +8 more
2023mBio11 citations Open access
Semantic Scholar
Mathematical modeling of plus-strand RNA virus replication to identify broad-spectrum antiviral treatment strategies
Carolin Zitzmann, Christopher Dächert, B. Schmid, H. M. van der Schaar +6 more
2023PLoS Comput. Biol.10 citations Open access
Semantic Scholar
Inhibition of H1 and H5 Influenza A Virus Entry by Diverse Macrocyclic Peptides Targeting the Hemagglutinin Stem Region
M. N. Pascha, V. Thijssen, Julia E. Egido, Mirte W. Linthorst +7 more
2022ACS Chemical Biology10 citations Open access
Semantic Scholar
Move and countermove: the integrated stress response in picorna- and coronavirus-infected cells
Chiara Aloise, J. Schipper, R. D. de Groot, F. V. van Kuppeveld
2022Current Opinion in Immunology10 citations Open access
Semantic Scholar
Quantification of Receptor Association, Dissociation, and NA-Dependent Motility of Influenza A Particles by Biolayer Interferometry.
E. de Vries, Hong-Bo Guo, Wenjuan Du, Meng-Ying Liu +2 more
2022Methods in molecular biology10 citations Open access
Semantic Scholar
Picornavirus security proteins promote the release of extracellular vesicle enclosed viruses via the modulation of host kinases
Kyra Defourny, Xin-Yi Pei, F. V. van Kuppeveld, E. N. Nolte-'t Hoen
2024PLoS Pathogens9 citations Open access
Semantic Scholar
Safety and efficacy of live attenuated PEDV vaccines for neonatal protection
Wen-Tao Li, B. Hangalapura, Paul van den Elzen, Erwin van den Born +3 more
2025npj Vaccines8 citations Open access
Semantic Scholar
The multifaceted role of the viral 2A protease in enterovirus replication and antagonism of host antiviral responses
J. Schipper, Chiara Aloise, S. Sutter, M. Zwaagstra +12 more
2025PLoS Pathogens7 citations Open access
Semantic Scholar

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