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M. Cicek · SciRah

Researcher profile · Semantic Scholar

M. Cicek

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M. Cicek — researcher profile on SciRah

h-index: 24
Works: 49
Citations: 1,853

Most-cited papers

The mechanism of substrate (aglycone) specificity in beta -glucosidases is revealed by crystal structures of mutant maize beta -glucosidase-DIMBOA, -DIMBOAGlc, and -dhurrin complexes.
M. Czjzek, M. Cicek, V. Zamboni, D. Bevan +2 more
2000Proceedings of the National Academy of Sciences of the United States of America191 citations Open access
Semantic Scholar
The AKT/IκB kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-κB and β-catenin
A. Agarwal, Kingshuk Das, Natalia Lerner, S. Sathe +3 more
2005Oncogene170 citations Open access
Semantic Scholar
Podocalyxin increases the aggressive phenotype of breast and prostate cancer cells in vitro through its interaction with ezrin.
S. Sizemore, M. Cicek, N. Sizemore, K. Ng +1 more
2007Cancer Research140 citations
Semantic Scholar
Crystal structure of a monocotyledon (maize ZMGlu1) beta-glucosidase and a model of its complex with p-nitrophenyl beta-D-thioglucoside.
M. Czjzek, M. Cicek, V. Zamboni, W. P. Burmeister +3 more
2001Biochemical Journal116 citations Open access
Semantic Scholar
Breast Cancer Metastasis Suppressor 1 Inhibits Gene Expression by Targeting Nuclear Factor-κB Activity
M. Cicek, R. Fukuyama, D. Welch, Nywana Sizemore +1 more
2005107 citations Open access
Semantic Scholar
Breast cancer metastasis suppressor 1 (BRMS1) inhibits osteopontin transcription by abrogating NF-κB activation
Rajeev S. Samant, David W. Clark, R. Fillmore, M. Cicek +6 more
2007Molecular Cancer106 citations Open access
Semantic Scholar
Loss of Breast Cancer Metastasis Suppressor 1 Protein Expression Predicts Reduced Disease-Free Survival in Subsets of Breast Cancer Patients
D. Hicks, B. Yoder, Sarah M. Short, S. Tarr +14 more
2006Clinical Cancer Research95 citations Open access
Semantic Scholar
The AKT/I kappa B kinase pathway promotes angiogenic/metastatic gene expression in colorectal cancer by activating nuclear factor-kappa B and beta-catenin.
A. Agarwal, Kingshuk Das, Natalia Lerner, S. Sathe +3 more
2005Oncogene92 citations
Semantic Scholar
Structure and Expression of a Dhurrinase (β-Glucosidase) from Sorghum
M. Cicek, A. Esen
199881 citations Open access
Semantic Scholar
Breast cancer bone metastasis and current small therapeutics
M. Cicek, M. Oursler
2007Cancer Metastasis Review62 citations
Semantic Scholar
Expression of soluble and catalytically active plant (monocot) beta-glucosidases in E. coli.
M. Cicek, Asim Esen
1999Biotechnology and Bioengineering56 citations
Semantic Scholar
The Aglycone Specificity-determining Sites Are Different in 2,4-Dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA)-glucosidase (Maize β-Glucosidase) and Dhurrinase (Sorghum β-Glucosidase)*
M. Cicek, D. Blanchard, D. Bevan, A. Esen
2000Journal of Biological Chemistry54 citations Open access
Semantic Scholar
Development, Characterization, and Applications of a Novel Estrogen Receptor Beta Monoclonal Antibody
Xianglin Wu, M. Subramaniam, V. Negron, M. Cicek +6 more
2012Journal of Cellular Biochemistry53 citations Open access
Semantic Scholar
Identification of metastasis-associated proteins through protein analysis of metastatic MDA-MB-435 and metastasis-suppressed BRMS1 transfected-MDA-MB-435 cells
M. Cicek, Rajeev S. Samant, M. Kinter, D. Welch +1 more
2004Clinical and Experimental Metastasis51 citations
Semantic Scholar
BRMS1 negatively regulates NF-κB–dependent uPA expression following recruitment of HDAC1 to the NF-κB binding site of the uPA promoter
M. Cicek, R. Fukuyama, M. Çiçek, S. Sizemore +3 more
2009Clinical and Experimental Metastasis49 citations Open access
Semantic Scholar
Role of IKK and oscillatory NFκB kinetics in MMP‐9 gene expression and chemoresistance to 5‐fluorouracil in RKO colorectal cancer cells
R. Fukuyama, K. Ng, M. Cicek, C. Kelleher +3 more
2007Molecular Carcinogenesis49 citations
Semantic Scholar
Breast cancer metastasis suppressor 1 inhibits gene expression by targeting nuclear factor-kappaB activity.
M. Cicek, R. Fukuyama, D. Welch, N. Sizemore +1 more
2005Cancer Research49 citations
Semantic Scholar
Endoxifen’s Molecular Mechanisms of Action Are Concentration Dependent and Different than That of Other Anti-Estrogens
J. Hawse, M. Subramaniam, M. Cicek, Xianglin Wu +8 more
2013PLoS ONE46 citations Open access
Semantic Scholar
Escholarship@umms Cell and Developmental Biology Publications and Presentations Cell and Developmental Biology Tieg1/klf10 Modulates Runx2 Expression and Activity in Osteoblasts Repository Citation Tieg1/klf10 Modulates Runx2 Expression and Activity in Osteoblasts Tieg1/klf10 Modulates Runx2 Express
J. Hawse, M. Cicek, Sarah B. Grygo, Cicek +19 more
46 citations
Semantic Scholar
TGF-β Inducible Early Gene 1 Regulates Osteoclast Differentiation and Survival by Mediating the NFATc1, AKT, and MEK/ERK Signaling Pathways
M. Cicek, A. Vrabel, C. Sturchio, Larry Pederson +4 more
2011PLoS ONE44 citations Open access
Semantic Scholar
2-Methoxyestradiol suppresses osteolytic breast cancer tumor progression in vivo.
M. Cicek, U. Iwaniec, M. Goblirsch, A. Vrabel +4 more
2007Cancer Research42 citations
Semantic Scholar
Identification of β-Glucosidase Aggregating Factor (BGAF) and Mapping of BGAF Binding Regions on Maize β-Glucosidase*
D. Blanchard, M. Cicek, Jialun Chen, A. Esen
2001Journal of Biological Chemistry35 citations Open access
Semantic Scholar
TGFβ Inducible Early Gene-1 Directly Binds to, and Represses, the OPG Promoter in Osteoblasts
M. Subramaniam, J. Hawse, Elizabeth S. Bruinsma, Sarah B. Grygo +3 more
2010Biochemical and Biophysical Research Communications - BBRC28 citations Open access
Semantic Scholar
TIEG1 modulates β-catenin sub-cellular localization and enhances Wnt signaling in bone
M. Subramaniam, M. Cicek, Kevin S. Pitel, Elizabeth S. Bruinsma +6 more
2017Nucleic Acids Research25 citations Open access
Semantic Scholar
TGFβ Inducible Early Gene-1 Plays an Important Role in Mediating Estrogen Signaling in the Skeleton
John R. Hawse, Kevin S. Pitel, M. Cicek, Kenneth A. Philbrick +9 more
2014Journal of Bone and Mineral Research20 citations Open access
Semantic Scholar
Structure and expression of a dhurrinase (beta-glucosidase) from sorghum.
M. Cicek, A. Esen
1998Plant Physiology10 citations
Semantic Scholar
The Effects of a Novel Hormonal Breast Cancer Therapy, Endoxifen, on the Mouse Skeleton
A. Gingery, M. Subramaniam, Kevin S. Pitel, Jordan M. Reese +8 more
2014PLoS ONE8 citations Open access
Semantic Scholar
Identification of beta-glucosidase aggregating factor (BGAF) and mapping of BGAF binding regions on Maize beta -glucosidase.
D. Blanchard, M. Cicek, J. Chen, A. Esen
2001Journal of Biological Chemistry7 citations
Semantic Scholar
Breast Cancer Metastasis Suppressor 1 Inhibits Gene Expression by Targeting Nuclear Factor-KB Activity
M. Cicek, R. Fukuyama, D. Welch, N. Sizemore +1 more
20056 citations
Semantic Scholar
Novel Aminoketooxime Ligand and Its Cu(II) and Mn(II) Complexes: Synthesis, Characterization and Molecular Docking Studies
Güvenç Görgülü, M. Cicek, B. Dede
20185 citations Open access
Semantic Scholar
Novel enhanced lung-colonizing variant of murine MBT-2 bladder cancer cells.
M. Horinaga, R. Fukuyama, T. Nishiyama, Kelley M. Harsch +5 more
2005Urology4 citations
Semantic Scholar
Synthesis and Characterization of a Novel Aminoketooxime Ligand and Enzymatic Efficiencies of Its Metal Complexes
Güvenç Görgülü, M. Cicek, B. Dede
20183 citations Open access
Semantic Scholar
Structure and Expression of a Dhurrinase ( b -Glucosidase) from Sorghum 1
M. Cicek, A. Esen
19983 citations
Semantic Scholar
In Vitro Cell Culture Model of Calcification: Molecular Regulation of Myofibroblast Differentiation to an Osteoblast Phenotype
N. Rajamannan, M. Cicek, J. Hawse, T. Spelsberg +1 more
20141 citations
Semantic Scholar
Abstract 673: KLF10 is a Critical Mediator of Wnt Signaling in Aortic Valve Interstitial Cells
N. Rajamannan, M. Cicek, J. Hawse, T. Spelsberg +1 more
20140 citations
Semantic Scholar
Experimental Model of Aortic Valve Calcification to Induce Osteoblast Differentiation
N. Rajamannan, M. Cicek, J. Hawse, T. Spelsberg +1 more
20140 citations
Semantic Scholar
P4-02-03: Biological Functions of Estrogen Receptor-beta and Its Variants in Breast Cancer.
J. Hawse, Xianglin Wu, M. Cicek, M. Subramaniam +5 more
20110 citations
Semantic Scholar
P3-16-09: Endoxifen, a Newly Developed Breast Cancer Drug, Has Anabolic Actions on the Mouse Skeleton.
J. Hawse, M. Cicek, M. Subramaniam, Kevin S. Pitel +9 more
20110 citations
Semantic Scholar
Differential proteome analysis of metastasis breast cancer cell line MDA-MB-435 and metastasis suppressed BRMS-1 transfected-MDA-MB-435
M. Cicek, Rajeev S. Samant, D. Welch, G. Casey
20030 citations
Semantic Scholar
Crystal structure of a Monocot (Maize ZMGlu1) beta-glucosidase in complex with p-Nitrophenyl-beta-D-thioglucoside
M. Czjzek, M. Cicek, D. Bevan, B. Henrissat +1 more
20010 citations
Semantic Scholar
Crystal structure of a Monocot (Maize ZMGlu1) beta-glucosidase
M. Czjzek, M. Cicek, D. Bevan, B. Henrissat +1 more
20010 citations
Semantic Scholar
Crystal structure of the inactive mutant Monocot (Maize ZMGlu1) beta-glucosidase ZMGluE191D in complex with the natural aglycone DIMBOA
M. Czjzek, M. Cicek, D. Bevan, V. Zamboni +2 more
20000 citations
Semantic Scholar
Crystal structure of the inactive mutant Monocot (Maize ZMGlu1) beta-glucosidase ZMGluE191D in complex with the natural substrate DIMBOA-beta-D-glucoside
M. Czjzek, M. Cicek, D. Bevan, V. Zamboni +2 more
20000 citations
Semantic Scholar
Identification of BGAF and Mapping of BGAF Binding Domains on Maize (Zea mays L.) -glucosidase
D. Blanchard, M. Cicek, A. Esen
20000 citations
Semantic Scholar
Crystal structure of the inactive mutant Monocot (Maize ZMGlu1) beta-glucosidase ZM Glu191Asp
M. Czjzek, M. Cicek, D. Bevan, B. Henrissat +1 more
20000 citations
Semantic Scholar
Crystal structure of the inactive mutant Monocot (Maize ZMGlu1) beta-glucosidase ZMGluE191D in complex with the competitive inhibitor dhurrin
M. Czjzek, M. Cicek, D. Bevan, V. Zamboni +2 more
20000 citations
Semantic Scholar
Mechanism of Substrate Specificity and Catalysis in Retaining β-Glucosidases From Maize and Sorghum
M. Cicek
19990 citations
Semantic Scholar
Changing the specificity of DIMBOA-glucosidase ( maize ß-glucosidase ) to that of dhurrinase ( sorghum ß-glucosidase ) by domain swapping within the C-terminal region
M. Cicek, D. Blanchard, D. Bevan, A. Esen
19990 citations
Semantic Scholar
Cloning and sequencing of a [beta]-glucosidase of cDNA from Sorghum bicolor (L.) Moench and analysis of expression in seedlings
M. Cicek
19960 citations
Semantic Scholar

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