Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

S. Brimijoin · SciRah

Researcher profile · Semantic Scholar

S. Brimijoin

Share profile

S. Brimijoin — researcher profile on SciRah

h-index: 43
Works: 168
Citations: 5,618

Most-cited papers

Abundant Tissue Butyrylcholinesterase and Its Possible Function in the Acetylcholinesterase Knockout Mouse
Bin Li, Judith A. Stribley, Andreea Ticu, Wei-Hua Xie +5 more
2000Journal of Neurochemistry362 citations Open access
Semantic Scholar
The role of acetylcholinesterase in the pathogenesis of Alzheimer's disease.
Tina M. Rees, S. Brimijoin
2003Drugs of Today156 citations
Semantic Scholar
Re-engineering butyrylcholinesterase as a cocaine hydrolase.
Hong Sun, Y. Pang, O. Lockridge, S. Brimijoin
2002Molecular Pharmacology141 citations
Semantic Scholar
A Cocaine Hydrolase Engineered from Human Butyrylcholinesterase Selectively Blocks Cocaine Toxicity and Reinstatement of Drug Seeking in Rats
S. Brimijoin, Yang Gao, Justin J. Anker, Luke A. Gliddon +5 more
2008Neuropsychopharmacology136 citations Open access
Semantic Scholar
CHOLINESTERASES AND THE FINE LINE BETWEEN POISON AND REMEDY
C. Pope, S. Brimijoin
2018Biochemical Pharmacology121 citations Open access
Semantic Scholar
Plasma butyrylcholinesterase regulates ghrelin to control aggression
V. Chen, Yang Gao, Liyi Geng, R. J. Parks +2 more
2015Proceedings of the National Academy of Sciences of the United States of America112 citations Open access
Semantic Scholar
Rats gain excess weight after developmental exposure to the organophosphorothionate pesticide, chlorpyrifos.
T. L. Lassiter, S. Brimijoin
2008Neurotoxicology and Teratology100 citations
Semantic Scholar
Physiological Roles for Butyrylcholinesterase: A BChE-Ghrelin Axis
S. Brimijoin, V. Chen, Y. Pang, Liyi Geng +1 more
2016Chemico-Biological Interactions98 citations Open access
Semantic Scholar
Direct evidence for an adhesive function in the noncholinergic role of acetylcholinesterase in neurite outgrowth
Karun V. Sharma, C. Koenigsberger, S. Brimijoin, J. Bigbee
2001Journal of Neuroscience Research98 citations
Semantic Scholar
Rational design of alkylene-linked bis-pyridiniumaldoximes as improved acetylcholinesterase reactivators.
Y. Pang, T. Kollmeyer, F. Hong, Jong-Cheol Lee +3 more
2003Chemistry and Biology91 citations Open access
Semantic Scholar
Cocaine metabolism accelerated by a re-engineered human butyrylcholinesterase.
Hong Sun, Maryann L Shen, Y. Pang, O. Lockridge +1 more
2002Journal of Pharmacology and Experimental Therapeutics91 citations
Semantic Scholar
Amyloid‐beta increases acetylcholinesterase expression in neuroblastoma cells by reducing enzyme degradation
William Hu, Noah W. Gray, S. Brimijoin
2003Journal of Neurochemistry87 citations
Semantic Scholar
Predicted Michaelis-Menten Complexes of Cocaine-Butyrylcholinesterase
Hong Sun, J. El Yazal, O. Lockridge, L. Schopfer +2 more
2001Journal of Biological Chemistry81 citations Open access
Semantic Scholar
Novel and Viable Acetylcholinesterase Target Site for Developing Effective and Environmentally Safe Insecticides
Y. Pang, S. Brimijoin, D. Ragsdale, Kun Zhu +1 more
2012Current Drug Targets71 citations Open access
Semantic Scholar
Pure human butyrylcholinesterase hydrolyzes octanoyl ghrelin to desacyl ghrelin.
L. Schopfer, O. Lockridge, S. Brimijoin
2015General and Comparative Endocrinology61 citations
Semantic Scholar
Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice.
Tina M. Rees, Amit Berson, E. Sklan, L. Younkin +3 more
2005Current Alzheimer Research61 citations
Semantic Scholar
An albumin-butyrylcholinesterase for cocaine toxicity and addiction: catalytic and pharmacokinetic properties.
Yang Gao, David W. Lafleur, Rutul R. Shah, Qing-Hai Zhao +2 more
2008Chemico-Biological Interactions59 citations Open access
Semantic Scholar
Butyrylcholinesterase Deficiency Promotes Adipose Tissue Growth and Hepatic Lipid Accumulation in Male Mice on High-Fat Diet.
V. Chen, Yang Gao, Liyi Geng, Michael B. Stout +2 more
2016Endocrinology56 citations Open access
Semantic Scholar
Differential CSF butyrylcholinesterase levels in Alzheimer's disease patients with the ApoE epsilon4 allele, in relation to cognitive function and cerebral glucose metabolism.
T. Darreh-Shori, S. Brimijoin, A. Kadir, O. Almkvist +1 more
2006Neurobiology of Disease52 citations Open access
Semantic Scholar
Selective and Irreversible Inhibitors of Aphid Acetylcholinesterases: Steps Toward Human-Safe Insecticides
Y. Pang, Sanjay K. Singh, Yang Gao, T. L. Lassiter +3 more
2009PLoS ONE48 citations Open access
Semantic Scholar
The future potential for cocaine vaccines
F. Orson, Rongfu Wang, S. Brimijoin, B. Kinsey +4 more
2014Expert Opinion on Biological Therapy47 citations Open access
Semantic Scholar
Selective and Irreversible Inhibitors of Mosquito Acetylcholinesterases for Controlling Malaria and Other Mosquito-Borne Diseases
Y. Pang, F. Ekström, Gregory A. Polsinelli, Yang Gao +11 more
2009PLoS ONE47 citations Open access
Semantic Scholar
Gene Transfer of Cocaine Hydrolase Suppresses Cardiovascular Responses to Cocaine in Rats
Yang Gao, E. Atanasova, N. Sui, J. Pancook +2 more
2005Molecular Pharmacology47 citations
Semantic Scholar
Expression and transport of Angiotensin II AT1 receptors in spinal cord, dorsal root ganglia and sciatic nerve of the rat
J. Pavel, Hui Tang, S. Brimijoin, A. Moughamian +3 more
2008Brain Research46 citations Open access
Semantic Scholar
17α‐estradiol acts through hypothalamic pro‐opiomelanocortin expressing neurons to reduce feeding behavior
F. Steyn, S. Ngo, V. Chen, Lora C. Bailey-Downs +7 more
2017Aging Cell44 citations Open access
Semantic Scholar
Krüppel-like Factor 11 Differentially Couples to Histone Acetyltransferase and Histone Methyltransferase Chromatin Remodeling Pathways to Transcriptionally Regulate Dopamine D2 Receptor in Neuronal Cells
S. Seo, G. Lomberk, Angela J. Mathison, N. Buttar +6 more
2012Journal of Biological Chemistry44 citations Open access
Semantic Scholar
Gene Transfer of Mutant Mouse Cholinesterase Provides High Lifetime Expression and Reduced Cocaine Responses with No Evident Toxicity
Liyi Geng, Yang Gao, Xia-Bin Chen, Shurong Hou +6 more
2013PLoS ONE41 citations Open access
Semantic Scholar
Cocaine hydrolase encoded in viral vector blocks the reinstatement of cocaine seeking in rats for 6 months
Justin J. Anker, S. Brimijoin, Yang Gao, Liyi Geng +3 more
2011Biological Psychiatry39 citations Open access
Semantic Scholar
Roles of dopaminergic innervation of nucleus accumbens shell and dorsolateral caudate-putamen in cue-induced morphine seeking after prolonged abstinence and the underlying D1- and D2-like receptor mechanisms in rats
Jun Gao, Yonghui Li, Ning Zhu, S. Brimijoin +1 more
2012Journal of Psychopharmacology37 citations Open access
Semantic Scholar
An Engineered Cocaine Hydrolase Blunts and Reverses Cardiovascular Responses to Cocaine in Rats
Yang Gao, S. Brimijoin
2004Journal of Pharmacology and Experimental Therapeutics37 citations
Semantic Scholar
Combined Cocaine Hydrolase Gene Transfer and Anti-Cocaine Vaccine Synergistically Block Cocaine-Induced Locomotion
M. Carroll, Natalie E. Zlebnik, Justin J. Anker, T. Kosten +6 more
2012PLoS ONE35 citations Open access
Semantic Scholar
The Concept of Pharmacologic Cocaine Interception as a Treatment for Drug Abuse
Yang Gao, F. Orson, B. Kinsey, T. Kosten +1 more
2010Chemico-Biological Interactions35 citations Open access
Semantic Scholar
Plant-expressed cocaine hydrolase variants of butyrylcholinesterase exhibit altered allosteric effects of cholinesterase activity and increased inhibitor sensitivity
Katherine E. Larrimore, I. Kazan, Latha Kannan, R. Player Kendle +7 more
2017Scientific Reports34 citations Open access
Semantic Scholar
Prospects, Promise and Problems on the Road to Effective Vaccines and Related Therapies for Substance Abuse
S. Brimijoin, Xiaoyun Y. Shen, F. Orson, T. Kosten
2013Expert Review of Vaccines32 citations Open access
Semantic Scholar
Novel Messenger RNA and Alternative Promoter for Murine Acetylcholinesterase*
E. Atanasova, S. Chiappa, E. Wieben, S. Brimijoin
1999Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Anti-cocaine antibody and butyrylcholinesterase-derived cocaine hydrolase exert cooperative effects on cocaine pharmacokinetics and cocaine-induced locomotor activity in mice
S. Brimijoin, F. Orson, T. Kosten, B. Kinsey +3 more
2012Chemico-Biological Interactions30 citations Open access
Semantic Scholar
Effects of cocaine hydrolase on cocaine self-administration under a PR schedule and during extended access (escalation) in rats
M. Carroll, Yang Gao, S. Brimijoin, Justin J. Anker
2010Psychopharmacology30 citations Open access
Semantic Scholar
Butyrylcholinesterase gene transfer in obese mice prevents postdieting body weight rebound by suppressing ghrelin signaling
V. Chen, Yang Gao, Liyi Geng, S. Brimijoin
2017Proceedings of the National Academy of Sciences of the United States of America29 citations Open access
Semantic Scholar
Lasting Reduction of Cocaine Action in Neostriatum— A Hydrolase Gene Therapy Approach
Yang Gao, S. Brimijoin
2009Journal of Pharmacology and Experimental Therapeutics28 citations Open access
Semantic Scholar
Cerebrospinal fluid acetylcholinesterase changes after treatment with donepezil in patients with Alzheimer’s disease
M. García-Ayllón, M. Silveyra, N. Andreasen, S. Brimijoin +2 more
2007Journal of Neurochemistry28 citations
Semantic Scholar
Long-Term Reduction of Cocaine Self-Administration in Rats Treated with Adenoviral Vector-Delivered Cocaine Hydrolase: Evidence for Enzymatic Activity
Natalie E. Zlebnik, S. Brimijoin, Yang Gao, A. Saykao +2 more
2014Neuropsychopharmacology27 citations Open access
Semantic Scholar
Effects of anti-cocaine vaccine and viral gene transfer of cocaine hydrolase in mice on cocaine toxicity including motor strength and liver damage
Yang Gao, Liyi Geng, F. Orson, B. Kinsey +3 more
2012Chemico-Biological Interactions27 citations Open access
Semantic Scholar
Physiologic and metabolic safety of butyrylcholinesterase gene therapy in mice
V. Murthy, Yang Gao, Liyi Geng, N. LeBrasseur +3 more
2014Vaccine25 citations Open access
Semantic Scholar
Preclinical Studies on Neurobehavioral and Neuromuscular Effects of Cocaine Hydrolase Gene Therapy in Mice
V. Murthy, Yang Gao, Liyi Geng, N. LeBrasseur +2 more
2013Journal of Molecular Neuroscience24 citations Open access
Semantic Scholar
Radiometric solvent-partitioning assay for screening cocaine hydrolases and measuring cocaine levels in milligram tissue samples.
S. Brimijoin, Maryann L Shen, Hong Sun
2002Analytical Biochemistry24 citations
Semantic Scholar
Suppression of neurite outgrowth by high-dose nerve growth factor is independent of functional p75NTR receptors.
A. M. Conti, S. Brimijoin, L. Miller, A. Windebank
2004Neurobiology of Disease23 citations Open access
Semantic Scholar
In vivo localization of human acetylcholinesterase-derived species in a β-sheet conformation at the core of senile plaques in Alzheimer's disease
Létitia Jean, S. Brimijoin, D. Vaux
2019Journal of Biological Chemistry22 citations Open access
Semantic Scholar
Treating Cocaine Addiction, Obesity, and Emotional Disorders by Viral Gene Transfer of Butyrylcholinesterase
S. Brimijoin, Yang Gao, Liyi Geng, V. Chen
2018Frontiers in Pharmacology21 citations Open access
Semantic Scholar
Comparison of 5 monoclonal antibodies for immunopurification of human butyrylcholinesterase on Dynabeads: KD values, binding pairs, and amino acid sequences
Hong Peng, S. Brimijoin, A. Hrabovská, Katarina Targosova +5 more
2015Chemico-Biological Interactions21 citations Open access
Semantic Scholar
Regional and cellular distribution of DREAM in adult rat brain consistent with multiple sensory processing roles.
P. Hammond, T. Craig, R. Kumar, S. Brimijoin
2003Brain Research. Molecular Brain Research20 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

Yang Gao×22
Invite
Yang Gao — researcher profile on SciRah
Liyi Geng×10
Invite
Liyi Geng — researcher profile on SciRah
Y. Pang×9
Invite
Y. Pang — researcher profile on SciRah
O. Lockridge×6
Invite
O. Lockridge — researcher profile on SciRah

×6

Invite

V. Chen — researcher profile on SciRah

Invite

R. J. Parks — researcher profile on SciRah

Invite

F. Orson — researcher profile on SciRah

Invite

T. Kosten — researcher profile on SciRah

Invite

M. Carroll — researcher profile on SciRah

Invite

B. Kinsey — researcher profile on SciRah

Invite

Hong Sun — researcher profile on SciRah

Justin J. Anker×4

Invite

Justin J. Anker — researcher profile on SciRah