M. Ikebe

Most-cited papers

Myosin Vb Mobilizes Recycling Endosomes and AMPA Receptors for Postsynaptic Plasticity
Zhi-Ping Wang, J. G. Edwards, Nathan J. Riley, D. Provance +7 more
2008Cell492 citations Open access
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Head-head and head-tail interaction: a general mechanism for switching off myosin II activity in cells.
H. Jung, S. Komatsu, M. Ikebe, R. Craig
2008Molecular Biology of the Cell191 citations Open access
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Exosomes in Human Breast Milk Promote EMT
Wenyi Qin, Y. Tsukasaki, S. Dasgupta, N. Mukhopadhyay +2 more
2016Clinical Cancer Research132 citations Open access
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The Cellular and Molecular Basis of Bitter Tastant-Induced Bronchodilation
Cheng-Hai Zhang, Lawrence M. Lifshitz, K. Uy, M. Ikebe +2 more
2013PLoS Biology127 citations Open access
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Single Molecule Stepping and Structural Dynamics of Myosin X
Yu-Jie Sun, O. Sato, F. Ruhnow, Mark E. Arsenault +2 more
2010Nature Structural &Molecular Biology101 citations Open access
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Phospholipid-dependent regulation of the motor activity of myosin X
N. Umeki, H. Jung, T. Sakai, O. Sato +2 more
2011Nature Structural &Molecular Biology99 citations
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Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals
K. Lee, Guidenn Sulbarán, Shixin Yang, Young-Mun Ji +10 more
2018Proceedings of the National Academy of Sciences of the United States of America98 citations Open access
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The tail binds to the head–neck domain, inhibiting ATPase activity of myosin VIIA
N. Umeki, H. Jung, Shinya Watanabe, T. Sakai +4 more
2009Proceedings of the National Academy of Sciences of the United States of America87 citations Open access
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Myosin-X Induces Filopodia by Multiple Elongation Mechanism*
Tomonobu M. Watanabe, Hiroshi Tokuo, K. Gonda, H. Higuchi +1 more
2010Journal of Biological Chemistry84 citations Open access
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Force-dependent detachment of kinesin-2 biases track switching at cytoskeletal filament intersections.
Harry W. Schroeder, Adam G. Hendricks, Kazuho Ikeda, H. Shuman +4 more
2012Biophysical Journal79 citations Open access
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The globular tail domain puts on the brake to stop the ATPase cycle of myosin Va
Xiang-Dong Li, H. Jung, Qizhi Wang, R. Ikebe +2 more
2008Proceedings of the National Academy of Sciences of the United States of America79 citations Open access
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Cargo binding activates myosin VIIA motor function in cells
T. Sakai, N. Umeki, R. Ikebe, M. Ikebe
2011Proceedings of the National Academy of Sciences of the United States of America73 citations Open access
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Regulation of the function of mammalian myosin and its conformational change.
M. Ikebe
2008Biochemical and Biophysical Research Communications - BBRC67 citations
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Human airway contraction and formoterol-induced relaxation is determined by Ca2+ oscillations and Ca2+ sensitivity.
A. Ressmeyer, Yan Bai, P. Delmotte, K. Uy +5 more
2010American Journal of Respiratory Cell and Molecular Biology62 citations Open access
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PD-L1 mediates lung fibroblast to myofibroblast transition through Smad3 and β-catenin signaling pathways
Xia Guo, C. Sunil, O. Adeyanju, A. Parker +5 more
2022Scientific Reports57 citations Open access
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Complex-I Alteration and Enhanced Mitochondrial Fusion Are Associated With Prostate Cancer Progression
J. Philley, Anbarasu Kannan, W. Qin, E. Sauter +5 more
2015Journal of Cellular Physiology53 citations Open access
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Fibrin turnover and pleural organization: bench to bedside.
A. Komissarov, N. Rahman, Y. C. Gary Lee, G. Florova +6 more
2018American Journal of Physiology - Lung cellular and Molecular Physiology51 citations Open access
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Mitochondrial Reprogramming Regulates Breast Cancer Progression
Anbarasu Kannan, Robert B. Wells, S. Sivakumar, S. Komatsu +8 more
2016Clinical Cancer Research50 citations Open access
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Plasminogen Activator Inhibitor-1 Suppresses Profibrotic Responses in Fibroblasts from Fibrotic Lungs*
A. Marudamuthu, S. Shetty, Y. Bhandary, Sophia Karandashova +11 more
2015Journal of Biological Chemistry50 citations Open access
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Total Internal Reflection Fluorescence (TIRF) Microscopy of Chlamydomonas Flagella
B. Engel, Karl F. Lechtreck, T. Sakai, M. Ikebe +2 more
2009Methods in Cell Biology46 citations Open access
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Myosin X is recruited to nascent focal adhesions at the leading edge and induces multi-cycle filopodial elongation
Kangmin He, T. Sakai, Y. Tsukasaki, Tomonobu M. Watanabe +1 more
2017Scientific Reports43 citations Open access
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Uterine artery myosin phosphatase isoform switching and increased sensitivity to SNP in a rat L-NAME model of hypertension of pregnancy.
Yuan Lu, Haiying Zhang, N. Gokina, M. Mandalá +4 more
2008American Journal of Physiology - Cell Physiology42 citations
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NK-CD11c+ Cell Crosstalk in Diabetes Enhances IL-6-Mediated Inflammation during Mycobacterium tuberculosis Infection
S. Cheekatla, D. Tripathi, Sambasivan Venkatasubramanian, Pavan Kumar Nathella +9 more
2016PLoS Pathogens40 citations Open access
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p53- and PAI-1-mediated induction of C-X-C chemokines and CXCR2: importance in pulmonary inflammation due to cigarette smoke exposure.
Nivedita Tiwari, A. Marudamuthu, Y. Tsukasaki, M. Ikebe +2 more
2016American Journal of Physiology - Lung cellular and Molecular Physiology40 citations Open access
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Structure and Regulation of the Movement of Human Myosin VIIA*
T. Sakai, H. Jung, O. Sato, M. Yamada +3 more
2015Journal of Biological Chemistry37 citations Open access
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Rac1 Regulates Myosin II Phosphorylation Through Regulation of Myosin Light Chain Phosphatase
Keita Shibata, Hiroyasu Sakai, Qian Huang, Hirotoshi Kamata +4 more
2015Journal of Cellular Physiology37 citations
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Inhibition of Glycogen Synthase Kinase 3β Blocks Mesomesenchymal Transition and Attenuates Streptococcus pneumonia-Mediated Pleural Injury in Mice.
J. Boren, Grant Shryock, Alexis Fergis, A. Jeffers +8 more
2017American Journal of Pathology34 citations Open access
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Mesomesenchymal transition of pleural mesothelial cells is PI3K and NF-κB dependent.
S. Owens, A. Jeffers, J. Boren, Y. Tsukasaki +4 more
2015American Journal of Physiology - Lung cellular and Molecular Physiology34 citations Open access
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Correction: The Cellular and Molecular Basis of Bitter Tastant-Induced Bronchodilation
Cheng-Hai Zhang, Lawrence M. Lifshitz, K. Uy, M. Ikebe +2 more
2013PLoS Biology31 citations Open access
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Mitochondria-associated myosin 19 processively transports mitochondria on actin tracks in living cells
O. Sato, T. Sakai, Young-yeon Choo, R. Ikebe +2 more
2022Journal of Biological Chemistry26 citations Open access
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Human myosin VIIa is a very slow processive motor protein on various cellular actin structures
O. Sato, S. Komatsu, T. Sakai, Y. Tsukasaki +5 more
2017Journal of Biological Chemistry25 citations Open access
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The effect of novel mutations on the structure and enzymatic activity of unconventional myosins associated with autosomal dominant non-syndromic hearing loss
Tae-Jun Kwon, Se-Kyung Oh, Hong-Joon Park, O. Sato +10 more
2014Open Biology24 citations Open access
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Organizing empyema induced in mice by Streptococcus pneumoniae: effects of plasminogen activator inhibitor-1 deficiency
T. Tucker, A. Jeffers, J. Boren, B. Quaid +7 more
2016Clinical and Translational Medicine20 citations Open access
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The central role of the tail in switching off 10S myosin II activity
Shixin Yang, K. Lee, J. Woodhead, O. Sato +2 more
2019The Journal of General Physiology19 citations Open access
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KIF5A transports collagen vesicles of myofibroblasts during pleural fibrosis
Hirotoshi Kamata, Y. Tsukasaki, T. Sakai, R. Ikebe +9 more
2017Scientific Reports19 citations Open access
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DOCK2 Promotes Pleural Fibrosis by Modulating Mesothelial to Mesenchymal Transition.
G. Qian, O. Adeyanju, Saptarshi Roy, C. Sunil +5 more
2021American Journal of Respiratory Cell and Molecular Biology18 citations Open access
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Myocardin is Involved in Mesothelial-Mesenchymal Transition of Human Pleural Mesothelial Cells.
T. Tucker, Y. Tsukasaki, T. Sakai, Shinya Mitsuhashi +4 more
2019American Journal of Respiratory Cell and Molecular Biology17 citations Open access
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ZIPK is critical for the motility and contractility of VSMCs through the regulation of nonmuscle myosin II isoforms.
S. Komatsu, M. Ikebe
2014American Journal of Physiology. Heart and Circulatory Physiology17 citations Open access
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Impacts of Usher Syndrome Type IB Mutations on Human Myosin VIIa Motor Function
Shinya Watanabe, N. Umeki, R. Ikebe, M. Ikebe
2008Biochemistry17 citations Open access
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Proliferative regulation of alveolar epithelial type 2 progenitor cells by human Scnn1d gene
Runzhen Zhao, Gibran Ali, Jianjun Chang, S. Komatsu +13 more
2019Theranostics15 citations Open access
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Smooth muscle function and myosin polymerization
P. Chitano, Lu Wang, Gabrielle Y Y Tin, M. Ikebe +2 more
2017Journal of Cell Science15 citations
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Activated full-length myosin-X moves processively on filopodia with large steps toward diverse two-dimensional directions
O. Sato, H. Jung, S. Komatsu, Y. Tsukasaki +3 more
2017Scientific Reports14 citations Open access
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Phosphorylation of myosin II regulatory light chain by ZIP kinase is responsible for cleavage furrow ingression during cell division in mammalian cultured cells
Kosuke Hosoba, S. Komatsu, M. Ikebe, Manato Kotani +4 more
2015Biochemical and Biophysical Research Communications - BBRC13 citations Open access
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The Antiparallel Dimerization of Myosin X Imparts Bundle Selectivity for Processive Motility.
M. Caporizzo, C. Fishman, O. Sato, Ryan M. Jamiolkowski +2 more
2018Biophysical Journal12 citations Open access
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The mTORC2/SGK1/NDRG1 Signaling Axis Is Critical for Mesomesenchymal Transition of Pleural Mesothelial Cells and the Progression of Pleural Fibrosis.
S. Keshava, S. Owens, W. Qin, A. Jeffers +6 more
2023American Journal of Respiratory Cell and Molecular Biology11 citations Open access
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Effect of Phosphorylation in the Motor Domain of Human Myosin IIIA on Its ATP Hydrolysis Cycle
Shigeru Komaba, Shinya Watanabe, N. Umeki, O. Sato +1 more
2010Biochemistry11 citations Open access
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Adenoprotection of the heart involves phospholipase C-induced activation and translocation of PKC-epsilon to RACK2 in adult rat and mouse.
R. Fenton, S. Komatsu, M. Ikebe, Lynne G. Shea +1 more
2009American Journal of Physiology. Heart and Circulatory Physiology11 citations Open access
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Calponin 1 contributes to myofibroblast differentiation of human pleural mesothelial cells.
Young-yeon Choo, T. Sakai, S. Komatsu, R. Ikebe +5 more
2022American Journal of Physiology - Lung cellular and Molecular Physiology10 citations Open access
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Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes
S. Komatsu, J. Dobson, M. Ikebe, Lynne G. Shea +1 more
2012Journal of Cellular Physiology10 citations Open access
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Mechanical Characterization of One-Headed Myosin-V Using Optical Tweezers
Tomonobu M. Watanabe, A. Iwane, Hiroto Tanaka, M. Ikebe +1 more
2010PLoS ONE10 citations Open access
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