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K. Peskov · SciRah

Researcher profile · Semantic Scholar

K. Peskov

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K. Peskov — researcher profile on SciRah

h-index: 18
Works: 54
Citations: 911

Most-cited papers

Radiation and PD-(L)1 treatment combinations: immune response and dose optimization via a predictive systems model
Yuri Kosinsky, S. Dovedi, K. Peskov, Veronika M. Voronova +5 more
2018Journal of Immunotherapy for Cancer96 citations Open access
Semantic Scholar
Quantitative Systems Pharmacology: An Exemplar Model‐Building Workflow With Applications in Cardiovascular, Metabolic, and Oncology Drug Development
G. Helmlinger, V. Sokolov, K. Peskov, K. Hallow +10 more
2019CPT: Pharmacometrics & Systems Pharmacology69 citations Open access
Semantic Scholar
Agent Based Modeling of Human Gut Microbiome Interactions and Perturbations
T. Shashkova, A. Popenko, A. Tyakht, K. Peskov +6 more
2016PLoS ONE68 citations Open access
Semantic Scholar
Kinetic modelling of central carbon metabolism in Escherichia coli
K. Peskov, E. Mogilevskaya, O. Demin
2012The FEBS Journal58 citations
Semantic Scholar
DBSolve Optimum: a software package for kinetic modeling which allows dynamic visualization of simulation results
N. Gizzatkulov, I. Goryanin, E. Metelkin, E. Mogilevskaya +2 more
2010BMC Systems Biology50 citations Open access
Semantic Scholar
Applications of Model-Based Meta-Analysis in Drug Development
P. Chan, K. Peskov, Xuyang Song
2022Pharmaceutical Research49 citations Open access
Semantic Scholar
A Physiology-Based Model of Bile Acid Distribution and Metabolism Under Healthy and Pathologic Conditions in Human Beings
Veronika M. Voronova, V. Sokolov, A. Al‐Khaifi, S. Straniero +5 more
2020Cellular and Molecular Gastroenterology and Hepatology44 citations Open access
Semantic Scholar
Drug-disease modeling in the pharmaceutical industry - where mechanistic systems pharmacology and statistical pharmacometrics meet.
G. Helmlinger, N. Al-Huniti, S. Aksenov, K. Peskov +9 more
2017European Journal of Pharmaceutical Sciences42 citations
Semantic Scholar
Dose dependence of treatment-related adverse events for immune checkpoint inhibitor therapies: a model-based meta-analysis
B. Shulgin, Yuri Kosinsky, A. Omelchenko, Lu-Lu Chu +7 more
2020Oncoimmunology39 citations Open access
Semantic Scholar
Combination of immune checkpoint inhibitors with radiation therapy in cancer: A hammer breaking the wall of resistance
Veronika M. Voronova, Anastasia Vislobokova, K. Mutig, Mikhail Samsonov +5 more
2022Frontiers in Oncology37 citations Open access
Semantic Scholar
Differentiating the Sodium‐Glucose Cotransporter 1 Inhibition Capacity of Canagliflozin vs. Dapagliflozin and Empagliflozin Using Quantitative Systems Pharmacology Modeling
V. Sokolov, T. Yakovleva, Lu-Lu Chu, Wei-Feng Tang +6 more
2020CPT: Pharmacometrics & Systems Pharmacology37 citations Open access
Semantic Scholar
Quantitative Mechanistic Modeling in Support of Pharmacological Therapeutics Development in Immuno-Oncology
K. Peskov, Ivan Azarov, Lu-Lu Chu, Veronika M. Voronova +2 more
2019Frontiers in Immunology36 citations Open access
Semantic Scholar
Comparison of the urinary glucose excretion contributions of SGLT2 and SGLT1: A quantitative systems pharmacology analysis in healthy individuals and patients with type 2 diabetes treated with SGLT2 inhibitors
T. Yakovleva, V. Sokolov, Lu-Lu Chu, Wei-Feng Tang +7 more
2019Diabetes, obesity and metabolism29 citations
Semantic Scholar
Longitudinal Tumor Size and Neutrophil‐to‐Lymphocyte Ratio Are Prognostic Biomarkers for Overall Survival in Patients With Advanced Non‐Small Cell Lung Cancer Treated With Durvalumab
Sergey Gavrilov, K. Zhudenkov, G. Helmlinger, J. Dunyak +2 more
2020CPT: Pharmacometrics & Systems Pharmacology28 citations Open access
Semantic Scholar
Role of T Cell-To-Dendritic Cell Chemoattraction in T Cell Priming Initiation in the Lymph Node: An Agent-Based Modeling Study
Ivan Azarov, K. Peskov, G. Helmlinger, Yuri Kosinsky
2019Frontiers in Immunology26 citations Open access
Semantic Scholar
Comparative quantitative systems pharmacology modeling of anti-PCSK9 therapeutic modalities in hypercholesterolemia
V. Sokolov, G. Helmlinger, C. Nilsson, K. Zhudenkov +5 more
2019Journal of Lipid Research22 citations Open access
Semantic Scholar
Kinetic Model of phosphofructokinase-1 from Escherichia coli
K. Peskov, I. Goryanin, O. Demin
2008J. Bioinform. Comput. Biol.20 citations
Semantic Scholar
Evaluation of Combination Strategies for the A2AR Inhibitor AZD4635 Across Tumor Microenvironment Conditions via a Systems Pharmacology Model
Veronika M. Voronova, K. Peskov, Yuri Kosinsky, G. Helmlinger +10 more
2021Frontiers in Immunology18 citations Open access
Semantic Scholar
A workflow for the joint modeling of longitudinal and event data in the development of therapeutics: Tools, statistical methods, and diagnostics
K. Zhudenkov, Sergey Gavrilov, A. Sofronova, O. Stepanov +3 more
2022CPT: Pharmacometrics & Systems Pharmacology16 citations Open access
Semantic Scholar
Kinetic modeling as a tool to integrate multilevel dynamic experimental data.
E. Mogilevskaya, N. Bagrova, T. Plyusnina, N. Gizzatkulov +9 more
2009Methods in molecular biology14 citations
Semantic Scholar
Elaborating on anti CTLA-4 mechanisms of action using an agent-based modeling approach
Ivan Azarov, G. Helmlinger, Yuri Kosinsky, K. Peskov
2022Frontiers in Applied Mathematics and Statistics13 citations Open access
Semantic Scholar
Interpretation of metabolic memory phenomenon using a physiological systems model: What drives oxidative stress following glucose normalization?
Veronika M. Voronova, K. Zhudenkov, G. Helmlinger, K. Peskov
2017PLoS ONE13 citations Open access
Semantic Scholar
Evaluation of therapeutic strategies targeting BCAA catabolism using a systems pharmacology model
Veronika M. Voronova, V. Sokolov, Yannick Morias, Malin Jonsson Boezelman +6 more
2022Frontiers in Pharmacology12 citations Open access
Semantic Scholar
Longitudinal FEV1 and Exacerbation Risk in COPD: Quantifying the Association Using Joint Modelling
K. Zhudenkov, R. Palmer, A. Jauhiainen, G. Helmlinger +4 more
2021International Journal of COPD10 citations Open access
Semantic Scholar
Quantification of Scheduling Impact on Safety and Efficacy Outcomes of Brain Metastasis Radio- and Immuno-Therapies: A Systematic Review and Meta-Analysis
Veronika M. Voronova, S. Lebedeva, M. Sekacheva, G. Helmlinger +1 more
2020Frontiers in Oncology10 citations Open access
Semantic Scholar
Exenatide effects on gastric emptying rate and the glucose rate of appearance in plasma: A quantitative assessment using an integrative systems pharmacology model
Veronika M. Voronova, K. Zhudenkov, R. Penland, D. Boulton +2 more
2018Diabetes, obesity and metabolism10 citations
Semantic Scholar
Semi-Mechanistic Pharmacokinetic-Pharmacodynamic Model of Camostat Mesylate-Predicted Efficacy against SARS-CoV-2 in COVID-19
Yuri Kosinsky, K. Peskov, D. Stanski, D. Wetmore +1 more
2022Microbiology spectrum8 citations Open access
Semantic Scholar
Decision letter for "Urinary glucose excretion contributions of SGLT2 vs . SGLT1 transporters: a quantitative systems pharmacology analysis in healthy and T2DM subjects administered SGLT2 inhibitors"
T. Yakovleva, V. Sokolov, Lu-Lu Chu, Wei-Feng Tang +7 more
20196 citations Open access
Semantic Scholar
An integrative mechanistic model of thymocyte dynamics
Victoria Kulesh, K. Peskov, G. Helmlinger, Gennady Bocharov
2024Frontiers in Immunology5 citations Open access
Semantic Scholar
Mathematical modeling of endogenous and exogenously administered T cell recirculation in mouse and its application to pharmacokinetic studies of cell therapies
A. Nikitich, G. Helmlinger, K. Peskov, Gennady Bocharov
2024Frontiers in Immunology5 citations Open access
Semantic Scholar
Kinetic Modeling of ACE operon Genetic Regulation in Escherichia coli
K. Peskov, I. Goryanin, K. Prank, F. Tobin +1 more
2008J. Bioinform. Comput. Biol.5 citations
Semantic Scholar
Cycle Network Model of Prostaglandin H Synthase-1
A. Goltsov, M. Swat, K. Peskov, Yuri Kosinsky
2020bioRxiv3 citations Open access
Semantic Scholar
Longitudinal tumor size and NLR as predictive factors of individual survival compared to their baseline values in patients with non-small cell lung cancer treated with durvalumab.
K. Zhudenkov, Sergey Gavrilov, K. Peskov, G. Helmlinger +1 more
2019Journal of Clinical Oncology2 citations
Semantic Scholar
Abstract 1082: Linking tumor microenvironment properties in murine syngeneic tumors with resistance to immune checkpoint inhibitors: Insights from a quantitative systems approach
G. Helmlinger, Ivan Azarov, Yuri Kosinsky, Veronika M. Voronova +4 more
2019Tumor Biology2 citations Open access
Semantic Scholar
Abstract 2098: Quantitative modeling as a systematic approach for drug combination evaluation in immuno-oncology (IO)
G. Helmlinger, Yuri Kosinsky, Lu-Lu Chu, K. Peskov +5 more
2018Tumor Biology2 citations
Semantic Scholar
Mathematical modeling: a new trend in the pharmaceutical industry
K. Peskov
20132 citations
Semantic Scholar
Kinetic modeling of E. coli enzymes: integration of in vitro data
E. Mogilevskaya, K. Peskov, E. Metelkin
20092 citations
Semantic Scholar
Abstract 2794: A Quantitative Systems Pharmacology (QSP) model to characterize dose-dependent antitumor activity of AZD5305, PARP1 selective inhibitor, across multiple xenograft models
Ganesha Moorthy, Veronika M. Voronova, Cesar Pichardo, K. Peskov +4 more
2023Cancer Research1 citations
Semantic Scholar
Efficacy of radiotherapy vs. The combination of radio- and immunotherapy: a systematic review and meta-analysis
Veronika M. Voronova, S. Lebedeva, M. Sekacheva, G. Helmlinger +1 more
20201 citations Open access
Semantic Scholar
Quantification of dose dependence and frequency of checkpoint inhibitor immune-mediated adverse events: A Bayesian model-based meta-analysis.
B. Shulgin, Yuri Kosinsky, A. Smirnova, G. Helmlinger +1 more
20201 citations
Semantic Scholar
Evaluation and diagnostic potential of plasma biomarkers in bladder cancer
V. Voronova, K. Peskov, P. Glybochko, A. Svistunov +7 more
2019Annals of Oncology1 citations Open access
Semantic Scholar
Model-based meta-analysis of safety for immune checkpoint inhibitor combinations and monotherapy.
K. Abdallah, B. Shulgin, K. Peskov, Yuri Kosinsky +4 more
20171 citations
Semantic Scholar
Kinetic Modeling of E. coli Enzymes: Integration of in vitro Experimental Data
E. Mogilevskaya, K. Peskov, E. Metelkin, G. Lebedeva +3 more
20091 citations
Semantic Scholar
Population PK/PD Modeling and Simulation to Predict the Comparative Long-Term Efficacy of Olokizumab in Rheumatoid Arthritis Patients
Yuri Kosinsky, Ivan Azarov, K. Zhudenkov, K. Peskov +6 more
2026Journal of Clinical Medicine0 citations Open access
Semantic Scholar
Evaluation of Itacitinib Impact on TNFα Levels Following Immune Effector Cell (IEC) Therapy Using PKPD Modeling and Simulation Approaches
Olga Ivanova, M. Pratta, Ivan Azarov, K. Zhudenkov +4 more
2024Blood0 citations
Semantic Scholar
COPD_A_284720 101..111
R. Palmer, A. Jauhiainen, G. Helmlinger, O. Stepanov +3 more
20210 citations
Semantic Scholar
Abstract B55: Exploratory biomarker analyses of tumor and peripheral blood samples from the phase I durvalumab plus gefitinib trial in EGFR-mutated NSCLC
Tammie C. Yeh, H. Angell, V. Rowlands, E. V. Jones +10 more
20200 citations
Semantic Scholar
PD-0172: Radio/immuno-therapies of brain metastasis disease: A meta-analysis of efficacy and safety outcomes
V. Voronova, S. Lebedeva, M. Sekacheva, G. Helmlinger +1 more
20200 citations
Semantic Scholar
Comparative quantitative safety profiles of PD-1 and PD-L1 checkpoint inhibitor monotherapies: A Bayesian model-based meta-analysis.
B. Shulgin, A. Smirnova, Yuri Kosinsky, G. Helmlinger +1 more
20200 citations
Semantic Scholar
Quantitative Investigation of Pharmacologically Modulated Signaling and Efficacy in ABC DLBCL Using a Systems Pharmacology Model
Kosinsky Yuri, Lu-Lu Chu, Millie Shah, K. Vishwanathan +8 more
2019Blood0 citations Open access
Semantic Scholar

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