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C. Wirtz · SciRah

Researcher profile · Semantic Scholar

C. Wirtz

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C. Wirtz — researcher profile on SciRah

h-index: 40
Works: 182
Citations: 4,750

Most-cited papers

DeepSeg: deep neural network framework for automatic brain tumor segmentation using magnetic resonance FLAIR images
Ramy A. Zeineldin, M. E. Karar, J. Coburger, C. Wirtz +1 more
2020International Journal of Computer Assisted Radiology and Surgery228 citations Open access
Semantic Scholar
Explainability of deep neural networks for MRI analysis of brain tumors
Ramy A. Zeineldin, M. E. Karar, Ziad Elshaer, J. Coburger +3 more
2022International Journal of Computer Assisted Radiology and Surgery143 citations Open access
Semantic Scholar
Augmented reality-assisted ventriculostomy.
Max Schneider, Christian Kunz, Andrej Pal'a, C. Wirtz +2 more
2021Neurosurgical Focus64 citations Open access
Semantic Scholar
CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells
Moritz Drachsler, S. Kleber, Á. Mateos, K. Volk +10 more
2016Cell Death and Disease53 citations Open access
Semantic Scholar
Current state and future perspective of drug repurposing in malignant glioma.
M. Siegelin, E. Schneider, M. Westhoff, C. Wirtz +1 more
2019Seminars in Cancer Biology48 citations
Semantic Scholar
Dual metabolic reprogramming by ONC201/TIC10 and 2-Deoxyglucose induces energy depletion and synergistic anti-cancer activity in glioblastoma
M. Pruss, A. Dwucet, Mine Tanriover, M. Hlavac +7 more
2020British Journal of Cancer47 citations Open access
Semantic Scholar
Cancer stem cells: The potential role of autophagy, proteolysis, and cathepsins in glioblastoma stem cells
J. Bischof, M. Westhoff, J. Wagner, M. Halatsch +4 more
2017Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine47 citations Open access
Semantic Scholar
Fluorescence guided surgery by 5-ALA and intraoperative MRI in high grade glioma: a systematic review
J. Coburger, C. Wirtz
2018Journal of Neuro-Oncology44 citations
Semantic Scholar
Intraoperative MRI-Guided Resection Is Not Superior to 5-Aminolevulinic Acid Guidance in Newly Diagnosed Glioblastoma: A Prospective Controlled Multicenter Clinical Trial
C. Roder, W. Stummer, J. Coburger, Moritz Scherer +26 more
2023Journal of Clinical Oncology43 citations Open access
Semantic Scholar
Impact of extent of resection and recurrent surgery on clinical outcome and overall survival in a consecutive series of 170 patients for glioblastoma in intraoperative high field magnetic resonance imaging.
J. Coburger, C. Wirtz, R. König
2017Journal of Neurosurgical Sciences43 citations
Semantic Scholar
Histopathological Insights on Imaging Results of Intraoperative Magnetic Resonance Imaging, 5-Aminolevulinic Acid, and Intraoperative Ultrasound in Glioblastoma Surgery
J. Coburger, A. Scheuerle, A. Paľa, D. Thal +2 more
2017Neurosurgery41 citations
Semantic Scholar
Surgery for Diffuse WHO Grade II Gliomas: Volumetric Analysis of a Multicenter Retrospective Cohort From the German Study Group for Intraoperative Magnetic Resonance Imaging.
Moritz Scherer, H. Ahmeti, C. Roder, F. Gessler +9 more
2019Neurosurgery40 citations
Semantic Scholar
Vacquinol-1 inducible cell death in glioblastoma multiforme is counter regulated by TRPM7 activity induced by exogenous ATP
P. Sander, H. Mostafa, Ayman Soboh, Julian M. Schneider +6 more
2017OncoTarget37 citations Open access
Semantic Scholar
Anti-glioma Activity of Dapsone and Its Enhancement by Synthetic Chemical Modification
G. Karpel-Massler, R. Kast, M. Siegelin, A. Dwucet +6 more
2017Neurochemical Research34 citations
Semantic Scholar
The Value of Intraoperative Magnetic Resonance Imaging in Endoscopic and Microsurgical Transsphenoidal Pituitary Adenoma Resection.
A. Paľa, A. Knoll, C. Brand, G. Etzrodt-Walter +3 more
2017World Neurosurgery33 citations
Semantic Scholar
3D Cellular Architecture Modulates Tyrosine Kinase Activity, Thereby Switching CD95-Mediated Apoptosis to Survival.
Gülce S. Gülcüler Balta, C. Monzel, S. Kleber, Joël Beaudouin +9 more
2019Cell Reports31 citations Open access
Semantic Scholar
Quality of Life After Treatment of Unruptured Intracranial Aneurysms.
A. Paľa, Alexandra Pawlikowski, C. Brand, B. Schmitz +3 more
2019World Neurosurgery30 citations
Semantic Scholar
Bcl‐2/Bcl‐xL inhibition predominantly synergistically enhances the anti‐neoplastic activity of a low‐dose CUSP9 repurposed drug regime against glioblastoma
M. Halatsch, R. Kast, A. Dwucet, M. Hlavac +6 more
2019British Journal of Pharmacology29 citations Open access
Semantic Scholar
HOXA7, HOXA9, and HOXA10 are differentially expressed in clival and sacral chordomas
Daniela J. Jäger, T. Barth, S. Brüderlein, A. Scheuerle +10 more
2017Scientific Reports29 citations Open access
Semantic Scholar
The patients’ view: impact of the extent of resection, intraoperative imaging, and awake surgery on health-related quality of life in high-grade glioma patients—results of a multicenter cross-sectional study
K. Nickel, M. Renovanz, J. König, L. Stöckelmaier +9 more
2017Neurosurgical review29 citations
Semantic Scholar
Supportive Care Needs in Glioma Patients and Their Caregivers in Clinical Practice: Results of a Multicenter Cross-Sectional Study
M. Renovanz, D. Maurer, H. Lahr, E. Weimann +5 more
2018Frontiers in Neurology27 citations Open access
Semantic Scholar
Ten years' experience with intraoperative MRI-assisted transsphenoidal pituitary surgery.
M. Hlavac, A. Knoll, B. Mayer, M. Braun +5 more
2020Neurosurgical Focus25 citations Open access
Semantic Scholar
To treat or not to treat? A retrospective multicenter assessment of survival in patients with IDH-mutant low-grade glioma based on adjuvant treatment.
A. Paľa, J. Coburger, Moritz Scherer, H. Ahmeti +10 more
2020Journal of Neurosurgery23 citations
Semantic Scholar
Intraoperative MRI in transsphenoidal resection of invasive pituitary macroadenomas
M. Hlavac, A. Knoll, G. Etzrodt-Walter, F. Sommer +4 more
2019Neurosurgical review23 citations
Semantic Scholar
Photodynamic Therapy Combined with Bcl-2/Bcl-xL Inhibition Increases the Noxa/Mcl-1 Ratio Independent of Usp9X and Synergistically Enhances Apoptosis in Glioblastoma
Carolin Golla, Mayas Bilal, A. Dwucet, N. Bader +10 more
2021Cancers21 citations Open access
Semantic Scholar
Sodium Fluorescein-Guided Surgery in Peripheral Nerve Sheath Tumors: First Experience in 10 Cases of Schwannoma.
M. Pedro, A. Eissler, J. Schmidberger, W. Kratzer +3 more
2019World Neurosurgery21 citations
Semantic Scholar
Mechanisms, Treatment, and Patient Outcome of Iatrogenic Injury to the Brachial Plexus-A Retrospective Single-Center Study.
N. Dengler, G. Antoniadis, Brigitta Grolik, C. Wirtz +2 more
2017World Neurosurgery21 citations
Semantic Scholar
Cathepsin G-mediated proteolytic degradation of MHC class I molecules to facilitate immune detection of human glioblastoma cells
D. Palesch, J. Wagner, Annika Meid, N. Molenda +10 more
2016Cancer Immunology and Immunotherapy21 citations
Semantic Scholar
The influence of nimodipine and vasopressors on outcome in patients with delayed cerebral ischemia after spontaneous subarachnoid hemorrhage.
A. Paľa, Juliane Schick, M. Klein, B. Mayer +4 more
2020Journal of Neurosurgery20 citations
Semantic Scholar
Therapy for Recurrent High-Grade Gliomas: Results of a Prospective Multicenter Study on Health-Related Quality of Life.
L. Stöckelmaier, M. Renovanz, J. König, K. Nickel +7 more
2017World Neurosurgery20 citations
Semantic Scholar
Health-related quality of life and distress in elderly vs. younger patients with high-grade glioma—results of a multicenter study
M. Renovanz, A. Hickmann, M. Nadji-Ohl, N. Keric +5 more
2020Supportive Care in Cancer19 citations Open access
Semantic Scholar
The evolution of invasive cerebral vasospasm treatment in patients with spontaneous subarachnoid hemorrhage and delayed cerebral ischemia—continuous selective intracarotid nimodipine therapy in awake patients without sedation
A. Paľa, Max Schneider, C. Brand, M. Pedro +6 more
2019Neurosurgical review19 citations
Semantic Scholar
Response to Cervical Medial Branch Blocks In Patients with Cervicogenic Vertigo.
Tim Hahn, M. Halatsch, C. Wirtz, S. Klessinger
2018Pain Physician18 citations Open access
Semantic Scholar
Contemporary use of intraoperative imaging in glioma surgery: A survey among EANS members.
J. Coburger, A. Nabavi, R. König, C. Wirtz +1 more
2017Clinical neurology and neurosurgery (Dutch-Flemish ed. Print)18 citations
Semantic Scholar
Combined inhibition of RAC1 and Bcl-2/Bcl-xL synergistically induces glioblastoma cell death through down-regulation of the Usp9X/Mcl-1 axis
M. Hlavac, A. Dwucet, R. Kast, J. Engelke +6 more
2019Cellular Oncology17 citations Open access
Semantic Scholar
Is MGMT promoter methylation to be considered in the decision making for recurrent surgery in glioblastoma patients?
A. Paľa, A. Schmitz, A. Knoll, Max Schneider +4 more
2018Clinical neurology and neurosurgery (Dutch-Flemish ed. Print)16 citations
Semantic Scholar
Outcome After Decompressive Craniectomy in Different Pathologies.
T. Kapapa, C. Brand, C. Wirtz, D. Woischneck
2016World Neurosurgery16 citations
Semantic Scholar
Intraoperative Sodium-Fluorescence Imaging in Peripheral Nerve Sheath Tumors (PNST)—A New Additional Promising Diagnostic Tool
M. Pedro, N. Grübel, G. Durner, A. Paľa +2 more
2021Frontiers in Oncology14 citations Open access
Semantic Scholar
Diagnostic accuracy of intraoperative perfusion-weighted MRI and 5-aminolevulinic acid in relation to contrast-enhanced intraoperative MRI and 11C-methionine positron emission tomography in resection of glioblastoma: a prospective study
A. Paľa, S. Reske, Nina Eberhardt, A. Scheuerle +5 more
2018Neurosurgical review14 citations
Semantic Scholar
Activation of Cytotoxic Natural Killer Cells After Aneurysmal Subarachnoid Hemorrhage.
D. Spitzer, Nina J. Spitzer, Monika Deininger, C. Wirtz +3 more
2017World Neurosurgery14 citations
Semantic Scholar
Exogenous cathepsin G upregulates cell surface MHC class I molecules on immune and glioblastoma cells
M. Giese, Nadine Turiello, N. Molenda, D. Palesch +9 more
2016OncoTarget14 citations Open access
Semantic Scholar
Towards automated correction of brain shift using deep deformable magnetic resonance imaging-intraoperative ultrasound (MRI-iUS) registration
Ramy A. Zeineldin, M. E. Karar, J. Coburger, C. Wirtz +2 more
202013 citations Open access
Semantic Scholar
Clipping as re-treatment strategy after treatment of a cerebral aneurysm with the Woven EndoBridge embolization device: case report.
G. Durner, Y. Özpeynirci, B. Schmitz, C. Wirtz +2 more
2019Journal of Neurosurgery13 citations Open access
Semantic Scholar
Augmented Reality–Assisted versus Freehand Ventriculostomy in a Head Model
Max Schneider, Christian Kunz, C. Wirtz, F. Mathis-Ullrich +2 more
2022Central European Neurosurgery12 citations
Semantic Scholar
Is There an Indication for Intraoperative MRI in Subtotal Resection of Glioblastoma? A Multicenter Retrospective Comparative Analysis.
J. Coburger, Javier Segovia von Riehm, O. Ganslandt, C. Wirtz +1 more
2017World Neurosurgery12 citations
Semantic Scholar
Eloquent Lower Grade Gliomas, a Highly Vulnerable Cohort: Assessment of Patients’ Functional Outcome After Surgery Based on the LoG-Glio Registry
J. Coburger, J. Onken, S. Rueckriegel, C. von der Brelie +19 more
2022Frontiers in Oncology11 citations Open access
Semantic Scholar
Evaluation of a Navigated 3D Ultrasound Integration for Brain Tumor Surgery: First Results of an Ongoing Prospective Study
Danilo Aleo, Ziad Elshaer, A. Pfnür, P. Schuler +4 more
2022Current Oncology10 citations Open access
Semantic Scholar
iRegNet: Non-rigid Registration of MRI to Interventional US for Brain-Shift Compensation using Convolutional Neural Networks
Ramy A. Zeineldin, M. E. Karar, Ziad Elshaer, Markus Schmidhammer +4 more
2021IEEE Access10 citations Open access
Semantic Scholar
Sodium- Fluorescein as intraoperative visualization tool during peripheral nerve biopsies.
M. Pedro, A. Eissler, A. Scheuerle, J. Schmidberger +4 more
2019World Neurosurgery10 citations
Semantic Scholar
Do Complication Rates of Ventricular Drain Placement Differ between Twist Drill and Burr Hole in Acute Hydrocephalus?
C. Brand, A. Paľa, W. Kielhorn, C. Wirtz +1 more
2019Central European Neurosurgery10 citations
Semantic Scholar

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J. Coburger×23
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J. Coburger — researcher profile on SciRah
A. Paľa×18
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A. Paľa — researcher profile on SciRah
R. König×11
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R. König — researcher profile on SciRah
M. Hlavac×9
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G. Karpel-Massler×7

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M. Siegelin — researcher profile on SciRah

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B. Schmitz — researcher profile on SciRah

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T. Kapapa — researcher profile on SciRah

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A. Dwucet — researcher profile on SciRah