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B. Edgar · SciRah

Researcher profile · Semantic Scholar

B. Edgar

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B. Edgar — researcher profile on SciRah

h-index: 63
Works: 142
Citations: 20K

Most-cited papers

Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut
Huaqi Jiang, Parthive H. Patel, Alexander Kohlmaier, Marc Grenley +2 more
2009Cell1,035 citations Open access
Semantic Scholar
EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila
Huaqi Jiang, Marc Grenley, Maria-Jose Bravo, Rachel Blumhagen +1 more
2010Cell Stem Cell480 citations Open access
Semantic Scholar
How flies get their size: genetics meets physiology
B. Edgar
2006Nature reviews genetics452 citations
Semantic Scholar
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development
S. Grewal, Ling Li, A. Orian, R. Eisenman +1 more
2005Nature Cell Biology397 citations
Semantic Scholar
Filling out the Hippo pathway
Leslie J. Saucedo, B. Edgar
2007Nature reviews. Molecular cell biology370 citations
Semantic Scholar
From cell structure to transcription: Hippo forges a new path.
B. Edgar
2006Cell353 citations Open access
Semantic Scholar
Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth
B. Edgar, N. Zielke, C. Gutierrez
2014Nature reviews. Molecular cell biology336 citations
Semantic Scholar
The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration
R. L. Shaw, Alexander Kohlmaier, Cédric Polesello, C. Veelken +2 more
2010Development328 citations Open access
Semantic Scholar
EGFR signaling regulates the proliferation of Drosophila adult midgut progenitors
Huaqi Jiang, B. Edgar
2009Development294 citations Open access
Semantic Scholar
Fly-FUCCI: A versatile tool for studying cell proliferation in complex tissues.
N. Zielke, J. Korzelius, M. van Straaten, Katharina Bender +4 more
2014Cell Reports266 citations Open access
Semantic Scholar
Regional Cell-Specific Transcriptome Mapping Reveals Regulatory Complexity in the Adult Drosophila Midgut.
Devanjali Dutta, A. Dobson, Philip Houtz, C. Gläßer +5 more
2015Cell Reports239 citations Open access
Semantic Scholar
Mechanisms controlling cell cycle exit upon terminal differentiation.
Laura A. Buttitta, B. Edgar
2007Current Opinion in Cell Biology210 citations Open access
Semantic Scholar
Intestinal stem cells in the adult Drosophila midgut
Huaqi Jiang, B. Edgar
2011Experimental Cell Research186 citations Open access
Semantic Scholar
Intestinal stem cell function in Drosophila and Mice
Huaqi Jiang, B. Edgar
2012Current Opinion in Genetics and Development167 citations Open access
Semantic Scholar
Niche Appropriation by Drosophila Intestinal Stem Cell Tumors
Parthive H. Patel, Devanjali Dutta, B. Edgar
2015Nature Cell Biology156 citations Open access
Semantic Scholar
FUCCI sensors: powerful new tools for analysis of cell proliferation
N. Zielke, B. Edgar
2015Wiley Interdisciplinary Reviews: Developmental Biology155 citations Open access
Semantic Scholar
Polyploidy in tissue homeostasis and regeneration
J. Ovrebø, B. Edgar
2018Development152 citations Open access
Semantic Scholar
TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease
Tao Wang, Uyen Lao, B. Edgar
2009Journal of Cell Biology146 citations Open access
Semantic Scholar
Control of Drosophila endocycles by E2F and CRL4Cdt2
N. Zielke, Kerry J. Kim, Vuong Tran, Shusaku Shibutani +10 more
2011Nature145 citations Open access
Semantic Scholar
EGFR/Ras Signaling Controls Drosophila Intestinal Stem Cell Proliferation via Capicua-Regulated Genes
Yinhua Jin, N. Ha, M. Forés, Jin-Yi Xiang +4 more
2015PLoS Genetics136 citations Open access
Semantic Scholar
Endoreplication
N. Zielke, B. Edgar, M. DePamphilis
2013Cold Spring Harbor Perspectives in Biology133 citations Open access
Semantic Scholar
Intrinsic negative cell cycle regulation provided by PIP box- and Cul4Cdt2-mediated destruction of E2f1 during S phase
Shusaku Shibutani, A. de la Cruz, Vuong Tran, W. J. Turbyfill +3 more
2008Developmental Cell131 citations Open access
Semantic Scholar
Fitness trade-offs incurred by ovary-to-gut steroid signaling in Drosophila
Sara M Ahmed, J. Maldera, D. Krunic, G. Paiva-Silva +3 more
2020Nature128 citations Open access
Semantic Scholar
Escargot maintains stemness and suppresses differentiation in Drosophila intestinal stem cells
J. Korzelius, S. K. Naumann, Mariano A. Loza-Coll, J. Chan +7 more
2014EMBO Journal124 citations Open access
Semantic Scholar
A double-assurance mechanism controls cell cycle exit upon terminal differentiation in Drosophila.
Laura A. Buttitta, Alexia J. Katzaroff, Carissa L. Perez, A. de la Cruz +1 more
2007Developmental Cell114 citations Open access
Semantic Scholar
EGFR-dependent TOR-independent endocycles support Drosophila gut epithelial regeneration
Jin-Yi Xiang, Jennifer L. Bandura, Peng Zhang, Yinhua Jin +2 more
2017Nature Communications109 citations Open access
Semantic Scholar
Drosophila TIF-IA is required for ribosome synthesis and cell growth and is regulated by the TOR pathway
S. Grewal, Justin Evans, B. Edgar
2007Journal of Cell Biology97 citations Open access
Semantic Scholar
The Drosophila mitochondrial ribosomal protein mRpL12 is required for Cyclin D/Cdk4‐driven growth
Christian Frei, M. Galloni, E. Hafen, B. Edgar
2005EMBO Journal81 citations Open access
Semantic Scholar
Dpp/Gbb signaling is required for normal intestinal regeneration during infection.
Jun Zhou, Sebastian Florescu, Anna-Lisa Boettcher, Li-Chao Luo +5 more
2015Developmental Biology75 citations Open access
Semantic Scholar
An SH3PX1-dependent endocytosis/autophagy network restrains intestinal stem cell proliferation by counteracting EGFR/ERK signaling
Peng Zhang, A. Holowatyj, T. Roy, S. M. Pronovost +4 more
2019Developmental Cell72 citations Open access
Semantic Scholar
Damage sensing by a Nox-Ask1-MKK3-p38 signaling pathway mediates regeneration in the adult Drosophila midgut
Parthive H. Patel, Clothilde Pénalva, Michael Kardorff, Marianne Roca +4 more
2019Nature Communications71 citations Open access
Semantic Scholar
Suppression of polyglutamine protein toxicity by co-expression of a heat-shock protein 40 and a heat-shock protein 110
Y. Kuo, S. Ren, Uyen Lao, B. Edgar +1 more
2013Cell Death and Disease71 citations Open access
Semantic Scholar
Nutritional control of gene expression in Drosophila larvae via TOR, Myc and a novel cis-regulatory element
Ling Li, B. Edgar, S. Grewal
2010BMC Cell Biology71 citations Open access
Semantic Scholar
The Transcriptional Repressor dMnt Is a Regulator of Growth in Drosophila melanogaster
Lenora W. M. Loo, J. Secombe, J. T. Little, L. Carlos +5 more
2005Molecular and Cellular Biology62 citations Open access
Semantic Scholar
A robust cell cycle control mechanism limits E2F-induced proliferation of terminally differentiated cells in vivo
Laura A. Buttitta, Alexia J. Katzaroff, B. Edgar
2010Journal of Cell Biology57 citations Open access
Semantic Scholar
Enhanced expression of thioredoxin‐interacting‐protein regulates oxidative DNA damage and aging
T. Oberacker, J. Bajorat, S. Ziola, Anne E. Schroeder +6 more
2018FEBS Letters55 citations Open access
Semantic Scholar
Insect Gut Regeneration.
Peng Zhang, B. Edgar
2021Cold Spring Harbor Perspectives in Biology52 citations Open access
Semantic Scholar
ATF3 acts as a rheostat to control JNK signalling during intestinal regeneration
Jun Zhou, B. Edgar, M. Boutros
2017Nature Communications52 citations Open access
Semantic Scholar
Intestinal Stem Cell Pool Regulation in Drosophila
Yinhua Jin, Parthive H. Patel, Alexander Kohlmaier, Bojana Pavlović +2 more
2017Stem Cell Reports50 citations Open access
Semantic Scholar
Proliferative control in Drosophila stem cells
Alexander Kohlmaier, B. Edgar
2008Current Opinion in Cell Biology49 citations Open access
Semantic Scholar
RNA expression profiling from FACS-isolated cells of the Drosophila intestine.
Devanjali Dutta, Jin-Yi Xiang, B. Edgar
2013Current protocols in stem cell biology48 citations
Semantic Scholar
In Vivo Analysis of Centromeric Proteins Reveals a Stem Cell-Specific Asymmetry and an Essential Role in Differentiated, Non-proliferating Cells.
Ana García Del Arco, B. Edgar, S. Erhardt
2018Cell Reports47 citations Open access
Semantic Scholar
Genomic analysis of COP9 signalosome function in Drosophila melanogaster reveals a role in temporal regulation of gene expression
E. Oron, T. Tuller, Ling Li, Nina Rozovsky +6 more
2007Molecular Systems Biology47 citations Open access
Semantic Scholar
Rheb-TOR signaling promotes protein synthesis, but not glucose or amino acid import, in Drosophila
D. Hall, S. Grewal, A. de la Cruz, B. Edgar
2007BMC Biology46 citations Open access
Semantic Scholar
EGFR Signaling Activates Intestinal Stem Cells by Promoting Mitochondrial Biogenesis and β-oxidation
Chen-Ge Zhang, Yinhua Jin, M. Marchetti, M. Lewis +2 more
2022Current Biology45 citations Open access
Semantic Scholar
Egfr/Ras signaling regulates DE-cadherin/Shotgun localization to control vein morphogenesis in the Drosophila wing.
David D. O'Keefe, D. Prober, Patrick S Moyle, W. Rickoll +1 more
2007Developmental Biology41 citations Open access
Semantic Scholar
Remodelling of oxygen-transporting tracheoles drives intestinal regeneration and tumorigenesis in Drosophila
Vasilia Tamamouna, M. M. Rahman, M. Petersson, Irini Charalambous +6 more
2021Nature Cell Biology39 citations Open access
Semantic Scholar
Brk regulates wing disc growth in part via repression of Myc expression
N. Doumpas, M. Ruiz-Romero, E. Blanco, B. Edgar +2 more
2013EMBO Reports39 citations Open access
Semantic Scholar
Flow cytometric analysis of Drosophila cells.
A. de la Cruz, B. Edgar
2008Methods in molecular biology39 citations
Semantic Scholar
Rap1 maintains adhesion between cells to affect Egfr signaling and planar cell polarity in Drosophila
David D. O'Keefe, Eduardo Gonzalez-Niño, Micheal Burnett, Layne Dylla +5 more
2009Developmental Biology37 citations Open access
Semantic Scholar

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Parthive H. Patel×5
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A. de la Cruz×4

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