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G. Várady · SciRah

Researcher profile · Semantic Scholar

G. Várady

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G. Várady — researcher profile on SciRah

h-index: 25
Works: 81
Citations: 2,140

Most-cited papers

High-affinity interaction of tyrosine kinase inhibitors with the ABCG2 multidrug transporter.
Csilla Ozvegy-Laczka, T. Hegedűs, G. Várady, O. Ujhelly +6 more
2004Molecular Pharmacology363 citations Open access
Semantic Scholar
Multidrug transporter ABCG2 prevents tumor cell death induced by the epidermal growth factor receptor inhibitor Iressa (ZD1839, Gefitinib).
N. Elkind, Z. Szentpétery, Á. Apáti, Csilla Ozvegy-Laczka +9 more
2005Cancer Research227 citations Open access
Semantic Scholar
Function-dependent Conformational Changes of the ABCG2 Multidrug Transporter Modify Its Interaction with a Monoclonal Antibody on the Cell Surface*
C. Özvegy-Laczka, G. Várady, Gabriella Koblos, O. Ujhelly +7 more
2005Journal of Biological Chemistry97 citations Open access
Semantic Scholar
High level functional expression of the ABCG2 multidrug transporter in undifferentiated human embryonic stem cells.
Á. Apáti, T. Orbán, N. Varga, A. Németh +10 more
2008Biochimica et Biophysica Acta92 citations Open access
Semantic Scholar
Interaction of the EGFR inhibitors gefitinib, vandetanib, pelitinib and neratinib with the ABCG2 multidrug transporter: implications for the emergence and reversal of cancer drug resistance.
C. Hegedüs, K. Truta-Feles, G. Antalffy, G. Várady +8 more
2012Biochemical Pharmacology77 citations
Semantic Scholar
Applying a “Double‐Feature” Promoter to Identify Cardiomyocytes Differentiated from Human Embryonic Stem Cells Following Transposon‐Based Gene Delivery
T. Orbán, Á. Apáti, A. Németh, N. Varga +14 more
2009Stem Cells60 citations Open access
Semantic Scholar
Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1
I. Patik, Virág Székely, Orsolya Német, Áron Szepesi +5 more
2018Scientific Reports55 citations Open access
Semantic Scholar
Reliable transgene-independent method for determining Sleeping Beauty transposon copy numbers
Orsolya Kolacsek, V. Krízsik, Anita Schamberger, Zsuzsa Erdei +7 more
2011Mobile DNA49 citations Open access
Semantic Scholar
Cell surface membrane proteins as personalized biomarkers: where we stand and where we are headed.
G. Várady, J. Cserepes, A. Németh, E. Szabó +1 more
2013Biomarkers in Medicine48 citations Open access
Semantic Scholar
Interaction with the 5D3 Monoclonal Antibody Is Regulated by Intramolecular Rearrangements but Not by Covalent Dimer Formation of the Human ABCG2 Multidrug Transporter*
C. Özvegy-Laczka, Rozália Laczkó, C. Hegedüs, T. Litman +7 more
2008Journal of Biological Chemistry48 citations Open access
Semantic Scholar
Functional Expression of the 11 Human Organic Anion Transporting Polypeptides in Insect Cells Reveals that Sodium Fluorescein is a General OATP Substrate
I. Patik, Daniella Kovacsics, Orsolya Német, Melinda Gera +5 more
2015Biochemical Pharmacology44 citations Open access
Semantic Scholar
Interactions of Potential Anti-COVID-19 Compounds with Multispecific ABC and OATP Drug Transporters
Á. Telbisz, C. Ambrus, O. Mózner, E. Szabó +4 more
2021Pharmaceutics43 citations Open access
Semantic Scholar
Expression Levels of the ABCG2 Multidrug Transporter in Human Erythrocytes Correspond to Pharmacologically Relevant Genetic Variations
Ildikó Kasza, G. Várady, H. Andrikovics, Magdalena Koszarska +5 more
2012PLoS ONE43 citations Open access
Semantic Scholar
Application of a Human Multidrug Transporter (ABCG2) Variant as Selectable Marker in Gene Transfer to Progenitor Cells
O. Ujhelly, Csilla Özvegy, G. Várady, J. Cervenak +8 more
2003Human Gene Therapy43 citations
Semantic Scholar
Antibody binding shift assay for rapid screening of drug interactions with the human ABCG2 multidrug transporter.
Á. Telbisz, C. Hegedüs, C. Özvegy-Laczka, K. Goda +6 more
2012European Journal of Pharmaceutical Sciences42 citations Open access
Semantic Scholar
Decreased calcium pump expression in human erythrocytes is connected to a minor haplotype in the ATP2B4 gene.
Boglárka Zámbó, G. Várady, R. Padányi, E. Szabó +4 more
2017Cell Calcium41 citations Open access
Semantic Scholar
In Vitro Characterization of Human Mesenchymal Stem Cells Isolated from Different Tissues with a Potential to Promote Complex Bone Regeneration
Áron Szepesi, Zsolt Matula, Anna Szigeti, G. Várady +5 more
2016Stem Cells International38 citations Open access
Semantic Scholar
Evaluation of ABCG2 Expression in Human Embryonic Stem Cells: Crossing the Same River Twice?
B. Sarkadi, T. Orbán, G. Szakács, G. Várady +5 more
2010Stem Cells33 citations
Semantic Scholar
Inconsistencies in the red blood cell membrane proteome analysis: generation of a database for research and diagnostic applications
T. Hegedűs, P. M. Chaubey, G. Várady, E. Szabó +5 more
2015Database J. Biol. Databases Curation32 citations Open access
Semantic Scholar
Clinically relevant mutations in the ABCG2 transporter uncovered by genetic analysis linked to erythrocyte membrane protein expression
Boglárka Zámbó, Zsuzsa Bartos, O. Mózner, E. Szabó +7 more
2018Scientific Reports31 citations Open access
Semantic Scholar
A novel fluorescence‐based functional assay for human OATP1A2 and OATP1C1 identifies interaction between third‐generation P‐gp inhibitors and OATP1A2
Éva Bakos, Orsolya Német, I. Patik, Nóra Kucsma +3 more
2019The FEBS Journal30 citations
Semantic Scholar
Expression pattern of the human ABC transporters in pluripotent embryonic stem cells and in their derivatives
Zsuzsa Erdei, Reka Lorincz, Kornélia Szebényi, Adrienn Péntek +7 more
2014Cytometry. Part B, Clinical cytometry30 citations Open access
Semantic Scholar
Dynamic ABCG2 expression in human embryonic stem cells provides the basis for stress response
Zsuzsa Erdei, B. Sarkadi, A. Brózik, Kornélia Szebényi +5 more
2013European Biophysics Journal29 citations
Semantic Scholar
Multidrug Transporter ABCG 2 Prevents Tumor Cell Death Induced by the Epidermal Growth Factor Receptor Inhibitor Iressa ( ZD 1839 , Gefitinib )
N. Elkind, Z. Szentpétery, Á. Apáti, C. Özvegy-Laczka +9 more
200529 citations
Semantic Scholar
Alterations in erythrocyte membrane transporter expression levels in type 2 diabetic patients
E. Szabó, A. Kulin, L. Koranyi, B. Literáti-Nagy +4 more
2021Scientific Reports25 citations Open access
Semantic Scholar
Cellular expression and function of naturally occurring variants of the human ABCG2 multidrug transporter
Boglárka Zámbó, O. Mózner, Zsuzsa Bartos, György Török +5 more
2019Cellular and Molecular Life Sciences25 citations Open access
Semantic Scholar
Application of fluorescent dye substrates for functional characterization of ABC multidrug transporters at a single cell level
Zsuzsanna Nerada, Z. Hegyi, Áron Szepesi, S. Tóth +6 more
2016Cytometry Part A25 citations Open access
Semantic Scholar
SPECIFIC REPLANT DISEASE REDUCED BY PGPR RHIZOBACTERIA ON APPLE SEEDLINGS
B. Biró, K. Magyar, G. Várady, M. Kecskés
199825 citations
Semantic Scholar
Unshielding multidrug resistant cancer through selective iron depletion of P-glycoprotein expressing cells.
Mihály Cserepes, Dóra Türk, S. Tóth, Veronika F. S. Pape +11 more
2019Cancer Research24 citations
Semantic Scholar
Alterations of membrane protein expression in red blood cells of Alzheimer's disease patients
G. Várady, E. Szabó, Á. Fehér, A. Németh +4 more
2015Alzheimer's & Dementia24 citations Open access
Semantic Scholar
Identification of Extracellular Segments by Mass Spectrometry Improves Topology Prediction of Transmembrane Proteins
T. Langó, G. Róna, É. Hunyadi-Gulyás, Lilla Turiák +8 more
2017Scientific Reports21 citations Open access
Semantic Scholar
Stimulus-induced expression of the ABCG2 multidrug transporter in HepG2 hepatocarcinoma model cells involves the ERK1/2 cascade and alternative promoters.
Hugues de Boussac, T. Orbán, G. Várady, B. Tihanyi +5 more
2012Biochemical and Biophysical Research Communications - BBRC21 citations
Semantic Scholar
Screening the Expression of ABCB6 in Erythrocytes Reveals an Unexpectedly High Frequency of Lan Mutations in Healthy Individuals
Magdalena Koszarska, Nóra Kucsma, K. Kiss, G. Várady +10 more
2014PLoS ONE20 citations Open access
Semantic Scholar
Covalently modified carboxyl side chains on cell surface leads to a novel method toward topology analysis of transmembrane proteins
Anna Müller, T. Langó, Lilla Turiák, A. Ács +4 more
2019Scientific Reports19 citations Open access
Semantic Scholar
Establishment and Characterization of a Brca1−/−, p53−/− Mouse Mammary Tumor Cell Line
Lilla Hámori, Gyöngyi Kudlik, Kornélia Szebényi, Nóra Kucsma +8 more
2020International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
TTRAP Is a Novel Component of the Non-Canonical TRAF6-TAK1 TGF-β Signaling Pathway
G. Várady, B. Sarkadi, K. Fátyol
2011PLoS ONE16 citations Open access
Semantic Scholar
Precision-engineered reporter cell lines reveal ABCG2 regulation in live lung cancer cells.
Daniella Kovacsics, A. Brózik, B. Tihanyi, Zsolt Matula +11 more
2020Biochemical Pharmacology15 citations Open access
Semantic Scholar
A new fluorescent dye accumulation assay for parallel measurements of the ABCG2, ABCB1 and ABCC1 multidrug transporter functions
E. Szabó, Dóra Türk, Á. Telbisz, Nóra Kucsma +5 more
2018PLoS ONE15 citations Open access
Semantic Scholar
Co-Transmission of Alpha-Synuclein and TPPP/p25 Inhibits Their Proteolytic Degradation in Human Cell Models
A. Lehotzky, J. Olah, J. Fekete, Tibor Szénási +4 more
2021Frontiers in Molecular Biosciences14 citations Open access
Semantic Scholar
Signaling Via PI3K/FOXO1A Pathway Modulates Formation and Survival of Human Embryonic Stem Cell-Derived Endothelial Cells
B. Merkely, E. Gara, Zsuzsanna Lendvai, J. Skopál +9 more
2015Stem Cells and Development14 citations Open access
Semantic Scholar
Generation of multidrug resistant human tissues by overexpression of the ABCG2 multidrug transporter in embryonic stem cells
Zsuzsa Erdei, Anita Schamberger, György Török, Kornélia Szebényi +5 more
2018PLoS ONE13 citations Open access
Semantic Scholar
ABCG2 Is a Selectable Marker for Enhanced Multilineage Differentiation Potential in Periodontal Ligament Stem Cells
Áron Szepesi, Zsolt Matula, Anna Szigeti, G. Várady +4 more
2015Stem Cells and Development13 citations Open access
Semantic Scholar
Potential role of the ABCG2-Q141K polymorphism in type 2 diabetes
E. Szabó, A. Kulin, O. Mózner, L. Koranyi +5 more
2021PLoS ONE11 citations Open access
Semantic Scholar
Characterization of the Proprotein Convertase-Mediated Processing of Peroxidasin and Peroxidasin-like Protein
Hajnal A. Kovács, E. Lázár, G. Várady, Gábor Sirokmány +1 more
2021Antioxidants10 citations Open access
Semantic Scholar
Generation of multiple iPSC clones from a male schizophrenia patient carrying de novo mutations in genes KHSRP, LRRC7, and KIR2DL1, and his parents.
E. Hathy, E. Szabó, K. Vincze, I. Haltrich +7 more
2020Stem Cell Research10 citations Open access
Semantic Scholar
Influence of the measles virus on the proliferation and protein synthesis of aortic endothelial and smooth muscle cells.
É. Csonka, P. Bayer, K. Buki, G. Várady
1990Acta microbiologica Hungarica10 citations
Semantic Scholar
Functional characterization of the ABCG2 5' non-coding exon variants: Stem cell specificity, translation efficiency and the influence of drug selection.
Sára Sándor, Theodora Jordanidisz, Anita Schamberger, G. Várady +4 more
2016Biochimica et Biophysica Acta9 citations Open access
Semantic Scholar
Genetic polymorphisms and decreased protein expression of ABCG2 urate transporters are associated with susceptibility to gout, disease severity and renal-overload hyperuricemia
M. Pálinkás, E. Szabó, A. Kulin, O. Mózner +8 more
2022Clinical and Experimental Medicine (Testo stampato)8 citations Open access
Semantic Scholar
The clinical evaluation of Grandaxin used in the treatment of outpatients (a multicentric study).
G. Várady, K. Bolla, J. Sebo
1975Therapia Hungarica8 citations
Semantic Scholar
Synthesis and Application of Two-Photon Active Fluorescent Rhodol Dyes for Antibody Conjugation and In Vitro Cell Imaging
Dénes Szepesi Kovács, B. Chiovini, Dalma Müller, E. Tóth +12 more
2023ACS Omega7 citations Open access
Semantic Scholar

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