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A. Adamis · SciRah

Researcher profile · Semantic Scholar

A. Adamis

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A. Adamis — researcher profile on SciRah

h-index: 82
Works: 204
Citations: 32K

Most-cited papers

Pegaptanib for neovascular age-related macular degeneration.
E. Gragoudas, A. Adamis, E. Cunningham, M. Feinsod +1 more
2004New England Journal of Medicine2,273 citations Open access
Semantic Scholar
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
E. Ng, D. Shima, P. Calias, E. Cunningham +2 more
2006Nature reviews. Drug discovery1,515 citations
Semantic Scholar
Ten years of anti-vascular endothelial growth factor therapy
N. Ferrara, A. Adamis
2016Nature reviews. Drug discovery980 citations Open access
Semantic Scholar
Long-term outcomes of ranibizumab therapy for diabetic macular edema: the 36-month results from two phase III trials: RISE and RIDE.
David M. Brown, Q. D. Nguyen, Dennis M. Marcus, David S. Boyer +9 more
2013Ophthalmology (Rochester, Minn.)865 citations Open access
Semantic Scholar
VEGF INHIBITION STUDY IN OCULAR NEOVASCULARIZATION CLINICAL TRIAL GROUP. PEGAPTANIB FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION
E. Gragoudas, A. Adamis, E. Cunningham, M. Feinsod +1 more
2004726 citations
Semantic Scholar
Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury.
K. Nishijima, Y. Ng, L. Zhong, John S. Bradley +7 more
2007American Journal of Pathology722 citations Open access
Semantic Scholar
A phase II randomized double-masked trial of pegaptanib, an anti-vascular endothelial growth factor aptamer, for diabetic macular edema.
E. Cunningham, A. Adamis, M. Altaweel, L. Aiello +7 more
2005Ophthalmology (Rochester, Minn.)603 citations
Semantic Scholar
Sustained benefits from ranibizumab for macular edema following branch retinal vein occlusion: 12-month outcomes of a phase III study.
David M. Brown, P. Campochiaro, R. Bhisitkul, A. Ho +5 more
2011Ophthalmology (Rochester, Minn.)460 citations
Semantic Scholar
VEGF164-mediated Inflammation Is Required for Pathological, but Not Physiological, Ischemia-induced Retinal Neovascularization
S. Ishida, T. Usui, K. Yamashiro, Y. Kaji +11 more
2003Journal of Experimental Medicine438 citations Open access
Semantic Scholar
VEGF164 is proinflammatory in the diabetic retina.
S. Ishida, T. Usui, K. Yamashiro, Y. Kaji +6 more
2003Investigative Ophthalmology and Visual Science398 citations
Semantic Scholar
Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials.
C. Wykoff, Francis M. Abreu, A. Adamis, K. Basu +13 more
2022The Lancet363 citations Open access
Semantic Scholar
THE ROLE OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN OCULAR HEALTH AND DISEASE
A. Adamis, D. Shima
2005Retina351 citations
Semantic Scholar
Inhibition of platelet-derived growth factor B signaling enhances the efficacy of anti-vascular endothelial growth factor therapy in multiple models of ocular neovascularization.
N. Jo, C. Mailhos, M. Ju, Eunice Cheung +5 more
2006American Journal of Pathology350 citations Open access
Semantic Scholar
Immunological mechanisms in the pathogenesis of diabetic retinopathy
A. Adamis, A. J. Berman
2008Seminars in Immunopathology341 citations
Semantic Scholar
Targeting angiogenesis, the underlying disorder in neovascular age-related macular degeneration.
E. Ng, A. Adamis
2005Canadian Journal of Ophthalmology-journal Canadien D Ophtalmologie292 citations
Semantic Scholar
Pegaptanib sodium for neovascular age-related macular degeneration: two-year safety results of the two prospective, multicenter, controlled clinical trials.
D. D'Amico, H. Masonson, Manju Patel, A. Adamis +3 more
2006Ophthalmology (Rochester, Minn.)291 citations
Semantic Scholar
Year 2 efficacy results of 2 randomized controlled clinical trials of pegaptanib for neovascular age-related macular degeneration.
U. Chakravarthy, A. Adamis, E. Cunningham, M. Goldbaum +3 more
2006Ophthalmology (Rochester, Minn.)288 citations
Semantic Scholar
Changes in retinal neovascularization after pegaptanib (Macugen) therapy in diabetic individuals.
A. Adamis, M. Altaweel, N. Bressler, E. Cunningham +6 more
2006Ophthalmology (Rochester, Minn.)255 citations
Semantic Scholar
The Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration: Results from the Randomized Phase 2 Ladder Clinical Trial.
P. Campochiaro, D. Marcus, C. Awh, C. Regillo +11 more
2019Ophthalmology (Rochester, Minn.)254 citations Open access
Semantic Scholar
Archway Randomized Phase 3 Trial of the Port Delivery System With Ranibizumab for Neovascular Age-Related Macular Degeneration.
N. Holekamp, P. Campochiaro, Margaret A. Chang, Daniel Miller +11 more
2021Ophthalmology (Rochester, Minn.)170 citations Open access
Semantic Scholar
Anti‐VEGF Aptamer (Pegaptanib) Therapy for Ocular Vascular Diseases
E. Ng, A. Adamis
2006Annals of the New York Academy of Sciences164 citations
Semantic Scholar
Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice.
L. Zhong, John S. Bradley, W. Schubert, E. Ahmed +4 more
2007Investigative Ophthalmology and Visual Science163 citations Open access
Semantic Scholar
Insulin-like growth factor-I plays a pathogenetic role in diabetic retinopathy.
V. Poulaki, A. Joussen, N. Mitsiades, C. Mitsiades +2 more
2004American Journal of Pathology155 citations Open access
Semantic Scholar
VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2.
T. Usui, S. Ishida, K. Yamashiro, Y. Kaji +9 more
2004Investigative Ophthalmology and Visual Science152 citations
Semantic Scholar
Inhibition of diabetic leukostasis and blood-retinal barrier breakdown with a soluble form of a receptor for advanced glycation end products.
Y. Kaji, T. Usui, S. Ishida, K. Yamashiro +5 more
2007Investigative Ophthalmology and Visual Science146 citations
Semantic Scholar
Targeted disruption of the CD18 or ICAM-1 gene inhibits choroidal neovascularization.
E. Sakurai, Hogara Taguchi, A. Anand, B. Ambati +4 more
2003Investigative Ophthalmology and Visual Science138 citations Open access
Semantic Scholar
Pegaptanib 1-year systemic safety results from a safety-pharmacokinetic trial in patients with neovascular age-related macular degeneration.
R. Apte, M. Modi, H. Masonson, Manju Patel +2 more
2007Ophthalmology (Rochester, Minn.)108 citations
Semantic Scholar
Angiogenesis and ophthalmic disease
A. Adamis, L. Aiello, R. D'Amato
2004Angiogenesis101 citations
Semantic Scholar
Pegaptanib sodium for macular edema secondary to central retinal vein occlusion.
J. Wroblewski, J. A. Wells, A. Adamis, R. Buggage +5 more
2009A M A Archives of Ophthalmology92 citations
Semantic Scholar
Expression and function of receptors for advanced glycation end products in bovine corneal endothelial cells.
Y. Kaji, S. Amano, T. Usui, T. Oshika +7 more
2003Investigative Ophthalmology and Visual Science81 citations
Semantic Scholar
Vascular endothelial growth factor and the potential therapeutic use of pegaptanib (macugen) in diabetic retinopathy.
C. Starita, Manju Patel, B. Katz, A. Adamis
2007Developments in ophthalmology76 citations
Semantic Scholar
Deep Learning Predicts OCT Measures of Diabetic Macular Thickening From Color Fundus Photographs.
F. Arcadu, Fethallah Benmansour, Andreas Maunz, J. Michon +5 more
2019Investigative Ophthalmology and Visual Science67 citations Open access
Semantic Scholar
Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California).
G. Lutty, T. Chan-Ling, D. Phelps, A. Adamis +31 more
2006Molecular Vision67 citations
Semantic Scholar
Preclinical evaluation of the novel small-molecule integrin alpha5beta1 inhibitor JSM6427 in monkey and rabbit models of choroidal neovascularization.
G. Zahn, D. Vossmeyer, Roland Stragies, M. Wills +4 more
2009A M A Archives of Ophthalmology61 citations Open access
Semantic Scholar
Building on the success of anti-vascular endothelial growth factor therapy: a vision for the next decade
A. Adamis, Christopher Brittain, Atul Dandekar, J. Hopkins
2020Eye60 citations Open access
Semantic Scholar
Spontaneous CNV in a novel mutant mouse is associated with early VEGF-A-driven angiogenesis and late-stage focal edema, neural cell loss, and dysfunction.
N. Nagai, Peter Lundh von Leithner, Kanako Izumi-Nagai, Brett M. Hosking +7 more
2014Investigative Ophthalmology and Visual Science58 citations Open access
Semantic Scholar
Ocular Angiogenesis: Vascular Endothelial Growth Factor and Other Factors.
Roman G. Rubio, A. Adamis
2016Developments in ophthalmology53 citations
Semantic Scholar
Molecular biology of choroidal neovascularization.
Ming Lu, A. Adamis
2006Ophthalmology Clinics of North America46 citations
Semantic Scholar
Inhibition of Corneal Neovascularization by Genetic Ablation of CCR2
B. Ambati, A. Joussen, W. Kuziel, A. Adamis +1 more
2003Cornea40 citations
Semantic Scholar
Assessment of the integrin alpha5beta1 antagonist JSM6427 in proliferative vitreoretinopathy using in vitro assays and a rabbit model of retinal detachment.
G. Zahn, K. Volk, G. Lewis, D. Vossmeyer +9 more
2010Investigative Ophthalmology and Visual Science34 citations Open access
Semantic Scholar
Impediments to eye transplantation: ocular viability following optic-nerve transection or enucleation
D. Ellenberg, Jun Shi, Sandeep Jain, Jin-Hong Chang +10 more
2009British Journal of Ophthalmology33 citations Open access
Semantic Scholar
Cost-effectiveness model for neovascular age-related macular degeneration: comparing early and late treatment with pegaptanib sodium based on visual acuity.
J. Javitt, G. Zlateva, S. Earnshaw, A. Pleil +4 more
2008Value in Health26 citations Open access
Semantic Scholar
Simultaneous but not prior inhibition of VEGF165 enhances the efficacy of photodynamic therapy in multiple models of ocular neovascularization.
M. Ju, C. Mailhos, John S. Bradley, T. Dowie +7 more
2008Investigative Ophthalmology and Visual Science24 citations Open access
Semantic Scholar
Inhibitory effect of an antibody to cryptic collagen type IV epitopes on choroidal neovascularization.
N. Jo, M. Ju, K. Nishijima, G. Robinson +3 more
2004Molecular Vision18 citations
Semantic Scholar
Development of the Port Delivery System with ranibizumab for neovascular age-related macular degeneration
A. Adamis, E. de Juan
2022Current Opinion in Ophthalmology15 citations Open access
Semantic Scholar
Rationale of Basic and Cellular Mechanisms Considered in Updating the Staging System for Diabetic Retinal Disease
M. Hartnett, W. Fickweiler, A. Adamis, Michael Brownlee +9 more
2024Ophthalmology Science12 citations Open access
Semantic Scholar
The case for complement and inflammation in AMD: open questions.
N. Karagianni, A. Adamis
2010Advances in Experimental Medicine and Biology12 citations
Semantic Scholar
VEGF–mediated neuroprotection in ischemic retina
D. Shima, K. Nishijima, N. Jo, A. Adamis
200412 citations
Semantic Scholar
Inflammation and retinal disease : complement biology and pathology
John D Lambris, A. Adamis
201011 citations
Semantic Scholar
THE RATIONALE FOR DRUG COMBINATIONS IN AGE-RELATED MACULAR DEGENERATION
A. Adamis
2009Retina11 citations
Semantic Scholar

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