Y. Lien

Most-cited papers

Estrogen action and male fertility: Roles of the sodium/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function
Qingsong Zhou, L. Clarke, Rong Nie, K. Carnes +7 more
2001Proceedings of the National Academy of Sciences of the United States of America215 citations Open access
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Cinacalcet hydrochloride is an effective treatment for secondary hyperparathyroidism in patients with CKD not receiving dialysis.
C. Charytan, J. W. Coburn, M. Chonchol, J. Herman +5 more
2005American Journal of Kidney Diseases155 citations
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Pathogenesis diagnosis and management of paraneoplastic glomerulonephritis
Y. Lien, L. Lai
2010Nature Reviews Nephrology154 citations Open access
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Pathogenesis of renal ischemia/reperfusion injury: lessons from knockout mice.
Y. Lien, L. Lai, A. Silva
2003Life Science147 citations
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Hyponatremia: clinical diagnosis and management.
Y. Lien, J. Shapiro
2007American Journal of Medicine117 citations
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Role of organic osmolytes in myelinolysis. A topographic study in rats after rapid correction of hyponatremia.
Y. Lien
1995Journal of Clinical Investigation91 citations Open access
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Correction of renal tubular acidosis in carbonic anhydrase II-deficient mice with gene therapy.
L. Lai, Deva M. Chan, R. Erickson, S. J. Hsu +1 more
1998Journal of Clinical Investigation88 citations Open access
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Effects of cinacalcet on bone mineral density in patients with secondary hyperparathyroidism.
Y. Lien, A. Silva, D. Whittman
2005Nephrology, Dialysis and Transplantation73 citations
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Effects of furosemide on renal calcium handling.
Chien-Te Lee, Hung C. Chen, L. Lai, Kim-Chong Yong +1 more
2007AJP - Renal Physiology71 citations
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Increased renal calcium and magnesium transporter abundance in streptozotocin-induced diabetes mellitus.
C.-T. Lee, Y. Lien, L. Lai, J.-B. Chen +2 more
2006Kidney International71 citations Open access
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Pharmacologic recruitment of regulatory T cells as a novel therapy for ischemic acute kidney injury
L. Lai, Kim-Chong Yong, Y. Lien
2011Kidney International69 citations Open access
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Cyclosporine A-induced hypercalciuria in calbindin-D28k knockout and wild-type mice.
Chien-Te Lee, V. M. Huỳnh, L. Lai, Y. Lien
2002Kidney International65 citations Open access
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Is bowel preparation before colonoscopy a risky business for the kidney?
Y. Lien
2008Nature Clinical Practice Nephrology62 citations
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Biochemical and molecular genetic basis of Fabry disease.
G. Pastores, Y. Lien
2002Journal of the American Society of Nephrology62 citations
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Effect of thiazide on renal gene expression of apical calcium channels and calbindins.
Chien-Te Lee, S. Shang, L. Lai, Kim-Chong Yong +1 more
2004AJP - Renal Physiology55 citations
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Effects of Cyclosporine, Tacrolimus and Rapamycin on Renal Calcium Transport and Vitamin D Metabolism
Chien-Te Lee, Hwee-Yeong Ng, Y. Lien, L. Lai +3 more
2011American Journal of Nephrology54 citations Open access
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Phenotypic Characteristics of Bone in Carbonic Anhydrase II-Deficient Mice
D. S. Margolis, J. Szivek, L. Lai, Y. Lien
2008Calcified Tissue International52 citations
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Looking for Sarcopenia Biomarkers.
Y. Lien
2017American Journal of Medicine48 citations
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Long-term cyclophosphamide treatment for recurrent type I membranoproliferative glomerulonephritis after transplantation.
Y. Lien, K. Scott
2000American Journal of Kidney Diseases44 citations
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Pharmacokinetics of single, oral-dose voriconazole in peritoneal dialysis patients.
Lu Peng, Y. Lien
2005American Journal of Kidney Diseases39 citations
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Agalsidase alfa in pediatric patients with Fabry disease: a 6.5-year open-label follow-up study
R. Schiffmann, G. Pastores, Y. Lien, Victoria Castaneda +3 more
2014Orphanet Journal of Rare Diseases38 citations Open access
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Respiratory acidosis in carbonic anhydrase II-deficient mice.
Y. Lien, L. Lai
1998American Journal of Physiology - Lung cellular and Molecular Physiology36 citations
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Analysis of splice‐site mutations of the α‐galactosidase A gene in Fabry disease
L. Lai, O. Whitehair, M.-J. Wu, M. O'Meara +1 more
200333 citations
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Homologous Recombination Based Gene Therapy
L. Lai, Y. Lien
1999Nephron Experimental Nephrology31 citations
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Liposome-mediated gene transfer into the tubules.
Y. Lien, L. Lai
1997Experimental nephrology31 citations
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The role of calbindin-D28k on renal calcium and magnesium handling during treatment with loop and thiazide diuretics.
Chien-Te Lee, Hwee-Yeong Ng, Yueh-Ting Lee, L. Lai +1 more
2016AJP - Renal Physiology30 citations Open access
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Multicentric papillary renal carcinoma in renal allograft.
M. Delong, Dasan Schmitt, K. Scott, S. Ramakumar +1 more
2003American Journal of Kidney Diseases29 citations
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Gene therapy for renal diseases.
Y. Lien, L. Lai
1997Kidney international. Supplement28 citations
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Cinacalcet-associated graft dysfunction and nephrocalcinosis in a kidney transplant recipient.
Lu Peng, J. Logan, S. James, K. Scott +1 more
2007American Journal of Medicine27 citations Open access
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Reabsorption of betaine in Henle's loops of rat kidney in vivo.
Stefan Pummer, W. Dantzler, Y. Lien, G. Moeckel +2 more
2000AJP - Renal Physiology27 citations
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Scyllo-inositol depletion in hepatic encephalopathy.
Y. Lien, T. Michaelis, R. Moats, B. Ross
1994Life Science27 citations
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Renin-angiotensin blockade reduces serum free testosterone in middle-aged men on haemodialysis and correlates with erythropoietin resistance.
M. Delong, J. Logan, Kim-Chong Yong, Y. Lien
2005Nephrology, Dialysis and Transplantation26 citations
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Distribution of de novo synthesized betaine in rat kidney: role of renal synthesis on medullary betaine accumulation.
G. Moeckel, Y. Lien
1997American Journal of Physiology26 citations
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Antidepressants and Hyponatremia.
Y. Lien
2018American Journal of Medicine25 citations
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Effect of calbindin‐D28K on cyclosporine toxicity in cultured renal proximal tubular cells
Ming-Ju Wu, L. Lai, Y. Lien
2004Journal of Cellular Physiology21 citations
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Renal Adaptation to Gentamicin-Induced Mineral Loss
Chien-Te Lee, Hung C. Chen, Hwee-Yeong Ng, L. Lai +1 more
2012American Journal of Nephrology20 citations Open access
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Functionally improved bone in calbindin-D28k knockout mice.
D. S. Margolis, Devin Kim, J. Szivek, L. Lai +1 more
2006Bone20 citations Open access
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Analysis of splice-site mutations of the alpha-galactosidase A gene in Fabry disease.
L. Lai, O. Whitehair, M.-J. Wu, M. O'Meara +1 more
2003Clinical Genetics20 citations
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Bilateral femoral head and distal tibial osteonecrosis in a patient with Fabry disease.
Y. Lien, L. Lai
2005American journal of orthopedics18 citations
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Bilateral symmetry of biomechanical properties in mouse femora.
D. S. Margolis, Y. Lien, L. Lai, J. Szivek
2004Medical Engineering and Physics18 citations
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Two novel mutations in the α‐galactosidase A gene in Chinese patients with Fabry disease
Chih-Chao Yang, L. Lai, O. Whitehair, W. Hwu +2 more
200318 citations
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A novel α-galactosidase a mutant (M42L) identified in a renal variant of Fabry disease
D. Rosenthal, Y. Lien, D. Lager, L. Lai +3 more
200417 citations
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Cross-Reactions Between Allopurinol and Febuxostat.
Y. Lien, J. Logan
2017American Journal of Medicine16 citations Open access
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Effect and Tolerability of Agalsidase Alfa in Patients with Fabry Disease Who Were Treatment Naïve or Formerly Treated with Agalsidase Beta or Agalsidase Alfa.
O. Goker-Alpan, K. Nedd, S. Shankar, Y. Lien +4 more
2015JIMD Reports16 citations Open access
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Cytoprotective effects of calbindin-D(28k) against antimycin-A induced hypoxic injury in proximal tubular cells.
Ming-Ju Wu, L. Lai, Y. Lien
2002Life Science15 citations
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Juicing is not all juicy.
Y. Lien
2013American Journal of Medicine14 citations Open access
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A novel alpha-galactosidase a mutant (M42L) identified in a renal variant of Fabry disease.
D. Rosenthal, Y. Lien, D. Lager, L. Lai +3 more
2004American Journal of Kidney Diseases14 citations
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Promoter activity of carbonic anhydrase II regulatory regions in cultured renal proximal tubular cells.
L. Lai, R. Erickson, P. Venta, R. Tashian +1 more
1998Life Science14 citations
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Top 10 Things Primary Care Physicians Should Know About Maintenance Immunosuppression for Transplant Recipients.
Y. Lien
2016American Journal of Medicine13 citations
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Variations of Dietary Salt and Fluid Modulate Calcium and Magnesium Transport in Renal Distal Tubule
Chien-Te Lee, Y. Lien, L. Lai, Hwee-Yeong Ng +2 more
2013Nephron Physiology12 citations Open access
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