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Jian-Min C. Chen · SciRah

Researcher profile · Semantic Scholar

Jian-Min C. Chen

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Jian-Min C. Chen — researcher profile on SciRah

h-index: 29
Works: 66
Citations: 2,763

Most-cited papers

Dietary Flaxseed Alters Tumor Biological Markers in Postmenopausal Breast Cancer
L. Thompson, Jian-Min C. Chen, Tong Li, K. Strasser-Weippl +1 more
2005Clinical Cancer Research258 citations
Semantic Scholar
Dietary Flaxseed Inhibits Human Breast Cancer Growth and Metastasis and Downregulates Expression of Insulin-Like Growth Factor and Epidermal Growth Factor Receptor
Jian-Min C. Chen, P. Stavro, L. Thompson
2002Nutrition and Cancer208 citations
Semantic Scholar
Flaxseed inhibits metastasis and decreases extracellular vascular endothelial growth factor in human breast cancer xenografts.
C. Dabrosin, Jian-Min C. Chen, Linda Wang, L. Thompson
2002Cancer Letters159 citations
Semantic Scholar
Effect of maternal and postweaning folic acid supplementation on mammary tumor risk in the offspring.
Anna Ly, Hanna Lee, Jian-Min C. Chen, Karen K Y Sie +6 more
2011Cancer Research134 citations Open access
Semantic Scholar
The inhibitory effect of flaxseed on the growth and metastasisof estrogen receptor negative human breast cancer xenograftsis attributed to both its lignan and oil components
Linda Wang, Jian-Min C. Chen, L. Thompson
2005International Journal of Cancer134 citations
Semantic Scholar
Biochemical and Molecular Roles of Nutrients Flaxseed and Its Lignan Precursor , Secoisolariciresinol Diglycoside , Affect Pregnancy Outcome and Reproductive Development in Rats 1 , 2 , 3
Janet C. Tou, Jian-Min C. Chen, L. Thompson
1998130 citations
Semantic Scholar
Dietary Flaxseed Enhances the Inhibitory Effect of Tamoxifen on the Growth of Estrogen-Dependent Human Breast Cancer (MCF-7) in Nude Mice
Jian-Min C. Chen, E. Hui, Terence Ip, L. Thompson
2004Clinical Cancer Research108 citations Open access
Semantic Scholar
Flaxseed and its components reduce metastasis after surgical excision of solid human breast tumor in nude mice.
Jian-Min C. Chen, Linda Wang, L. Thompson
2006Cancer Letters99 citations
Semantic Scholar
Lignans and Tamoxifen, Alone or in Combination, Reduce Human Breast Cancer Cell Adhesion, Invasion and Migration in vitro
Jian-Min C. Chen, L. Thompson
2003Breast Cancer Research and Treatment96 citations
Semantic Scholar
Flaxseed oil reduces the growth of human breast tumors (MCF-7) at high levels of circulating estrogen.
Jennifer S Truan, Jian-Min C. Chen, L. Thompson
2010Molecular Nutrition & Food Research91 citations
Semantic Scholar
Exposure to Flaxseed or Its Purified Lignan during Suckling Inhibits Chemically Induced Rat Mammary Tumorigenesis
Jian-Min C. Chen, Kah Poh Tan, W. Ward, L. Thompson
2003Experimental biology and medicine88 citations
Semantic Scholar
Dose effects of flaxseed and its lignan on N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats.
S. Rickard, Y. Yuan, Jian-Min C. Chen, L. Thompson
1999Nutrition and Cancer85 citations
Semantic Scholar
Dose, timing, and duration of flaxseed exposure affect reproductive indices and sex hormone levels in rats.
Janet C. Tou, Jian-Min C. Chen, Lilian U. Thompson
1999Journal of Toxicology and Environmental Health, Part A83 citations
Semantic Scholar
Flaxseed and pure secoisolariciresinol diglucoside, but not flaxseed hull, reduce human breast tumor growth (MCF-7) in athymic mice.
Jian-Min C. Chen, J. Saggar, P. Corey, L. Thompson
2009Journal of NutriLife79 citations Open access
Semantic Scholar
Flaxseed Alone or in Combination with Tamoxifen Inhibits MCF-7 Breast Tumor Growth in Ovariectomized Athymic Mice with High Circulating Levels of Estrogen
Jian-Min C. Chen, Krista A. Power, J. Mann, Astor Cheng +1 more
2007Experimental biology and medicine75 citations
Semantic Scholar
Mammalian lignans enterolactone and enterodiol, alone and in combination with the isoflavone genistein, do not promote the growth of MCF‐7 xenografts in ovariectomized athymic nude mice
Krista A. Power, N. Saarinen, Jian-Min C. Chen, L. Thompson
2006International Journal of Cancer75 citations Open access
Semantic Scholar
Comparative Effects of Sesame Seed Lignan and Flaxseed Lignan in Reducing the Growth of Human Breast Tumors (MCF-7) at High Levels of Circulating Estrogen in Athymic Mice
Jennifer S Truan, Jian-Min C. Chen, L. Thompson
2012Nutrition and Cancer73 citations
Semantic Scholar
Dietary flaxseed lignan or oil combined with tamoxifen treatment affects MCF-7 tumor growth through estrogen receptor- and growth factor-signaling pathways.
J. Saggar, Jian-Min C. Chen, P. Corey, L. Thompson
2010Molecular Nutrition & Food Research70 citations
Semantic Scholar
Flaxseed attenuates the tumor growth stimulating effect of soy protein in ovariectomized athymic mice with MCF‐7 human breast cancer xenografts
N. Saarinen, Krista A. Power, Jian-Min C. Chen, L. Thompson
2006International Journal of Cancer70 citations Open access
Semantic Scholar
Mammary Gland Morphogenesis is Enhanced by Exposure to Flaxseed or Its Major Lignan During Suckling in Rats
Kah Poh Tan, Jian-Min C. Chen, W. Ward, L. Thompson
2004Experimental biology and medicine63 citations
Semantic Scholar
The Effect of Secoisolariciresinol Diglucoside and Flaxseed Oil, Alone and in Combination, on MCF-7 Tumor Growth and Signaling Pathways
J. Saggar, Jian-Min C. Chen, P. Corey, L. Thompson
2010Nutrition and Cancer59 citations
Semantic Scholar
Flaxseed oil-trastuzumab interaction in breast cancer.
J. Mason, Jian-Min C. Chen, L. Thompson
2010Food and Chemical Toxicology43 citations
Semantic Scholar
Dietary Flaxseed Interaction With Tamoxifen Induced Tumor Regression in Athymic Mice With MCF-7 Xenografts by Downregulating the Expression of Estrogen Related Gene Products and Signal Transduction Pathways
Jian-Min C. Chen, Krista A. Power, J. Mann, Astor Cheng +1 more
2007Nutrition and Cancer41 citations
Semantic Scholar
Low vitamin D status throughout life results in an inflammatory prone status but does not alter bone mineral or strength in healthy 3-month-old CD-1 male mice.
Raha Jahani, Kristina A. Fielding, Jian-Min C. Chen, C. Villa +3 more
2014Molecular Nutrition & Food Research38 citations
Semantic Scholar
Folic acid supplementation provided in utero and during lactation reduces the number of terminal end buds of the developing mammary glands in the offspring.
Karen K Y Sie, Jian-Min C. Chen, Kyong-Jin Sohn, R. Croxford +2 more
2009Cancer Letters37 citations
Semantic Scholar
Flaxseed oil enhances the effectiveness of trastuzumab in reducing the growth of HER2-overexpressing human breast tumors (BT-474).
J. Mason, M. Fu, Jian-Min C. Chen, L. Thompson
2015Journal of Nutritional Biochemistry33 citations
Semantic Scholar
Genistein alone and in combination with the mammalian lignans enterolactone and enterodiol induce estrogenic effects on bone and uterus in a postmenopausal breast cancer mouse model.
Krista A. Power, W. Ward, Jian-Min C. Chen, N. Saarinen +1 more
2006Bone33 citations
Semantic Scholar
Sialomucin production in aberrant crypt foci relates to degree of dysplasia and rate of cell proliferation.
M. Jenab, Jian-Min C. Chen, Lilian U. Thompson
2001Cancer Letters32 citations
Semantic Scholar
Flaxseed cotyledon fraction reduces tumour growth and sensitises tamoxifen treatment of human breast cancer xenograft (MCF-7) in athymic mice
Jian-Min C. Chen, J. Saggar, P. Corey, L. Thompson
2010British Journal of Nutrition30 citations Open access
Semantic Scholar
Changes in biomarkers of estrogen receptor and growth factor signaling pathways in MCF-7 tumors after short- and long-term treatment with soy and flaxseed.
Krista A. Power, Jian-Min C. Chen, N. Saarinen, L. Thompson
2008Journal of Steroid Biochemistry and Molecular Biology29 citations
Semantic Scholar
Early Life Exposure to Genistein and Daidzein Disrupts Structural Development of Reproductive Organs in Female Mice
J. Kaludjerovic, Jian-Min C. Chen, W. Ward
2012Journal of Toxicology and Environmental Health, Part A20 citations Open access
Semantic Scholar
Effect of dietary protein levels on growth performance and whole body composition of summerling and winterling spotted barbel (Hemibarbus maculates Bleeker)
Jian-Min C. Chen, Jinyun Ye, Q. Pan, Bin-Qian Shen +1 more
200920 citations
Semantic Scholar
Effects of Flaxseed Lignan and Oil on Bone Health of Breast-Tumor-Bearing Mice Treated With or Without Tamoxifen
Jian-Min C. Chen, J. Saggar, W. Ward, L. Thompson
2011Journal of Toxicology and Environmental Health, Part A18 citations
Semantic Scholar
Lignans are Accessible to Human Breast Cancer Xenografts in Athymic Mice
N. Saarinen, Krista A. Power, Jian-Min C. Chen, L. Thompson
2008Nutrition and Cancer18 citations
Semantic Scholar
Time‐ and strain‐specific downregulation of intestinal EPAS1 via miR‐148a by Bifidobacterium bifidum
A. Taibi, Natasha Singh, Jian-Min C. Chen, S. Arioli +2 more
2017Molecular Nutrition & Food Research17 citations Open access
Semantic Scholar
Long-Term Vitamin D3 Supplementation Does Not Prevent Colonic Inflammation or Modulate Bone Health in IL-10 Knockout Mice at Young Adulthood
Andrea J. Glenn, Kristina A. Fielding, Jian-Min C. Chen, E. Comelli +1 more
2014Nutrients17 citations Open access
Semantic Scholar
Flaxseed and Soy Protein Isolate, Alone and in Combination, Differ in their Effect on Bone Mass, Biomechanical Strength, and Uterus in Ovariectomized Nude Mice with MCF-7 Human Breast Tumor Xenografts
Krista A. Power, W. Ward, Jian-Min C. Chen, N. Saarinen +1 more
2007Journal of Toxicology and Environmental Health, Part A17 citations
Semantic Scholar
Lignan-rich sesame seed negates the tumor-inhibitory effect of tamoxifen but maintains bone health in a postmenopausal athymic mouse model with estrogen-responsive breast tumors
S. Sacco, Jian-Min C. Chen, Krista A. Power, W. Ward +1 more
2007Menopause15 citations
Semantic Scholar
Interaction of Sesame Seed and Tamoxifen on Tumor Growth and Bone Health in Athymic Mice
S. Sacco, Krista A. Power, Jian-Min C. Chen, W. Ward +1 more
2007Experimental biology and medicine15 citations
Semantic Scholar
Maternal Dietary Vitamin D Does Not Program Systemic Inflammation and Bone Health in Adult Female Mice Fed an Obesogenic Diet
C. Villa, Jian-Min C. Chen, B. Wen, S. Sacco +3 more
2016Nutrients14 citations Open access
Semantic Scholar
Dietary Flaxseed–Trastuzumab Interactive Effects on the Growth of HER2-Overexpressing Human Breast Tumors (BT-474)
J. Mason, M. Fu, Jian-Min C. Chen, Zhe Yu +1 more
2013Nutrition and Cancer14 citations
Semantic Scholar
Early life exposure to isoflavones adversely affects reproductive health in first but not second generation female CD-1 mice.
Elsa C. Dinsdale, Jian-Min C. Chen, W. Ward
2011Journal of NutriLife13 citations Open access
Semantic Scholar
Flaxseed enhances the beneficial effect of low-dose estrogen therapy at reducing bone turnover and preserving bone microarchitecture in ovariectomized rats.
S. Sacco, Jian-Min C. Chen, B. Ganss, L. Thompson +1 more
2014Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme12 citations Open access
Semantic Scholar
17β-Estradiol Increases Liver and Serum Docosahexaenoic Acid in Mice Fed Varying Levels of α-Linolenic Acid
J. Mason, Shikhil Kharotia, Ashleigh K. A. Wiggins, Alex P. Kitson +3 more
2014Lipids11 citations
Semantic Scholar
Citrobacter rodentium alters the mouse colonic miRNome
B. Wen, T. Tokár, A. Taibi, Jian-Min C. Chen +2 more
2018Genes and Immunity5 citations
Semantic Scholar
Low Dietary Vitamin D since Pre‐mating Does not Modify Fecal Bacteroides Counts of Mouse Dams at the End of Pregnancy
C. Villa, A. Taibi, Shivani Kasee, Jian-Min C. Chen +2 more
2017The FASEB Journal1 citations
Semantic Scholar
Abstract 3486: Interaction of flaxseed oil with trastuzumab in HER2 overexpressing human breast tumors (BT-474)
J. Mason, Jian-Min C. Chen, L. Thompson
20101 citations
Semantic Scholar
The Effect of Sesame Lignan and Flaxseed Lignan and Oil on the Growth of Human Estrogen Receptor‐Positive Breast Tumors (MCF‐7)
Jennifer S Truan, Jian-Min C. Chen, L. Thompson
20091 citations
Semantic Scholar
Effect of Low Dietary Vitamin D Fed Prior to and During Pregnancy and Lactation on Maternal Bone Mineral Density, Structure, and Strength in C57BL/6 Mice
C. Villa, S. Sacco, Jian-Min C. Chen, A. Taibi +2 more
2021Current Developments in Nutrition0 citations Open access
Semantic Scholar
Low Dietary Vitamin D with a Regular Level of Calcium Prior To and During Pregnancy and Lactation Has No Effect on Trabecular Bone Structure of Mouse Dams
C. Villa, S. Sacco, Jian-Min C. Chen, E. Comelli +1 more
2017The FASEB Journal0 citations Open access
Semantic Scholar

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