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J. Korkola · SciRah

Researcher profile · Semantic Scholar

J. Korkola

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J. Korkola — researcher profile on SciRah

h-index: 35
Works: 115
Citations: 5,425

Most-cited papers

Subtype and pathway specific responses to anticancer compounds in breast cancer
L. Heiser, A. Sadanandam, Wen-Lin Kuo, S. Benz +39 more
2011Proceedings of the National Academy of Sciences of the United States of America482 citations Open access
Semantic Scholar
The Library of Integrated Network-based Cellular Signatures (LINCS) NIH Program: System-level Cataloging of Human Cells Response to Perturbations
A. Keenan, Sherry L. Jenkins, K. Jagodnik, Simon Koplev +103 more
2017Cell Systems391 citations Open access
Semantic Scholar
A Central Role for RAF→MEK→ERK Signaling in the Genesis of Pancreatic Ductal Adenocarcinoma.
E. Collisson, Christy L. Trejo, Jillian M. Silva, Shenda Gu +10 more
2012Cancer Discovery299 citations Open access
Semantic Scholar
Cell fusion potentiates tumor heterogeneity and reveals circulating hybrid cells that correlate with stage and survival
C. Gast, Alain D. Silk, L. Zarour, L. Riegler +24 more
2018Science Advances286 citations Open access
Semantic Scholar
Modeling precision treatment of breast cancer
A. Daemen, O. Griffith, L. Heiser, Nicholas Wang +23 more
2013Genome Biology278 citations Open access
Semantic Scholar
Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting
Ellen M. Langer, Brittany L. Allen-Petersen, S. King, Nicholas D. Kendsersky +15 more
2019Cell Reports220 citations Open access
Semantic Scholar
Cellular senescence in cancer: from mechanisms to detection
H. Ou, R. Hoffmann, Cristina González-López, G. Doherty +2 more
2020Molecular Oncology177 citations Open access
Semantic Scholar
A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines
M. Niepel, M. Hafner, Caitlin E. Mills, K. Subramanian +31 more
2019Cell Systems126 citations Open access
Semantic Scholar
CCR5 governs DNA damage repair and breast cancer stem cell expansion
X. Jiao, M. Velasco-Velázquez, Min Wang, Zhi-Ping Li +19 more
2018Cancer Research121 citations Open access
Semantic Scholar
Exome Sequencing of Cell-Free DNA from Metastatic Cancer Patients Identifies Clinically Actionable Mutations Distinct from Primary Disease
T. Butler, Katie Johnson-Camacho, M. Peto, Nicholas Wang +6 more
2015PLoS ONE112 citations Open access
Semantic Scholar
Kinome rewiring reveals AURKA limits PI3K-pathway inhibitor efficacy in breast cancer
Hayley J. Donnella, James T. Webber, Rebecca S. Levin, R. Camarda +8 more
2018Nature Chemical Biology82 citations Open access
Semantic Scholar
Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes
S. Watson, Mark A. Dane, K. Chin, Zuzana Tatarova +14 more
2018Cell Systems81 citations Open access
Semantic Scholar
A Genetic Strategy for Single and Combinatorial Analysis of miRNA Function in Mammalian Hematopoietic Stem Cells
E. Papapetrou, J. Korkola, M. Sadelain
2009Stem Cells80 citations
Semantic Scholar
Testicular mixed germ cell tumors: a morphological and immunohistochemical study using stem cell markers, OCT3/4, SOX2 and GDF3, with emphasis on morphologically difficult-to-classify areas
A. Gopalan, D. Dhall, Semra Olgac, S. Fine +6 more
2009Modern Pathology80 citations Open access
Semantic Scholar
The Transcription Factor ZNF217 Is a Prognostic Biomarker and Therapeutic Target during Breast Cancer Progression
L. Littlepage, A. Adler, H. Kouros-Mehr, Guiqing Huang +16 more
2012Cancer Discovery76 citations Open access
Semantic Scholar
Identification and validation of a gene expression signature that predicts outcome in adult men with germ cell tumors.
J. Korkola, J. Houldsworth, D. Feldman, A. Olshen +5 more
2009Journal of Clinical Oncology75 citations Open access
Semantic Scholar
Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib
A. Daemen, D. Wolf, J. Korkola, O. Griffith +11 more
2012Breast Cancer Research and Treatment72 citations Open access
Semantic Scholar
Causal network inference using biochemical kinetics
Chris J. Oates, F. Dondelinger, N. Bayani, J. Korkola +2 more
2014Bioinform.62 citations Open access
Semantic Scholar
In vivo differentiation and genomic evolution in adult male germ cell tumors
J. Korkola, S. Heck, A. Olshen, V. Reuter +3 more
2008Genes, Chromosomes and Cancer61 citations Open access
Semantic Scholar
Enzalutamide response in a panel of prostate cancer cell lines reveals a role for glucocorticoid receptor in enzalutamide resistant disease
Rebecca Smith, Moqing Liu, T. Liby, N. Bayani +9 more
2020Scientific Reports60 citations Open access
Semantic Scholar
Breast cancer genomes — form and function
J. Korkola, J. Gray
2010Current Opinion in Genetics and Development57 citations Open access
Semantic Scholar
Context-specificity in causal signaling networks revealed by phosphoprotein profiling
S. Hill, Nicole K. Nesser, Katie Johnson-Camacho, M. Jeffress +12 more
2016bioRxiv45 citations Open access
Semantic Scholar
Identification of a robust gene signature that predicts breast cancer outcome in independent data sets
J. Korkola, E. Blaveri, S. Devries, D. H. Ii Moore +6 more
2007BMC Cancer45 citations Open access
Semantic Scholar
Quantification of sensitivity and resistance of breast cancer cell lines to anti-cancer drugs using GR metrics
M. Hafner, L. Heiser, Elizabeth H. Williams, M. Niepel +4 more
2017Scientific Data44 citations Open access
Semantic Scholar
A multiplex implantable microdevice assay identifies synergistic combinations of cancer immunotherapies and conventional drugs
Zuzana Tatarova, Dylan C. Blumberg, J. Korkola, L. Heiser +7 more
2022Nature Biotechnology42 citations Open access
Semantic Scholar
Maintenance of MYC expression promotes de novo resistance to BET bromodomain inhibition in castration-resistant prostate cancer
Daniel J. Coleman, Li-Na Gao, Jacob Schwartzman, J. Korkola +9 more
2019Scientific Reports37 citations Open access
Semantic Scholar
Interrogation of a Context-Specific Transcription Factor Network Identifies Novel Regulators of Pluripotency
Ritu Kushwaha, Nirmala Jagadish, Manjunath Kustagi, M. Tomishima +14 more
2015Stem Cells35 citations Open access
Semantic Scholar
Identification and Quantification of AKT Isoforms and Phosphoforms in Breast Cancer Using a Novel Nanofluidic Immunoassay*
Demetris Iacovides, Aimee B. Johnson, Nicholas Wang, Shanta P. Boddapati +2 more
2013Molecular & Cellular Proteomics33 citations Open access
Semantic Scholar
Ferrous iron–activatable drug conjugate achieves potent MAPK blockade in KRAS-driven tumors
Hong-Lin Jiang, Ryan K. Muir, Ryan L. Gonciarz, A. Olshen +9 more
2022Journal of Experimental Medicine28 citations Open access
Semantic Scholar
Molecular events in germ cell tumours: linking chromosome‐12 gain, acquisition of pluripotency and response to cisplatin
J. Korkola, J. Houldsworth, G. Bosl, R. S. K. Chaganti
2009BJU International26 citations
Semantic Scholar
A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses
Sean M. Gross, Mark A. Dane, Rebecca Smith, Kaylyn L. Devlin +46 more
2022Communications Biology24 citations Open access
Semantic Scholar
Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer
J. Korkola, E. Collisson, L. Heiser, Chris J. Oates +19 more
2015PLoS ONE24 citations Open access
Semantic Scholar
Using microarrays to interrogate microenvironmental impact on cellular phenotypes in cancer.
Rebecca Smith, Kaylyn L. Devlin, David Kilburn, Sean M. Gross +7 more
2019Journal of Visualized Experiments20 citations Open access
Semantic Scholar
Targeting mitochondria in cancer therapy could provide a basis for the selective anti-cancer activity
D. Rozanov, Anton V. Cheltsov, Aaron Nilsen, C. Boniface +7 more
2018bioRxiv20 citations Open access
Semantic Scholar
Joint estimation of multiple networks from time course data
Chris J. Oates, J. Korkola, J. Gray, S. Mukherjee
201320 citations Open access
Semantic Scholar
Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer
Zhi Hu, Jian-Hua Mao, C. Curtis, Ge Huang +21 more
2016Breast Cancer Research18 citations Open access
Semantic Scholar
Development and Validation of a Gene-Based Model for Outcome Prediction in Germ Cell Tumors Using a Combined Genomic and Expression Profiling Approach
J. Korkola, S. Heck, A. Olshen, D. Feldman +4 more
2015PLoS ONE18 citations Open access
Semantic Scholar
Urinary Comprehensive Genomic Profiling Correlates Urothelial Carcinoma Mutations with Clinical Risk and Efficacy of Intervention
V. Bicocca, Kevin G. Phillips, Daniel Fischer, Vincent M Caruso +10 more
2022Journal of Clinical Medicine17 citations Open access
Semantic Scholar
Sensitivity to targeted therapy differs between HER2-amplified breast cancer cells harboring kinase and helical domain mutations in PIK3CA
J. Garay, Rebecca Smith, Kaylyn L. Devlin, D. Hollern +13 more
2021Breast Cancer Research17 citations Open access
Semantic Scholar
Cellular androgen content influences enzalutamide agonism of F877L mutant androgen receptor
Daniel J. Coleman, Kathryn Van Hook, Carly J. King, Jacob Schwartzman +13 more
2016OncoTarget16 citations Open access
Semantic Scholar
An altered extracellular matrix–integrin interface contributes to Huntington’s disease-associated CNS dysfunction in glial and vascular cells
Sarah J. Hernandez, Ryan G. Lim, T. Onur, Mark A. Dane +15 more
2022Human Molecular Genetics15 citations Open access
Semantic Scholar
INHBA is a mediator of aggressive tumor behavior in HER2+ basal breast cancer
Moqing Liu, Rebecca B Smith, T. Liby, K. Chiotti +2 more
2022Breast Cancer Research14 citations Open access
Semantic Scholar
Mechanism and Role of SOX2 Repression in Seminoma: Relevance to Human Germline Specification
Ritu Kushwaha, Nirmala Jagadish, Manjunath Kustagi, G. Mendiratta +7 more
2016Stem Cell Reports13 citations Open access
Semantic Scholar
Constitutive Gene Expression Predisposes Morphogen‐Mediated Cell Fate Responses of NT2/D1 and 27X‐1 Human Embryonal Carcinoma Cells
R. S. Chadalavada, J. Korkola, J. Houldsworth, A. Olshen +3 more
2007Stem Cells12 citations
Semantic Scholar
Automatic Transformation and Integration to Improve Visualization and Discovery of Latent Effects in Imaging Data
Gregory J. Hunt, Mark A. Dane, J. Korkola, L. Heiser +1 more
2020Journal of Computational And Graphical Statistics11 citations Open access
Semantic Scholar
Crosstalk between invadopodia and the extracellular matrix
S. Iizuka, Ronald P. Leon, K. Gribbin, Ying Zhang +8 more
2020bioRxiv10 citations Open access
Semantic Scholar
Crosstalk between invadopodia and the extracellular matrix.
S. Iizuka, Ronald P. Leon, K. Gribbin, Ying Zhang +8 more
2020European Journal of Cell Biology9 citations Open access
Semantic Scholar
Expanding the Diversity of Imaging-Based RNAi Screen Applications Using Cell Spot Microarrays
J. Rantala, Sunjong Kwon, J. Korkola, J. Gray
2013Microarrays9 citations Open access
Semantic Scholar
Computational drug repositioning for the identification of new agents to sensitize drug-resistant breast tumors across treatments and receptor subtypes
K. Yu, A. Basu, C. Yau, D. Wolf +11 more
2023bioRxiv8 citations Open access
Semantic Scholar
Transcriptional signatures in histologic structures within glioblastoma tumors may predict personalized drug sensitivity and survival
C. Kersch, C. Claunch, P. Ambady, Elmar Bucher +9 more
2020Neuro-Oncology Advances7 citations Open access
Semantic Scholar

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